AutismKB 2.0

Annotation Detail for POLD2


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Basic Information Top
Gene Symbol:POLD2 ( - )
Gene Full Name: polymerase (DNA directed), delta 2, regulatory subunit 50kDa
Band: 7p13
Quick LinksEntrez ID:5425; OMIM: 600815; Uniprot ID:DPOD2_HUMAN; ENSEMBL ID: ENSG00000106628; HGNC ID: 9176
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa00240Pyrimidine metabolism
hsa03440Homologous recombination
hsa03030DNA replication
hsa03420Nucleotide excision repair
hsa00230Purine metabolism
hsa03410Base excision repair
hsa01100Metabolic pathways
hsa03430Mismatch repair
Pathway IDPathway Name
Cell Cycle, Mitotic
DNA Replication
Chromosome Maintenance
DNA Repair
No data
Pathway IDPathway Name
P00017DNA replication
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of POLD2 mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of POLD2 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of POLD2 mRNAaffects expression 17562736
C030123 coumarin coumarin results in increased expression of POLD2 mRNAincreases expression 18480146
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of POLD2 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of POLD2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLD2 mRNAaffects cotreatment|increases expression 17942748
D008628 Mercury Mercury affects the expression of POLD2 mRNAaffects expression 16823088
D015735 Mifepristone Mifepristone results in decreased expression of POLD2 mRNAdecreases expression 17584828
C006253 pirinixic acid pirinixic acid results in decreased expression of POLD2 mRNAdecreases expression 18445702
C006253 pirinixic acid pirinixic acid results in increased expression of POLD2 mRNAincreases expression 17950772
18301758
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of POLD2 mRNA]increases expression|increases reaction 17950772
D011794 Quercetin Quercetin results in decreased expression of POLD2 mRNAdecreases expression 15309432
D013629 Tamoxifen Tamoxifen affects the expression of POLD2 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POLD2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of POLD2 mRNAincreases expression 17942748
D014212 Tretinoin Tretinoin results in decreased expression of POLD2 mRNAdecreases expression 18230668
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.7214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0011752688 14514962 15322242
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.1217505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.2318653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8314692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.813712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.4216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.4216835633
MESH:D000505 Alopecia Tretinoin 3.7015955085
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0511748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.3517084956
MESH:D000799 Angioedema Acetaminophen 4.0210982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.6011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.4215885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.4216412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2916292516
MESH:D001249 Asthma Tretinoin 2.3716456186
MESH:D001260 Ataxia Telangiectasia Quercetin 5.1315336622
MESH:D001321 Autistic Disorder Acetaminophen 2.1418445737
MESH:D001321 Autistic Disorder Mercury 2.1417497416
MESH:D001327 Autoimmune Diseases Mercury 11.4816634805
MESH:D001327 Autoimmune Diseases Quercetin 11.4819761891
MESH:D001471 Barrett Esophagus Tretinoin 4.5316935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.1911289319 1440618
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.9319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.9312125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 15.9316206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.9615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8315746008
MESH:D001943 Breast Neoplasms Quercetin 1.9718628248
MESH:D001943 Breast Neoplasms Tamoxifen 1.9719084267 17049068 16202921 16818667 18629630 21138602 19142967 18984771 15565566 20005174 15668708 20390343 20135344 16873071 19244106 20065188 19189212 19066611 19059307 21152245 19155303 20544844 17893378 19289846 19011961 17261762 11161223 19288272 19221464 19103187 18815881 19200415 16273361 17440819 18855134 18425577 18351453 18821012 19189210 18997820 19115204 19410462 19487384 17242785 20859285
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9720435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9716166294 16873071 16443354
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7416813970
MESH:D002105 Cadmium Poisoning Quercetin 5.7216962696
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.6419066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.3316168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.6116705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.613581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.613084413
MESH:D006528 Carcinoma, Hepatocellular Quercetin 11.6112508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.6116924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 11.611917145
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 5.0917234771
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.727296757
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.3216096774 16051514
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.7217572228
MESH:D006332 Cardiomegaly Quercetin 6.9919794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.9918670907 16120746 18850075
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.4810334427
MESH:D002386 Cataract Acetaminophen 7.4310977129
MESH:D002386 Cataract Tretinoin 7.4317460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.837505956
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7416129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2616835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.859022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.8517333356 17681005 11677210 16919318 17110522 16105132 15861022
MESH:D002779 Cholestasis pirinixic acid 13.8519176532
MESH:D002822 Choriocarcinoma Tretinoin 5.3316461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.9015668235 8697196 16354765 15340226 12621046
MESH:D002972 Cleft Palate Tretinoin 5.909407595
MESH:D003092 Colitis Tretinoin 3.8417035595
MESH:D003110 Colonic Neoplasms Quercetin 2.4316640504 17191121 17148506 11134977 19440933 19056647 15741050
MESH:D015179 Colorectal Neoplasms Quercetin 2.1918852136 18095365
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1614669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4810048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.489125849 16925845 8800419 10589399 9224671 17551590 9142499 14991402 9211117 9664655
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.1518551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.5019031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 7.6518759878 2524372 14531868 11906362 8156756 8970840 12868966 11298694
MESH:D017449 Dermatitis, Allergic Contact Mercury 7.6516823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4718249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.613621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.8219496084
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 4.6719647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.6717107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5719279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.1918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 9.191440618 11289319 16192314 9328219 18692083 18289764 9022650 6482804 8291058 9653073 18648102 6679447 7440962
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.1916781746 19416960 12392966 16227642 17562736 2444490 12705907 16177239 11529661 11834606 16485898 11287661 11743745 17906064 11739529 19085960 19420014 19739265 19370779 12958197 10663392 10915739 14725611 19923254 14550746 17522070 18713872 15968718 15619225 11421492 10774834 16109766 12540782 12594235 12153990 18071297 16393943 11461765 19164858 14986274 16081117
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.1920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8411462148
MESH:D004487 Edema pirinixic acid 6.9012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.9012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 12.5316714409 15322242 18230668
MESH:D004489 Edema, Cardiac Tretinoin 12.5318230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.3712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.3719031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.6719155303 20544844 16202921 17893378
MESH:D016889 Endometrial Neoplasms Tretinoin 7.6716569247
MESH:D004715 Endometriosis Mifepristone 9.5016134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 9.509294722 10568697
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.133581430
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 9.1111564622
MESH:D005124 Eye Abnormalities Tretinoin 9.1116938888 9664655
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.6915345470
MESH:D005234 Fatty Liver pirinixic acid 13.6920131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 13.6914986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.3016709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5911858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.196705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.3419069698
MESH:D005355 Fibrosis Quercetin 15.6619474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.6620067830
MESH:D005355 Fibrosis Tretinoin 15.6617994277
MESH:D005756 Gastritis Acetaminophen 3.8516983495
MESH:D005909 Glioblastoma Quercetin 7.4919804834
MESH:D005909 Glioblastoma Tretinoin 7.4917312396
MESH:D005910 Glioma Quercetin 3.0917643826
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.157505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.7710696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.2616096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.3316084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.7211294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 6.7214991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.6020558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4411000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.646705139
MESH:D006529 Hepatomegaly pirinixic acid 8.7316221962 19176532 19772884 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.7315340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.2216959395 18606429 8697196 16354765 15340226
MESH:D006930 Hyperalgesia Acetaminophen 7.9216870215
MESH:D006930 Hyperalgesia Tretinoin 7.9216870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.7116778211
MESH:D006943 Hyperglycemia pirinixic acid 9.5920558911
MESH:D006943 Hyperglycemia Quercetin 9.5911834736 18262572
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0815034207
MESH:D006973 Hypertension Quercetin 5.3518356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.3518670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5617937319
MESH:D007249 Inflammation Tamoxifen 5.0719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.0712878042 12200463
MESH:D007251 Influenza, Human Quercetin 4.6816624496
MESH:D007333 Insulin Resistance pirinixic acid 2.7016306350
MESH:D007410 Intestinal Diseases Tretinoin 3.9017994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.199022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.3016580747
MESH:D007569 Jaw Abnormalities Tretinoin 10.3015992940 17551590
MESH:D007627 Keloid Quercetin 5.0917086741
MESH:D007674 Kidney Diseases Acetaminophen 10.5612587719 15629191
MESH:D007674 Kidney Diseases Mercury 10.5617934191
MESH:D007674 Kidney Diseases Quercetin 10.5616962696
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.9516705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 12.956582329
MESH:D007680 Kidney Neoplasms Tamoxifen 12.9518625569
MESH:D007938 Leukemia Quercetin 6.6317468513
MESH:D007938 Leukemia Tretinoin 6.6317143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.8119285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0917596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2217294898 9834237 16823087 16766008 17649720 15748426 16891316 16331271 19225113 17107899 17301526 17339181 19029980 17368321 16935935 19642359 16140955 19035177 12679006 17712046 17506722 17217047 17361223 19075265 16788101
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.389224671
MESH:D008064 Lipidoses Tamoxifen 3.2315342952 17567588
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2615034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.8615474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 6.8612741479
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.8618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.8612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.8618397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 1.6519784758 16610002 12969438 12587719 16611625 19460945 11587558 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3417185352 16871587
MESH:D008113 Liver Neoplasms pirinixic acid 11.0115890375 20007298 16377806
MESH:D008113 Liver Neoplasms Quercetin 11.0118980244
MESH:D008113 Liver Neoplasms Tamoxifen 11.0116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.0116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 10.233712494 1399818 6587162 598648
MESH:D008114 Liver Neoplasms, Experimental Quercetin 10.2319519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.2312151625
MESH:D008175 Lung Neoplasms Quercetin 3.4916280456
MESH:D008175 Lung Neoplasms Tamoxifen 3.4918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4911884234 19555203
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.9119428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6911731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.7219453300
MESH:D008527 Medulloblastoma Tretinoin 2.8217453147
MESH:D008545 Melanoma Tamoxifen 3.3412393984 19393235
MESH:D008545 Melanoma Tretinoin 3.3416752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.3415990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7119513568
MESH:D008591 Meningomyelocele Tretinoin 4.5616940565
MESH:D009135 Muscular Diseases pirinixic acid 3.6416239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1417596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.8619151258
MESH:D009203 Myocardial Infarction Quercetin 5.8619595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.7216411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.7219207477
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.0118551238
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 5.833581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.8319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5519410462
MESH:D009369 Neoplasms pirinixic acid 8.5817405874
MESH:D009369 Neoplasms Quercetin 8.5815185748
MESH:D009369 Neoplasms Tretinoin 8.5816946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1719200415 19189210 19196722
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.9414600291
MESH:D009421 Nervous System Malformations Tretinoin 9.949125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.466679447
MESH:D009436 Neural Tube Defects Tretinoin 7.469142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9618514411
MESH:D020078 Neurogenic Inflammation Quercetin 4.4817929310
MESH:D009765 Obesity pirinixic acid 1.8420558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.2312819281 16049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.234026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.193988306
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.3419495926
MESH:D010051 Ovarian Neoplasms Mifepristone 8.2216525653
MESH:D010051 Ovarian Neoplasms Quercetin 8.2219005980
MESH:D010051 Ovarian Neoplasms Tretinoin 8.2216936753
MESH:D010146 Pain Acetaminophen 6.8916870215
MESH:D010146 Pain Tretinoin 6.8916870215
MESH:D010190 Pancreatic Neoplasms Quercetin 5.5316965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.5315976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8011578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.627296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4212520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.646228378
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6918163543
MESH:D011230 Precancerous Conditions Quercetin 4.0819056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.3411222880 11118676 11896295 11399792
MESH:D011471 Prostatic Neoplasms Quercetin 3.3414715546 17292933
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.3415067354
MESH:D011507 Proteinuria Tretinoin 3.7216636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.4716919318 15861022
MESH:D011625 Pterygium Tretinoin 4.9516723453
MESH:D015427 Reperfusion Injury pirinixic acid 2.4319058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9618990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.463692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.2216283617 16116481
MESH:D012554 Schistosomiasis japonica Quercetin 5.7216862918
MESH:D012640 Seizures 2,4-dinitrotoluene 2.6018551238
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.7216192470
MESH:D012878 Skin Neoplasms Tretinoin 5.7216467112
MESH:D013088 Spermatocele Ethinyl Estradiol 12.1516709447
MESH:D013088 Spermatocele Tamoxifen 12.1516709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1919457130
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0812697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.416582329 3712494 1399818 6587162 7505956
MESH:D013964 Thyroid Neoplasms Tretinoin 7.4117045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 3.8916051514
MESH:D014376 Tuberculosis Tretinoin 3.2916040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 12.2716049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 12.278074119
MESH:D001749 Urinary Bladder Neoplasms Quercetin 12.2716720314
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 12.2717572228 16712894 8653321
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.4710091137
MESH:D014581 Urticaria Acetaminophen 3.0910982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7816129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.4214692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.7816752155
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.7712125929
MESH:D014689 Venous Insufficiency coumarin 5.9512708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6515869587 14671159
MESH:D014820 Vitiligo Tretinoin 4.1816761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4215886252
MESH:D009396 Wilms Tumor Tretinoin 4.0716287080
Pathway ID Pathway Name
KEGG:03410 Base excision repair
REACT:152 Cell Cycle, Mitotic
REACT:22172 Chromosome Maintenance
REACT:216 DNA Repair
REACT:383 DNA Replication
KEGG:03030 DNA replication
KEGG:03440 Homologous recombination
KEGG:01100 Metabolic pathways
KEGG:03430 Mismatch repair
KEGG:03420 Nucleotide excision repair
KEGG:00230 Purine metabolism
KEGG:00240 Pyrimidine metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33497
    • No data
    Releated disease ID Related disease Name
    PA445742Stomach Neoplasms
    Releated drug ID Related drug Name
    PA449957ibuprofen
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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