Annotation Detail for SH3TC1
Basic Information
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| Gene Symbol: | SH3TC1 ( FLJ20356,FLJ32999,FLJ36243,FLJ46394 ) |
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| Gene Full Name: | SH3 domain and tetratricopeptide repeats 1 |
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| Band: | 4p16.1 |
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| Quick Links | Entrez ID:54436; OMIM: NA; Uniprot ID:S3TC1_HUMAN; ENSEMBL ID: ENSG00000125089; HGNC ID: 26009 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of SH3TC1 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of SH3TC1 mRNA | affects expression | 17562736
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of SH3TC1 mRNA | increases expression | 20106945
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of SH3TC1 mRNA | increases expression | 16002434
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.57 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.56 | 11237771 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
2.96 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
2.96 | 3084413 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
2.71 | 11237771 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.79 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.79 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.21 | 19486331 |
| MESH:D015179 |
Colorectal Neoplasms |
marker/mechanism |
|
| 21278247 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.58 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.02 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.02 | 10774834 10915739 2444490 18713872 19370779 11743745 16227642 19085960 16109766 15968718 16081117 18071297 12958197 19416960 17562736 17522070 16177239 16781746 14550746 11461765 12594235 11739529 14986274 17906064 12392966 12705907 11834606 14725611 10663392 11421492 16485898 12153990 19164858 11287661 11529661 19739265 19923254 12540782 16393943 19420014 15619225 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.82 | 19426721 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
4.44 | 15138306 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.28 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.70 | 12639820 12168785 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.40 | 16983495 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.85 | 8708960 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.05 | 15720958 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.02 | 16870215 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.21 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.16 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.48 | 12587719 15629191 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
6.48 | 10903974 18776723 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.44 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
8.44 | 12371664 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.70 | 12969438 12587719 16611625 19784758 16610002 19014921 11587558 19460945 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.63 | 16871587 17185352 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.13 | 19513568 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.51 | 16801185 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.49 | 18551238 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.16 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.65 | 19348381 18481113 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.21 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
3.82 | 12819281 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.73 | 16870215 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.59 | 12371664 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.41 | 15572423 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.48 | 18247401 16289102 15754350 12479363 16644109 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.33 | 16882103 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
2.79 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.41 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.95 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.44 | 10982225 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.71 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.16 | 17120751 |
PharmGKB Accession:PA128394666
| Releated disease ID |
Related disease Name |
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
Related Pathway Information