AutismKB 2.0

Annotation Detail for PLAT


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Basic Information Top
Gene Symbol:PLAT ( DKFZp686I03148,T-PA,TPA )
Gene Full Name: plasminogen activator, tissue
Band: 8p11.21
Quick LinksEntrez ID:5327; OMIM: 173370; Uniprot ID:TPA_HUMAN; ENSEMBL ID: ENSG00000104368; HGNC ID: 9051
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04610Complement and coagulation cascades
Pathway IDPathway Name
Hemostasis
Signaling by PDGF
Pathway IDPathway Name
200108amb2 Integrin signaling
Pathway IDPathway Name
P00050Plasminogen activating cascade
P00011Blood coagulation
Pathway IDPathway Name
500304Dissolution of Fibrin Clot
500508Signaling by PDGF
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1701Antiphospholipid syndrome
1743Late pregnancy
1781Rheumatoid arthritis
1803Periodontitis
1858Hemorrhagic disorder
1859Ovarian cancer
1877Multiple sclerosis
1878Ischemia
1904Diabetes mellitus
1918Atherosclerosis
1954Stroke
2008Liver disease
2091Hypertension
2051Leukemia
2066Lung cancer
2102Polycystic ovary syndrome
2106Pancreas cancer
2111Systemic infection
Desease Name
tissue-type plasminogen activator levels
CARDIOVASCULAR
gastric ulcer
vascular t-PA release
Stroke
Myocardial Infarction
No data
Desease Name
Thrombophilia, familial, due to decreased release of PLAT
Hyperfibrinolysis, familial, due to increased release of PLAT
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C090942 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin promotes the reaction [SP1 protein binds to PLAT promoter]]affects binding|decreases reaction|increases reaction 18419748
C090942 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of PLAT mRNA]decreases reaction|increases expression 18419748
C090942 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased secretion of PLAT protein]decreases reaction|increases secretion 18419748
C051327 4-amidino-2-nitrophenyl 4'-anisate PLAT protein results in increased metabolism of 4-amidino-2-nitrophenyl 4'-anisateincreases metabolic processing 3101668
C002202 4-oxoretinoic acid 4-oxoretinoic acid results in increased expression of PLAT mRNAincreases expression 15982314
D000082 Acetaminophen Acetaminophen affects the expression of PLAT mRNAaffects expression 17562736
C103303 alitretinoin alitretinoin results in increased expression of PLAT mRNAincreases expression 15982314
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PLAT mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of PLAT mRNAdecreases expression 20458559
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of PLAT mRNAincreases expression 20064835
C095105 bexarotene bexarotene results in increased expression of PLAT mRNAincreases expression 17178900
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene inhibits the reaction [LPA protein modified form results in decreased expression of PLAT protein]decreases expression|decreases reaction 10856522
D002084 Butylated Hydroxytoluene Butylated Hydroxytoluene inhibits the reaction [LPA protein modified form results in increased expression of PLAT protein]decreases reaction|increases expression 10856522
D002251 Carbon Tetrachloride PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of IFNG protein]affects reaction|increases expression 18279442
D002251 Carbon Tetrachloride PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of IL10 protein]affects reaction|increases expression 18279442
D002251 Carbon Tetrachloride PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of IL4 protein]affects reaction|increases expression 18279442
D002251 Carbon Tetrachloride PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of MMP13 protein]affects reaction|increases expression 17944888
D002251 Carbon Tetrachloride PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of MMP2 protein]affects reaction|increases expression 17944888
D002251 Carbon Tetrachloride PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of MMP9 protein]affects reaction|increases expression 17944888
D002251 Carbon Tetrachloride PLAT protein affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]affects reaction|increases expression 17944888
D002392 Catechin Catechin results in increased expression of PLAT mRNAincreases expression 11236827
D002392 Catechin Catechin results in increased expression of PLAT proteinincreases expression 11236827
D002392 Catechin Dactinomycin inhibits the reaction [Catechin results in increased expression of PLAT mRNA]decreases reaction|increases expression 11236827
D002392 Catechin Catechin results in increased expression of PLAT mRNAincreases expression 17478321
D002713 Chlorine [Ozone co-treated with Chlorine] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 18636392
D003513 Cycloheximide Cycloheximide promotes the reaction [Isoproterenol results in increased expression of PLAT mRNA]increases expression|increases reaction 2477232
D003609 Dactinomycin Dactinomycin inhibits the reaction [Catechin results in increased expression of PLAT mRNA]decreases reaction|increases expression 11236827
D003609 Dactinomycin Dactinomycin inhibits the reaction [Quercetin results in increased expression of PLAT mRNA]decreases reaction|increases expression 11236827
D003609 Dactinomycin Dactinomycin inhibits the reaction [resveratrol results in increased expression of PLAT mRNA]decreases reaction|increases expression 11236827
D003907 Dexamethasone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 16054899
D003907 Dexamethasone Dexamethasone inhibits the reaction [IL1B protein results in increased activity of PLAT protein]decreases reaction|increases activity 15963473
D003907 Dexamethasone Dexamethasone inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]decreases reaction|increases expression 15963473
D003907 Dexamethasone Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]]decreases reaction|increases expression 15963473
D003907 Dexamethasone RU 43044 inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]]decreases reaction|increases expression 15963473
C023635 dienogest [Ethinyl Estradiol co-treated with dienogest] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 15288212
D004041 Dietary Fats Dietary Fats results in increased expression of PLAT mRNAincreases expression 18042831
C045651 epigallocatechin gallate [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 12628509
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of PLAT mRNAincreases expression 15219790
19619570
C454300 estradiol valerate-dienogest [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 15288212
D000431 Ethanol Ethanol results in increased expression of PLAT mRNAincreases expression 17478321
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with dienogest] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with estradiol valerate-dienogest] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 15288212
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Gestodene] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 12618251
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Gestodene] results in increased activity of PLAT proteinaffects cotreatment|increases activity 12618251
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 12618251
15288212
15157790
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased activity of PLAT proteinaffects cotreatment|increases activity 12618251
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 12618251
D004997 Ethinyl Estradiol [Ethinyl Estradiol co-treated with norgestimate] results in increased activity of PLAT proteinaffects cotreatment|increases activity 12618251
C442659 ethinyl estradiol-desogestrel combination ethinyl estradiol-desogestrel combination results in decreased expression of PLAT proteindecreases expression 12618251
C442659 ethinyl estradiol-desogestrel combination ethinyl estradiol-desogestrel combination results in increased activity of PLAT proteinincreases activity 12618251
D005472 Fluorouracil Fluorouracil results in increased expression of PLAT mRNAincreases expression 16101138
C033273 Gestodene [Ethinyl Estradiol co-treated with Gestodene] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 12618251
C033273 Gestodene [Ethinyl Estradiol co-treated with Gestodene] results in increased activity of PLAT proteinaffects cotreatment|increases activity 12618251
C495287 HMR 3339 HMR 3339 results in decreased expression of PLAT proteindecreases expression 16202731
D007213 Indomethacin Indomethacin inhibits the reaction [GNRH1 protein results in increased expression of PLAT mRNA]decreases reaction|increases expression 16514196
C051890 irinotecan irinotecan analog results in decreased expression of PLAT mRNAdecreases expression 18927307
D015056 1-Methyl-3-isobutylxanthine [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 16054899
D007545 Isoproterenol Cycloheximide promotes the reaction [Isoproterenol results in increased expression of PLAT mRNA]increases expression|increases reaction 2477232
D007545 Isoproterenol Isoproterenol results in increased expression of PLAT mRNAincreases expression 2477232
D007545 Isoproterenol Isoproterenol results in increased secretion of PLAT proteinincreases secretion 2477232
D008294 Malathion Malathion results in decreased expression of PLAT mRNAdecreases expression 16079077
D015735 Mifepristone Mifepristone results in increased expression of PLAT mRNAincreases expression 17584828
D015735 Mifepristone Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]]decreases reaction|increases expression 15963473
D008942 Mitoxantrone PLAT protein affects the susceptibility to Mitoxantroneaffects response to substance 16217747
D009151 Mustard Gas Mustard Gas affects the expression of PLAT mRNAaffects expression 15651846
C029938 nickel sulfate nickel sulfate results in increased expression of PLAT mRNAincreases expression 16780908
C029938 nickel sulfate nickel sulfate results in increased expression of PLAT mRNAincreases expression 16100012
D004963 Estrenes Estrenes analog results in increased expression of PLAT mRNAincreases expression 15219790
C017576 norgestimate [Ethinyl Estradiol co-treated with norgestimate] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 12618251
C017576 norgestimate [Ethinyl Estradiol co-treated with norgestimate] results in increased activity of PLAT proteinaffects cotreatment|increases activity 12618251
D016912 Levonorgestrel [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of PLAT proteinaffects cotreatment|decreases expression 15157790
12618251
15288212
D016912 Levonorgestrel [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased activity of PLAT proteinaffects cotreatment|increases activity 12618251
C516519 NuvaRing NuvaRing results in decreased expression of PLAT proteindecreases expression 15157790
D010126 Ozone [Ozone co-treated with Chlorine] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 18636392
C041786 palm oil palm oil results in increased expression of PLAT mRNAincreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of PLAT mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of PLAT mRNAincreases expression 19482888
C005435 phenylmethylpyrazolone phenylmethylpyrazolone inhibits the reaction [PLAT protein results in increased activity of RELA protein]decreases reaction|increases activity 19095969
C005435 phenylmethylpyrazolone phenylmethylpyrazolone inhibits the reaction [PLAT protein results in increased expression of and results in increased activity of MMP9 protein]decreases reaction|increases activity|increases expression 19095969
C005435 phenylmethylpyrazolone phenylmethylpyrazolone inhibits the reaction [PLAT protein results in increased expression of MMP9 mRNA]decreases reaction|increases expression 19095969
C004479 pimagedine pimagedine inhibits the reaction [LPA protein modified form results in decreased expression of PLAT protein]decreases expression|decreases reaction 10856522
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PLAT mRNAaffects binding|increases activity|increases expression 19710929
C035988 procymidone procymidone results in decreased expression of PLAT mRNAdecreases expression 15686871
D011794 Quercetin 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin promotes the reaction [SP1 protein binds to PLAT promoter]]affects binding|decreases reaction|increases reaction 18419748
D011794 Quercetin 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of PLAT mRNA]decreases reaction|increases expression 18419748
D011794 Quercetin 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased secretion of PLAT protein]decreases reaction|increases secretion 18419748
D011794 Quercetin Dactinomycin inhibits the reaction [Quercetin results in increased expression of PLAT mRNA]decreases reaction|increases expression 11236827
D011794 Quercetin Quercetin promotes the reaction [SP1 protein binds to PLAT promoter]affects binding|increases reaction 18419748
D011794 Quercetin Quercetin results in increased expression of PLAT mRNAincreases expression 11236827
18419748
D011794 Quercetin Quercetin results in increased expression of PLAT proteinincreases expression 11236827
D011794 Quercetin Quercetin results in increased secretion of PLAT proteinincreases secretion 18419748
D011794 Quercetin Quercetin results in increased expression of PLAT mRNAincreases expression 17478321
18095365
C059514 resveratrol Dactinomycin inhibits the reaction [resveratrol results in increased expression of PLAT mRNA]decreases reaction|increases expression 11236827
C059514 resveratrol resveratrol results in increased expression of PLAT mRNAincreases expression 11236827
C059514 resveratrol resveratrol results in increased expression of PLAT proteinincreases expression 11236827
D015474 Isotretinoin Isotretinoin results in increased expression of PLAT mRNAincreases expression 15982314
D012176 Retinoids Retinoids results in increased expression of PLATincreases expression 7556191
D012176 Retinoids Ro 41-5253 inhibits the reaction [Retinoids results in increased expression of PLAT]decreases reaction|increases expression 7556191
C084904 Ro 41-5253 Ro 41-5253 inhibits the reaction [Retinoids results in increased expression of PLAT]decreases reaction|increases expression 7556191
C116926 rofecoxib rofecoxib results in increased expression of PLAT mRNAincreases expression 16580899
C089730 rosiglitazone [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 16054899
C423603 RU 24858 RU 24858 inhibits the reaction [IL1B protein results in increased activity of PLAT protein]decreases reaction|increases activity 15963473
C423603 RU 24858 RU 24858 inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]decreases reaction|increases expression 15963473
C085917 RU 43044 RU 43044 inhibits the reaction [Dexamethasone inhibits the reaction [IL1B protein results in increased expression of PLAT mRNA]]decreases reaction|increases expression 15963473
C017947 sodium arsenite sodium arsenite results in increased expression of PLAT mRNAincreases expression 16014739
D013467 Sulindac [Sulindac co-treated with epigallocatechin gallate] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 12628509
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PLAT mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PLAT mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin CGA protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLAT protein]decreases reaction|increases expression 12128104
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PLAT mRNAincreases expression 11752688
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PLAT proteinincreases expression 12128104
D014192 Trapidil Trapidil affects the reaction [PTH protein affects the expression of PLAT mRNA]affects expression|affects reaction 18635661
D014212 Tretinoin Tretinoin metabolite results in increased expression of PLAT mRNAincreases expression 15982314
D014212 Tretinoin Tretinoin results in increased expression of PLAT mRNAincreases expression 17431108
17138961
16012519
15982314
D014212 Tretinoin Tretinoin results in increased expression of PLAT mRNAincreases expression 16604517
C025643 vinclozolin vinclozolin results in decreased expression of PLAT mRNAdecreases expression 15686871
D002762 Cholecalciferol Cholecalciferol results in increased expression of PLAT mRNAincreases expression 17170073
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 4.8414745880
MESH:D000014 Abnormalities, Drug-Induced Ethanol 15.1918926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 15.1918769834
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 15.196195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 15.1915322242 14514962 11752688
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.4018769834
MESH:D000138 Acidosis Ammonium Chloride 8.3518287403
MESH:D000138 Acidosis Ethanol 8.3511192467
MESH:D017486 Acneiform Eruptions Isotretinoin 5.6316232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 16.7417505938
MESH:D000152 Acne Vulgaris Isotretinoin 16.7418769834 16185265
MESH:D000152 Acne Vulgaris norgestimate 16.7417505938
MESH:D058186 Acute Kidney Injury resveratrol 7.1116538975
MESH:D058186 Acute Kidney Injury Sulindac 7.117897758
MESH:D055371 Acute Lung Injury Chlorine 11.9520601635
MESH:D055371 Acute Lung Injury nickel sulfate 11.9519131640 16100012 12718980 11954676
MESH:D055371 Acute Lung Injury pirinixic acid 11.9518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 17.5519825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 17.5520127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 17.5511473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 17.5514692618
MESH:D000230 Adenocarcinoma Fluorouracil 17.5517638652
MESH:D000230 Adenocarcinoma Indomethacin 17.5516537180
MESH:D000230 Adenocarcinoma Sulindac 17.5511910360
MESH:D000236 Adenoma Benzo(a)pyrene 12.716695378
MESH:D000236 Adenoma Indomethacin 12.7111497255
MESH:D000236 Adenoma resveratrol 12.7115688382
MESH:D000236 Adenoma Sulindac 12.7110223192
MESH:D018248 Adenoma, Liver Cell Phenobarbital 13.5917620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 13.5916434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 13.5916835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.0412394442 17611924 11535846 11874996 19003578 16460482 15623613
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.0515276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.2517306315 16712894
MESH:D000382 Agricultural Workers' Diseases Malathion 4.3517119214 11874814
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.6615451039 15451040
MESH:D000505 Alopecia Tretinoin 3.1015955085
MESH:D016301 Alveolar Bone Loss Indomethacin 4.7217225004
MESH:D000544 Alzheimer Disease Indomethacin 7.8517627676 15579461
MESH:D000544 Alzheimer Disease Ozone 7.8515513908
MESH:D000544 Alzheimer Disease resveratrol 7.8516162502 16183991
MESH:D000544 Alzheimer Disease rosiglitazone 7.8519621015
MESH:D000740 Anemia Fluorouracil 6.8217963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 6.8211748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.6617084956
MESH:D000799 Angioedema Acetaminophen 3.1910982225
MESH:D000853 Anophthalmos Ethanol 4.1915513904
MESH:D001008 Anxiety Disorders Ethanol 7.2911141031
MESH:D001008 Anxiety Disorders vinclozolin 7.2919015723
MESH:D001014 Aortic Aneurysm Indomethacin 4.2410231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.6319183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 9.6310388637
MESH:D001161 Arteriosclerosis Dietary Fats 7.8415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 7.8411256880
MESH:D018771 Arthralgia Indomethacin 4.512160914
MESH:D001169 Arthritis, Experimental Dexamethasone 18.5217659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 18.5215885639
MESH:D001169 Arthritis, Experimental resveratrol 18.5217115116
MESH:D001169 Arthritis, Experimental rofecoxib 18.5216690336
MESH:D001169 Arthritis, Experimental Tretinoin 18.5216412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 8.9611248219
MESH:D001172 Arthritis, Rheumatoid Ozone 8.9615570426
MESH:D001172 Arthritis, Rheumatoid phenylmethylpyrazolone 8.9616390820
MESH:D001172 Arthritis, Rheumatoid Tretinoin 8.9616292516
MESH:D001249 Asthma epigallocatechin gallate 9.2816516891
MESH:D001249 Asthma Mustard Gas 9.2810378619
MESH:D001249 Asthma Ozone 9.2817854713 16373670
MESH:D001249 Asthma Tretinoin 9.2816456186
MESH:D001260 Ataxia Telangiectasia Quercetin 4.3415336622
MESH:D050197 Atherosclerosis resveratrol 2.8717967414 16873680
MESH:D001321 Autistic Disorder Acetaminophen 1.5218445737
MESH:D001327 Autoimmune Diseases Cholecalciferol 14.6416142846
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 14.6419761891
MESH:D001327 Autoimmune Diseases Quercetin 14.6419761891
MESH:D001471 Barrett Esophagus Tretinoin 3.7916935849
MESH:D001477 Bartter Syndrome Indomethacin 4.3610684365
MESH:D001768 Blister Mustard Gas 4.5219167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 17.2316206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 17.2319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 17.2312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 17.2316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3215746008
MESH:D019046 Bone Marrow Neoplasms Dactinomycin 4.8814601052
MESH:D001913 Bowen's Disease Sulindac 4.7011207687
MESH:D001919 Bradycardia Isoproterenol 4.556740701
MESH:D001929 Brain Edema Indomethacin 4.3711481608
MESH:D002545 Brain Ischemia Indomethacin 8.2312524144
MESH:D002545 Brain Ischemia resveratrol 8.2317600658
MESH:D001943 Breast Neoplasms alitretinoin 11.0816344269
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 11.0820146248 17474063
MESH:D001943 Breast Neoplasms bexarotene 11.0816344269 16818667
MESH:D001943 Breast Neoplasms Dietary Fats 11.0820435547
MESH:D001943 Breast Neoplasms Estradiol 11.0817289903 17261762 14630087 16675129 12948864 17018787 18497071 19861407
MESH:D001943 Breast Neoplasms Fluorouracil 11.0815136595 16595493 16557594 19217205 18357371 18608205 16110121
MESH:D001943 Breast Neoplasms Indomethacin 11.0817401462
MESH:D001943 Breast Neoplasms Malathion 11.0812762645
MESH:D001943 Breast Neoplasms Quercetin 11.0818628248
MESH:D001943 Breast Neoplasms resveratrol 11.0816393696 17651959 17534123
MESH:D001943 Breast Neoplasms Retinoids 11.0817491551 19340624 17368321
MESH:D001943 Breast Neoplasms Sulindac 11.0816642371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 11.0820435547
MESH:D001943 Breast Neoplasms Tretinoin 11.0816443354 16166294 16873071
MESH:D016535 Bronchial Hyperreactivity Ozone 3.1617626835 14754758 15516495 18417511 19059883 18315731 16777450
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.5215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.3217687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 3.9516813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.7311589617
MESH:D002056 Burns Ethanol 9.3016374292
MESH:D002056 Burns Indomethacin 9.3010459503
MESH:D002100 Cachexia Indomethacin 10.2716537180 15141370 11239499 15625704
MESH:D002100 Cachexia Ozone 10.2716183385
MESH:D002105 Cadmium Poisoning Quercetin 4.8916962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 3.8216111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.163786805 16097048 16192424 15700767 18705752 16227642 16050911 16124888 10355542 15721981 16011737 15673190
MESH:D002276 Carcinoid Tumor Fluorouracil 4.0116051944
MESH:D002277 Carcinoma Fluorouracil 6.4717121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.4716835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.5016168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 25.483084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 25.4814691202 16217749 15553829 11135700 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 25.4818788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 25.4816924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 25.4815289165 15763234 18788625
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 25.4817088986 16799960 16332177 18930000 17971768 17045692
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 25.4816391822
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 25.4817173139 20007298 1701930 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 25.4819519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 25.4819321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 25.4816507464 17306315 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 25.481917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 9.3011053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.3016675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.7111352223 18791128 14736730
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 2.9716247446
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3317234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.2219014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 5.6018695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 5.6017341418
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.5512490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 18.3120419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 18.3118986760 16280240 17066447 16757204
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 18.3112636206 15482327
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 18.3111237771
MESH:D002294 Carcinoma, Squamous Cell resveratrol 18.3116227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 18.3118572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 18.3116051514 16096774
MESH:D006332 Cardiomegaly Ethanol 13.1519332462
MESH:D006332 Cardiomegaly Isoproterenol 13.1511179087 7544033
MESH:D006332 Cardiomegaly Quercetin 13.1519794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 13.1518670907 18850075 16120746
MESH:D009202 Cardiomyopathies pimagedine 4.4316612575
MESH:D002318 Cardiovascular Diseases resveratrol 3.0215458977
MESH:D002386 Cataract Acetaminophen 10.1410977129
MESH:D002386 Cataract pimagedine 10.1417936468 15003327
MESH:D002386 Cataract Tretinoin 10.1417460283
MESH:D002471 Cell Transformation, Neoplastic Estradiol 5.2118566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 5.2119524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.634080065
MESH:D002543 Cerebral Hemorrhage marker/mechanism 19095969
MESH:D002543 Cerebral Hemorrhage phenylmethylpyrazolone 5.2019095969
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 3.9516129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.6116835633
MESH:D002764 Cholecystitis Indomethacin 4.5111181007
MESH:D002779 Cholestasis Ethinyl Estradiol 10.7717333356 11677210 17110522 16919318 16105132 15861022 17681005
MESH:D002779 Cholestasis Levonorgestrel 10.7715861022
MESH:D002779 Cholestasis pirinixic acid 10.7719176532
MESH:D002822 Choriocarcinoma Tretinoin 4.5016461808
MESH:D002971 Cleft Lip Ethanol 3.2115513904
MESH:D002972 Cleft Palate Ethanol 8.0015513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 8.0012621046 15340226 15668235 8697196 16354765
MESH:D002972 Cleft Palate Tretinoin 8.009407595
MESH:D003092 Colitis resveratrol 7.5616474422
MESH:D003092 Colitis Tretinoin 7.5617035595
MESH:D003110 Colonic Neoplasms Dexamethasone 17.6015824018
MESH:D003110 Colonic Neoplasms Fluorouracil 17.6017018589 18772588 17287894 16510598 16340194 17725105 17172411 15001691 17169374 17016597
MESH:D003110 Colonic Neoplasms Indomethacin 17.6015963497 15936596 15786552 15637740 15625704 11260862
MESH:D003110 Colonic Neoplasms irinotecan 17.6017725105 17287894
MESH:D003110 Colonic Neoplasms Quercetin 17.6011134977 15741050 17148506 17191121 19056647 19440933 16640504
MESH:D003110 Colonic Neoplasms resveratrol 17.6016338953
MESH:D003110 Colonic Neoplasms rofecoxib 17.6012902858
MESH:D003110 Colonic Neoplasms Sulindac 17.6012458338 12902858
MESH:D015179 Colorectal Neoplasms arsenic trioxide 9.0420501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 9.0417401013 17454858 17695437 17094418 16524972 16303861 16331619 17594712 18802399 18949393 20501625 17016601 16282729 16391804 15148649 18509181 18448328 15289873 17255274 18288408 18383874 14970324
MESH:D015179 Colorectal Neoplasms Indomethacin 9.0418059344 17054584 11197048 12606626
MESH:D015179 Colorectal Neoplasms irinotecan 9.0417454858 16391804 18509181 16303861 18259882 15273666 17159606
MESH:D015179 Colorectal Neoplasms Quercetin 9.0418095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 9.0416550006
MESH:D015179 Colorectal Neoplasms Sulindac 9.0411197048 10666051 11076880 18059344
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.5114669216 17141729
MESH:D003327 Coronary Disease resveratrol 3.3116507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.5712609071
MESH:D018352 Coronavirus Infections Indomethacin 5.0617302372
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 8.1010525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 8.1017728286
MESH:D019465 Craniofacial Abnormalities Ethanol 8.1011198716 15451039 10194807 19302082 11873399 15513904 15451040
MESH:D019465 Craniofacial Abnormalities Isotretinoin 8.109879862 18769834
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.1015322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.109211117 9664655 9125849 16925845 8800419 14991402 9142499 10589399 9224671 17551590
MESH:D003456 Cryptorchidism vinclozolin 3.7314966744
MESH:D007644 Darier Disease Fluorouracil 4.1516733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.5015213294
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 5.3512438553
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 5.3516780908 16823706 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.0918249437
MESH:D003920 Diabetes Mellitus rosiglitazone 3.7617446233
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.8019496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.8016873680
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 6.0916988119
MESH:D003924 Diabetes Mellitus, Type 2 rosiglitazone 6.0912642470
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.0917107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.2019279558
MESH:D003928 Diabetic Nephropathies resveratrol 7.2016286809
MESH:D003930 Diabetic Retinopathy Sulindac 4.5712861449 17621415
MESH:D003967 Diarrhea Dexamethasone 6.287237001
MESH:D003967 Diarrhea Indomethacin 6.287907874 7237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.9810774834 18071297 14725611 12153990 16393943 10915739 17522070 19420014 16781746 11743745 11421492 19164858 16109766 12540782 16177239 18713872 19370779 11287661 19085960 11739529 12958197 10663392 12705907 12594235 16485898 11529661 12392966 15619225 15968718 17906064 19416960 2444490 14986274 14550746 11461765 19923254 19739265 17562736 11834606 16227642 16081117
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.9815027814 9327722 3786805 16177239 3732212 4309450 7440962 2869522 15998439 21278145 11566570 17522070 6623471 10915739 16227642 19085960 7120509 15968718 10092053 6884620 7179309 19336974
MESH:D056486 Drug-Induced Liver Injury Ethanol 6.9811566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.9820420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4419426721
MESH:D004362 Drug Toxicity phenylmethylpyrazolone 6.9112231392 12649298
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.9111462148
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.5118446180 16133044 18043480 16326151 17190690 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 3.5311595415 16699067 17329845 17351913 17151854 17202747 11535926 11991626 17045617 11595431 10671773
MESH:D050171 Dyslipidemias Dietary Fats 2.9718367378
MESH:D004417 Dyspnea Chlorine 3.9820016425
MESH:D004421 Dystonia Phenobarbital 3.411851702
MESH:D004485 Eczema Dexamethasone 3.8512438553
MESH:D004487 Edema Dexamethasone 23.9019703484
MESH:D004487 Edema Indomethacin 23.908985016 19703484 7990266 16100529 10653021 7907874 8273558
MESH:D004487 Edema Mustard Gas 23.9011428631 9260866 11428647 11402378
MESH:D004487 Edema pirinixic acid 23.9012083418
MESH:D004487 Edema resveratrol 23.908985016
MESH:D004487 Edema rosiglitazone 23.9012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 23.9012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 9.7718230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 9.7718230668
MESH:D016769 Embolism and Thrombosis therapeutic 9684808
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.1112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 7.1117872969
MESH:D016889 Endometrial Neoplasms Estradiol 5.9311473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 5.9316569247
MESH:D004715 Endometriosis Indomethacin 22.7115652904
MESH:D004715 Endometriosis Mifepristone 22.7116134523
MESH:D004715 Endometriosis rofecoxib 22.7115652904
MESH:D004715 Endometriosis Sulindac 22.7115652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 22.7110568697 9294722
MESH:D019446 Endotoxemia Indomethacin 8.9218509659
MESH:D019446 Endotoxemia phenylmethylpyrazolone 8.9212954792
MESH:D004751 Enteritis Indomethacin 4.0910567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 10.2917980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 10.2917923197
MESH:D004802 Eosinophilia Indomethacin 3.4411298111
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.483659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.223922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.5320417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.006401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.637750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.383659116
MESH:D004890 Erythema Mustard Gas 4.529357497
MESH:D004938 Esophageal Neoplasms arsenic trioxide 14.6212903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 14.6216530937
MESH:D004938 Esophageal Neoplasms Ethanol 14.6216704527
MESH:D004938 Esophageal Neoplasms Fluorouracil 14.6217638652 16337965 16481741 15173087 16785472
MESH:D004938 Esophageal Neoplasms Indomethacin 14.6211005569
MESH:D004938 Esophageal Neoplasms Sulindac 14.6212235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.1911564622
MESH:D005124 Eye Abnormalities Tretinoin 7.199664655 16938888
MESH:D015785 Eye Diseases, Hereditary Retinoids 5.3716968212
MESH:D005234 Fatty Liver arsenic trioxide 33.2715073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 33.2712631006 16239168 15959796 17595544 16045604 19224547 12795759 61145
MESH:D005234 Fatty Liver Dietary Fats 33.2719551842 18296743 17967931 19004024
MESH:D005234 Fatty Liver Ethanol 33.2716409862 18620774 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 33.2715345470
MESH:D005234 Fatty Liver phenylmethylpyrazolone 33.2712795759
MESH:D005234 Fatty Liver pirinixic acid 33.2720131406 19236843
MESH:D005234 Fatty Liver rosiglitazone 33.2719196556
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.0117920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.6610194807 16946407 15451040 15513904
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8311858732
MESH:D005334 Fever Indomethacin 3.5611852909 17627676 10431976
MESH:D018221 Fibromatosis, Abdominal Sulindac 4.8414745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 4.4919069698
MESH:D005354 Fibrosarcoma Indomethacin 4.2510962813
MESH:D005355 Fibrosis Carbon Tetrachloride 26.4618705752
MESH:D005355 Fibrosis Dietary Fats 26.4618296743
MESH:D005355 Fibrosis Indomethacin 26.4617994277
MESH:D005355 Fibrosis Quercetin 26.4619474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 26.4620067830
MESH:D005355 Fibrosis Tretinoin 26.4617994277
MESH:D005499 Folliculitis Indomethacin 4.5111298111
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.6516904648
MESH:D005739 Gas Poisoning Chlorine 4.3620016425
MESH:D005756 Gastritis Acetaminophen 15.2916983495
MESH:D005756 Gastritis Ethanol 15.2915046732
MESH:D005756 Gastritis Indomethacin 15.2915046732
MESH:D005764 Gastroesophageal Reflux Sulindac 4.4011910360
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.2916973722
MESH:D005832 Genital Diseases, Male vinclozolin 4.6516417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.0416452187
MESH:D005909 Glioblastoma Indomethacin 9.4012870263
MESH:D005909 Glioblastoma Quercetin 9.4019804834
MESH:D005909 Glioblastoma Tretinoin 9.4017312396
MESH:D005910 Glioma Fluorouracil 8.2416145905
MESH:D005910 Glioma Indomethacin 8.2418371953 16487511
MESH:D005910 Glioma Quercetin 8.2417643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.7611849393
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9410696789
MESH:D006073 Gout Indomethacin 4.7111248219
MESH:D006258 Head and Neck Neoplasms Fluorouracil 14.7915162350 18337622 15102660
MESH:D006258 Head and Neck Neoplasms Indomethacin 14.7915482327
MESH:D006258 Head and Neck Neoplasms Retinoids 14.7917368321
MESH:D006258 Head and Neck Neoplasms Tretinoin 14.7916096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.5016084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 8.8920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 8.8910048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 8.899664655 14991402
MESH:D006331 Heart Diseases Mitoxantrone 3.6916019553
MESH:D006333 Heart Failure Isoproterenol 5.9618097624
MESH:D006333 Heart Failure pirinixic acid 5.9620558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7611000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 3.9915633222
MESH:D006505 Hepatitis Carbon Tetrachloride 2.9919900420 19110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.0715135802
MESH:D006529 Hepatomegaly Phenobarbital 10.7916109766
MESH:D006529 Hepatomegaly pirinixic acid 10.7919772884 19176532 16221962 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.7915340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.817520565
MESH:D006558 Herpes Genitalis Estradiol 4.3815709030
MESH:D006561 Herpes Simplex resveratrol 3.5516876885
MESH:D006689 Hodgkin Disease sodium arsenite 2.6312676792
MESH:D019584 Hot Flashes Estradiol 3.1017088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.3916959395 15340226 8697196 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 19.0416870215
MESH:D006930 Hyperalgesia Ethanol 19.0418783367
MESH:D006930 Hyperalgesia Indomethacin 19.0412727271
MESH:D006930 Hyperalgesia rosiglitazone 19.0412083418
MESH:D006930 Hyperalgesia Tretinoin 19.0416870215
MESH:D034321 Hyperamylasemia Indomethacin 5.0617883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.8916899240
MESH:D006937 Hypercholesterolemia Dietary Fats 7.3021332399
MESH:D006937 Hypercholesterolemia resveratrol 7.3017188708
MESH:D006940 Hyperemia Indomethacin 4.3612524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 3.9416778211
MESH:D006943 Hyperglycemia pirinixic acid 7.3820558911
MESH:D006943 Hyperglycemia Quercetin 7.3811834736 18262572
MESH:D020138 Hyperhomocysteinemia Catechin 4.4317292331
MESH:D006949 Hyperlipidemias Dietary Fats 12.0921332399
MESH:D006949 Hyperlipidemias Indomethacin 12.0917546600
MESH:D006949 Hyperlipidemias resveratrol 12.0916873680
MESH:D006967 Hypersensitivity Butylated Hydroxytoluene 3.9517604070
MESH:D006973 Hypertension Dexamethasone 6.9817042910
MESH:D006973 Hypertension Quercetin 6.9818356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 6.9818850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.4615338365
MESH:D006984 Hypertrophy Isoproterenol 4.6112791704
MESH:D017379 Hypertrophy, Left Ventricular phenylmethylpyrazolone 8.9115824197
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 8.9117488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.1816945680 16569931
MESH:D007022 Hypotension Isoproterenol 4.216740701
MESH:D007077 Ileal Diseases 1-Methyl-3-isobutylxanthine 10.5518306037
MESH:D007077 Ileal Diseases Indomethacin 10.5518306037 10574470
MESH:D007079 Ileitis Indomethacin 4.7110647630 16133968 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.7216133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0217600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 2.8712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 8.5817937319
MESH:D007248 Infertility, Male sodium arsenite 8.5812646999 15346721
MESH:D007248 Infertility, Male vinclozolin 8.5816467254
MESH:D007249 Inflammation Dexamethasone 22.058960868 11099482
MESH:D007249 Inflammation Dietary Fats 22.0520412841
MESH:D007249 Inflammation Indomethacin 22.0512568917 3291741 7812673
MESH:D007249 Inflammation Mustard Gas 22.058975870 9357497 9260866 11428647 11428620 11402378 17524151 11428631 16001271
MESH:D007249 Inflammation resveratrol 22.0516366677
MESH:D007249 Inflammation rosiglitazone 22.0512083418
MESH:D007249 Inflammation Sulindac 22.053291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 22.0512200463 12878042
MESH:D007251 Influenza, Human Quercetin 9.0316624496
MESH:D007251 Influenza, Human resveratrol 9.0316624496
MESH:D007333 Insulin Resistance Dietary Fats 14.0018457598 11836018
MESH:D007333 Insulin Resistance Estradiol 14.0016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 14.0016306350
MESH:D007333 Insulin Resistance rosiglitazone 14.0016306350
MESH:D007410 Intestinal Diseases Indomethacin 18.4117994277 11713966 11855677 17329856 11686837 15831440 10210152 15610444 18236018
MESH:D007410 Intestinal Diseases pimagedine 18.4111713966
MESH:D007410 Intestinal Diseases rofecoxib 18.4115831440
MESH:D007410 Intestinal Diseases Tretinoin 18.4117994277
MESH:D007414 Intestinal Neoplasms Sulindac 4.0712351151 12628509 10223192 12584176 10213222 12663524
MESH:D007417 Intestinal Polyps rofecoxib 9.6511245490
MESH:D007417 Intestinal Polyps Sulindac 9.6512394442 11245490
MESH:D002532 Intracranial Aneurysm phenylmethylpyrazolone 4.7219381132
MESH:D019586 Intracranial Hypertension Indomethacin 4.7215241188
MESH:D007511 Ischemia phenylmethylpyrazolone 4.9216301206
MESH:D007569 Jaw Abnormalities Ethanol 13.8415513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 13.8416580747
MESH:D007569 Jaw Abnormalities Tretinoin 13.8415992940 17551590
MESH:D007579 Jejunal Diseases 1-Methyl-3-isobutylxanthine 10.5518306037
MESH:D007579 Jejunal Diseases Indomethacin 10.5516133968 10574470 18306037
MESH:D007627 Keloid Quercetin 4.3317086741
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.0016144296
MESH:D007674 Kidney Diseases Acetaminophen 18.6315629191 12587719
MESH:D007674 Kidney Diseases Estradiol 18.6315618244
MESH:D007674 Kidney Diseases Indomethacin 18.6317190690
MESH:D007674 Kidney Diseases phenylmethylpyrazolone 18.6318085390
MESH:D007674 Kidney Diseases Quercetin 18.6316962696
MESH:D007674 Kidney Diseases sodium arsenite 18.6320008137
MESH:D007680 Kidney Neoplasms Estradiol 5.7415610895
MESH:D007680 Kidney Neoplasms Fluorouracil 5.7416985049
MESH:D007859 Learning Disorders Ethanol 3.5915451040
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.3812228301 11703811 10320625
MESH:D007938 Leukemia arsenic trioxide 8.4115070760
MESH:D007938 Leukemia Quercetin 8.4117468513
MESH:D007938 Leukemia Tretinoin 8.4117143497
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Mitoxantrone 3.4818172266
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.2212560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.6716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 6.9214633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 6.9210785260 16572323 15631656
MESH:D007951 Leukemia, Myeloid arsenic trioxide 12.8719077051
MESH:D007951 Leukemia, Myeloid Retinoids 12.8716482212
MESH:D007951 Leukemia, Myeloid Tretinoin 12.8716482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 5.2220471514 16467208 16968895 17050201 19850784
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 5.2218360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 5.2216294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 10.1911468182 15622746 19075265 11161223 17712046 12679006 16112521 17869043 15336539 12018890 16891316 17649720 17107899 16966277 15748426 17217047 15213294 16823087 12712474 19225113 16330433 19035177 19642359 16331271 9834237
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 10.1916087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 10.1917712046 16766008 19642359 16140955 16891316 16331271 9834237 17368321 17107899 19225113 17339181 15748426 17649720 16788101 17361223 17301526 19035177 17294898 19075265 19029980 17217047 16823087 12679006 16935935 17506722
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.7416882451
MESH:D007964 Leukocytosis Indomethacin 4.7216537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.0617980183
MESH:D007984 Leydig Cell Tumor vinclozolin 4.0916417039
MESH:D017880 Limb Deformities, Congenital Ethanol 6.7217676605
MESH:D017880 Limb Deformities, Congenital Tretinoin 6.729224671
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.0611479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 12.5617174718 16943688 21278145 17157831 11903743 11408273 17334410 16239168 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 12.5618296743
MESH:D008103 Liver Cirrhosis Ethanol 12.5615289165
MESH:D008103 Liver Cirrhosis Phenobarbital 12.5621047994
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.4518295389
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.7912468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 20.5118412020 18187930 12445418 17976157 18210741 15650968 15362042 12666154 16015684 17823541 15818738 18205269 17761835 12389079 15673190 16033810 17869086 13678700 18395914 17900296 12632514 17698563 18339082 17766677 18277467 18006644 18251166 18481824 17714472 12958196 12586293 16097048 15338365 15370692 14748882 14620537 17481882 11481614 12898905 10355542 12741479 15057751 15730626 18166357 16136751 18279442 15996030 18156304 18429990 14716496 18376398 15893842 12546737 20821823 16027843 16116963 17557913 15052691 12649538 18705752 18472332 15925388 16248980 15959796 17708605 14512876 15931870 17565644 17805973 17640975 15123356 12445421 17922224 17721639 18472094 14716833 16638106 18263696 15876570 16192424 12632512 17944888 17631135 18418968 18317297 17525996 12667390 12609069 18395095 18054572 18420326 14724832 16011737
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 20.5116718785
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 20.5117481882
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 20.5114716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 20.5118166357
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 20.5118194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 20.5115474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 20.5112741479
MESH:D008106 Liver Cirrhosis, Experimental rofecoxib 20.5117565644
MESH:D008106 Liver Cirrhosis, Experimental rosiglitazone 20.5117347453 15980055
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 20.5112878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 20.5118397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 7.6019014921 19784758 19460945 11587558 12969438 12587719 16610002 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 7.6015830285 15720792 16246199 17285989 16964402
MESH:D008107 Liver Diseases Phenobarbital 7.6019363144
MESH:D008107 Liver Diseases Sulindac 7.6014986274 16867024
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.0317347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5415123358
MESH:D017114 Liver Failure, Acute Acetaminophen 7.5417185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 7.5416899240 14706259
MESH:D008113 Liver Neoplasms arsenic trioxide 31.6614682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 31.6621137059 20195826
MESH:D008113 Liver Neoplasms Butylated Hydroxytoluene 31.6618177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 31.6619294768
MESH:D008113 Liver Neoplasms Fluorouracil 31.6615113037 17045692 18383874 16603448
MESH:D008113 Liver Neoplasms Phenobarbital 31.6621047994 19812893 19073162 19482888 15975961 8742319
MESH:D008113 Liver Neoplasms pirinixic acid 31.6620007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 31.6618980244
MESH:D008113 Liver Neoplasms resveratrol 31.6619073162 20405173 19812893 19321006
MESH:D008113 Liver Neoplasms sodium arsenite 31.6615276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 31.6616984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 14.1020377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.1012014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 14.1018308698 2563599 6150874 17172636 1399818
MESH:D008114 Liver Neoplasms, Experimental Quercetin 14.1019519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.1012151625
MESH:D008133 Long QT Syndrome arsenic trioxide 2.8515213294
MESH:D008171 Lung Diseases Mustard Gas 9.7618702808 18161513
MESH:D008171 Lung Diseases Ozone 9.7619066396 8266340
MESH:D008171 Lung Diseases sodium arsenite 9.7619095001
MESH:D055370 Lung Injury Ozone 3.2320417186
MESH:D008175 Lung Neoplasms alitretinoin 28.0416413115
MESH:D008175 Lung Neoplasms arsenic trioxide 28.0419825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 28.0420869020 20464547 20135361 18816296 20064080 17053015 18520028 18569708 6695378
MESH:D008175 Lung Neoplasms bexarotene 28.0417849452
MESH:D008175 Lung Neoplasms Butylated Hydroxytoluene 28.0419925653 11696405 11246140 18597497 15390079 19359593 16337739
MESH:D008175 Lung Neoplasms Dexamethasone 28.0411195469 15824018
MESH:D008175 Lung Neoplasms Fluorouracil 28.0415246190
MESH:D008175 Lung Neoplasms Indomethacin 28.0416537180 11497255 11053908
MESH:D008175 Lung Neoplasms Isotretinoin 28.0415899809
MESH:D008175 Lung Neoplasms Mustard Gas 28.048781369 3148597
MESH:D008175 Lung Neoplasms Ozone 28.048597069 7614698
MESH:D008175 Lung Neoplasms Quercetin 28.0416280456
MESH:D008175 Lung Neoplasms sodium arsenite 28.0417306315 17077188 16712894 15276417 19931552
MESH:D008175 Lung Neoplasms Sulindac 28.0419359593 15713900
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 28.0419555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.1515086387
MESH:D016393 Lymphoma, B-Cell resveratrol 3.7117088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.3414749477
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.5211161223
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.6115688416
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 14.2119196722 15591091 19196723
MESH:D008325 Mammary Neoplasms, Experimental Butylated Hydroxytoluene 14.211500032
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 14.2116891317 11807958 17203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 14.2111606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental rosiglitazone 14.2116827153
MESH:D020149 Manganese Poisoning Estradiol 3.8319453300
MESH:D008415 Mastocytosis Retinoids 5.9416953078
MESH:D008527 Medulloblastoma Tretinoin 2.4917453147
MESH:D008545 Melanoma epigallocatechin gallate 10.4211746506 17992120
MESH:D008545 Melanoma Isotretinoin 10.4217237267
MESH:D008545 Melanoma resveratrol 10.4217992120
MESH:D008545 Melanoma sodium arsenite 10.4219082730 16487513
MESH:D008545 Melanoma Sulindac 10.4216642371
MESH:D008545 Melanoma Tretinoin 10.4216752155
MESH:D008546 Melanoma, Experimental Acetaminophen 2.9419513568
MESH:D008569 Memory Disorders Ethanol 3.5818411066 15451040
MESH:D008591 Meningomyelocele Tretinoin 3.8016940565
MESH:D008659 Metabolic Diseases phenylmethylpyrazolone 9.1216301206
MESH:D008659 Metabolic Diseases resveratrol 9.1217112576
MESH:D024821 Metabolic Syndrome X rosiglitazone 3.8417261469
MESH:D008679 Metaplasia Ozone 4.4510496685
MESH:D008881 Migraine Disorders Indomethacin 3.2011903285
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 11.5016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 11.5016757204 18986760
MESH:D009062 Mouth Neoplasms Indomethacin 11.5012636206
MESH:D052016 Mucositis irinotecan 4.3717159606
MESH:D009101 Multiple Myeloma arsenic trioxide 9.4415949261 11468182 19417148 19549372 14977855
MESH:D009101 Multiple Myeloma Dexamethasone 9.4416118317 15867202 15744524
MESH:D009101 Multiple Myeloma resveratrol 9.4417049120 17164350 16490592 17935668 16267019 14749477
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 10.4917962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.4917962980
MESH:D009135 Muscular Diseases pirinixic acid 2.8816239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.0218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.0216882451 16105982
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 10.029809623
MESH:D009190 Myelodysplastic Syndromes Tretinoin 10.0217596541
MESH:D009203 Myocardial Infarction Isoproterenol 11.0215740881 19595682 16584858 16697266 19172585 17052832 16538859
MESH:D009203 Myocardial Infarction pirinixic acid 11.0219151258
MESH:D009203 Myocardial Infarction Quercetin 11.0219595682
MESH:D009203 Myocardial Infarction resveratrol 11.0216525036 17015251 16456233 17125593 17188708 16317513
MESH:D017202 Myocardial Ischemia resveratrol 7.2817125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.2812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 11.2616810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 11.2616411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 11.2619207477
MESH:D009205 Myocarditis resveratrol 4.1217322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 3.8317484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.3516624393
MESH:D009362 Neoplasm Metastasis Indomethacin 5.1711239499 11053908 16537180
MESH:D009362 Neoplasm Metastasis irinotecan 5.1718259882
MESH:D009369 Neoplasms alitretinoin 22.0616946489
MESH:D009369 Neoplasms Benzo(a)pyrene 22.0611141357
MESH:D009369 Neoplasms Fluorouracil 22.0618239605 16928823 18600527
MESH:D009369 Neoplasms Mitoxantrone 22.0616640825
MESH:D009369 Neoplasms pirinixic acid 22.0617405874
MESH:D009369 Neoplasms Quercetin 22.0615185748
MESH:D009369 Neoplasms sodium arsenite 22.0611559025
MESH:D009369 Neoplasms Tretinoin 22.0616946489 16594593
MESH:D009374 Neoplasms, Experimental Indomethacin 11.7615625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 11.768985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 11.7620056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.1319196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.1017289903
MESH:D009421 Nervous System Malformations Estradiol 12.8116427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 12.8114600291
MESH:D009421 Nervous System Malformations Tretinoin 12.819125849
MESH:D009436 Neural Tube Defects arsenic trioxide 9.5710525206
MESH:D009436 Neural Tube Defects sodium arsenite 9.5712854658
MESH:D009436 Neural Tube Defects Tretinoin 9.579142499
MESH:D009447 Neuroblastoma irinotecan 6.208761367
MESH:D009447 Neuroblastoma Isotretinoin 6.2017368321
MESH:D019636 Neurodegenerative Diseases Acetaminophen 15.8018514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 15.8012349958
MESH:D019636 Neurodegenerative Diseases resveratrol 15.8017652729
MESH:D019636 Neurodegenerative Diseases Sulindac 15.8016850258 17266991
MESH:D017599 Neuroectodermal Tumors irinotecan 4.098761367
MESH:D020078 Neurogenic Inflammation Quercetin 8.7217929310
MESH:D020078 Neurogenic Inflammation resveratrol 8.7217929310
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 7.0216436463
MESH:D020258 Neurotoxicity Syndromes Malathion 7.0215081274
MESH:D009503 Neutropenia Mustard Gas 3.3816761898 7688884
MESH:D009765 Obesity Dietary Fats 3.7411836018 20132043 17217161 19632207 20518802 18674790 18457598 16723640 21332399
MESH:D009765 Obesity pirinixic acid 3.7420558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.516374098
MESH:D010003 Osteoarthritis Indomethacin 6.747009135
MESH:D010003 Osteoarthritis rofecoxib 6.7416690336
MESH:D010018 Osteomalacia Phenobarbital 3.7217016548
MESH:D010024 Osteoporosis Levonorgestrel 4.2412665316
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.2319495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.2317513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 15.5512452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 15.5519401270
MESH:D010051 Ovarian Neoplasms Mifepristone 15.5516525653
MESH:D010051 Ovarian Neoplasms Quercetin 15.5519005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 15.5517306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 15.5516936753
MESH:D010146 Pain Acetaminophen 11.8516870215
MESH:D010146 Pain Indomethacin 11.8513679232 17627676 17440234 3291741
MESH:D010146 Pain Sulindac 11.853291741
MESH:D010146 Pain Tretinoin 11.8516870215
MESH:D010149 Pain, Postoperative Indomethacin 9.4018702446 12538197
MESH:D010149 Pain, Postoperative rofecoxib 9.4018165598 16678543
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 20.5515580305
MESH:D010190 Pancreatic Neoplasms Ethanol 20.5512384795
MESH:D010190 Pancreatic Neoplasms Fluorouracil 20.5516500647 16929163 15113037 19003803
MESH:D010190 Pancreatic Neoplasms Phenobarbital 20.5516965848
MESH:D010190 Pancreatic Neoplasms Quercetin 20.5516965848
MESH:D010190 Pancreatic Neoplasms Sulindac 20.5516820089 11504793
MESH:D010190 Pancreatic Neoplasms Tretinoin 20.5515976015
MESH:D010195 Pancreatitis Indomethacin 7.1315028970 17883296
MESH:D010195 Pancreatitis phenylmethylpyrazolone 7.1320035747
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.0911578682
MESH:D010235 Paraganglioma arsenic trioxide 3.5719927285
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.0616537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.5612349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.0611903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.5912520081
MESH:D010437 Peptic Ulcer Indomethacin 4.5111148446
MESH:D010518 Periodontitis Indomethacin 4.2617225004
MESH:D010538 Peritonitis Ozone 3.5116369182
MESH:D011014 Pneumonia Butylated Hydroxytoluene 9.2011893704
MESH:D011014 Pneumonia Ozone 9.2018381685 18929643 18007984
MESH:D011041 Poisoning Mustard Gas 3.2115727166
MESH:D011085 Polycystic Ovary Syndrome ethinyl estradiol-desogestrel combination 5.0317105841
MESH:D017499 Porokeratosis alitretinoin 5.3516144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9518163543
MESH:D011230 Precancerous Conditions Phenobarbital 7.432563599
MESH:D011230 Precancerous Conditions Quercetin 7.4319056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.1521297632
MESH:D047928 Premature Birth Indomethacin 4.5017000239
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 18.0718769834
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 18.0716679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 18.0711118676 11222880 11896295 11399792
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 18.0718042343 19015723 18220299
MESH:D011469 Prostatic Diseases vinclozolin 4.2918220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.3120887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6219131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.6217292933
MESH:D011471 Prostatic Neoplasms Cholecalciferol 2.6217024972
MESH:D011471 Prostatic Neoplasms Estradiol 2.6216740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.6218626508 19082440
MESH:D011471 Prostatic Neoplasms Quercetin 2.6217292933 14715546
MESH:D011471 Prostatic Neoplasms resveratrol 2.6217636462 15767336 17718901 17675339 17804756 16731767
MESH:D011471 Prostatic Neoplasms Retinoids 2.6216724957 16166285
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.6216039940
MESH:D011472 Prostatitis vinclozolin 4.2918629315
MESH:D011507 Proteinuria Indomethacin 7.3711849393
MESH:D011507 Proteinuria Tretinoin 7.3716636307
MESH:D011537 Pruritus Ethinyl Estradiol 12.6316919318 15861022
MESH:D011537 Pruritus Levonorgestrel 12.6315861022
MESH:D011537 Pruritus Mustard Gas 12.6318058305
MESH:D019310 Pseudolymphoma Phenobarbital 3.8412752131
MESH:D011596 Psychomotor Disorders Isotretinoin 5.2818769834
MESH:D011625 Pterygium Tretinoin 4.1516723453
MESH:D011654 Pulmonary Edema Isoproterenol 4.6010903255
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.6517894541 17620002 17266442 10334151 17720292
MESH:D012004 Rectal Neoplasms Fluorouracil 3.4618286688 15538739 16160472 18722050
MESH:D051436 Renal Insufficiency, Chronic resveratrol 4.9316325855
MESH:D015427 Reperfusion Injury phenylmethylpyrazolone 9.0415086910 15948865 14654979 16041266 15629865 16753835
MESH:D015427 Reperfusion Injury pirinixic acid 9.0419058328
MESH:D015427 Reperfusion Injury resveratrol 9.0417520802 16314181 15827377 17058453 16317513
MESH:D012120 Respiration Disorders Chlorine 4.5618579056
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 3.4318379247 11700416
MESH:D012135 Respiratory Sounds Malathion 4.6517119214 11874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2318990726
MESH:D012140 Respiratory Tract Diseases Malathion 4.8817119214
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.5116283617 16116481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.5616646077
MESH:D012512 Sarcoma, Ewing's Dactinomycin 8.5614601052
MESH:D012554 Schistosomiasis japonica Quercetin 4.8916862918
MESH:D012640 Seizures Ethanol 4.669754883
MESH:D012640 Seizures Phenobarbital 4.663137016 4039156 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.186407741
MESH:D012871 Skin Diseases Mustard Gas 2.5215451306 12880345 16961503
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 17.9810029692 19755658
MESH:D012878 Skin Neoplasms resveratrol 17.9815837718 8985016
MESH:D012878 Skin Neoplasms Retinoids 17.9817538947
MESH:D012878 Skin Neoplasms sodium arsenite 17.9818572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 17.9816192470
MESH:D012878 Skin Neoplasms Tretinoin 17.9816467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.2916709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.2912854658
MESH:D013272 Stomach Diseases Dexamethasone 8.2515472012
MESH:D013272 Stomach Diseases Indomethacin 8.2518545984 15038085 10192188 10215738 18209964 10486359 16184426 15472012 16113693 17160473 17207306 16280098 17638125
MESH:D013274 Stomach Neoplasms arsenic trioxide 8.8817007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 8.882093021 20155912
MESH:D013274 Stomach Neoplasms Ethanol 8.8818456281
MESH:D013274 Stomach Neoplasms Fluorouracil 8.8817172411 16951190 18567086 18396642 17498489 16424979 17522103 19015929 19084572 15786421
MESH:D013274 Stomach Neoplasms Indomethacin 8.8815609394
MESH:D013274 Stomach Neoplasms irinotecan 8.8815723263
MESH:D013274 Stomach Neoplasms Tretinoin 8.8817261132
MESH:D013276 Stomach Ulcer Dexamethasone 12.6215138204
MESH:D013276 Stomach Ulcer Ethanol 12.6217189318 9562338 11906479 16755016 17918041 9211565
MESH:D013276 Stomach Ulcer Indomethacin 12.6217657623 17627676 17977527 11523592 10750652 12498302 16631530 18209962 1323529 11729361 11906479 18299717 18543354 15255614 12077510 18726076 18193104 11595415 16169175 18087811 15138204 11595431 17918041 17654042 16934674 16252198 16397915 16755016 10878458 18181030 10423059 12467913 16150113 15104355 17895592 14567935 17135157 18237397 12787963 11145282 12500499 18431645
MESH:D013276 Stomach Ulcer pimagedine 12.6218209962
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9116321402
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.699754883
MESH:D019851 Thrombophilia Ethinyl Estradiol 15.0411994571
MESH:D019851 Thrombophilia ethinyl estradiol-desogestrel combination 15.0411994571
MESH:D019851 Thrombophilia Gestodene 15.0411994571
OMIM:612348 THROMBOPHILIA, FAMILIAL, DUE TO DECREASED RELEASE OF TISSUE PLASMINOGEN ACTIVATOR marker/mechanism
MESH:D013927 Thrombosis therapeutic 19348381
MESH:D013927 Thrombosis Ethinyl Estradiol 7.7315669648
MESH:D013927 Thrombosis Gestodene 7.7315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 17.2219014326
MESH:D013964 Thyroid Neoplasms Indomethacin 17.2211352223 14736730 18791128
MESH:D013964 Thyroid Neoplasms Phenobarbital 17.221399818
MESH:D013964 Thyroid Neoplasms Retinoids 17.2216940797
MESH:D013964 Thyroid Neoplasms Tretinoin 17.2217045167 16026305
MESH:D013978 Tibial Fractures Estradiol 4.0319048282
MESH:D014062 Tongue Neoplasms Fluorouracil 13.3316280240
MESH:D014062 Tongue Neoplasms resveratrol 13.3316227395
MESH:D014062 Tongue Neoplasms Tretinoin 13.3316051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.3215213294
MESH:D014376 Tuberculosis Tretinoin 2.8016040207
MESH:D014456 Ulcer Indomethacin 4.2510574470 17380554
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 9.4612845720 20435036 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 9.4617053015
MESH:D001749 Urinary Bladder Neoplasms Quercetin 9.4616720314
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 9.4611723127 17306315 16712894 16452187
MESH:D014581 Urticaria Acetaminophen 2.3910982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 18.0316803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 18.0317473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 18.0311813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 18.0316129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 12.6314692618
MESH:D014594 Uterine Neoplasms resveratrol 12.6317044934
MESH:D014594 Uterine Neoplasms Sulindac 12.6318645019
MESH:D014604 Uveal Neoplasms Tretinoin 3.9616752155
MESH:D014605 Uveitis Dexamethasone 4.161336536
MESH:D014652 Vascular Diseases sodium arsenite 3.7817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9412125929
MESH:D020301 Vasospasm, Intracranial therapeutic 19057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 14.5915869587 14671159
MESH:D020246 Venous Thrombosis ethinyl estradiol-desogestrel combination 14.5915869587
MESH:D020246 Venous Thrombosis Levonorgestrel 14.5915869587
MESH:D018487 Ventricular Dysfunction, Left Isoproterenol 8.6018097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.6017488730
MESH:D020257 Ventricular Remodeling Isoproterenol 5.0518097624
MESH:D014820 Vitiligo Tretinoin 3.4516761959
MESH:D014839 Vomiting Indomethacin 4.0911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.5915886252
MESH:D015430 Weight Gain Dietary Fats 3.1916723640
MESH:D009396 Wilms Tumor Tretinoin 3.4216287080
Pathway ID Pathway Name
KEGG:04610 Complement and coagulation cascades
REACT:604 Hemostasis
REACT:16888 Signaling by PDGF
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33381
    • No data
    Releated disease ID Related disease Name
    PA443635Cardiovascular Diseases
    Releated drug ID Related drug Name
    PA449470epinephrine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00013 - Urokinase Thrombolytic Agents
    DB00513 antagonist Aminocaproic Acid Antifibrinolytic Agents
    DB01088 other/unknown Iloprost Antihypertensive Agents
    DB04134 - 6-Amino Hexanoic Acid Antifibrinolytic Agents
    DB07684 - 5-(DIMETHYLAMINO)-2-NAPHTHALENESULFONIC ACID
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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