Annotation Detail for SMCR7L
Basic Information
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| Gene Symbol: | SMCR7L ( FLJ20232,HSU79252,dJ1104E15.3 ) |
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| Gene Full Name: | Smith-Magenis syndrome chromosome region, candidate 7-like |
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| Band: | 22q13 |
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| Quick Links | Entrez ID:54471; OMIM: NA; Uniprot ID:SMC7L_HUMAN; ENSEMBL ID: ENSG00000100335; HGNC ID: |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C075773 |
4-phenylbutyric acid |
4-phenylbutyric acid results in decreased expression of SMCR7L mRNA | decreases expression | 14583596
|
| D001194 |
Asbestos |
Asbestos affects the expression of SMCR7L mRNA | affects expression | 17297452
|
| D013749 |
Tetrachlorodibenzodioxin |
[Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of SMCR7L mRNA | affects cotreatment|decreases expression | 19465110
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Tetrachlorodibenzodioxin |
3.59 | 11752688 15322242 14514962 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Tetrachlorodibenzodioxin |
4.12 | 16835633 |
| MESH:D000740 |
Anemia |
|
Tetrachlorodibenzodioxin |
3.39 | 11748828 |
| MESH:D050197 |
Atherosclerosis |
|
Asbestos |
4.45 | 18795166 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
Tetrachlorodibenzodioxin |
3.53 | 12125929 |
| MESH:D001836 |
Body Weight Changes |
|
Tetrachlorodibenzodioxin |
4.66 | 15340226 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Tetrachlorodibenzodioxin |
3.02 | 15746008 |
| MESH:D001943 |
Breast Neoplasms |
|
Tetrachlorodibenzodioxin |
1.66 | 20435547 |
| MESH:D002277 |
Carcinoma |
|
Tetrachlorodibenzodioxin |
3.16 | 16835633 |
| MESH:D006332 |
Cardiomegaly |
|
Tetrachlorodibenzodioxin |
2.58 | 18670907 18850075 16120746 |
| MESH:D018281 |
Cholangiocarcinoma |
|
Tetrachlorodibenzodioxin |
3.58 | 16835633 |
| MESH:D002972 |
Cleft Palate |
|
Tetrachlorodibenzodioxin |
2.25 | 15340226 12621046 8697196 15668235 16354765 |
| MESH:D000013 |
Congenital Abnormalities |
|
Tetrachlorodibenzodioxin |
3.48 | 17141729 14669216 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Tetrachlorodibenzodioxin |
1.27 | 20055451 10048152 15322242 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Tetrachlorodibenzodioxin |
1.74 | 17107852 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Tetrachlorodibenzodioxin |
1.62 | 20420201 |
| MESH:D004362 |
Drug Toxicity |
|
Tetrachlorodibenzodioxin |
3.09 | 11462148 |
| MESH:D004487 |
Edema |
|
Tetrachlorodibenzodioxin |
2.85 | 12711302 11000095 |
| MESH:D004489 |
Edema, Cardiac |
|
Tetrachlorodibenzodioxin |
4.77 | 18230668 16714409 15322242 |
| MESH:D004715 |
Endometriosis |
|
Tetrachlorodibenzodioxin |
3.47 | 9294722 10568697 |
| MESH:D005124 |
Eye Abnormalities |
|
Tetrachlorodibenzodioxin |
3.34 | 11564622 |
| MESH:D005313 |
Fetal Death |
|
Tetrachlorodibenzodioxin |
4.11 | 11858732 |
| MESH:D005355 |
Fibrosis |
|
Tetrachlorodibenzodioxin |
3.60 | 20067830 |
| MESH:D006058 |
Gonadal Disorders |
|
Tetrachlorodibenzodioxin |
5.46 | 10696789 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Tetrachlorodibenzodioxin |
2.53 | 11294989 10048152 |
| MESH:D006470 |
Hemorrhage |
|
Tetrachlorodibenzodioxin |
3.82 | 11000095 |
| MESH:D006529 |
Hepatomegaly |
|
Tetrachlorodibenzodioxin |
3.54 | 15340226 12621046 16120746 |
| MESH:D006869 |
Hydronephrosis |
|
Tetrachlorodibenzodioxin |
4.91 | 16354765 15340226 8697196 18606429 16959395 |
| MESH:D006973 |
Hypertension |
|
Tetrachlorodibenzodioxin |
2.03 | 18850075 18670907 |
| MESH:D007249 |
Inflammation |
|
Tetrachlorodibenzodioxin |
2.04 | 12878042 12200463 |
| MESH:D007569 |
Jaw Abnormalities |
|
Tetrachlorodibenzodioxin |
3.82 | 16580747 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tetrachlorodibenzodioxin |
1.25 | 12878042 |
| MESH:D008113 |
Liver Neoplasms |
|
Tetrachlorodibenzodioxin |
1.84 | 16984957 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Tetrachlorodibenzodioxin |
2.35 | 12151625 |
| MESH:D008175 |
Lung Neoplasms |
|
Asbestos |
2.87 | 12111688 |
| MESH:D008175 |
Lung Neoplasms |
|
Tetrachlorodibenzodioxin |
2.87 | 11884234 19555203 |
| MESH:D008654 |
Mesothelioma |
|
Asbestos |
4.22 | 16919927 18709470 16564556 18310086 16319530 |
| MESH:D017202 |
Myocardial Ischemia |
|
Tetrachlorodibenzodioxin |
3.38 | 12213967 |
| MESH:D009369 |
Neoplasms |
|
4-phenylbutyric acid |
3.89 | 19116145 |
| MESH:D009421 |
Nervous System Malformations |
|
Tetrachlorodibenzodioxin |
3.80 | 14600291 |
| MESH:D010382 |
Peliosis Hepatis |
|
Tetrachlorodibenzodioxin |
5.12 | 12520081 |
| MESH:D017119 |
Porphyria Cutanea Tarda |
|
Tetrachlorodibenzodioxin |
4.14 | 18163543 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Tetrachlorodibenzodioxin |
3.93 | 11399792 11896295 11118676 11222880 |
| MESH:D015619 |
Respiratory System Abnormalities |
|
Tetrachlorodibenzodioxin |
4.42 | 18990726 |
| MESH:D012878 |
Skin Neoplasms |
|
Tetrachlorodibenzodioxin |
2.21 | 16192470 |
| MESH:D013959 |
Thyroid Diseases |
|
Tetrachlorodibenzodioxin |
4.77 | 12697716 |
| MESH:D054079 |
Vascular Malformations |
|
Tetrachlorodibenzodioxin |
5.46 | 12125929 |
| MESH:D019282 |
Wasting Syndrome |
|
Tetrachlorodibenzodioxin |
5.12 | 15886252 |
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