Annotation Detail for IL20RB
Basic Information Top
| Gene Symbol: | IL20RB ( DIRS1,FNDC6,IL-20R2,MGC34923 ) |
|---|---|
| Gene Full Name: | interleukin 20 receptor beta |
| Band: | 3q22.3 |
| Quick Links | Entrez ID:53833; OMIM: 605621; Uniprot ID:I20RB_HUMAN; ENSEMBL ID: ENSG00000174564; HGNC ID: 6004 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of IL20RB mRNA | affects expression | 17562736 |
| D016572 | Cyclosporine | Cyclosporine results in increased expression of IL20RB mRNA | increases expression | 20106945 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Cyclosporine | 2.85 | 12371664 | |
| MESH:D002779 | Cholestasis | Cyclosporine | 3.28 | 19486331 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 17522070 14550746 16109766 16393943 11421492 10663392 11287661 12153990 18071297 11743745 19739265 16485898 11834606 2444490 10915739 12392966 17906064 11739529 16081117 10774834 16227642 11529661 15968718 12540782 19085960 17562736 12958197 19370779 14986274 12594235 16177239 19420014 12705907 18713872 14725611 19164858 16781746 19923254 15619225 19416960 11461765 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005234 | Fatty Liver | Cyclosporine | 3.40 | 19224547 | |
| MESH:D005355 | Fibrosis | Cyclosporine | 3.90 | 12639820 12168785 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D005885 | Gingival Hyperplasia | Cyclosporine | 5.11 | 8708960 | |
| MESH:D006457 | Hemoglobinuria, Paroxysmal | Cyclosporine | 5.31 | 15720958 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D006973 | Hypertension | Cyclosporine | 2.24 | 10903974 | |
| MESH:D007638 | Keratoconjunctivitis Sicca | Cyclosporine | 5.51 | 15604871 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 6.63 | 12587719 15629191 | |
| MESH:D007674 | Kidney Diseases | Cyclosporine | 6.63 | 18776723 10903974 8314463 | |
| MESH:D007680 | Kidney Neoplasms | Cyclosporine | 3.17 | 12371664 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16610002 12969438 16611625 19784758 12587719 19460945 11587558 19014921 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D008664 | Metal Metabolism, Inborn Errors | Cyclosporine | 5.86 | 16801185 | |
| MESH:D009402 | Nephrosis, Lipoid | Cyclosporine | 5.51 | 17954296 | |
| MESH:D009404 | Nephrotic Syndrome | Cyclosporine | 3.75 | 19348381 18481113 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D011230 | Precancerous Conditions | Cyclosporine | 3.69 | 12371664 | |
| MESH:D011565 | Psoriasis | Cyclosporine | 2.35 | 16882103 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 | |
| MESH:D014605 | Uveitis | Cyclosporine | 5.05 | 1336536 | |
| MESH:D014985 | Xerophthalmia | Cyclosporine | 5.51 | 17120751 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04060 | Cytokine-cytokine receptor interaction |
| KEGG:04630 | Jak-STAT signaling pathway |