AutismKB 2.0

Annotation Detail for ATP6V1A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ATP6V1A ( ATP6A1,ATP6V1A1,HO68,VA68,VPP2,Vma1 )
Gene Full Name: ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
Band: 3q13.31
Quick LinksEntrez ID:523; OMIM: 607027; Uniprot ID:VATA_HUMAN; ENSEMBL ID: ENSG00000114573; HGNC ID: 851
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04145Phagosome
hsa05120Epithelial cell signaling in Helicobacter pylori infection
hsa04966Collecting duct acid secretion
hsa00190Oxidative phosphorylation
hsa01100Metabolic pathways
hsa05110Vibrio cholerae infection
Pathway IDPathway Name
Signaling by Insulin receptor
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of ATP6V1A mRNAincreases expression 16788091
D000638 Amiodarone Amiodarone affects the expression of ATP6V1A mRNAaffects expression 19483382
C006632 arsenic trioxide arsenic trioxide results in increased expression of ATP6V1A mRNAincreases expression 20458559
D001553 Benzbromarone Benzbromarone affects the expression of ATP6V1A mRNAaffects expression 19483382
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ATP6V1A mRNAdecreases expression 20018196
D002083 Butylated Hydroxyanisole Butylated Hydroxyanisole inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein]decreases expression|decreases reaction 12470298
D002083 Butylated Hydroxyanisole Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of ATP6V1A protein]decreases expression|decreases reaction 12470298
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene inhibits the reaction [TNF protein results in decreased expression of ATP6V1A protein]decreases expression|decreases reaction 12470298
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene inhibits the reaction [Reactive Oxygen Species results in decreased expression of ATP6V1A protein]decreases expression|decreases reaction 12470298
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of ATP6V1A mRNAdecreases expression 15336504
D002994 Clofibrate Clofibrate affects the expression of ATP6V1A mRNAaffects expression 19483382
D016572 Cyclosporine Cyclosporine results in decreased expression of ATP6V1A mRNAdecreases expression 20106945
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of ATP6V1A mRNAincreases expression 15289156
D002117 Calcitriol Calcitriol results in decreased expression of ATP6V1A mRNAdecreases expression 12798352
D004958 Estradiol [Progesterone co-treated with Estradiol] results in increased expression of ATP6V1A mRNAaffects cotreatment|increases expression 17404688
D004958 Estradiol Estradiol results in increased expression of ATP6V1A mRNAincreases expression 15289156
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ATP6V1A mRNAincreases expression 17942748
D005001 Ethionine Ethionine affects the expression of ATP6V1A mRNAaffects expression 19483382
D019833 Genistein Genistein results in increased expression of ATP6V1A mRNAincreases expression 15289156
D008628 Mercury Mercury results in decreased expression of ATP6V1A mRNAdecreases expression 16823088
D009853 Omeprazole Omeprazole affects the expression of ATP6V1A mRNAaffects expression 19483382
D017239 Paclitaxel ATP6V1A protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
C006253 pirinixic acid pirinixic acid results in increased expression of ATP6V1A mRNAincreases expression 16221962
C006253 pirinixic acid pirinixic acid affects the expression of ATP6V1A mRNAaffects expression 19483382
D011374 Progesterone [Progesterone co-treated with Estradiol] results in increased expression of ATP6V1A mRNAaffects cotreatment|increases expression 17404688
D011441 Propylthiouracil Propylthiouracil affects the expression of ATP6V1A mRNAaffects expression 19483382
D017382 Reactive Oxygen Species Butylated Hydroxyanisole inhibits the reaction [Reactive Oxygen Species results in decreased expression of ATP6V1A protein]decreases expression|decreases reaction 12470298
D017382 Reactive Oxygen Species Butylated Hydroxytoluene inhibits the reaction [Reactive Oxygen Species results in decreased expression of ATP6V1A protein]decreases expression|decreases reaction 12470298
D017382 Reactive Oxygen Species Reactive Oxygen Species results in decreased expression of ATP6V1A proteindecreases expression 12470298
C004648 testosterone enanthate testosterone enanthate affects the expression of ATP6V1A mRNAaffects expression 17440010
D013853 Thioacetamide Thioacetamide affects the expression of ATP6V1A mRNAaffects expression 19483382
D014212 Tretinoin Tretinoin results in increased expression of ATP6V1A mRNAincreases expression 16054129
D014501 Uranium Uranium affects the expression of ATP6V1A mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of ATP6V1A mRNAaffects expression 15672453
C025643 vinclozolin vinclozolin affects the expression of ATP6V1A mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6817505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.8818653653
MESH:D000230 Adenocarcinoma arsenic trioxide 9.5911798837 19825857
MESH:D000230 Adenocarcinoma Estradiol 9.5911473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.5914692618
MESH:D000230 Adenocarcinoma Genistein 9.5911473722
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.2216434500
MESH:D000505 Alopecia Tretinoin 3.4115955085
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2315469931
MESH:D001008 Anxiety Disorders vinclozolin 3.4319015723
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.5818218290 18057881 20041841
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.6715885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.6716412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2016292516
MESH:D001249 Asthma Tretinoin 2.2716456186
MESH:D001281 Atrial Fibrillation Amiodarone 3.7118651412 19698954
MESH:D001321 Autistic Disorder Mercury 2.8117497416
MESH:D001327 Autoimmune Diseases Mercury 4.6116634805
MESH:D001471 Barrett Esophagus Tretinoin 4.1516935849
MESH:D001778 Blood Coagulation Disorders Amiodarone 61.1319483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 61.1316206674
MESH:D001778 Blood Coagulation Disorders Benzbromarone 61.1319483382
MESH:D001778 Blood Coagulation Disorders Clofibrate 61.1319483382
MESH:D001778 Blood Coagulation Disorders Ethionine 61.1319483382
MESH:D001778 Blood Coagulation Disorders Omeprazole 61.1319483382
MESH:D001778 Blood Coagulation Disorders pirinixic acid 61.1319483382
MESH:D001778 Blood Coagulation Disorders Propylthiouracil 61.1319483382
MESH:D001778 Blood Coagulation Disorders Thioacetamide 61.1319483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 61.1316206674 16197459
MESH:D001859 Bone Neoplasms Paclitaxel 4.3215867366
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.0717868700
MESH:D001930 Brain Injuries Progesterone 4.0015665606 15380490 15845082
MESH:D001943 Breast Neoplasms Calcitriol 3.5911237771
MESH:D001943 Breast Neoplasms Diethylstilbestrol 3.5917129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 3.5919861407 12948864 17261762 14630087 16675129 17289903 18497071 17018787
MESH:D001943 Breast Neoplasms Genistein 3.5917200150 16541309 16873071
MESH:D001943 Breast Neoplasms Paclitaxel 3.5916244791 16115903 16273361 18234424 15136595 11325840 18223236 18323546
MESH:D001943 Breast Neoplasms Progesterone 3.5916175315 15562024 17614352
MESH:D001943 Breast Neoplasms Tretinoin 3.5916443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.3316813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2016111702
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8916168501
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 16.1416217749 15073043 11135700 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Benzbromarone 16.141701930
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 16.1415948411 16924424
MESH:D006528 Carcinoma, Hepatocellular Estradiol 16.1416924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 16.1416924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 16.1416313753
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 16.1417997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 16.141917145
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6119014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8912490120
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 4.5111237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.5116096774 16051514
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 5.8619225199 15710769
MESH:D002311 Cardiomyopathy, Dilated Mercury 5.8610334427
MESH:D002318 Cardiovascular Diseases Genistein 3.1316332659
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.8218974383
MESH:D002386 Cataract Tretinoin 2.9417460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 14.5720889678
MESH:D002471 Cell Transformation, Neoplastic Clofibrate 14.571399818
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 14.5712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.5718566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3316129372
MESH:D002637 Chest Pain Omeprazole 4.8415447763
MESH:D018281 Cholangiocarcinoma Thioacetamide 4.0718291259
MESH:D002779 Cholestasis Cyclosporine 12.2319486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.2317681005 11677210 17110522 15861022 17333356 16105132 16919318
MESH:D002779 Cholestasis pirinixic acid 12.2319176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8916461808
MESH:D002972 Cleft Palate Tretinoin 2.569407595
MESH:D003092 Colitis Tretinoin 3.4517035595
MESH:D003110 Colonic Neoplasms Genistein 2.2417182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6420501625
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.6418802399
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9312609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.8310525206
MESH:D019465 Craniofacial Abnormalities Reactive Oxygen Species 3.8315736158
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.8316925845 9211117 8800419 9664655 10589399 9224671 17551590 14991402 9142499 9125849
MESH:D003456 Cryptorchidism Diethylstilbestrol 10.5312952375 16002989
MESH:D003456 Cryptorchidism vinclozolin 10.5314966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8515213294
MESH:D017449 Dermatitis, Allergic Contact Mercury 3.5516823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.4216647724
MESH:D003928 Diabetic Nephropathies Estradiol 3.1919279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.2317187935
MESH:D056486 Drug-Induced Liver Injury Amiodarone 4.0115265979 18218290
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 4.0112963478
MESH:D004381 Duodenal Ulcer Omeprazole 4.0817151854 21218061 16613094 15991576
MESH:D050171 Dyslipidemias Clofibrate 3.8816707586
MESH:D004487 Edema pirinixic acid 2.2612083418
MESH:D004489 Edema, Cardiac Tretinoin 4.2018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 13.9215138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.9212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 13.9217692515
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.0116402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.0116402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 16.4016804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 16.4019148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 16.4011473722
MESH:D016889 Endometrial Neoplasms Tretinoin 16.4016569247
MESH:D004715 Endometriosis Progesterone 3.5416134523
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.9120426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.9112903497
MESH:D004938 Esophageal Neoplasms Paclitaxel 6.9116481741
MESH:D005124 Eye Abnormalities Tretinoin 3.3816938888 9664655
MESH:D005218 Fat Necrosis Thioacetamide 5.4516456712
MESH:D005234 Fatty Liver Amiodarone 27.6614986274
MESH:D005234 Fatty Liver arsenic trioxide 27.6615073043
MESH:D005234 Fatty Liver Clofibrate 27.6619224547
MESH:D005234 Fatty Liver Cyclosporine 27.6619224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 27.6615345470
MESH:D005234 Fatty Liver pirinixic acid 27.6619236843 20131406
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.5016513791 16611131 16534752 16002989 15751030
MESH:D005355 Fibrosis Cyclosporine 7.8312168785 12639820
MESH:D005355 Fibrosis Tretinoin 7.8317994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0116904648
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.6716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.0316417039
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.6816452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.958708960
MESH:D005909 Glioblastoma Genistein 6.6516598420
MESH:D005909 Glioblastoma Tretinoin 6.6517312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.0116096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8916084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.7614991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.3820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.1615720958
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.3418665440 17276928 15929193
MESH:D006505 Hepatitis Thioacetamide 3.9716456712
MESH:D006529 Hepatomegaly Amiodarone 7.7215265979
MESH:D006529 Hepatomegaly pirinixic acid 7.7218467677 16221962 19772884 19176532
MESH:D006558 Herpes Genitalis Estradiol 4.7615709030
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.4817440010
MESH:D019584 Hot Flashes Estradiol 3.4917088409
MESH:D006930 Hyperalgesia Tretinoin 3.0116870215
MESH:D006937 Hypercholesterolemia Amiodarone 3.648137927 9751232
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.3116778211
MESH:D006943 Hyperglycemia pirinixic acid 2.9620558911
MESH:D006965 Hyperplasia Diethylstilbestrol 4.1812960047 14722030
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 4.2817604070
MESH:D006973 Hypertension Cyclosporine 2.0010903974
MESH:D007021 Hypospadias Diethylstilbestrol 10.3816002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.3816945680 16569931
MESH:D007037 Hypothyroidism Amiodarone 10.7517991464 18020914
MESH:D007037 Hypothyroidism Propylthiouracil 10.758137927 18031379
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.1415869954
MESH:D007246 Infertility Diethylstilbestrol 4.1015036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.0917937319
MESH:D007248 Infertility, Male vinclozolin 6.0916467254
MESH:D007249 Inflammation Progesterone 2.4715869954
MESH:D007333 Insulin Resistance Estradiol 6.6316627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 6.6316306350
MESH:D007410 Intestinal Diseases Tretinoin 3.5117994277
MESH:D002532 Intracranial Aneurysm Reactive Oxygen Species 4.7419381132
MESH:D007569 Jaw Abnormalities Tretinoin 3.6617551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1715604871
MESH:D007674 Kidney Diseases Cyclosporine 9.2818776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 9.2815618244
MESH:D007674 Kidney Diseases Mercury 9.2817934191
MESH:D007680 Kidney Neoplasms Cyclosporine 11.2112371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 11.2115003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 11.2115610895
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8117184923
MESH:D016773 Leishmaniasis, Cutaneous Omeprazole 3.8919248655
MESH:D007938 Leukemia arsenic trioxide 9.7415070760
MESH:D007938 Leukemia Genistein 9.7417468513 18980019
MESH:D007938 Leukemia Tretinoin 9.7417143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5612560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2414633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.6919077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.6916932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.7119850784 16968895 20471514 16467208 17050201
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.7119850784 17596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.0719075265 17217047 12712474 17869043 11468182 15213294 17107899 17649720 17712046 19225113 19642359 16823087 16331271 15622746 16112521 12679006 15748426 12018890 15336539 11161223 16330433 16891316 19035177 16966277 9834237
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.0717368321 19035177 19225113 17217047 16331271 16766008 17301526 16140955 12679006 9834237 19075265 17361223 17506722 16891316 16935935 17107899 15748426 17712046 16788101 17649720 19029980 19642359 16823087 17294898 17339181
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1016882451
MESH:D007984 Leydig Cell Tumor vinclozolin 4.4716417039
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.129224671
MESH:D008064 Lipidoses Amiodarone 3.3217567588 15342952
MESH:D008080 Liposarcoma Paclitaxel 4.5817353645
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.3714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 6.3717823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.3715474484
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 6.3716248980 15288473 17355460 16098781 12175628 12891558 16343077 12679928 17629604 16097051 15288472 17050028 18031379 16489207 18380797 10677585 17292413 18263696 15158331 15465738 18458672 17127702 15716488 12085344 18295389 18615449 15362042 12557150 15474484 16511523 11172339 18606216 18395095 14739098 16126171 15334695 15095483 18416461 15078482 11682029 15075984 15316131 12531686 18032466 11481614
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.3716248980 18397230
MESH:D008107 Liver Diseases Thioacetamide 2.6415158337 18374380 16337175
MESH:D017114 Liver Failure, Acute Thioacetamide 4.0815633222 15313186 12479984 17276928
MESH:D008113 Liver Neoplasms arsenic trioxide 9.9314682389
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 9.9318177683
MESH:D008113 Liver Neoplasms Diethylstilbestrol 9.9315890375 16712894
MESH:D008113 Liver Neoplasms pirinixic acid 9.9316377806 20007298 15890375
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.5820377131
MESH:D008133 Long QT Syndrome Amiodarone 7.5415350150 11989578 17391786
MESH:D008133 Long QT Syndrome arsenic trioxide 7.5415213294
MESH:D008171 Lung Diseases Amiodarone 3.2012587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.2118516814
MESH:D008175 Lung Neoplasms arsenic trioxide 2.8119825857 11798837
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 2.8119925653 11696405 11246140 16337739 18597497 15390079 19359593
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8915166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.2915700306
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.8814749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.2516002989
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 12.961500032
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 12.9617203775 11408345 16891317 11807958
MESH:D008325 Mammary Neoplasms, Experimental Genistein 12.9612929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 12.9611408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.2219453300
MESH:D008527 Medulloblastoma Tretinoin 2.6817453147
MESH:D008545 Melanoma Paclitaxel 5.0612025231 16342250 12040289
MESH:D008545 Melanoma Reactive Oxygen Species 5.0617992120
MESH:D008545 Melanoma Tretinoin 5.0616752155
MESH:D008591 Meningomyelocele Tretinoin 4.1716940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5216801185
MESH:D009101 Multiple Myeloma arsenic trioxide 6.8911468182 15949261 14977855 19549372 19417148
MESH:D009101 Multiple Myeloma Paclitaxel 6.8914749477
MESH:D009135 Muscular Diseases pirinixic acid 3.2516239165
MESH:D009181 Mycoses Amiodarone 4.6312754197 17974566
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.8916882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.8917596541
MESH:D009203 Myocardial Infarction Genistein 5.3117141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.3119151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 13.0216810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 13.0217141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 13.0216411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7116624393
MESH:D009362 Neoplasm Metastasis Paclitaxel 3.1515867366
MESH:D009369 Neoplasms Diethylstilbestrol 7.5115313581
MESH:D009369 Neoplasms pirinixic acid 7.5117405874
MESH:D009369 Neoplasms Tretinoin 7.5116594593 16946489
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0619348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 21.4211399458
MESH:D009421 Nervous System Malformations Estradiol 21.4216427766 11399458
MESH:D009421 Nervous System Malformations Genistein 21.4216427766
MESH:D009421 Nervous System Malformations Tretinoin 21.429125849
MESH:D009436 Neural Tube Defects arsenic trioxide 6.7410525206
MESH:D009436 Neural Tube Defects Tretinoin 6.749142499
MESH:D052556 Niemann-Pick Disease, Type C Clofibrate 4.689802331
MESH:D009765 Obesity pirinixic acid 1.7520558911
MESH:D010014 Osteolysis Paclitaxel 4.7215867366
MESH:D010024 Osteoporosis Genistein 3.0919401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.8416169203
MESH:D010051 Ovarian Neoplasms arsenic trioxide 17.7616624393 12452020 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 17.7619401270
MESH:D010051 Ovarian Neoplasms Genistein 17.7619005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 17.7611161223
MESH:D010051 Ovarian Neoplasms Progesterone 17.7616525653 17393432
MESH:D010051 Ovarian Neoplasms Tretinoin 17.7616936753
MESH:D010146 Pain Tretinoin 2.7016870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.2215580305
MESH:D010190 Pancreatic Neoplasms Reactive Oxygen Species 8.2215580305
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.2215976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4411578682
MESH:D010235 Paraganglioma arsenic trioxide 3.9219927285
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.9014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.4115687265 16977796
MESH:D011014 Pneumonia Butylated Hydroxytoluene 4.9011893704
MESH:D011230 Precancerous Conditions Cyclosporine 3.0012371664
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 8.9517184923
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 8.9519015723 18042343 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.6718220299
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.5215572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.6520887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8819131511
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8815754350 12479363 18247401 16644109 16289102
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 1.8815846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Genistein 1.8816925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Paclitaxel 1.8817172428 16729912 16356831 17136230
MESH:D011472 Prostatitis vinclozolin 4.6718629315
MESH:D011507 Proteinuria Tretinoin 3.3616636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.0515861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1416882103
MESH:D011625 Pterygium Tretinoin 4.5316723453
MESH:D011658 Pulmonary Fibrosis Amiodarone 2.7512490602 12832656 11597910
MESH:D015427 Reperfusion Injury pirinixic acid 2.2619058328
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8616283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7618045962
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.7116646077
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.8218724381
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.398532709
MESH:D012878 Skin Neoplasms Tretinoin 5.3916467112
MESH:D013088 Spermatocele Diethylstilbestrol 10.8216002989 16709447
MESH:D013088 Spermatocele Ethinyl Estradiol 10.8216709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.0215862959 16503802
MESH:D013272 Stomach Diseases Omeprazole 4.3518545984
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.6017007042
MESH:D013274 Stomach Neoplasms Butylated Hydroxyanisole 4.601399818 3581430
MESH:D013274 Stomach Neoplasms Paclitaxel 4.6018396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 4.6017261132
MESH:D013276 Stomach Ulcer Amiodarone 6.8018087811
MESH:D013276 Stomach Ulcer Omeprazole 6.8010750652 15991576 18237397 17977527 16755016 11906479
MESH:D013610 Tachycardia Amiodarone 4.0411238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.9419225199
MESH:D024801 Tauopathies Paclitaxel 4.5516930453
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9315669648
MESH:D013959 Thyroid Diseases Amiodarone 4.4919731979
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.9319014326
MESH:D013964 Thyroid Neoplasms Propylthiouracil 10.9315710170
MESH:D013964 Thyroid Neoplasms Tretinoin 10.9316026305 17045167
MESH:D013971 Thyrotoxicosis Amiodarone 4.6019584973 18020914
MESH:D013978 Tibial Fractures Estradiol 4.4219048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.5616051514
MESH:D016171 Torsades de Pointes Amiodarone 9.3811989578 17467628
MESH:D016171 Torsades de Pointes arsenic trioxide 9.3815213294
MESH:D014376 Tuberculosis Tretinoin 3.0716040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 7.9812845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Butylated Hydroxyanisole 7.981399818
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 7.9816452187 16712894 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 8.7516175088
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.7516129372
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.9014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.6416690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.6414692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.3416752155
MESH:D014605 Uveitis Cyclosporine 3.721336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1816513791 16002989
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3015869587 14671159
MESH:D014820 Vitiligo Tretinoin 3.8116761959
MESH:D009396 Wilms Tumor Tretinoin 3.7516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.1717120751
Pathway ID Pathway Name
KEGG:04966 Collecting duct acid secretion
KEGG:05120 Epithelial cell signaling in Helicobacter pylori infection
KEGG:01100 Metabolic pathways
KEGG:00190 Oxidative phosphorylation
KEGG:04145 Phagosome
KEGG:05323 Rheumatoid arthritis
REACT:498 Signaling by Insulin receptor
REACT:15518 Transmembrane transport of small molecules
KEGG:05110 Vibrio cholerae infection
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25152
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00630 antagonist Fosavance Antihypocalcemic Agents;Bisphosphonates;Antiresorptives;Bone Density Conservation Agents
    DB01077 antagonist Didrocal Antineoplastic Agents;Antihypocalcemic Agents;Bisphosphonates;Osteoporosis Prophylactic;Bone Density Conservation Agents
    DB01133 antagonist Tiludronate Antihypocalcemic Agents;Osteoporosis Prophylactic;Bone Density Conservation Agents
    DB06733 antagonist Bafilomycin A1
    DB06734 antagonist Bafilomycin B1
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved