Annotation Detail for ATP6V1E1


Gene Symbol: | ATP6V1E1 ( ATP6E,ATP6E2,ATP6V1E,P31,Vma4 ) |
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Gene Full Name: | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 |
Band: | 22q11.21 |
Quick Links | Entrez ID:529; OMIM: 108746; Uniprot ID:VATE1_HUMAN; ENSEMBL ID: ENSG00000131100; HGNC ID: 857 |
Relate to Another Database: | SFARIGene; denovo-db |
No data |
Pathway ID | Pathway Name |
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hsa04145 | Phagosome |
hsa05120 | Epithelial cell signaling in Helicobacter pylori infection |
hsa04966 | Collecting duct acid secretion |
hsa00190 | Oxidative phosphorylation |
hsa01100 | Metabolic pathways |
hsa05110 | Vibrio cholerae infection |
Pathway ID | Pathway Name |
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Signaling by Insulin receptor |
No data |
No data |
No data |
Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
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D000082 | Acetaminophen | Acetaminophen affects the expression of ATP6V1E1 mRNA | affects expression | 17562736 |
D007657 | Ketone Bodies | Ketone Bodies results in increased expression of ATP6V1E1 mRNA | increases expression | 16807920 |
D010665 | Phenylpropanolamine | Phenylpropanolamine results in decreased expression of ATP6V1E1 mRNA | decreases expression | 16465460 |
C025299 | polyphenols | polyphenols results in decreased expression of ATP6V1E1 mRNA | decreases expression | 16293270 |
C021751 | tanshinone | tanshinone results in increased expression of ATP6V1E1 mRNA | increases expression | 15849732 |
Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
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MESH:D000799 | Angioedema | Acetaminophen | 4.45 | 10982225 | |
MESH:D000855 | Anorexia | Phenylpropanolamine | 6.08 | 17684035 | |
MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
MESH:D001943 | Breast Neoplasms | tanshinone | 3.59 | 19885617 15849732 | |
MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.40 | 3084413 | |
MESH:D002386 | Cataract | Acetaminophen | 2.77 | 10977129 | |
MESH:D003110 | Colonic Neoplasms | polyphenols | 2.72 | 16293270 | |
MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 4.28 | 16485898 11461765 12594235 14725611 15619225 18713872 17562736 10663392 2444490 11529661 12958197 11743745 11834606 19739265 19370779 11739529 16227642 19416960 19923254 16781746 11421492 16177239 16393943 15968718 12392966 19085960 10774834 12705907 19420014 17906064 12153990 11287661 12540782 16109766 17522070 10915739 14986274 18071297 19164858 16081117 14550746 | |
MESH:D056486 | Drug-Induced Liver Injury | polyphenols | 4.28 | 19370779 | |
MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.71 | 19426721 | |
MESH:D005756 | Gastritis | Acetaminophen | 4.29 | 16983495 | |
MESH:D005910 | Glioma | tanshinone | 4.14 | 16955220 | |
MESH:D006930 | Hyperalgesia | Acetaminophen | 2.99 | 16870215 | |
MESH:D017379 | Hypertrophy, Left Ventricular | tanshinone | 5.59 | 19662366 | |
MESH:D007249 | Inflammation | polyphenols | 3.22 | 16366677 | |
MESH:D007674 | Kidney Diseases | Acetaminophen | 2.38 | 12587719 15629191 | |
MESH:D008107 | Liver Diseases | Acetaminophen | 4.40 | 19784758 16611625 19014921 12969438 11587558 12587719 16610002 19460945 | |
MESH:D008107 | Liver Diseases | polyphenols | 4.40 | 16698588 | |
MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.58 | 17185352 16871587 | |
MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.05 | 19513568 | |
MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.18 | 18514411 | |
MESH:D010146 | Pain | Acetaminophen | 2.69 | 16870215 | |
MESH:D013705 | Temporomandibular Joint Disorders | polyphenols | 5.86 | 17997062 | |
MESH:D014581 | Urticaria | Acetaminophen | 3.38 | 10982225 |
Pathway ID | Pathway Name |
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KEGG:04966 | Collecting duct acid secretion |
KEGG:05120 | Epithelial cell signaling in Helicobacter pylori infection |
KEGG:01100 | Metabolic pathways |
KEGG:00190 | Oxidative phosphorylation |
KEGG:04145 | Phagosome |
KEGG:05323 | Rheumatoid arthritis |
REACT:498 | Signaling by Insulin receptor |
REACT:15518 | Transmembrane transport of small molecules |
KEGG:05110 | Vibrio cholerae infection |