AutismKB 2.0

Annotation Detail for POMC


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Basic Information Top
Gene Symbol:POMC ( ACTH,CLIP,LPH,MSH,NPP,POC )
Gene Full Name: proopiomelanocortin
Band: 2p23.3
Quick LinksEntrez ID:5443; OMIM: 176830; Uniprot ID:COLI_HUMAN; ENSEMBL ID: ENSG00000115138; HGNC ID: 9201
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04920Adipocytokine signaling pathway
hsa04916Melanogenesis
Pathway IDPathway Name
Signaling by GPCR
Hormone biosynthesis
Opioid Signalling
Metabolism of amino acids and derivatives
Pathway IDPathway Name
200170Syndecan-3-mediated signaling events
200077Glucocorticoid receptor regulatory network
Pathway IDPathway Name
P04380Cortocotropin releasing factor receptor signaling pathway
Pathway IDPathway Name
500768Peptide hormone biosynthesis
500405Peptide ligand-binding receptors
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1738Cushing syndrome
1770Melanoma
1856Obesity
1870Drug abuse
1884Mesothelioma
1894Abortion
1904Diabetes mellitus
1907Depression
2013Sella turcica tumor
2023Adrenal gland hyperfunction
2044Pre-Eclampsia
2052Infection
2069Schizophrenia
2123Vitiligo
2138Osteoporosis
2230Alopecia
Desease Name
serum leptin levels
glucose
NORMALVARIATION
height
leptin
lipids
cortisol
body mass
bone density
Normal variation in leptin levels
METABOLIC
obesity
insulin
DEVELOPMENTAL
No data
Desease Name
Obesity, early-onset, susceptibility to
Obesity, adrenal insufficiency, and red hair due to POMC deficiency
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of POMC mRNAaffects expression 21346803
C031278 2-chloroethyl ethyl sulfide 2-chloroethyl ethyl sulfide results in decreased expression of POMC mRNAdecreases expression 16289378
C054649 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol affects the expression of POMC mRNAaffects expression 12641731
C002385 3-morpholino-sydnonimine 3-morpholino-sydnonimine results in increased secretion of POMC protein alternative formincreases secretion 10460269
C002385 3-morpholino-sydnonimine CRH protein affects the reaction [3-morpholino-sydnonimine results in increased secretion of POMC protein alternative form]affects reaction|increases secretion 10460269
D000079 Acetaldehyde Acetaldehyde results in increased expression of POMC mRNAincreases expression 7704432
D000079 Acetaldehyde Acetaldehyde results in increased expression of POMC proteinincreases expression 7704432
D000082 Acetaminophen Acetaminophen results in decreased expression of POMC proteindecreases expression 16449370
D000082 Acetaminophen Acetaminophen inhibits the reaction [POMC protein results in increased abundance of Hydrocortisone]decreases reaction|increases abundance 16551645
D000109 Acetylcholine Acetylcholine results in increased expression of POMC mRNAincreases expression 7588217
D000109 Acetylcholine Acetylcholine results in increased expression of POMC proteinincreases expression 7588217
D000109 Acetylcholine Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein]decreases reaction|increases expression 7588217
D000109 Acetylcholine Pentobarbital inhibits the reaction [Acetylcholine results in increased expression of POMC protein]decreases reaction|increases expression 7588217
D020106 Acrylamide Acrylamide results in increased expression of POMC mRNAincreases expression 15003292
D020106 Acrylamide Acrylamide results in increased expression of POMC proteinincreases expression 15003292
C011512 alpha-naphthoflavone alpha-naphthoflavone results in decreased activity of POMC proteindecreases activity 15635147
C011512 alpha-naphthoflavone [beta-Naphthoflavone co-treated with alpha-naphthoflavone] results in decreased activity of POMC proteinaffects cotreatment|decreases activity 15635147
C011512 alpha-naphthoflavone [beta-Naphthoflavone co-treated with alpha-naphthoflavone] results in increased expression of POMC proteinaffects cotreatment|increases expression 15635147
D006710 Homocysteine Homocysteine results in increased expression of POMC mRNAincreases expression 17326132
D000643 Ammonium Chloride Ammonium Chloride affects the expression of POMC mRNAaffects expression 16483693
C103016 antalarmin antalarmin affects the reaction [CRH protein results in increased expression of POMC protein alternative form]affects reaction|increases expression 14997174
D001218 Aspartame Aspartame results in increased expression of POMC protein alternative formincreases expression 1805284
C528574 astressin-2B astressin-2B results in increased secretion of POMC protein alternative formincreases secretion 12746300
C120841 astressin B astressin B inhibits the reaction [CRH protein results in increased expression of POMC protein alternative form]decreases reaction|increases expression 14997174
C120841 astressin B astressin B inhibits the reaction [CARTPT protein results in increased secretion of POMC protein alternative form]decreases reaction|increases secretion 15271883
C120841 astressin B astressin B inhibits the reaction [CRH protein results in increased secretion of POMC protein alternative form]decreases reaction|increases secretion 10447963
C120841 astressin B astressin B inhibits the reaction [Ethanol results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
C120841 astressin B astressin B inhibits the reaction [Lipopolysaccharides results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
C120841 astressin B astressin B inhibits the reaction [Lipopolysaccharides results in increased expression of POMC protein alternative form]decreases reaction|increases expression 12207160
C120841 astressin B astressin B inhibits the reaction [Turpentine results in increased expression of POMC protein alternative form]decreases reaction|increases expression 12207160
D001285 Atropine Atropine inhibits the reaction [Acetylcholine results in increased expression of POMC protein]decreases reaction|increases expression 7588217
D019324 beta-Naphthoflavone [beta-Naphthoflavone co-treated with alpha-naphthoflavone] results in decreased activity of POMC proteinaffects cotreatment|decreases activity 15635147
D019324 beta-Naphthoflavone [beta-Naphthoflavone co-treated with alpha-naphthoflavone] results in increased expression of POMC proteinaffects cotreatment|increases expression 15635147
D019324 beta-Naphthoflavone beta-Naphthoflavone results in decreased activity of POMC proteindecreases activity 15635147
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of ICAM1 mRNA]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP2 mRNA]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF mRNA]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein inhibits the reaction [Carbon Tetrachloride results in increased expression of VCAM1 mRNA]decreases reaction|increases expression 16508911
D002251 Carbon Tetrachloride POMC protein promotes the reaction [Carbon Tetrachloride results in increased activity of MMP2 protein]increases activity|increases reaction 16508911
D002251 Carbon Tetrachloride POMC protein promotes the reaction [Carbon Tetrachloride results in increased expression of MMP1 protein]increases expression|increases reaction 16508911
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in increased expression of POMC mRNAincreases expression 15721885
D003000 Clonidine Clonidine results in increased secretion of POMC protein alternative formincreases secretion 10898105
D003000 Clonidine Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form]decreases reaction|increases secretion 10898105
D003484 Cyanamide [Ethanol co-treated with Cyanamide] results in increased expression of POMC mRNAaffects cotreatment|increases expression 11139417
D003520 Cyclophosphamide Cyclophosphamide results in increased expression of POMC proteinincreases expression 15276878
D003634 DDT [Lindane co-treated with DDT] results in increased expression of POMCaffects cotreatment|increases expression 16329587
D004221 Disulfiram Disulfiram results in decreased expression of POMC protein alternative formdecreases expression 8246921
D000431 Ethanol Ethanol results in decreased expression of POMC mRNAdecreases expression 17934066
D000431 Ethanol fomepizole inhibits the reaction [Ethanol results in decreased expression of POMC mRNA]decreases expression|decreases reaction 17934066
D000431 Ethanol astressin B inhibits the reaction [Ethanol results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
D000431 Ethanol [Ethanol co-treated with Cyanamide] results in increased expression of POMC mRNAaffects cotreatment|increases expression 11139417
D000431 Ethanol Ethanol results in decreased secretion of POMC protein alternative formdecreases secretion 12746300
D000431 Ethanol Ethanol results in increased expression of POMC mRNAincreases expression 7704432
16925589
D000431 Ethanol Ethanol results in increased expression of POMC proteinincreases expression 16925589
7704432
D000431 Ethanol R 121919 inhibits the reaction [Ethanol results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of POMC mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POMC mRNAaffects cotreatment|increases expression 17942748
C010238 fomepizole fomepizole inhibits the reaction [Ethanol results in decreased expression of POMC mRNA]decreases expression|decreases reaction 17934066
D005557 Formaldehyde Formaldehyde results in increased expression of POMC mRNAincreases expression 15805735
D005557 Formaldehyde Formaldehyde results in increased expression of POMC proteinincreases expression 15805735
D005632 Fructose Fructose results in decreased expression of POMC mRNAdecreases expression 18627777
D005947 Glucose Glucose results in decreased expression of POMC mRNAdecreases expression 18627777
D006854 Hydrocortisone Acetaminophen inhibits the reaction [POMC protein results in increased abundance of Hydrocortisone]decreases reaction|increases abundance 16551645
D006854 Hydrocortisone Ibuprofen inhibits the reaction [POMC protein results in increased abundance of Hydrocortisone]decreases reaction|increases abundance 16551645
D006854 Hydrocortisone POMC protein results in increased abundance of Hydrocortisoneincreases abundance 16551645
D006854 Hydrocortisone Salicylic Acid inhibits the reaction [POMC protein results in increased abundance of Hydrocortisone]decreases reaction|increases abundance 16551645
D007052 Ibuprofen Ibuprofen inhibits the reaction [POMC protein results in increased abundance of Hydrocortisone]decreases reaction|increases abundance 16551645
D007213 Indomethacin Indomethacin inhibits the reaction [Clonidine results in increased secretion of POMC protein alternative form]decreases reaction|increases secretion 10898105
D007213 Indomethacin Indomethacin inhibits the reaction [Phenylephrine results in increased secretion of POMC protein alternative form]decreases reaction|increases secretion 10898105
D007545 Isoproterenol Isoproterenol results in increased secretion of POMC protein alternative formincreases secretion 10898105
D001556 Lindane [Lindane co-treated with DDT] results in increased expression of POMCaffects cotreatment|increases expression 16329587
D008070 Lipopolysaccharides Lipopolysaccharides affects the expression of POMC mRNAaffects expression 15667454
D008070 Lipopolysaccharides astressin B inhibits the reaction [Lipopolysaccharides results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
D008070 Lipopolysaccharides astressin B inhibits the reaction [Lipopolysaccharides results in increased expression of POMC protein alternative form]decreases reaction|increases expression 12207160
D008070 Lipopolysaccharides Lipopolysaccharides results in decreased secretion of POMC protein alternative formdecreases secretion 12746300
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of POMC protein alternative formincreases expression 12207160
D008070 Lipopolysaccharides R 121919 inhibits the reaction [Lipopolysaccharides results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
C014655 methamidophos methamidophos results in increased expression of POMC protein alternative formincreases expression 11048668
D008797 Metyrapone Metyrapone results in increased expression of POMC proteinincreases expression 15265784
D009020 Morphine Morphine results in increased expression of POMC mRNAincreases expression 20144693
D009020 Morphine [Zymosan co-treated with Morphine] results in increased expression of POMC mRNAaffects cotreatment|increases expression 15979727
D009118 Muscimol Muscimol promotes the reaction [Pentobarbital results in decreased expression of POMC mRNA]decreases expression|increases reaction 7937335
D009118 Muscimol Muscimol results in decreased expression of POMC mRNAdecreases expression 7937335
D009151 Mustard Gas Mustard Gas results in increased expression of POMC protein alternative formincreases expression 8299707
D009569 Nitric Oxide CRH protein affects the reaction [Nitric Oxide results in increased secretion of POMC protein alternative form]affects reaction|increases secretion 10460269
D009569 Nitric Oxide Nitric Oxide results in increased secretion of POMC protein alternative formincreases secretion 10460269
D020030 Nitric Oxide Donors CRH protein affects the reaction [Nitric Oxide Donors results in increased secretion of POMC protein alternative form]affects reaction|increases secretion 10460269
D020030 Nitric Oxide Donors Nitric Oxide Donors results in increased secretion of POMC protein alternative formincreases secretion 10460269
D010424 Pentobarbital Muscimol promotes the reaction [Pentobarbital results in decreased expression of POMC mRNA]decreases expression|increases reaction 7937335
D010424 Pentobarbital Pentobarbital inhibits the reaction [Acetylcholine results in increased expression of POMC protein]decreases reaction|increases expression 7588217
D010424 Pentobarbital Pentobarbital results in decreased expression of POMC mRNAdecreases expression 7937335
D010656 Phenylephrine Indomethacin inhibits the reaction [Phenylephrine results in increased secretion of POMC protein alternative form]decreases reaction|increases secretion 10898105
D010656 Phenylephrine Phenylephrine results in increased secretion of POMC protein alternative formincreases secretion 10898105
D010665 Phenylpropanolamine Phenylpropanolamine results in increased expression of POMC mRNAincreases expression 17684035
D010665 Phenylpropanolamine Phenylpropanolamine results in increased expression of POMC proteinincreases expression 17684035
C412383 R 121919 R 121919 inhibits the reaction [Ethanol results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
C412383 R 121919 R 121919 inhibits the reaction [Lipopolysaccharides results in decreased secretion of POMC protein alternative form]decreases reaction|decreases secretion 12746300
C025759 saikosaponin saikosaponin results in increased expression of POMC mRNAincreases expression 8552307
C025759 saikosaponin saikosaponin results in increased expression of POMC proteinincreases expression 8552307
C080903 sairei-to CRH protein affects the reaction [sairei-to results in increased expression of POMC protein]affects reaction|increases expression 8247339
C080903 sairei-to [sairei-to results in increased expression of CRH protein] which results in increased expression of POMC mRNAincreases expression 8233027
C080903 sairei-to [sairei-to results in increased expression of CRH protein] which results in increased expression of POMC proteinincreases expression 8233027
C080903 sairei-to sairei-to results in increased expression of POMC mRNAincreases expression 8247339
C080903 sairei-to sairei-to results in increased expression of POMC proteinincreases expression 8247339
D020156 Salicylic Acid Salicylic Acid inhibits the reaction [POMC protein results in increased abundance of Hydrocortisone]decreases reaction|increases abundance 16551645
D013311 Streptozocin INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA]decreases expression|decreases reaction 20219977
D013311 Streptozocin Streptozocin results in decreased expression of POMC mRNAdecreases expression 20219977
D013549 Sweetening Agents Sweetening Agents results in decreased expression of POMC mRNAdecreases expression 18627777
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of POMC mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of POMC mRNAincreases expression 12520768
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of POMC proteinincreases expression 12520768
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with LEP protein] affects the expression of POMC mRNAaffects cotreatment|affects expression 15977195
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of POMC mRNAincreases expression 15093705
18824019
D013752 Tetracycline Tetracycline results in increased expression of POMC mRNAincreases expression 16917069
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased degradation of NFKBIA protein]decreases reaction|increases degradation 15313186
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of and results in increased activity of TIMP1 protein]decreases reaction|increases activity|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of ICAM1 mRNA]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of NOS2 mRNA]decreases reaction|increases expression 15313186
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of PCNA protein]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of PTGS2 protein]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of TGFB1 mRNA]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of TNF mRNA]decreases reaction|increases expression 16511523
15313186
D013853 Thioacetamide POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of VCAM1 mRNA]decreases reaction|increases expression 16511523
D013853 Thioacetamide POMC protein alternative form promotes the reaction [Thioacetamide results in increased activity of MMP2 protein]increases activity|increases reaction 16511523
D013853 Thioacetamide POMC protein alternative form promotes the reaction [Thioacetamide results in increased expression of MMP1 mRNA]increases expression|increases reaction 16511523
D013853 Thioacetamide POMC protein alternative form promotes the reaction [Thioacetamide results in increased expression of MMP8 mRNA]increases expression|increases reaction 16511523
D013875 Thiophanate Thiophanate results in decreased expression of POMC proteindecreases expression 17549544
D014050 Toluene Toluene results in increased expression of POMC proteinincreases expression 15707876
D014425 Turpentine astressin B inhibits the reaction [Turpentine results in increased expression of POMC protein alternative form]decreases reaction|increases expression 12207160
D014425 Turpentine Turpentine results in increased expression of POMC protein alternative formincreases expression 12207160
D014801 Vitamin A Vitamin A results in increased expression of POMC proteinincreases expression 17373634
D015054 Zymosan [Zymosan co-treated with Morphine] results in increased expression of POMC mRNAaffects cotreatment|increases expression 15979727
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Disulfiram 10.9017676605
MESH:D000014 Abnormalities, Drug-Induced Ethanol 10.9018926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.9014514962 15322242 11752688
MESH:D000015 Abnormalities, Multiple Vitamin A 4.3110992263
MESH:D000138 Acidosis Ammonium Chloride 8.4218287403
MESH:D000138 Acidosis Ethanol 8.4211192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.3117505938
MESH:D000163 Acquired Immunodeficiency Syndrome Disulfiram 4.959207937
MESH:D058186 Acute Kidney Injury Ibuprofen 3.906375363
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.4711850527 18653653
MESH:D000210 Acute-Phase Reaction Turpentine 5.5616044259
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.0814692618
MESH:D000230 Adenocarcinoma Ibuprofen 6.0810697514
MESH:D000230 Adenocarcinoma Indomethacin 6.0816537180
MESH:D000236 Adenoma beta-Naphthoflavone 5.8119389873
MESH:D000236 Adenoma Indomethacin 5.8111497255
MESH:D018248 Adenoma, Liver Cell DDT 8.5012597452
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.5016835633
MESH:D000382 Agricultural Workers' Diseases DDT 7.2912584743 16487989
MESH:D000382 Agricultural Workers' Diseases Lindane 7.2912661182
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.6915451040 15451039
MESH:D000437 Alcoholism Disulfiram 4.4917079463 18968458 10841824
MESH:D000505 Alopecia astressin B 5.3921359208
MESH:D016301 Alveolar Bone Loss Indomethacin 4.7417225004
MESH:D000544 Alzheimer Disease Ibuprofen 5.8418351690
MESH:D000544 Alzheimer Disease Indomethacin 5.8415579461 17627676
MESH:D000544 Alzheimer Disease Nitric Oxide 5.8417556102
MESH:D000707 Anaphylaxis Ibuprofen 4.649532969
MESH:D000740 Anemia Tetrachlorodibenzodioxin 11.9111748828
MESH:D000740 Anemia Vitamin A 11.9116960172
MESH:D000740 Anemia Zymosan 11.9118664788
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.2616960172
MESH:D000755 Anemia, Sickle Cell Aspartame 5.4711372003
MESH:D000799 Angioedema Acetaminophen 3.2110982225
MESH:D000853 Anophthalmos Ethanol 4.2215513904
MESH:D000855 Anorexia Phenylpropanolamine 5.1917684035
MESH:D001008 Anxiety Disorders Ethanol 7.7611141031
MESH:D001008 Anxiety Disorders Pentobarbital 7.7618313124 11141031
MESH:D001014 Aortic Aneurysm Indomethacin 4.2610231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.2710388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.5817460149
MESH:D001161 Arteriosclerosis Cyclophosphamide 8.1715014928
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.1711256880
MESH:D018771 Arthralgia Indomethacin 4.542160914
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.2315885639
MESH:D001169 Arthritis, Experimental Zymosan 6.2316872482 17659584 15188379 15944321 15142272
MESH:D001172 Arthritis, Rheumatoid Aspartame 4.7810777254
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.7811248219
MESH:D001249 Asthma Acetaldehyde 6.859600491
MESH:D001249 Asthma Mustard Gas 6.8510378619
MESH:D001249 Asthma Vitamin A 6.8516732791
MESH:D001321 Autistic Disorder marker/mechanism 8570775
MESH:D001321 Autistic Disorder Acetaminophen 2.2518445737
MESH:D001321 Autistic Disorder Homocysteine 2.2516297937 20468076
MESH:D001342 Autonomic Nervous System Diseases methamidophos 6.1511527224
MESH:D001477 Bartter Syndrome Indomethacin 4.3810684365
MESH:D001768 Blister Mustard Gas 4.5419167455
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 7.3012125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 7.3019483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.1615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.3415746008
MESH:D001919 Bradycardia antalarmin 14.4416710322
MESH:D001919 Bradycardia Isoproterenol 14.446740701
MESH:D001919 Bradycardia Phenylephrine 14.4415306635
MESH:D001929 Brain Edema Indomethacin 4.4011481608
MESH:D002545 Brain Ischemia Ibuprofen 13.7415837124
MESH:D002545 Brain Ischemia Indomethacin 13.7412524144
MESH:D002545 Brain Ischemia Morphine 13.7419211983
MESH:D001943 Breast Neoplasms Acrylamide 6.0218183576 16253758
MESH:D001943 Breast Neoplasms Atropine 6.0212762645
MESH:D001943 Breast Neoplasms Cyclophosphamide 6.0217388661 17020986 11325840 16978400 18323546 12006526 18234424 15093573 15136595
MESH:D001943 Breast Neoplasms DDT 6.0212709520 16792888
MESH:D001943 Breast Neoplasms Disulfiram 6.0217026967
MESH:D001943 Breast Neoplasms Formaldehyde 6.0215986119
MESH:D001943 Breast Neoplasms Indomethacin 6.0217401462
MESH:D001943 Breast Neoplasms Lindane 6.0214688026
MESH:D001943 Breast Neoplasms Nitric Oxide 6.0215631943
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.0220435547
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.5415286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.3517687719 10378619
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 4.9817426644 17377406
MESH:D002056 Burns Ethanol 9.3816374292
MESH:D002056 Burns Indomethacin 9.3810459503
MESH:D002100 Cachexia Ibuprofen 10.6215141370
MESH:D002100 Cachexia Indomethacin 10.6215141370 16537180 11239499 15625704
MESH:D002177 Candidiasis Disulfiram 5.2415325261
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.1816011737 16227642 16050911 15721981 16124888 18705752 10355542 15700767 16192424 15673190 16097048 3786805
MESH:D002276 Carcinoid Tumor Streptozocin 4.9716051944
MESH:D002277 Carcinoma Disulfiram 6.9817026967
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.9816835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 14.4516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 14.453084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 14.4518788625
MESH:D006528 Carcinoma, Hepatocellular Cyclophosphamide 14.4519701751
MESH:D006528 Carcinoma, Hepatocellular DDT 14.4512597452
MESH:D006528 Carcinoma, Hepatocellular Ethanol 14.4518788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 14.4516391822
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 14.4517997003
MESH:D018827 Carcinoma, Lewis Lung Cyclophosphamide 9.4916152834
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 9.4911053908
MESH:D018276 Carcinoma, Medullary Indomethacin 4.7318791128 14736730 11352223
MESH:D002289 Carcinoma, Non-Small-Cell Lung Disulfiram 3.6717026967
MESH:D002292 Carcinoma, Renal Cell Cyclophosphamide 5.8516201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 5.8517341418
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 2.6512636206 15482327
MESH:D006332 Cardiomegaly Ethanol 13.3019332462
MESH:D006332 Cardiomegaly Isoproterenol 13.307544033 11179087
MESH:D006332 Cardiomegaly Phenylephrine 13.3015728586 11754973 17124262 16170337 17287366 11179087
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 13.3018850075 18670907 16120746
MESH:D002310 Cardiomyopathy, Alcoholic Acetaldehyde 5.8510525098
MESH:D002386 Cataract Acetaminophen 6.4310977129
MESH:D002386 Cataract Disulfiram 6.4317936468 15003327
MESH:D002418 Cattle Diseases Acrylamide 4.8212510666
MESH:D002547 Cerebral Palsy Toluene 5.239294310
MESH:D015362 Child Nutrition Disorders Vitamin A 4.8516153327
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 7.8016835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 7.8018291259
MESH:D002764 Cholecystitis Indomethacin 4.5411181007
MESH:D002779 Cholestasis Ethinyl Estradiol 11.0217681005 17110522 15861022 11677210 16105132 17333356 16919318
MESH:D002779 Cholestasis Nitric Oxide 11.0216919318
MESH:D002779 Cholestasis Vitamin A 11.0216175620
MESH:D016770 Ciliophora Infections Formaldehyde 5.0212113305
MESH:D002971 Cleft Lip Ethanol 3.2315513904
MESH:D002972 Cleft Palate Ethanol 11.7215513904
MESH:D002972 Cleft Palate Hydrocortisone 11.7215826874
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 11.7212621046 8697196 16354765 15340226 15668235
MESH:D002972 Cleft Palate Vitamin A 11.7216054864
MESH:D019970 Cocaine-Related Disorders Disulfiram 5.1319462300
MESH:D003110 Colonic Neoplasms Indomethacin 3.7611260862 15625704 15963497 15936596 15637740 15786552
MESH:D003110 Colonic Neoplasms Vitamin A 3.7616267017 17219422
MESH:D015179 Colorectal Neoplasms Indomethacin 2.3518059344 12606626 17054584 11197048
MESH:D000013 Congenital Abnormalities DDT 7.7115095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 7.7114669216 17141729
MESH:D003324 Coronary Artery Disease Homocysteine 3.5016379339
MESH:D003327 Coronary Disease Fructose 4.0518504504
MESH:D018352 Coronavirus Infections Indomethacin 5.0917302372
MESH:D019465 Craniofacial Abnormalities Ethanol 6.3415451039 10194807 15513904 11198716 15451040 19302082 11873399
MESH:D019465 Craniofacial Abnormalities Hydrocortisone 6.3417728286
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.3420055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Toluene 6.349294310
MESH:D019465 Craniofacial Abnormalities Vitamin A 6.3410992263
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.4118551238
MESH:D003556 Cystitis Cyclophosphamide 4.3612388444 18483878 18710439 18295254 18433785 17979934 12913760 10700343 12161096 11948286 16651033 16989017 18093676 16413132 16614059 15276878 18372110 17010015 15643279 10498854
MESH:D003643 Death Toluene 5.046431079
MESH:D015140 Dementia, Vascular Nitric Oxide 5.3417556102
MESH:D003731 Dental Caries Aspartame 6.298955999
MESH:D017449 Dermatitis, Allergic Contact Aspartame 6.2914996049
MESH:D017449 Dermatitis, Allergic Contact Formaldehyde 6.2916958921 15059100 15932584 12081698 14996049
MESH:D003920 Diabetes Mellitus Streptozocin 4.2016285004
MESH:D003921 Diabetes Mellitus, Experimental Cyclophosphamide 11.3111751995 10990075 15331540
MESH:D003921 Diabetes Mellitus, Experimental Fructose 11.3118603373
MESH:D003921 Diabetes Mellitus, Experimental Streptozocin 11.3117442507 2177838 16286809 15862027 15831366 19960420 8740154 19298542 1374869 16684804 11260395 12644472 17874149 18603373 15298345 6379147 19586609 12446591 11055810 19496084 12093613 7637645 18715473 12083368
MESH:D003922 Diabetes Mellitus, Type 1 Cyclophosphamide 7.8318772604
MESH:D003922 Diabetes Mellitus, Type 1 Streptozocin 7.8318603373
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 7.8316506275
MESH:D003924 Diabetes Mellitus, Type 2 Fructose 6.2218603373
MESH:D003924 Diabetes Mellitus, Type 2 Streptozocin 6.2219647726 19586609
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.2217107852
MESH:D058065 Diabetic Cardiomyopathies Streptozocin 5.1116025228
MESH:D003928 Diabetic Nephropathies Streptozocin 4.1519960420 19682444
MESH:D003930 Diabetic Retinopathy Streptozocin 4.8417662242
MESH:D003967 Diarrhea 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 18.7210611417
MESH:D003967 Diarrhea Atropine 18.7210867622
MESH:D003967 Diarrhea Hydrocortisone 18.727237001
MESH:D003967 Diarrhea Indomethacin 18.727237001 7907874
MESH:D003967 Diarrhea Morphine 18.722540324
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 18.1221346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 18.1216177239 10774834 16109766 14550746 17906064 11287661 11461765 12153990 16227642 18713872 14986274 11529661 15968718 16485898 19085960 2444490 11421492 12540782 17522070 19923254 12594235 19370779 15619225 12392966 11834606 10915739 19420014 10663392 19739265 11739529 12958197 17562736 16081117 12705907 14725611 16393943 19416960 18071297 19164858 11743745 16781746
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 18.126884620 2869522 19336974 17522070 7120509 10915739 7440962 15027814 15998439 4309450 11566570 7179309 19085960 21278145 16227642 9327722 16177239 15968718 3786805 10092053 6623471 3732212
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 18.1217851650
MESH:D056486 Drug-Induced Liver Injury Ethanol 18.1211566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 18.1220420201
MESH:D056486 Drug-Induced Liver Injury Tetracycline 18.1217522070
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 18.1212963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.4719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.2911462148
MESH:D015352 Dry Eye Syndromes Vitamin A 5.1816146918
MESH:D004374 Ductus Arteriosus, Patent Ibuprofen 11.1816133044 18446180 18450898
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 11.1816133044 18446180 12774134 18043480 17190690 16326151
MESH:D004381 Duodenal Ulcer Atropine 7.9411595415
MESH:D004381 Duodenal Ulcer Indomethacin 7.9417329845 17045617 11535926 11991626 17151854 11595431 17351913 11595415 17202747 16699067 10671773
MESH:D004417 Dyspnea DDT 4.5416487989
MESH:C538011 Eales disease Vitamin A 4.999068938
MESH:D004480 Ectromelia Vitamin A 5.1916054864
MESH:D004487 Edema Indomethacin 12.048985016 19703484 10653021 16100529 8273558 7907874 7990266
MESH:D004487 Edema Mustard Gas 12.0411428631 9260866 11402378 11428647
MESH:D004487 Edema Tetrachlorodibenzodioxin 12.0412711302 11000095
MESH:D004487 Edema Zymosan 12.047907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.2716714409 18230668 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.6112538720
MESH:D004715 Endometriosis Ibuprofen 12.3015652904
MESH:D004715 Endometriosis Indomethacin 12.3015652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 12.3010568697 9294722
MESH:D019446 Endotoxemia Ibuprofen 14.1411545620
MESH:D019446 Endotoxemia Indomethacin 14.1418509659
MESH:D019446 Endotoxemia Lipopolysaccharides 14.1415328337 15821434 17637181
MESH:D004751 Enteritis Clonidine 9.968982514
MESH:D004751 Enteritis Indomethacin 9.9616328016 10567023 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 4.3817980183
MESH:D004802 Eosinophilia Cyclophosphamide 7.2511006010
MESH:D004802 Eosinophilia Indomethacin 7.2511298111
MESH:D004890 Erythema Mustard Gas 4.549357497
MESH:D004893 Erythema Nodosum Aspartame 6.299324739
MESH:D004938 Esophageal Neoplasms Ethanol 4.2216704527
MESH:D004938 Esophageal Neoplasms Indomethacin 4.2211005569
MESH:D017889 Exfoliation Syndrome Homocysteine 5.0816504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.5411564622
MESH:D005141 Eyelid Diseases Aspartame 11.9214996049
MESH:D005141 Eyelid Diseases Formaldehyde 11.9214996049
MESH:D005218 Fat Necrosis Thioacetamide 5.0916456712
MESH:D005234 Fatty Liver Carbon Tetrachloride 18.8612631006 16045604 12795759 61145 19224547 17595544 15959796 16239168
MESH:D005234 Fatty Liver Ethanol 18.8616409862 18620774 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.8615345470
MESH:D005234 Fatty Liver Fructose 18.8618395287 19196556 18641190
MESH:D005234 Fatty Liver Tetracycline 18.8616917069 19224547
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.0317920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.6810194807 16946407 15513904 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 2.8611858732
MESH:D005327 Fetal Resorption Vitamin A 4.7416054864
MESH:D005334 Fever Aspartame 17.359630831
MESH:D005334 Fever Ibuprofen 17.3516997862
MESH:D005334 Fever Indomethacin 17.3517627676 11852909 10431976
MESH:D005334 Fever Lipopolysaccharides 17.3511852909 9205823
MESH:D005354 Fibrosarcoma Indomethacin 4.2810962813
MESH:D005355 Fibrosis Carbon Tetrachloride 16.3218705752
MESH:D005355 Fibrosis Fructose 16.3218504504
MESH:D005355 Fibrosis Indomethacin 16.3217994277
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 16.3220067830
MESH:D005393 Fish Diseases Formaldehyde 4.9812113305
MESH:D005499 Folliculitis Indomethacin 4.5411298111
MESH:D005517 Foodborne Diseases methamidophos 6.5111527224
MESH:D005756 Gastritis Acetaminophen 15.4216983495
MESH:D005756 Gastritis Ethanol 15.4215046732
MESH:D005756 Gastritis Indomethacin 15.4215046732
MESH:D005901 Glaucoma Homocysteine 4.7216504073
MESH:D005909 Glioblastoma Indomethacin 3.1512870263
MESH:D005910 Glioma Indomethacin 2.9516487511 18371953
MESH:D018316 Gliosarcoma Cyclophosphamide 4.9011389073
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.7811849393
MESH:D018149 Glucose Intolerance Fructose 4.7519165636
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 3.9610696789
MESH:D006073 Gout Indomethacin 4.7311248219
MESH:D006086 Graft vs Host Disease Cyclophosphamide 4.4311014644 16376943 15172196
MESH:D006261 Headache Nitric Oxide 4.5511554966 11284996
MESH:D006258 Head and Neck Neoplasms Indomethacin 3.3115482327
MESH:D006330 Heart Defects, Congenital Homocysteine 9.3119638421
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.3110048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin A 9.3110992263 16080930
MESH:D006331 Heart Diseases Streptozocin 3.8312093613
MESH:D006333 Heart Failure Isoproterenol 3.8418097624
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.8416366002
MESH:D006467 Hemophilia A Cyclophosphamide 4.6911918545
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.7811000095
MESH:D006501 Hepatic Encephalopathy Indomethacin 9.0915633222
MESH:D006501 Hepatic Encephalopathy Thioacetamide 9.0918665440 17276928 15929193
MESH:D006504 Hepatic Veno-Occlusive Disease Cyclophosphamide 4.9014986274
MESH:D006505 Hepatitis Carbon Tetrachloride 17.7219110552 19900420
MESH:D006505 Hepatitis DDT 17.7216487989
MESH:D006505 Hepatitis Thioacetamide 17.7216456712
MESH:D006505 Hepatitis Zymosan 17.7219110552
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.0915135802
MESH:D006529 Hepatomegaly DDT 6.922387028
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.9215340226 16120746 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin A 3.3717436238 16863852 16292552 16877224 15707848 16490937
MESH:D015658 HIV Infections Vitamin A 3.4716960176
MESH:D006679 HIV Seropositivity Vitamin A 4.9817209195
MESH:D006689 Hodgkin Disease Cyclophosphamide 3.2817606976 16135485
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.4216959395 8697196 18606429 16354765 15340226
MESH:D006930 Hyperalgesia Acetaminophen 10.2816870215
MESH:D006930 Hyperalgesia Ethanol 10.2818783367
MESH:D006930 Hyperalgesia Indomethacin 10.2812727271
MESH:D034321 Hyperamylasemia Indomethacin 5.0917883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9116899240
MESH:D006940 Hyperemia Indomethacin 10.6712524144
MESH:D006940 Hyperemia Nitric Oxide 10.6711156591
MESH:D020138 Hyperhomocysteinemia Homocysteine 4.1817292331 18234410 17369066
MESH:D006946 Hyperinsulinism Fructose 4.3814757778 18360027 19008412 15752949 18563319
MESH:D006949 Hyperlipidemias Fructose 7.8715752949
MESH:D006949 Hyperlipidemias Indomethacin 7.8717546600
MESH:D006973 Hypertension Aspartame 10.2218708962
MESH:D006973 Hypertension Fructose 10.2216843071 14573337 14633139 19008412 14568997
MESH:D006973 Hypertension Phenylephrine 10.228949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.2218850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.4915338365
MESH:D046110 Hypertension, Pregnancy-Induced Clonidine 5.5616612254
MESH:D006976 Hypertension, Pulmonary Nitric Oxide 3.9615838368
MESH:D015228 Hypertriglyceridemia Fructose 4.5419342510 19799862
MESH:D006984 Hypertrophy Ibuprofen 14.7016672835
MESH:D006984 Hypertrophy Isoproterenol 14.7012791704
MESH:D006984 Hypertrophy Phenylephrine 14.7018502941 12791704
MESH:D006986 Hypervitaminosis A Vitamin A 5.5416054864
MESH:D007021 Hypospadias Ethinyl Estradiol 3.2116569931 16945680
MESH:D007022 Hypotension Isoproterenol 4.236740701
MESH:D007077 Ileal Diseases Indomethacin 4.4018306037 10574470
MESH:D007079 Ileitis Indomethacin 4.7316133968 10651667 10647630
MESH:D007154 Immune System Diseases Cyclophosphamide 4.7016076520
MESH:D007235 Infant, Premature, Diseases Ibuprofen 12.1016133044
MESH:D007235 Infant, Premature, Diseases Indomethacin 12.1016133044
MESH:D007247 Infertility, Female Acrylamide 8.4911020651
MESH:D007247 Infertility, Female Ethinyl Estradiol 8.4912013081
MESH:D007248 Infertility, Male Acrylamide 16.6012507653 15749267 15355880 11020651
MESH:D007248 Infertility, Male Cyclophosphamide 16.607193160 16517039
MESH:D007248 Infertility, Male DDT 16.6017192596 17157474
MESH:D007248 Infertility, Male Ethinyl Estradiol 16.6017937319
MESH:D007248 Infertility, Male methamidophos 16.6010828210
MESH:D007249 Inflammation Ibuprofen 15.343291741
MESH:D007249 Inflammation Indomethacin 15.3412568917 7812673 3291741
MESH:D007249 Inflammation Lipopolysaccharides 15.3412878042 17963957 17255318 17237260 9205823
MESH:D007249 Inflammation Mustard Gas 15.3417524151 11428631 11428620 9260866 8975870 11402378 9357497 16001271 11428647
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 15.3412200463 12878042
MESH:D007249 Inflammation Zymosan 15.3411289658 8014878
MESH:D007333 Insulin Resistance Fructose 3.8218057795 18981581 19008412 19799862 14633139 14757778 18563319 19342510 14573337 17133782 19586609
MESH:D007410 Intestinal Diseases Indomethacin 8.3218236018 11686837 15610444 17329856 17994277 15831440 10210152 11713966 11855677
MESH:D007410 Intestinal Diseases Nitric Oxide 8.3210210152 11574821 11713966
MESH:D019586 Intracranial Hypertension Indomethacin 12.1015241188
MESH:D019586 Intracranial Hypertension Vitamin A 12.1015955940
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.0617255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.2217553498
MESH:D007569 Jaw Abnormalities Ethanol 8.2715513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.2716580747
MESH:D007579 Jejunal Diseases Indomethacin 4.4010574470 18306037 16133968
MESH:D007674 Kidney Diseases Acetaminophen 11.4215629191 12587719
MESH:D007674 Kidney Diseases Aspartame 11.4211409539
MESH:D007674 Kidney Diseases Indomethacin 11.4217190690
MESH:D007674 Kidney Diseases Streptozocin 11.4212093613
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 2.4816705839
MESH:D007859 Learning Disorders DDT 8.137589230
MESH:D007859 Learning Disorders Ethanol 8.1315451040
MESH:D007896 Leishmaniasis Nitric Oxide 4.1317218153
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.4010320625 11703811 12228301
MESH:D007938 Leukemia Cyclophosphamide 3.1610602166
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Cyclophosphamide 6.1117296974 17658394 17008537 17802794 18587576 18172266
MESH:D015451 Leukemia, Lymphocytic, Chronic, B-Cell Disulfiram 6.1117026967
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Cyclophosphamide 7.2310373061
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 7.2315631656 16572323 10785260
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.5118360721
MESH:D007964 Leukocytosis Indomethacin 4.7416537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.0917980183
MESH:D007970 Leukopenia Cyclophosphamide 9.7210052129 11830472
MESH:D007970 Leukopenia Lipopolysaccharides 9.7215821434
MESH:D017880 Limb Deformities, Congenital Disulfiram 11.3617676605
MESH:D017880 Limb Deformities, Congenital Ethanol 11.3617676605
MESH:D017880 Limb Deformities, Congenital Vitamin A 11.3616054864
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.0911479899
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 9.0516221502 11903743 16239168 16943688 17174718 21278145 11408273 17157831 17334410
MESH:D008103 Liver Cirrhosis Ethanol 9.0515289165
MESH:D008103 Liver Cirrhosis Vitamin A 9.0516256175
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.4818295389
MESH:D008106 Liver Cirrhosis, Experimental therapeutic 16511523 16508911
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.2317708605 14716833 17557913 15650968 15673190 18481824 18279442 15876570 17714472 18166357 18395914 18395095 17761835 16638106 18251166 20821823 17721639 14748882 18006644 16097048 18412020 11481614 12632514 18472332 12389079 18418968 12898905 12586293 17698563 17525996 18339082 17922224 15818738 12667390 15730626 17869086 16248980 14724832 17823541 18472094 15925388 15893842 18205269 17976157 14620537 15959796 15362042 18156304 10355542 12958196 12666154 16136751 18054572 17631135 16015684 12632512 15123356 16192424 15338365 15996030 18210741 18277467 17805973 15052691 12445418 18420326 15370692 17565644 16027843 18187930 12741479 17900296 14716496 16033810 12546737 18705752 18429990 15057751 14512876 16116963 15931870 18263696 18376398 17944888 17766677 18317297 12609069 13678700 12649538 17481882 12445421 16011737 17640975
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 9.2318166357
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 9.2318194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 9.2312878042
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.2312878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 9.2315078482 10677585 15288472 17127702 11172339 12891558 15362042 15334695 18380797 11682029 12557150 15465738 12175628 18416461 17355460 16098781 16511523 15288473 15158331 15474484 18032466 11481614 16343077 18263696 18615449 17629604 18458672 18606216 15716488 18395095 16489207 15095483 16248980 16097051 15316131 12085344 16126171 12531686 18031379 12679928 17292413 15075984 18295389 14739098 17050028
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 9.2316248980
MESH:D008107 Liver Diseases Acetaminophen 13.1719460945 11587558 12969438 16610002 19014921 12587719 16611625 19784758
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.1715720792 16964402 15830285 17285989 16246199
MESH:D008107 Liver Diseases DDT 13.1715729006
MESH:D008107 Liver Diseases Lindane 13.171715830
MESH:D008107 Liver Diseases Thioacetamide 13.1715158337 18374380 16337175
MESH:D008107 Liver Diseases Vitamin A 13.1716175620
MESH:D008108 Liver Diseases, Alcoholic Ethanol 9.5517207112 17347304
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 9.5516762690
MESH:D017093 Liver Failure Carbon Tetrachloride 3.5615123358
MESH:D017114 Liver Failure, Acute therapeutic 15313186
MESH:D017114 Liver Failure, Acute Acetaminophen 13.1316871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 13.1316899240 14706259
MESH:D017114 Liver Failure, Acute Thioacetamide 13.1315633222 17276928 15313186 12479984
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 8.4821295105 19389873
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 8.4819294768
MESH:D008113 Liver Neoplasms DDT 8.4815975961 11948501
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 8.4816984957
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 10.8018164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.8012014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.8012151625
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 10.8017113696
MESH:D008171 Lung Diseases 2-chloroethyl ethyl sulfide 10.1712815614 16252256 18675330
MESH:D008171 Lung Diseases Mustard Gas 10.1718702808 18161513
MESH:D008171 Lung Diseases Vitamin A 10.1716863852
MESH:D055370 Lung Injury Lipopolysaccharides 7.5721114838
MESH:D055370 Lung Injury Nitric Oxide 7.5711395602
MESH:D008175 Lung Neoplasms Acetaldehyde 4.1317372256
MESH:D008175 Lung Neoplasms Indomethacin 4.1311497255 11053908 16537180
MESH:D008175 Lung Neoplasms Mustard Gas 4.133148597 8781369
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.1311884234 19555203
MESH:D008223 Lymphoma Cyclophosphamide 6.6612854902
MESH:D008223 Lymphoma Nitric Oxide 6.6616166326
MESH:D016393 Lymphoma, B-Cell Cyclophosphamide 4.0316675587
MESH:D008228 Lymphoma, Non-Hodgkin Cyclophosphamide 3.6611911406
MESH:D008325 Mammary Neoplasms, Experimental Ibuprofen 3.3110697514
MESH:D008545 Melanoma Disulfiram 3.7915367699
MESH:D008545 Melanoma Glucose 3.7914993021
MESH:D008546 Melanoma, Experimental Acetaminophen 8.8319513568
MESH:D008546 Melanoma, Experimental Cyclophosphamide 8.8316388313
MESH:D008569 Memory Disorders Ethanol 3.6115451040 18411066
MESH:D008591 Meningomyelocele Homocysteine 4.9316602021
MESH:D008607 Mental Retardation Toluene 3.419294310
MESH:D024821 Metabolic Syndrome X Fructose 4.3016815490 17098227 18497449 19165636 17261469
MESH:D008881 Migraine Disorders Aspartame 10.3218627677 10792367
MESH:D008881 Migraine Disorders Indomethacin 10.3211903285
MESH:D008881 Migraine Disorders Nitric Oxide 10.3211701602
MESH:D020326 Migraine without Aura Nitric Oxide 4.5314659530 11304026
MESH:D019957 Motor Skills Disorders Toluene 4.669294310
MESH:D009062 Mouth Neoplasms Indomethacin 3.5112636206
MESH:D009101 Multiple Myeloma Vitamin A 3.6016374440
MESH:D009102 Multiple Organ Failure Zymosan 4.6412130978 10479408 15241586 15259001 18160304 12879239 15834315 17724436 10890648 15213630
MESH:D009128 Muscle Spasticity 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 5.4817220914
MESH:D018908 Muscle Weakness methamidophos 6.1517849254
MESH:D009203 Myocardial Infarction Homocysteine 5.6217412321
MESH:D009203 Myocardial Infarction Isoproterenol 5.6216697266 16584858 17052832 15740881 19595682 19172585 16538859
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.5212213967
MESH:D009216 Myopia Atropine 4.5912601066
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.2418551238
MESH:D009361 Neoplasm Invasiveness Disulfiram 4.7218047805
MESH:D009362 Neoplasm Metastasis Disulfiram 5.5315367699
MESH:D009362 Neoplasm Metastasis Indomethacin 5.5311053908 11239499 16537180
MESH:D009369 Neoplasms Aspartame 12.1816507461
MESH:D009369 Neoplasms Cyclophosphamide 12.1818854779
MESH:D009369 Neoplasms DDT 12.188820588
MESH:D009369 Neoplasms Disulfiram 12.1817079463
MESH:D009369 Neoplasms Lindane 12.1816818664 12807735
MESH:D009374 Neoplasms, Experimental Indomethacin 3.5415625704 10663608
MESH:D009389 Neovascularization, Pathologic Disulfiram 4.6515367699
MESH:D009395 Nephritis, Interstitial Ibuprofen 8.946375363
MESH:D009395 Nephritis, Interstitial Tetracycline 8.949884423
MESH:D009410 Nerve Degeneration Acrylamide 7.5812387367 11264303 12387366
MESH:D009410 Nerve Degeneration Ibuprofen 7.5810961664
MESH:D009422 Nervous System Diseases Acrylamide 8.7812164553 12507653
MESH:D009422 Nervous System Diseases methamidophos 8.782238440 15938848
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 2.6314600291
MESH:D009436 Neural Tube Defects Vitamin A 3.6417400914
MESH:D009447 Neuroblastoma Cyclophosphamide 3.2916115947 8761367 15176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.7118514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 6.7112349958
MESH:D017599 Neuroectodermal Tumors Cyclophosphamide 4.278761367 12837982
MESH:D020258 Neurotoxicity Syndromes Disulfiram 4.2111005259
MESH:D009503 Neutropenia Cyclophosphamide 7.648291058
MESH:D009503 Neutropenia Mustard Gas 7.647688884 16761898
MESH:D009669 Nose Neoplasms Formaldehyde 4.744038687
MESH:D009765 Obesity marker/mechanism 16289378
MESH:D009765 Obesity 2-chloroethyl ethyl sulfide 4.9316289378
MESH:D009765 Obesity Fructose 4.9317707055 18585860
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.546374098
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 2.8912819281 16049721
MESH:D009845 Oligospermia Cyclophosphamide 4.1016517039
MESH:D053578 Opsoclonus-Myoclonus Syndrome therapeutic 1318289
MESH:D010003 Osteoarthritis Aspartame 10.589630831
MESH:D010003 Osteoarthritis Ibuprofen 10.587009135
MESH:D010003 Osteoarthritis Indomethacin 10.587009135
MESH:D012516 Osteosarcoma Disulfiram 4.6818047805
MESH:D010051 Ovarian Neoplasms Disulfiram 3.5417026967
MESH:D010146 Pain Acetaminophen 19.9716870215
MESH:D010146 Pain Aspartame 19.979630831
MESH:D010146 Pain Cyclophosphamide 19.9712161096 18093676
MESH:D010146 Pain Ibuprofen 19.973291741
MESH:D010146 Pain Indomethacin 19.9717627676 3291741 17440234 13679232
MESH:D010146 Pain Morphine 19.976776300 18699797 16273134 15275824 15215642 20225289
MESH:D010149 Pain, Postoperative Ibuprofen 9.3916678543
MESH:D010149 Pain, Postoperative Indomethacin 9.3918702446 12538197
MESH:D010190 Pancreatic Neoplasms Cyclophosphamide 7.3511332152
MESH:D010190 Pancreatic Neoplasms Ethanol 7.3512384795
MESH:D010190 Pancreatic Neoplasms Ibuprofen 7.3512384795
MESH:D010195 Pancreatitis Indomethacin 3.3617883296 15028970
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.1111578682
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.0916537180
MESH:D010300 Parkinson Disease Homocysteine 3.3216275827
MESH:D020734 Parkinsonian Disorders Indomethacin 3.5812349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.0911903285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.6212520081
MESH:D010391 Pemphigoid, Bullous Tetracycline 4.8011026799
MESH:D010437 Peptic Ulcer Indomethacin 4.5311148446
MESH:D010518 Periodontitis Indomethacin 4.2917225004
MESH:D010523 Peripheral Nervous System Diseases Acrylamide 8.9911510240
MESH:D010523 Peripheral Nervous System Diseases methamidophos 8.9910447555 7654138 2170085
MESH:D010538 Peritonitis Zymosan 4.2814761945 18557954 11985352 18977430 17371808 17826846 15979727 15259001 18760300 19088179 19641140
MESH:D047748 Pituitary ACTH Hypersecretion marker/mechanism 16809932
MESH:D011014 Pneumonia Lipopolysaccharides 3.9412224865 11605937
MESH:D011015 Pneumonia, Aspiration Nitric Oxide 4.7218573544
MESH:D011041 Poisoning Atropine 11.6217849254 18072136
MESH:D011041 Poisoning methamidophos 11.6216119251 17849254
MESH:D011041 Poisoning Mustard Gas 11.6215727166
MESH:D011115 Polyneuropathies methamidophos 5.477654138
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 2.9718163543
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Cyclophosphamide 3.4321297632
MESH:D047928 Premature Birth Indomethacin 4.5217000239
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.5811118676 11222880 11896295 11399792
MESH:D017096 Prion Diseases Tetracycline 4.7910903871
OMIM:609734 PROOPIOMELANOCORTIN DEFICIENCY marker/mechanism
MESH:D011471 Prostatic Neoplasms Cyclophosphamide 2.0417136230
MESH:D011471 Prostatic Neoplasms DDT 2.0412584743
MESH:D011471 Prostatic Neoplasms Disulfiram 2.0419789329
MESH:D011471 Prostatic Neoplasms Ibuprofen 2.0417409433
MESH:D011471 Prostatic Neoplasms Lindane 2.0414688026 12661182
MESH:D011507 Proteinuria Ibuprofen 7.826375363
MESH:D011507 Proteinuria Indomethacin 7.8211849393
MESH:D011537 Pruritus Ethinyl Estradiol 7.4915861022 16919318
MESH:D011537 Pruritus Mustard Gas 7.4918058305
MESH:D011629 Puberty, Precocious astressin B 6.2420002962
MESH:D011654 Pulmonary Edema Isoproterenol 4.6210903255
MESH:D011658 Pulmonary Fibrosis Cyclophosphamide 5.0716636934
MESH:D011658 Pulmonary Fibrosis Mustard Gas 5.0717266442 10334151 17894541 17620002 17720292
MESH:D012021 Reflex, Abnormal Pentobarbital 5.4010930210
MESH:D015427 Reperfusion Injury Morphine 3.8019211983
MESH:D012128 Respiratory Distress Syndrome, Adult 2-chloroethyl ethyl sulfide 4.5416292752 18257742 12210543
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.1816877224
MESH:D012130 Respiratory Hypersensitivity Acetylcholine 7.129413022
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 7.1210835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.2518990726
MESH:D012220 Rhinitis Acetaldehyde 4.2117050345
MESH:D012555 Schistosomiasis mansoni Nitric Oxide 4.869673227
MESH:D012559 Schizophrenia Homocysteine 3.0116641680
MESH:D012595 Scleroderma, Systemic Cyclophosphamide 9.8516636934
MESH:D012595 Scleroderma, Systemic Formaldehyde 9.8514979077
MESH:D012640 Seizures 2,4-dinitrotoluene 21.4518551238
MESH:D012640 Seizures Atropine 21.4512660363 17157343 11218047
MESH:D012640 Seizures Clonidine 21.4510087439
MESH:D012640 Seizures Ethanol 21.459754883
MESH:D012640 Seizures Lindane 21.4515475178 7539098 12842176
MESH:D012640 Seizures Pentobarbital 21.459754883 10087439
MESH:D012640 Seizures Toluene 21.459294310 6431079
MESH:D018805 Sepsis Zymosan 4.1411441115
MESH:D012852 Sinusitis Phenylephrine 4.097327846
MESH:D012859 Sjogren's Syndrome Aspartame 5.9516800424
MESH:D012871 Skin Diseases Mustard Gas 4.6816961503 12880345 15451306
MESH:D012871 Skin Diseases Vitamin A 4.6818709164
MESH:D012878 Skin Neoplasms Glucose 4.8814993021
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 4.8816192470
MESH:D007319 Sleep Initiation and Maintenance Disorders Clonidine 5.0918280681
MESH:D013088 Spermatocele Ethinyl Estradiol 3.3116709447
OMIM:102530 SPERMATOGENIC FAILURE 6 Cyclophosphamide 4.9016517039
MESH:D013272 Stomach Diseases Indomethacin 3.8110192188 15472012 18545984 17160473 10486359 17207306 16280098 16113693 17638125 15038085 16184426 18209964 10215738
MESH:D013274 Stomach Neoplasms Ethanol 2.6318456281
MESH:D013274 Stomach Neoplasms Indomethacin 2.6315609394
MESH:D013276 Stomach Ulcer Atropine 12.8411595415
MESH:D013276 Stomach Ulcer Ethanol 12.8417189318 11906479 9562338 16755016 17918041 9211565
MESH:D013276 Stomach Ulcer Indomethacin 12.8412787963 12077510 11729361 17895592 17654042 1323529 18726076 17627676 12467913 17135157 12500499 17977527 11595415 16631530 10750652 10878458 11145282 15104355 12498302 18193104 18087811 16397915 16169175 16755016 14567935 11595431 18181030 18543354 16150113 15138204 18209962 18431645 16252198 17657623 15255614 16934674 18299717 11906479 11523592 17918041 18237397 10423059
MESH:D013276 Stomach Ulcer Nitric Oxide 12.8415138204
MESH:D013375 Substance Withdrawal Syndrome Ethanol 8.469754883
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 8.4611529278 9754883
MESH:D015173 Supratentorial Neoplasms Cyclophosphamide 4.4412837982
MESH:D013733 Testicular Diseases Acrylamide 8.9615864552
MESH:D013733 Testicular Diseases Toluene 8.9610514026 10048760
MESH:D013921 Thrombocytopenia Aspartame 8.5217534100
MESH:D013921 Thrombocytopenia Lipopolysaccharides 8.5215821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.0511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.6315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.2712697716
MESH:D013964 Thyroid Neoplasms Indomethacin 3.1214736730 18791128 11352223
MESH:D014202 Tremor Atropine 5.1017594079
MESH:D014456 Ulcer Indomethacin 4.2810574470 17380554
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 4.3916049721
MESH:D001749 Urinary Bladder Neoplasms Cyclophosphamide 4.3914692829
MESH:D014570 Urologic Diseases DDT 5.0116487989
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.7010091137
MESH:D014581 Urticaria Acetaminophen 2.4110982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.7214692618
MESH:D014605 Uveitis Zymosan 4.7711006244
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 3.9612125929
MESH:D020301 Vasospasm, Intracranial Ibuprofen 10.1219057314
MESH:D020301 Vasospasm, Intracranial Nitric Oxide Donors 10.1219057314
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 2.9815869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Isoproterenol 4.5218097624
MESH:D020257 Ventricular Remodeling Isoproterenol 5.0718097624
MESH:D014802 Vitamin A Deficiency Vitamin A 4.7016175781 16960172 16146918
MESH:D014839 Vomiting Indomethacin 4.1211897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.6215886252
Pathway ID Pathway Name
KEGG:04920 Adipocytokine signaling pathway
REACT:15314 Hormone biosynthesis
KEGG:04916 Melanogenesis
REACT:13 Metabolism of amino acids and derivatives
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:15295 Opioid Signalling
REACT:14797 Signaling by GPCR
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33526
    • No data
    Releated disease ID Related disease Name
    PA447199Bipolar Disorder
    PA443264Addison Disease
    Releated drug ID Related drug Name
    PA164768822chlorotrianisene
    PA164754789conjugated estrogens
    PA164745534dienestrol
    PA449307diethylstilbestrol
    PA449503estradiol
    PA449509estrogens
    PA449512estrone
    PA449527ethinyl estradiol
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00836 modulator Loperamide Antidiarrheals
    DB01497 - Etorphine Hypnotics and Sedatives;Narcotics;Analgesics, Opioid
    DB01565 agonist Dihydromorphine Narcotics;Analgesics, Opioid
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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