AutismKB 2.0

Annotation Detail for PGD


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Basic Information Top
Gene Symbol:PGD ( 6PGD )
Gene Full Name: phosphogluconate dehydrogenase
Band: 1p36.22
Quick LinksEntrez ID:5226; OMIM: 172200; Uniprot ID:6PGD_HUMAN; ENSEMBL ID: ENSG00000142657; HGNC ID: 8891
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PENTOSE-P-PWYpentose phosphate pathway
OXIDATIVEPENT-PWYpentose phosphate pathway (oxidative branch)
Pathway IDPathway Name
hsa00480Glutathione metabolism
hsa00030Pentose phosphate pathway
hsa01100Metabolic pathways
Pathway IDPathway Name
Metabolism of carbohydrates
No data
Pathway IDPathway Name
P02762Pentose phosphate pathway
Pathway IDPathway Name
500683Pentose phosphate pathway (hexose monophosphate shunt)
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C018855 2-tert-butylhydroquinone 2-tert-butylhydroquinone results in increased expression of PGD mRNAincreases expression 16014739
C016392 3,3'-diindolylmethane 3,3'-diindolylmethane results in decreased expression of PGD mRNAdecreases expression 16192472
C029728 4-phenylenediamine 4-phenylenediamine results in increased expression of PGD mRNAincreases expression 16314067
D000082 Acetaminophen Acetaminophen affects the expression of PGD mRNAaffects expression 17562736
D000583 Amikacin Amikacin results in decreased activity of PGD proteindecreases activity 15558954
D000667 Ampicillin Ampicillin results in decreased activity of PGD proteindecreases activity 15558954
C006632 arsenic trioxide arsenic trioxide results in increased expression of PGD mRNAincreases expression 20458559
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of PGD mRNAaffects expression 17484886
C043266 cefepime cefepime results in decreased activity of PGD proteindecreases activity 15558954
D002439 Cefotaxime Cefotaxime results in decreased activity of PGD proteindecreases activity 15558954
C041078 ceftazidime monobactam ceftazidime monobactam results in decreased activity of PGD proteindecreases activity 15558954
D002701 Chloramphenicol Chloramphenicol results in decreased activity of PGD proteindecreases activity 15558954
D002939 Ciprofloxacin Ciprofloxacin results in decreased activity of PGD proteindecreases activity 15558954
D009249 NADP NADP results in increased expression of PGD proteinincreases expression 1922005
D003474 Curcumin Curcumin results in increased expression of PGD mRNAincreases expression 18299980
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of PGD mRNAincreases expression 17654400
D016572 Cyclosporine Cyclosporine results in increased expression of PGD mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of PGD mRNAdecreases expression 18042831
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of PGD mRNAincreases expression 19638242
D004178 Diquat Diquat results in increased expression of PGD mRNAincreases expression 16962985
D004958 Estradiol Estradiol results in decreased expression of PGD mRNAdecreases expression 16192472
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of PGD mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PGD mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PGD mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PGD mRNAincreases expression 17557909
D005839 Gentamicins Gentamicins results in decreased activity of PGD proteindecreases activity 15558954
D017313 Fenretinide Fenretinide results in increased expression of PGD mRNAincreases expression 16671099
C016517 indole-3-carbinol indole-3-carbinol results in decreased expression of PGD mRNAdecreases expression 16192472
C016927 isepamicin isepamicin results in decreased activity of PGD proteindecreases activity 15558954
D007529 Isoflavones Isoflavones results in increased expression of PGD mRNAincreases expression 17374662
D008751 Methylene Blue Methylene Blue results in increased activity of PGD proteinincreases activity 1901343
C002950 methylformamide methylformamide affects the expression of PGD mRNAaffects expression 17040096
C002950 methylformamide methylformamide analog affects the expression of PGD mRNAaffects expression 17040096
C004925 methylmercuric chloride methylmercuric chloride results in increased expression of PGD mRNAincreases expression 17961207
D008773 Methylphenazonium Methosulfate Methylphenazonium Methosulfate results in increased activity of PGD proteinincreases activity 1901343
D009428 Netilmicin Netilmicin results in decreased activity of PGD proteindecreases activity 15558954
C029938 nickel sulfate nickel sulfate results in increased expression of PGD mRNAincreases expression 16314067
D015242 Ofloxacin Ofloxacin results in decreased activity of PGD proteindecreases activity 15558954
C041786 palm oil palm oil results in decreased expression of PGD mRNAdecreases expression 18042831
D010400 Penicillin G Penicillin G results in decreased activity of PGD proteindecreases activity 15558954
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of PGD mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of PGD mRNAincreases expression 19482888
C006253 pirinixic acid pirinixic acid results in increased expression of PGD mRNAincreases expression 18301758
C045950 propiconazole propiconazole results in increased expression of PGD mRNAincreases expression 19363144
D011758 Pyrroles Pyrroles results in increased activity of PGD proteinincreases activity 1901343
D013629 Tamoxifen Tamoxifen affects the expression of PGD mRNAaffects expression 17555576
D017334 Teicoplanin Teicoplanin results in decreased activity of PGD proteindecreases activity 15558954
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PGD mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin results in increased expression of PGD mRNAincreases expression 16140955
D014501 Uranium Uranium affects the expression of PGD mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of PGD mRNAaffects expression 15672453
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.0514745880
MESH:D000014 Abnormalities, Drug-Induced methylmercuric chloride 11.566734493
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.566195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.5615322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4517505938
MESH:D058186 Acute Kidney Injury Gentamicins 4.1111274264
MESH:D055371 Acute Lung Injury nickel sulfate 7.6612718980 11954676 16100012 19131640
MESH:D055371 Acute Lung Injury pirinixic acid 7.6618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 8.9719825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 8.9711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 8.9714692618
MESH:D000230 Adenocarcinoma Fenretinide 8.9710697514
MESH:D000236 Adenoma Diethylnitrosamine 2.5610737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 20.8617162532 19052882 18056438 19061943 17620307 16434500
MESH:D018248 Adenoma, Liver Cell Phenobarbital 20.8617620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 20.8616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 20.8616835633
MESH:D019973 Alcohol-Related Disorders Curcumin 4.5817887948
MESH:D000505 Alopecia Isoflavones 8.2917569567
MESH:D000505 Alopecia Tretinoin 8.2915955085
MESH:D000544 Alzheimer Disease Curcumin 2.5015590663
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5311748828
MESH:D000799 Angioedema Acetaminophen 3.3510982225
MESH:D000881 Anthrax Ciprofloxacin 6.2220385868
MESH:D016736 Antiphospholipid Syndrome Ciprofloxacin 6.229485080
MESH:D001161 Arteriosclerosis Dietary Fats 8.3315238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.3311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.1615885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.1616412693
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.2716807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.2716292516
MESH:D001249 Asthma Tretinoin 2.1816456186
MESH:D050197 Atherosclerosis Curcumin 3.0218704882
MESH:D001321 Autistic Disorder Acetaminophen 1.4818445737
MESH:D001327 Autoimmune Diseases Curcumin 4.0219761891
MESH:D001424 Bacterial Infections Ciprofloxacin 5.4011505790
MESH:D001471 Barrett Esophagus Tretinoin 3.9416935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.3716206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.3712125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 18.3716197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.2915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4415746008
MESH:D002545 Brain Ischemia Curcumin 3.8516770732
MESH:D001932 Brain Neoplasms Curcumin 7.7617596214
MESH:D001932 Brain Neoplasms Fenretinide 7.7616187019
MESH:D001943 Breast Neoplasms Curcumin 5.2218593918 19250217 16243823 18462866
MESH:D001943 Breast Neoplasms Dietary Fats 5.2220435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 5.2217474063
MESH:D001943 Breast Neoplasms Estradiol 5.2212948864 16675129 19861407 14630087 17018787 17261762 18497071 17289903
MESH:D001943 Breast Neoplasms Fenretinide 5.2216601279
MESH:D001943 Breast Neoplasms indole-3-carbinol 5.2216082211
MESH:D001943 Breast Neoplasms Tamoxifen 5.2218815881 19410462 16202921 20390343 19189212 19288272 19189210 19011961 19155303 19066611 19221464 21138602 18629630 16818667 20544844 17242785 19289846 17440819 19142967 21152245 19103187 19059307 18351453 19244106 19115204 17049068 11161223 20005174 15668708 20859285 18855134 19487384 18425577 18821012 20135344 18984771 17893378 17261762 15565566 16873071 18997820 19200415 19084267 20065188 16273361
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.2220435547
MESH:D001943 Breast Neoplasms Tretinoin 5.2216166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1016813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.8811589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.9816111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3116097048 16011737 16124888 15700767 15721981 10355542 16050911 15673190 16192424 3786805 18705752 16227642
MESH:D002277 Carcinoma Curcumin 7.0018593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.0016835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.0319066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6616168501
MESH:D006528 Carcinoma, Hepatocellular marker/mechanism 19363144
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 17.903084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 17.9015073043 16217749 11135700 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 17.9018788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 17.9019919837 18971187 18506893 16807293 20727157 20935162 20214788 10737359 18788625 19335982 16288022 19822196 16569478 20084675 19539802 18665156 17173139 16540662 16935385 16779866 17138121 11831363 17761372 21159647 19208518 19052882 20432363 3084413 10672840 18494052 18691550 17428255 19171122 18393292 17978847 16698587 19701751 19383236 16502159 19519916 16878318 19107877 20514400 3581430 16681979 20101231 16328049 18210153 18056438 18978308 17055752 18785209 17162532 20524982 19394651 20512989 16830150 19418558 20007298
MESH:D006528 Carcinoma, Hepatocellular Estradiol 17.9016924424
MESH:D006528 Carcinoma, Hepatocellular Fenretinide 17.9017159502 16270382
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 17.9020007298 17173139 1701930 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 17.9016924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 17.901917145
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.7918414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.3819014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.6912490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 6.7418462866
MESH:D002294 Carcinoma, Squamous Cell Fenretinide 6.7416274795
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 6.7416051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Ciprofloxacin 8.5210741713 15028437
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.5217572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.0916120746 18670907 18850075
MESH:D002318 Cardiovascular Diseases Isoflavones 3.8117689850
MESH:D002386 Cataract Acetaminophen 6.2310977129
MESH:D002386 Cataract Tretinoin 6.2317460283
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 9.1712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 9.1717174075 21159647 2727394 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 9.1718566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.784080065
MESH:D018290 Cervical Intraepithelial Neoplasia Fenretinide 11.3516154183
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 11.3516129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 7.9619052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.9616835633
MESH:D002779 Cholestasis Cyclosporine 11.2319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.2317681005 11677210 16919318 17333356 17110522 15861022 16105132
MESH:D002779 Cholestasis pirinixic acid 11.2319176532
MESH:D002822 Choriocarcinoma Tretinoin 4.6616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.028697196 12621046 15668235 15340226 16354765
MESH:D002972 Cleft Palate Tretinoin 5.029407595
MESH:D003092 Colitis Curcumin 8.0718200517 16782535 16804969
MESH:D003092 Colitis Tretinoin 8.0717035595
MESH:D003103 Coloboma Curcumin 4.1118809619
MESH:D003110 Colonic Neoplasms Curcumin 2.4216340194 19359593
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.3620501625
MESH:D015179 Colorectal Neoplasms Fenretinide 3.3617273769
MESH:D015179 Colorectal Neoplasms Isoflavones 3.3617116718
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6517141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.4218497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.3910525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.3910048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.399125849 10589399 9664655 8800419 9211117 16925845 14991402 17551590 9142499 9224671
MESH:D003550 Cystic Fibrosis Amikacin 12.6619747007
MESH:D003550 Cystic Fibrosis Ciprofloxacin 12.6619747007
MESH:D003550 Cystic Fibrosis Ofloxacin 12.6619747007
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6515213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.8919031437
MESH:D017449 Dermatitis, Allergic Contact 4-phenylenediamine 6.2816533241 16823706 11298694 19470301 11906362 18759875
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 6.2816780908 11298694 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.1818249437
MESH:D003877 Dermatitis, Contact 4-phenylenediamine 4.8911531941
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 6.2818403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.2820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.2817107852
MESH:D003928 Diabetic Nephropathies Curcumin 12.6618204486
MESH:D003928 Diabetic Nephropathies Estradiol 12.6619279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 12.6619279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 13.0412153990 19416960 11529661 11287661 12540782 16227642 19420014 15968718 11743745 11834606 19923254 17562736 16393943 14986274 14550746 16177239 10663392 19085960 19739265 19370779 2444490 12958197 12392966 12705907 14725611 10915739 11739529 16109766 11461765 16081117 15619225 10774834 19164858 16485898 18713872 11421492 12594235 17522070 16781746 18071297 17906064
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.0410092053 7440962 6884620 10915739 4309450 2869522 9327722 21278145 17522070 19085960 7179309 16177239 7120509 16227642 3732212 15968718 6623471 11566570 19336974 3786805 15998439 15027814
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 13.0417654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 13.0419107877
MESH:D056486 Drug-Induced Liver Injury Diquat 13.0418445702 18164269
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.0420420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6019426721
MESH:D004362 Drug Toxicity Gentamicins 7.1811033412 15033597
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.1811462148
MESH:D004381 Duodenal Ulcer Ampicillin 8.5710671773
MESH:D004381 Duodenal Ulcer Curcumin 8.5717351913
MESH:D050171 Dyslipidemias Dietary Fats 3.1018367378
MESH:D004421 Dystonia Phenobarbital 3.551851702
MESH:D004487 Edema pirinixic acid 5.1212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.1212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.2918230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.2918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.4112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.4119031437
MESH:D016889 Endometrial Neoplasms Estradiol 10.5218566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 10.5220544844 19155303 17893378 16202921
MESH:D016889 Endometrial Neoplasms Tretinoin 10.5216569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.6010568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.633659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.383922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.6320417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.136401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.787750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.533659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6216302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.1812903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.6111564622
MESH:D005124 Eye Abnormalities Tretinoin 7.6116938888 9664655
MESH:D005234 Fatty Liver arsenic trioxide 41.2615073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 41.2612795759 61145 12631006 15959796 19224547 16239168 16045604 17595544
MESH:D005234 Fatty Liver Curcumin 41.2619297423
MESH:D005234 Fatty Liver Cyclosporine 41.2619224547
MESH:D005234 Fatty Liver Dietary Fats 41.2618296743 17967931 19004024 19551842
MESH:D005234 Fatty Liver Diethylnitrosamine 41.2620387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 41.2615345470
MESH:D005234 Fatty Liver pirinixic acid 41.2620131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 41.2619224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 2.9316709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.9811858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.0414745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.6919069698
MESH:D005355 Fibrosis Carbon Tetrachloride 28.3518705752
MESH:D005355 Fibrosis Curcumin 28.3518705752
MESH:D005355 Fibrosis Cyclosporine 28.3512639820 12168785
MESH:D005355 Fibrosis Dietary Fats 28.3518296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 28.3520067830
MESH:D005355 Fibrosis Tretinoin 28.3517994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8016904648
MESH:D005756 Gastritis Acetaminophen 9.8016983495
MESH:D005756 Gastritis Diquat 9.8015046732
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2218462866
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.738708960
MESH:D005909 Glioblastoma Curcumin 10.1317596214
MESH:D005909 Glioblastoma Fenretinide 10.1316187019
MESH:D005909 Glioblastoma Tretinoin 10.1317312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1010696789
MESH:D006258 Head and Neck Neoplasms Curcumin 6.7718462866 18829502
MESH:D006258 Head and Neck Neoplasms Tretinoin 6.7716096774
MESH:D034381 Hearing Loss Gentamicins 4.4718024279 17868369 19130971 15968427
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6616084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.6210048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 5.6214991402 9664655
MESH:D006331 Heart Diseases Ciprofloxacin 4.3511505790
MESH:D006333 Heart Failure pirinixic acid 2.2320558911
MESH:D016481 Helicobacter Infections Ciprofloxacin 5.0317643012
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9315720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9011000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1419110552 19900420
MESH:D006529 Hepatomegaly Phenobarbital 16.8316109766
MESH:D006529 Hepatomegaly pirinixic acid 16.8319772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly propiconazole 16.8317178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 16.8315340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.5617701891
MESH:D006558 Herpes Genitalis Estradiol 4.5315709030
MESH:D019584 Hot Flashes Estradiol 8.7717088409
MESH:D019584 Hot Flashes Isoflavones 8.7714716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5518606429 8697196 16354765 16959395 15340226
MESH:D006930 Hyperalgesia Acetaminophen 6.3516870215
MESH:D006930 Hyperalgesia Tretinoin 6.3516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0416899240
MESH:D053565 Hypercalciuria Gentamicins 5.2217652376
MESH:D006937 Hypercholesterolemia Curcumin 7.7918704882
MESH:D006937 Hypercholesterolemia Dietary Fats 7.7921332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.0916778211
MESH:D006943 Hyperglycemia pirinixic acid 2.7620558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.1721332399
MESH:D006973 Hypertension Cyclosporine 4.2610903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.2618670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6115338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3316569931 16945680
MESH:D007022 Hypotension Chloramphenicol 5.8610100024
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0112013081
MESH:D007248 Infertility, Male Diquat 6.014850670
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.0117937319
MESH:D007249 Inflammation Curcumin 12.9716956363 18403477 17151092
MESH:D007249 Inflammation Dietary Fats 12.9720412841
MESH:D007249 Inflammation Diethylnitrosamine 12.9718785209
MESH:D007249 Inflammation Tamoxifen 12.9719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 12.9712200463 12878042
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0018596194 18200517
MESH:D007333 Insulin Resistance Dietary Fats 10.3911836018 18457598
MESH:D007333 Insulin Resistance Estradiol 10.3916627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 10.3916306350
MESH:D007410 Intestinal Diseases Tretinoin 3.2917994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.8010783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.4816580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.4815992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9415604871
MESH:D007673 Kidney Cortex Necrosis Gentamicins 5.2318842672
MESH:D007674 Kidney Diseases Acetaminophen 12.0315629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 12.0318776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 12.0315618244
MESH:D007674 Kidney Diseases Gentamicins 12.0319349640 17934191 18289764
MESH:D007680 Kidney Neoplasms Cyclosporine 10.0812371664
MESH:D007680 Kidney Neoplasms Estradiol 10.0815610895
MESH:D007680 Kidney Neoplasms Tamoxifen 10.0818625569
MESH:D007683 Kidney Tubular Necrosis, Acute Gentamicins 4.8811231351
MESH:D007889 Leiomyoma Curcumin 4.1218555241
MESH:D016773 Leishmaniasis, Cutaneous Gentamicins 4.0710219319
MESH:D007938 Leukemia arsenic trioxide 9.0115070760
MESH:D007938 Leukemia Curcumin 9.0118462866
MESH:D007938 Leukemia Tretinoin 9.0117143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.3212560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.3216106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.0614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.0319077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.0316482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.5220471514 16467208 17050201 19850784 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.5219850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.5412018890 16112521 11161223 17712046 15213294 16331271 12679006 19642359 15622746 16823087 19225113 19035177 17869043 15336539 17217047 16330433 16891316 17649720 19075265 12712474 16966277 9834237 17107899 11468182 15748426
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 6.5419075265 17107899 17368321 16823087 16331271 19035177 17301526 16788101 16935935 17649720 17506722 17217047 16891316 17339181 19225113 16140955 15748426 17294898 16766008 19642359 12679006 17712046 19029980 17361223 9834237
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.1716882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.1716106398
MESH:D007970 Leukopenia Ciprofloxacin 5.3117846019
MESH:D007972 Leukoplakia, Oral Fenretinide 5.5516707609
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.959224671
MESH:D008064 Lipidoses Tamoxifen 2.8017567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 13.4111903743 17157831 17174718 11408273 16221502 16943688 16239168 21278145 17334410
MESH:D008103 Liver Cirrhosis Dietary Fats 13.4118296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 13.4118522880 18407596 20032147 19638242 18665156
MESH:D008103 Liver Cirrhosis Phenobarbital 13.4121047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.7112666154 18481824 17481882 17698563 16192424 17640975 18472332 17900296 12632512 18156304 14716496 18420326 17631135 12741479 16638106 12667390 18395914 18395095 15370692 12609069 17922224 12586293 14512876 17525996 18187930 18339082 14748882 12389079 18210741 18317297 12632514 17976157 12546737 16116963 18412020 18418968 13678700 20821823 15730626 16011737 18376398 18166357 17766677 14716833 15338365 18263696 17805973 14620537 16136751 18429990 18251166 15057751 18472094 18054572 12958196 17721639 16248980 17565644 12898905 18279442 15673190 10355542 17761835 15362042 17869086 15893842 17823541 12445418 12649538 16027843 17714472 15959796 17708605 14724832 15818738 15650968 17557913 15925388 15931870 15052691 18277467 15996030 17944888 16015684 15123356 11481614 18205269 16033810 15876570 18705752 16097048 18006644 12445421
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 9.7117355460 18006644 18705752
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 9.7114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.7115474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 9.7118564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.7112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 9.7116248980 18397230
MESH:D008107 Liver Diseases Acetaminophen 13.8912969438 16611625 19014921 16610002 19784758 12587719 11587558 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.8915720792 17285989 15830285 16964402 16246199
MESH:D008107 Liver Diseases Curcumin 13.8916956363
MESH:D008107 Liver Diseases Diethylnitrosamine 13.8917034775
MESH:D008107 Liver Diseases Phenobarbital 13.8919363144
MESH:D008107 Liver Diseases propiconazole 13.8919363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6915123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.0016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.0016899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 22.2714682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 22.2719294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 22.2720452335 21071580 21047994 12771043 19255062 19812893 10737359 19254457 19850985 20137499 19833225 19642983 19090486 18978307 20434301 18648771 19256749 20501860 21167192 15175105 18754104 21278145 19073162 18977376 20405173 19294768 15885732 2862719 2422723 19690152 20583210 20101389 9163691 19499222 19427195 12112319 18644402 20118626 20492335 19551842 19996281 19638242 16942905 19426721
MESH:D008113 Liver Neoplasms Phenobarbital 22.2715975961 19812893 19482888 19073162 21047994 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 22.2716377806 15890375 20007298
MESH:D008113 Liver Neoplasms propiconazole 22.2719028983
MESH:D008113 Liver Neoplasms Tamoxifen 22.2716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 22.2716984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 19.2820377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 19.2812014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 19.2819009564 18308698 19004024 17854601 17174075 3124819 19539802 21159647 16267830 16842330 19519916 18253720 9362446 18164116 18544905 18079962 19126423 17942915 18775883 18282651 2563599 18093689
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 19.2818308698 1399818 2563599 17172636 6150874
MESH:D008114 Liver Neoplasms, Experimental propiconazole 19.2817178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.2812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.9815213294
MESH:D055370 Lung Injury Ciprofloxacin 4.6418197910
MESH:D008175 Lung Neoplasms arsenic trioxide 7.5719825857 11798837
MESH:D008175 Lung Neoplasms Ciprofloxacin 7.5720211752
MESH:D008175 Lung Neoplasms Curcumin 7.5718462866 19359593 16243823
MESH:D008175 Lung Neoplasms Diethylnitrosamine 7.5720512841 20970405 21163286 6695378
MESH:D008175 Lung Neoplasms Tamoxifen 7.5718625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 7.5719555203 11884234
MESH:D008223 Lymphoma Curcumin 3.2418462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.2216173963
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.2819428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 8.2016891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Fenretinide 8.2010697514
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 8.2014580682 19196722 19196723 16827153 11731420
MESH:D020149 Manganese Poisoning Estradiol 10.9919453300
MESH:D020149 Manganese Poisoning Tamoxifen 10.9919453300
MESH:D008527 Medulloblastoma Tretinoin 2.5717453147
MESH:D008545 Melanoma Curcumin 6.4518462866 17885582
MESH:D008545 Melanoma Fenretinide 6.4516270382
MESH:D008545 Melanoma Tamoxifen 6.4519393235 12393984
MESH:D008545 Melanoma Tretinoin 6.4516752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.6915990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.0919513568
MESH:D008569 Memory Disorders Curcumin 3.6917263510
MESH:D008591 Meningomyelocele Tretinoin 3.9516940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2916801185
MESH:D009062 Mouth Neoplasms Fenretinide 3.9416274795
MESH:D009101 Multiple Myeloma arsenic trioxide 6.2714977855 19417148 19549372 11468182 15949261
MESH:D009101 Multiple Myeloma Curcumin 6.2719372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.4317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.0316239165
MESH:D009137 Muscular Dystrophy, Animal Gentamicins 5.7818694830
MESH:D009164 Mycobacterium Infections Ciprofloxacin 10.2310063276
MESH:D009164 Mycobacterium Infections Ofloxacin 10.2318474467
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.1718349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.8116105982 16882451
MESH:D009190 Myelodysplastic Syndromes Ciprofloxacin 10.819809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 10.8117596541
MESH:D009203 Myocardial Infarction pirinixic acid 1.9319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.0016810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.0016411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.9917484760
MESH:D016870 Neisseriaceae Infections Ciprofloxacin 5.8720378725
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.7916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.7918495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.019029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.0119393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3419410462
MESH:D009369 Neoplasms Fenretinide 6.8417353921 15958647
MESH:D009369 Neoplasms pirinixic acid 6.8417405874
MESH:D009369 Neoplasms Tretinoin 6.8416946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.1912497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 9.1919200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.2517289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 2.8719348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 13.6616427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 13.6614600291
MESH:D009421 Nervous System Malformations Tretinoin 13.669125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.1318462866
MESH:D009436 Neural Tube Defects arsenic trioxide 6.2110525206
MESH:D009436 Neural Tube Defects Tretinoin 6.219142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.8618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.8620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6220387270
MESH:D009472 Neuronal Ceroid-Lipofuscinoses Fenretinide 5.1916303764
MESH:D009503 Neutropenia Ciprofloxacin 4.7117846019
MESH:D009765 Obesity Curcumin 6.5819297423
MESH:D009765 Obesity Dietary Fats 6.5817217161 11836018 21332399 18457598 16723640 18674790 20518802 20132043 19632207
MESH:D009765 Obesity pirinixic acid 6.5820558911
MESH:D010018 Osteomalacia Phenobarbital 3.8817016548
MESH:D010024 Osteoporosis Curcumin 6.6318719352
MESH:D010024 Osteoporosis Isoflavones 6.6316562857
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.0916624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Curcumin 13.0918462866 19020741
MESH:D010051 Ovarian Neoplasms Estradiol 13.0919401270
MESH:D010051 Ovarian Neoplasms Fenretinide 13.0916133793
MESH:D010051 Ovarian Neoplasms Tretinoin 13.0916936753
MESH:D010146 Pain Acetaminophen 5.2916870215
MESH:D010146 Pain Tretinoin 5.2916870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 17.9215580305
MESH:D010190 Pancreatic Neoplasms Curcumin 17.9217440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 17.9216540662
MESH:D010190 Pancreatic Neoplasms Fenretinide 17.9215580305
MESH:D010190 Pancreatic Neoplasms Phenobarbital 17.9216965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 17.9215976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2411578682
MESH:D010235 Paraganglioma arsenic trioxide 3.7119927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7512520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1018163543
MESH:D011230 Precancerous Conditions Cyclosporine 12.9012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.902563599
MESH:D011230 Precancerous Conditions Phenobarbital 12.902563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.7111399792 11896295 11118676 11222880
MESH:D011317 Priapism Methylene Blue 6.739542685
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.4520887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8819131511
MESH:D011471 Prostatic Neoplasms Curcumin 1.8818226269 11398177 12497104 18156803 10851300 18769126 15129424
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Fenretinide 1.8817024972
MESH:D011471 Prostatic Neoplasms Isoflavones 1.8817374662 16365062 17219775 17571952
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011507 Proteinuria Gentamicins 8.0515033597
MESH:D011507 Proteinuria Tretinoin 8.0516636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.8316919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.0012752131
MESH:D011565 Psoriasis Cyclosporine 2.0416882103
MESH:D011625 Pterygium Tretinoin 4.3016723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.1019168576
MESH:D012003 Rectal Fistula Ciprofloxacin 5.8718371140
MESH:D051437 Renal Insufficiency Gentamicins 4.5215728788 17132701
MESH:D015427 Reperfusion Injury pirinixic acid 2.1319058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.5810666014 18379247
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.3718990726
MESH:D012162 Retinal Degeneration Fenretinide 4.0316303925
MESH:D012173 Retinitis Gentamicins 5.7818644591
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6516116481 16283617
MESH:D012509 Sarcoma Curcumin 3.6918462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.5016646077
MESH:D012640 Seizures Phenobarbital 2.373137016 16876388 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.336407741
MESH:D018805 Sepsis Curcumin 3.6818389075
MESH:D012852 Sinusitis Ampicillin 6.037327846
MESH:D012878 Skin Neoplasms Fenretinide 8.0916467112
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.0916192470
MESH:D012878 Skin Neoplasms Tretinoin 8.0916467112
MESH:D013088 Spermatocele Ethinyl Estradiol 9.9116709447
MESH:D013088 Spermatocele Tamoxifen 9.9116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.5519457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.0417007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.0418456281
MESH:D013274 Stomach Neoplasms Tretinoin 3.0417261132
MESH:D013276 Stomach Ulcer Curcumin 3.0819188055 16631530
MESH:D024801 Tauopathies Methylene Blue 6.1016930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.1711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4112697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 14.0419014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 14.047505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 14.041399818
MESH:D013964 Thyroid Neoplasms Tretinoin 14.0416026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.1919048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.3616051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.4815213294
MESH:D014123 Toxoplasmosis Ciprofloxacin 5.5220186551
MESH:D014376 Tuberculosis Tretinoin 2.9116040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 13.5712845720 12973940 11780464 20435036
MESH:D001749 Urinary Bladder Neoplasms Ciprofloxacin 13.5710741713 15028437
MESH:D001749 Urinary Bladder Neoplasms Curcumin 13.5718593936
MESH:D001749 Urinary Bladder Neoplasms Fenretinide 13.5716720286
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 13.578653321 16712894 17572228
MESH:D014565 Urogenital Neoplasms Curcumin 4.7818462866
MESH:D014581 Urticaria Acetaminophen 2.5310982225
MESH:D002583 Uterine Cervical Neoplasms Fenretinide 13.6816154183
MESH:D002583 Uterine Cervical Neoplasms indole-3-carbinol 13.6816082211
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 13.6816129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8414692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.1116752155
MESH:D014605 Uveitis Cyclosporine 3.491336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1012125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1014671159 15869587
MESH:D015837 Vestibular Diseases Gentamicins 5.0518776599
MESH:D014820 Vitiligo Tretinoin 3.5916761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7515886252
MESH:D015430 Weight Gain Dietary Fats 3.3316723640
MESH:D009396 Wilms Tumor Tretinoin 3.5616287080
MESH:D014985 Xerophthalmia Cyclosporine 3.9417120751
Pathway ID Pathway Name
KEGG:00480 Glutathione metabolism
KEGG:01100 Metabolic pathways
REACT:474 Metabolism of carbohydrates
KEGG:00030 Pentose phosphate pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00789 antagonist Gadopentetate dimeglumine Contrast Media;Contrast Agents
DB00851 inhibitor Dacarbazine Antineoplastic Agents;Antineoplastic Agents, Alkylating
DB00920 antagonist Ketotifen Antipruritics;Anti-Allergic Agents;Histamine H1 Antagonists
DB02076 - 6-Phosphogluconic Acid
DB02212 - Pyrophosphate 2-
DB03962 - Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate
Drugbank ID Action Drug Name Description
DB00563 inhibitor Methotrexate Antineoplastic Agents;Antirheumatic Agents;Antimetabolites;Enzyme Inhibitors;Folic Acid Antagonists;Dermatologic Agents;Immunosuppressive Agents;Nucleic Acid Synthesis Inhibitors;Abortifacient Agents, Nonsteroidal;Abortifacient Agents;Antimetabolites, Antineoplastic
DB00695 inhibitor Furosemide Diuretics;Sodium Potassium Chloride Symporter Inhibitors
DB00814 inhibitor Meloxicam Antineoplastic Agents;Cyclooxygenase Inhibitors;Antiemetics;Analgesics;Growth Inhibitors;Nonsteroidal Anti-inflammatory Agents (NSAIAs)
DB00867 inhibitor Ritodrine Sympathomimetics;Adrenergic beta-Agonists;Tocolytic Agents;Sympathomimetic
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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