Annotation Detail for SERPINB9
Basic Information Top
| Gene Symbol: | SERPINB9 ( CAP-3,CAP3,PI9 ) |
|---|---|
| Gene Full Name: | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| Band: | 6p25.2 |
| Quick Links | Entrez ID:5272; OMIM: 601799; Uniprot ID:SPB9_HUMAN; ENSEMBL ID: ENSG00000170542; HGNC ID: 8955 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen results in increased expression of SERPINB9 mRNA | increases expression | 17237823 14617632 |
| C016601 | 4-hydroxytamoxifen | ESR1 protein promotes the reaction [4-hydroxytamoxifen results in increased expression of SERPINB9 mRNA] | increases expression|increases reaction | 17237823 |
| C002202 | 4-oxoretinoic acid | 4-oxoretinoic acid results in decreased expression of SERPINB9 mRNA | decreases expression | 15982314 |
| C103303 | alitretinoin | alitretinoin results in decreased expression of SERPINB9 mRNA | decreases expression | 15982314 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of SERPINB9 mRNA | increases expression | 20106945 |
| C006780 | bisphenol A | bisphenol A results in increased expression of SERPINB9 mRNA | increases expression | 12075121 |
| D002090 | Butyrophenones | Butyrophenones inhibits the reaction [[Estradiol results in increased activity of ESR1 protein] which results in increased expression of SERPINB9 mRNA] | decreases reaction|increases activity|increases expression | 21041310 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of SERPINB9 mRNA | affects expression | 17484886 |
| D003513 | Cycloheximide | Cycloheximide promotes the reaction [moxestrol results in increased expression of SERPINB9 mRNA] | increases expression|increases reaction | 10681578 |
| D016572 | Cyclosporine | Cyclosporine results in decreased expression of SERPINB9 mRNA | decreases expression | 20106945 |
| D002117 | Calcitriol | Calcitriol results in increased expression of SERPINB9 mRNA | increases expression | 16002434 |
| D004958 | Estradiol | Butyrophenones inhibits the reaction [[Estradiol results in increased activity of ESR1 protein] which results in increased expression of SERPINB9 mRNA] | decreases reaction|increases activity|increases expression | 21041310 |
| D004958 | Estradiol | ESR1 protein promotes the reaction [Estradiol results in increased expression of SERPINB9 mRNA] | increases expression|increases reaction | 17237823 |
| D004958 | Estradiol | Estradiol promotes the reaction [ESR1 protein binds to SERPINB9 protein] | affects binding|increases reaction | 14617632 |
| D004958 | Estradiol | [Estradiol results in increased activity of ESR1 protein] which results in increased expression of SERPINB9 mRNA | increases activity|increases expression | 21041310 |
| D004958 | Estradiol | Estradiol results in increased expression of SERPINB9 mRNA | increases expression | 17237823 10681578 |
| D004958 | Estradiol | Estradiol results in increased expression of SERPINB9 protein | increases expression | 17237823 |
| D004958 | Estradiol | fulvestrant inhibits the reaction [Estradiol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 17237823 |
| D004958 | Estradiol | Raloxifene inhibits the reaction [Estradiol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 17237823 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of SERPINB9 mRNA | increases expression | 12075121 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Estradiol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 17237823 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 10681578 |
| D019833 | Genistein | Genistein results in increased expression of SERPINB9 mRNA | increases expression | 12075121 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of SERPINB9 mRNA | increases expression | 12177049 |
| D008070 | Lipopolysaccharides | Lipopolysaccharides results in increased expression of SERPINB9 protein | increases expression | 12177049 |
| C011310 | moxestrol | Cycloheximide promotes the reaction [moxestrol results in increased expression of SERPINB9 mRNA] | increases expression|increases reaction | 10681578 |
| C011310 | moxestrol | fulvestrant inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 10681578 |
| C011310 | moxestrol | IL1B protein inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 12177049 |
| C011310 | moxestrol | moxestrol promotes the reaction [ESR1 protein binds to SERPINB9 protein] | affects binding|increases reaction | 14617632 |
| C011310 | moxestrol | moxestrol results in increased expression of SERPINB9 mRNA | increases expression | 14617632 10681578 12177049 |
| C011310 | moxestrol | moxestrol results in increased expression of SERPINB9 protein | increases expression | 10681578 |
| C011310 | moxestrol | Tamoxifen analog inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 10681578 |
| D011794 | Quercetin | Quercetin results in increased expression of SERPINB9 mRNA | increases expression | 15309432 |
| D020849 | Raloxifene | [Raloxifene binds to ESR1 protein] which binds to SERPINB9 protein | affects binding | 14617632 |
| D020849 | Raloxifene | Raloxifene inhibits the reaction [Estradiol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 17237823 |
| D015474 | Isotretinoin | Isotretinoin results in decreased expression of SERPINB9 mRNA | decreases expression | 15982314 |
| D013629 | Tamoxifen | Tamoxifen analog inhibits the reaction [moxestrol results in increased expression of SERPINB9 mRNA] | decreases reaction|increases expression | 10681578 |
| D013629 | Tamoxifen | Tamoxifen analog results in increased expression of SERPINB9 mRNA | increases expression | 10681578 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 mRNA | increases expression | 12177049 |
| D013755 | Tetradecanoylphorbol Acetate | Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 protein | increases expression | 12177049 |
| D014212 | Tretinoin | Tretinoin metabolite results in decreased expression of SERPINB9 mRNA | decreases expression | 15982314 |
| C025643 | vinclozolin | vinclozolin affects the expression of SERPINB9 mRNA | affects expression | 19015723 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000008 | Abdominal Neoplasms | Tamoxifen | 4.40 | 14745880 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Isotretinoin | 4.39 | 18769834 | |
| MESH:D000015 | Abnormalities, Multiple | Isotretinoin | 4.84 | 18769834 | |
| MESH:D017486 | Acneiform Eruptions | Isotretinoin | 6.13 | 16232082 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 11.49 | 17505938 | |
| MESH:D000152 | Acne Vulgaris | Isotretinoin | 11.49 | 18769834 16185265 | |
| MESH:D055371 | Acute Lung Injury | Lipopolysaccharides | 3.89 | 18653653 11850527 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 9.84 | 20127859 20464547 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 9.84 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 9.84 | 14692618 | |
| MESH:D000230 | Adenocarcinoma | Genistein | 9.84 | 11473722 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.57 | 6695378 | |
| MESH:D000419 | Albuminuria | Raloxifene | 4.45 | 17308373 17451421 | |
| MESH:D000505 | Alopecia | Tretinoin | 3.49 | 15955085 | |
| MESH:D000544 | Alzheimer Disease | Raloxifene | 2.51 | 15800139 | |
| MESH:D000743 | Anemia, Hemolytic | Quercetin | 4.10 | 17084956 | |
| MESH:D001008 | Anxiety Disorders | vinclozolin | 3.52 | 19015723 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 3.92 | 19183758 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 3.31 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 6.90 | 15885639 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 6.90 | 16412693 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 2.23 | 16292516 | |
| MESH:D001249 | Asthma | Tretinoin | 2.30 | 16456186 | |
| MESH:D001260 | Ataxia Telangiectasia | Quercetin | 4.82 | 15336622 | |
| MESH:D001284 | Atrophy | fulvestrant | 4.70 | 11514358 | |
| MESH:D001327 | Autoimmune Diseases | Quercetin | 4.26 | 19761891 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 4.25 | 16935849 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 3.47 | 16197459 16206674 | |
| MESH:D001862 | Bone Resorption | bisphenol A | 3.72 | 11985600 | |
| MESH:D001930 | Brain Injuries | Raloxifene | 4.32 | 16580743 | |
| MESH:D001943 | Breast Neoplasms | alitretinoin | 8.16 | 16344269 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 8.16 | 17474063 20146248 | |
| MESH:D001943 | Breast Neoplasms | bisphenol A | 8.16 | 17123778 | |
| MESH:D001943 | Breast Neoplasms | Calcitriol | 8.16 | 11237771 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 8.16 | 12948864 17289903 16675129 14630087 17018787 17261762 18497071 19861407 | |
| MESH:D001943 | Breast Neoplasms | fulvestrant | 8.16 | 18984771 | |
| MESH:D001943 | Breast Neoplasms | Genistein | 8.16 | 16541309 16873071 17200150 | |
| MESH:D001943 | Breast Neoplasms | Quercetin | 8.16 | 18628248 | |
| MESH:D001943 | Breast Neoplasms | Raloxifene | 8.16 | 17242785 15775269 16912660 17261762 17595753 15758505 16837676 17893378 15572757 17440819 17952589 17049068 | |
| MESH:D001943 | Breast Neoplasms | Tamoxifen | 8.16 | 20065188 19221464 17049068 15565566 18984771 17440819 18997820 15668708 16202921 18629630 19059307 19200415 19289846 19155303 19103187 19084267 17242785 18815881 16818667 20859285 19244106 21152245 19487384 19011961 18425577 20390343 19142967 11161223 19066611 17893378 19410462 17261762 18821012 20135344 16273361 19115204 16873071 19288272 21138602 19189212 20005174 20544844 18855134 19189210 18351453 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 8.16 | 16166294 16443354 16873071 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 4.44 | 16813970 | |
| MESH:D002105 | Cadmium Poisoning | Quercetin | 5.39 | 16962696 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 4.31 | 16111702 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 3.63 | 16097048 3786805 18705752 15700767 16192424 15673190 16050911 10355542 16011737 16227642 16124888 15721981 | |
| MESH:D018270 | Carcinoma, Ductal, Breast | Tamoxifen | 4.35 | 19066611 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 5.01 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 11.07 | 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 11.07 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Genistein | 11.07 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Quercetin | 11.07 | 19519916 12508355 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tamoxifen | 11.07 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 11.07 | 1917145 | |
| MESH:D002278 | Carcinoma in Situ | bisphenol A | 4.84 | 17123778 | |
| MESH:D021441 | Carcinoma, Pancreatic Ductal | Quercetin | 4.80 | 17234771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 13.89 | 20419170 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Calcitriol | 13.89 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Isotretinoin | 13.89 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tetradecanoylphorbol Acetate | 13.89 | 18922899 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 13.89 | 16096774 16051514 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Raloxifene | 9.05 | 17572228 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Tamoxifen | 9.05 | 17572228 | |
| MESH:D006332 | Cardiomegaly | Quercetin | 3.24 | 19794523 | |
| MESH:D002318 | Cardiovascular Diseases | Genistein | 7.16 | 16332659 | |
| MESH:D002318 | Cardiovascular Diseases | Raloxifene | 7.16 | 15775269 | |
| MESH:D002386 | Cataract | Tretinoin | 3.01 | 17460283 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 6.23 | 12371664 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 6.23 | 18566989 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 4.44 | 16129372 | |
| MESH:D054506 | Chloracne | marker/mechanism | 17101203 | ||
| MESH:D002779 | Cholestasis | Cyclosporine | 7.40 | 19486331 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 7.40 | 15861022 17681005 17333356 11677210 17110522 16919318 16105132 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 5.01 | 16461808 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 2.61 | 9407595 | |
| MESH:D003072 | Cognition Disorders | Raloxifene | 4.47 | 15800139 | |
| MESH:D003092 | Colitis | Tretinoin | 3.55 | 17035595 | |
| MESH:D003110 | Colonic Neoplasms | Genistein | 3.82 | 17182828 | |
| MESH:D003110 | Colonic Neoplasms | Quercetin | 3.82 | 17148506 17191121 15741050 19056647 19440933 16640504 11134977 | |
| MESH:D015179 | Colorectal Neoplasms | Quercetin | 2.18 | 18852136 18095365 | |
| MESH:D019465 | Craniofacial Abnormalities | Isotretinoin | 3.02 | 18769834 9879862 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 3.02 | 9224671 8800419 16925845 9125849 9211117 9142499 17551590 10589399 14991402 9664655 | |
| MESH:D003456 | Cryptorchidism | vinclozolin | 4.19 | 14966744 | |
| MESH:D003711 | Demyelinating Diseases | Tamoxifen | 4.21 | 19031437 | |
| MESH:D003865 | Depressive Disorder, Major | Raloxifene | 4.03 | 17474826 | |
| MESH:D003921 | Diabetes Mellitus, Experimental | Quercetin | 3.61 | 19496084 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Genistein | 2.45 | 16647724 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 14.27 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | Raloxifene | 14.27 | 17308373 17451421 15920148 | |
| MESH:D003928 | Diabetic Nephropathies | Tamoxifen | 14.27 | 19279558 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 2.00 | 10092053 16177239 7179309 10915739 6884620 7440962 15027814 3786805 2869522 7120509 17522070 21278145 11566570 15998439 16227642 9327722 19085960 15968718 19336974 6623471 4309450 3732212 | |
| MESH:D004487 | Edema | Raloxifene | 6.85 | 15860553 | |
| MESH:D004487 | Edema | Tetradecanoylphorbol Acetate | 6.85 | 8273558 8113982 11698051 16716910 15177302 7812673 9599246 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 4.32 | 18230668 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Calcitriol | 20.72 | 15138306 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 20.72 | 12538720 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Raloxifene | 20.72 | 15845917 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Tamoxifen | 20.72 | 19031437 | |
| MESH:D004714 | Endometrial Hyperplasia | Genistein | 4.44 | 16402032 | |
| MESH:D016889 | Endometrial Neoplasms | 4-hydroxytamoxifen | 22.31 | 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 22.31 | 18566989 19148513 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Genistein | 22.31 | 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Tamoxifen | 22.31 | 19155303 16202921 20544844 17893378 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 22.31 | 16569247 | |
| MESH:D019446 | Endotoxemia | Lipopolysaccharides | 4.24 | 15821434 17637181 15328337 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 1.97 | 16530937 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 3.46 | 9664655 16938888 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 23.17 | 19224547 15959796 61145 12795759 12631006 17595544 16239168 16045604 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 23.17 | 19224547 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 23.17 | 15345470 | |
| MESH:D005234 | Fatty Liver | Raloxifene | 23.17 | 17473493 | |
| MESH:D005234 | Fatty Liver | Tamoxifen | 23.17 | 14986274 19224547 | |
| MESH:D052776 | Female Urogenital Diseases | Tamoxifen | 3.14 | 16709447 | |
| MESH:D005334 | Fever | Lipopolysaccharides | 3.88 | 9205823 11852909 | |
| MESH:D018221 | Fibromatosis, Abdominal | Tamoxifen | 4.38 | 14745880 | |
| MESH:D018222 | Fibromatosis, Aggressive | Tamoxifen | 4.03 | 19069698 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 19.94 | 18705752 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 19.94 | 12639820 12168785 | |
| MESH:D005355 | Fibrosis | Quercetin | 19.94 | 19474275 | |
| MESH:D005355 | Fibrosis | Tretinoin | 19.94 | 17994277 | |
| MESH:D030342 | Genetic Diseases, Inborn | vinclozolin | 4.78 | 16973722 | |
| MESH:D005832 | Genital Diseases, Male | vinclozolin | 5.15 | 16417039 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 4.07 | 8708960 | |
| MESH:D005909 | Glioblastoma | Genistein | 11.37 | 16598420 | |
| MESH:D005909 | Glioblastoma | Quercetin | 11.37 | 19804834 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 11.37 | 17312396 | |
| MESH:D005910 | Glioma | Quercetin | 3.00 | 17643826 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 3.08 | 16096774 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 5.01 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 6.39 | 20471113 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 6.39 | 14991402 9664655 | |
| MESH:D006331 | Heart Diseases | Raloxifene | 3.43 | 11110106 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 4.27 | 15720958 | |
| MESH:D006463 | Hemolytic-Uremic Syndrome | Lipopolysaccharides | 4.25 | 16366002 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 3.45 | 19900420 19110552 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.88 | 15709030 | |
| MESH:D019584 | Hot Flashes | Estradiol | 3.60 | 17088409 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 3.09 | 16870215 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 4.38 | 16899240 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 4.42 | 16778211 | |
| MESH:D006943 | Hyperglycemia | Quercetin | 3.90 | 18262572 11834736 | |
| MESH:D006973 | Hypertension | Cyclosporine | 8.37 | 10903974 | |
| MESH:D006973 | Hypertension | Quercetin | 8.37 | 18356687 | |
| MESH:D006973 | Hypertension | Raloxifene | 8.37 | 15787275 17577099 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 3.94 | 15338365 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 3.66 | 16569931 16945680 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 3.32 | 12013081 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 10.73 | 17937319 | |
| MESH:D007248 | Infertility, Male | fulvestrant | 10.73 | 11514358 | |
| MESH:D007248 | Infertility, Male | vinclozolin | 10.73 | 16467254 | |
| MESH:D007249 | Inflammation | Lipopolysaccharides | 8.05 | 12878042 17255318 9205823 17963957 17237260 | |
| MESH:D007249 | Inflammation | Tamoxifen | 8.05 | 19457130 | |
| MESH:D007249 | Inflammation | Tetradecanoylphorbol Acetate | 8.05 | 8273558 7562506 15177302 11698051 7812673 | |
| MESH:D007251 | Influenza, Human | Quercetin | 4.36 | 16624496 | |
| MESH:D007333 | Insulin Resistance | bisphenol A | 7.11 | 16393666 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 7.11 | 16393666 16627594 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 3.62 | 17994277 | |
| MESH:D019189 | Iron Metabolism Disorders | Lipopolysaccharides | 4.49 | 17255318 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 3.76 | 17551590 15992940 | |
| MESH:D007627 | Keloid | Quercetin | 4.80 | 17086741 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 4.29 | 15604871 | |
| MESH:D017492 | Keratosis, Seborrheic | alitretinoin | 5.49 | 16144296 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 9.59 | 8314463 10903974 18776723 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 9.59 | 15618244 | |
| MESH:D007674 | Kidney Diseases | Quercetin | 9.59 | 16962696 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 11.65 | 12371664 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 11.65 | 15610895 | |
| MESH:D007680 | Kidney Neoplasms | Tamoxifen | 11.65 | 18625569 | |
| MESH:D007889 | Leiomyoma | Raloxifene | 4.35 | 16973256 | |
| MESH:D007938 | Leukemia | Genistein | 10.11 | 17468513 18980019 | |
| MESH:D007938 | Leukemia | Quercetin | 10.11 | 17468513 | |
| MESH:D007938 | Leukemia | Tretinoin | 10.11 | 17143497 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 3.56 | 16482212 19285840 16932348 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 2.05 | 16294345 19850784 17596541 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 3.05 | 19642359 16891316 16331271 17361223 19029980 16788101 17107899 17506722 16935935 17294898 15748426 16823087 17712046 17301526 17217047 19075265 17339181 17649720 17368321 19035177 16766008 9834237 16140955 12679006 19225113 | |
| MESH:D007970 | Leukopenia | Lipopolysaccharides | 4.55 | 15821434 | |
| MESH:D007984 | Leydig Cell Tumor | vinclozolin | 4.58 | 16417039 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 3.20 | 9224671 | |
| MESH:D008064 | Lipidoses | Tamoxifen | 3.05 | 17567588 15342952 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 2.73 | 21278145 11903743 16239168 17334410 16221502 17174718 16943688 17157831 11408273 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 10.64 | 15338365 20821823 12649538 18187930 12445418 15057751 18472332 18705752 16248980 12898905 16136751 17708605 18472094 18251166 18006644 15362042 15370692 18420326 15730626 11481614 12546737 17640975 16638106 12445421 18395914 16011737 14512876 12741479 15931870 15876570 15650968 12958196 17823541 12586293 12389079 17976157 14620537 18418968 14748882 16192424 18412020 17525996 16015684 18156304 16116963 17944888 15893842 12667390 18210741 17766677 18277467 18429990 17565644 18481824 15052691 15959796 15925388 16027843 18054572 18339082 17481882 17631135 17698563 15673190 14716496 14724832 18317297 18263696 17922224 17714472 17805973 18166357 17869086 17557913 12666154 17761835 10355542 17721639 15996030 12632514 16033810 18279442 17900296 14716833 15818738 16097048 15123356 18376398 12609069 12632512 18395095 18205269 13678700 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 10.64 | 14659978 14716833 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Genistein | 10.64 | 17823541 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Lipopolysaccharides | 10.64 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Quercetin | 10.64 | 12741479 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tamoxifen | 10.64 | 18564211 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 10.64 | 18397230 16248980 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 2.05 | 16246199 15830285 15720792 16964402 17285989 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.01 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 3.56 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 10.25 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 10.25 | 19294768 | |
| MESH:D008113 | Liver Neoplasms | Quercetin | 10.25 | 18980244 | |
| MESH:D008113 | Liver Neoplasms | Tamoxifen | 10.25 | 16684651 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 5.80 | 15583823 12014681 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Quercetin | 5.80 | 19519916 | |
| MESH:D055370 | Lung Injury | Lipopolysaccharides | 3.86 | 21114838 | |
| MESH:D008175 | Lung Neoplasms | alitretinoin | 8.33 | 16413115 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 8.33 | 17053015 20869020 18520028 20464547 20135361 6695378 18569708 18816296 20064080 | |
| MESH:D008175 | Lung Neoplasms | Isotretinoin | 8.33 | 15899809 | |
| MESH:D008175 | Lung Neoplasms | Quercetin | 8.33 | 16280456 | |
| MESH:D008175 | Lung Neoplasms | Tamoxifen | 8.33 | 18625569 | |
| MESH:D008175 | Lung Neoplasms | Tetradecanoylphorbol Acetate | 8.33 | 11807781 | |
| MESH:D015674 | Mammary Neoplasms, Animal | Tamoxifen | 3.61 | 19428831 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 13.51 | 11408345 16891317 17203775 11807958 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Genistein | 13.51 | 12929590 14578162 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tamoxifen | 13.51 | 11731420 19196723 14580682 16827153 19196722 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Tetradecanoylphorbol Acetate | 13.51 | 8985016 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 12.14 | 19453300 | |
| MESH:D020149 | Manganese Poisoning | Tamoxifen | 12.14 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.73 | 17453147 | |
| MESH:D008545 | Melanoma | Isotretinoin | 5.08 | 17237267 | |
| MESH:D008545 | Melanoma | Tamoxifen | 5.08 | 19393235 12393984 | |
| MESH:D008545 | Melanoma | Tretinoin | 5.08 | 16752155 | |
| MESH:D018328 | Melanoma, Amelanotic | Tamoxifen | 4.03 | 15990972 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 4.27 | 16940565 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 4.64 | 16801185 | |
| MESH:D018200 | Mixed Tumor, Mullerian | Raloxifene | 5.40 | 15863610 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.07 | 16381670 | |
| MESH:D009101 | Multiple Myeloma | Raloxifene | 3.33 | 16497877 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 2.99 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | Genistein | 5.78 | 17141266 | |
| MESH:D009203 | Myocardial Infarction | Quercetin | 5.78 | 19595682 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 13.61 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Genistein | 13.61 | 17141266 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Quercetin | 13.61 | 19207477 | |
| MESH:D009232 | Myxoma | Raloxifene | 5.40 | 16343187 | |
| MESH:D009362 | Neoplasm Metastasis | Tamoxifen | 2.49 | 19393235 | |
| MESH:D009364 | Neoplasm Recurrence, Local | Tamoxifen | 2.47 | 19410462 | |
| MESH:D009369 | Neoplasms | alitretinoin | 11.31 | 16946489 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 11.31 | 11141357 | |
| MESH:D009369 | Neoplasms | Quercetin | 11.31 | 15185748 | |
| MESH:D009369 | Neoplasms | Tretinoin | 11.31 | 16594593 16946489 | |
| MESH:D009376 | Neoplasms, Hormone-Dependent | Tamoxifen | 3.85 | 19196722 19189210 19200415 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 3.58 | 17289903 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 4.29 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 3.15 | 18481113 19348381 | |
| MESH:D009421 | Nervous System Malformations | bisphenol A | 22.26 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 22.26 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Genistein | 22.26 | 16427766 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 22.26 | 9125849 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 2.96 | 9142499 | |
| MESH:D009447 | Neuroblastoma | Isotretinoin | 3.97 | 17368321 | |
| MESH:D020078 | Neurogenic Inflammation | Quercetin | 4.22 | 17929310 | |
| MESH:D010024 | Osteoporosis | Genistein | 7.02 | 19401787 | |
| MESH:D010024 | Osteoporosis | Raloxifene | 7.02 | 17882678 19059307 15775268 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Genistein | 16.07 | 16169203 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Quercetin | 16.07 | 19495926 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Raloxifene | 16.07 | 15758505 17823083 17893378 15579764 | |
| MESH:D010049 | Ovarian Diseases | bisphenol A | 4.84 | 11985600 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 10.92 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Genistein | 10.92 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | Quercetin | 10.92 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 10.92 | 16936753 | |
| MESH:D010146 | Pain | Tretinoin | 2.78 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | Quercetin | 8.44 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Tetradecanoylphorbol Acetate | 8.44 | 15976015 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 8.44 | 15976015 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 3.54 | 11578682 | |
| MESH:D010212 | Papilloma | Tetradecanoylphorbol Acetate | 4.14 | 8330346 18404319 12065085 18922899 | |
| MESH:D011014 | Pneumonia | Lipopolysaccharides | 4.40 | 11605937 12224865 | |
| MESH:D017499 | Porokeratosis | alitretinoin | 5.85 | 16144296 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 8.67 | 12371664 | |
| MESH:D011230 | Precancerous Conditions | Quercetin | 8.67 | 19056647 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 15.60 | 10548101 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Isotretinoin | 15.60 | 18769834 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | vinclozolin | 15.60 | 18042343 18220299 19015723 | |
| MESH:D011469 | Prostatic Diseases | vinclozolin | 4.78 | 18220299 | |
| MESH:D011470 | Prostatic Hyperplasia | Calcitriol | 4.63 | 15572423 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 10.09 | 20887781 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 10.09 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.43 | 17292933 | |
| MESH:D011471 | Prostatic Neoplasms | bisphenol A | 2.43 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Calcitriol | 2.43 | 18247401 16289102 15754350 12479363 16644109 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 2.43 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Genistein | 2.43 | 15256057 15378649 16925846 | |
| MESH:D011471 | Prostatic Neoplasms | Quercetin | 2.43 | 17292933 14715546 | |
| MESH:D011471 | Prostatic Neoplasms | Raloxifene | 2.43 | 15731164 16536755 16220300 | |
| MESH:D011471 | Prostatic Neoplasms | Tamoxifen | 2.43 | 15067354 | |
| MESH:D011472 | Prostatitis | vinclozolin | 4.78 | 18629315 | |
| MESH:D011507 | Proteinuria | Tretinoin | 3.46 | 16636307 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 3.16 | 15861022 16919318 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 2.18 | 16882103 | |
| MESH:D011596 | Psychomotor Disorders | Isotretinoin | 5.77 | 18769834 | |
| MESH:D011625 | Pterygium | Tretinoin | 4.64 | 16723453 | |
| MESH:D011629 | Puberty, Precocious | bisphenol A | 4.63 | 10548101 | |
| MESH:D011693 | Purpura | Raloxifene | 5.40 | 15770314 | |
| MESH:D012130 | Respiratory Hypersensitivity | Lipopolysaccharides | 3.63 | 10835634 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 3.96 | 16116481 16283617 | |
| MESH:D012554 | Schistosomiasis japonica | Quercetin | 5.39 | 16862918 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 9.14 | 19755658 10029692 | |
| MESH:D012878 | Skin Neoplasms | Tetradecanoylphorbol Acetate | 9.14 | 18404319 11807781 8330346 12065085 8985016 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 9.14 | 16467112 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 11.06 | 16709447 | |
| MESH:D013088 | Spermatocele | Tamoxifen | 11.06 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Tamoxifen | 3.89 | 19457130 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 2.31 | 2093021 20155912 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 2.31 | 17261132 | |
| MESH:D020521 | Stroke | Raloxifene | 3.70 | 16837676 | |
| MESH:D019966 | Substance-Related Disorders | bisphenol A | 3.83 | 16045194 16684133 | |
| MESH:D013921 | Thrombocytopenia | Lipopolysaccharides | 4.03 | 15821434 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 3.48 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 3.02 | 15669648 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 2.91 | 17045167 16026305 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 13.21 | 19048282 | |
| MESH:D013978 | Tibial Fractures | Raloxifene | 13.21 | 19048282 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 3.65 | 16051514 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 3.13 | 16040207 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 11.47 | 17053015 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Quercetin | 11.47 | 16720314 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Raloxifene | 11.47 | 17572228 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Tamoxifen | 11.47 | 16712894 8653321 17572228 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 3.54 | 16129372 | |
| MESH:D014591 | Uterine Diseases | bisphenol A | 4.86 | 14652134 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 3.15 | 14692618 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 4.46 | 16752155 | |
| MESH:D014605 | Uveitis | Cyclosporine | 3.83 | 1336536 | |
| MESH:D054556 | Venous Thromboembolism | Raloxifene | 5.06 | 16837676 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 3.40 | 14671159 15869587 | |
| MESH:D014820 | Vitiligo | Tretinoin | 3.91 | 16761959 | |
| MESH:D014846 | Vulvar Neoplasms | Raloxifene | 5.40 | 16343187 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 3.84 | 16287080 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 4.29 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:05146 | Amoebiasis |