AutismKB 2.0

Annotation Detail for PLXNB3


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Basic Information Top
Gene Symbol:PLXNB3 ( FLJ76953,PLEXB3,PLEXR,PLXN6 )
Gene Full Name: plexin B3
Band: Xq28
Quick LinksEntrez ID:5365; OMIM: 300214; Uniprot ID:PLXB3_HUMAN; ENSEMBL ID: ENSG00000198753; HGNC ID: 9105
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04360Axon guidance
Pathway IDPathway Name
Axon guidance
No data
No data
Pathway IDPathway Name
500078Other semaphorin interactions
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C015001 arsenite arsenite results in decreased expression of PLXNB3 mRNAdecreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in decreased expression of PLXNB3 mRNA]affects reaction|decreases expression 18929588
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D003110 Colonic Neoplasms arsenite 2.6515037631
MESH:D005234 Fatty Liver arsenite 4.4018296743
MESH:D005355 Fibrosis arsenite 4.9718296743
MESH:D008103 Liver Cirrhosis arsenite 3.6718296743
MESH:D008175 Lung Neoplasms arsenite 2.3616809336
MESH:D009389 Neovascularization, Pathologic arsenite 5.5015738583
Pathway ID Pathway Name
KEGG:04360 Axon guidance
REACT:18266 Axon guidance
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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