Gene Symbol:	HEATR5B ( KIAA1414 )
Gene Full Name:	HEAT repeat containing 5B
Band:	2p22.2
Quick Links	Entrez ID:54497; OMIM: NA; Uniprot ID:HTR5B_HUMAN; ENSEMBL ID: ENSG00000008869; HGNC ID: 29273
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of HEATR5B mRNA	decreases expression	19150397
D006830	Hydralazine	[Hydralazine co-treated with Valproic Acid] results in decreased expression of HEATR5B mRNA	affects cotreatment\|decreases expression	17183730
D014635	Valproic Acid	[Hydralazine co-treated with Valproic Acid] results in decreased expression of HEATR5B mRNA	affects cotreatment\|decreases expression	17183730

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000014	Abnormalities, Drug-Induced	Valproic Acid	4.23	8875741
MESH:D000015	Abnormalities, Multiple	Valproic Acid	4.41	19490988
MESH:D000550	Amblyopia	Valproic Acid	6.10	17688650
MESH:D001008	Anxiety Disorders	Valproic Acid	3.94	17497229
MESH:D001321	Autistic Disorder	Valproic Acid	1.98	18177632 18316065 17688650 17507914 16609825 20603192 18775368 18985861 18940202 18558336 17157402 15238991 19232924 18396377 19460635
MESH:D001714	Bipolar Disorder	Valproic Acid	3.26	20046352 17594078
MESH:D001848	Bone Diseases, Developmental	Valproic Acid	3.66	8888407
MESH:D002471	Cell Transformation, Neoplastic	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	3.01	20889678
MESH:D002659	Child Development Disorders, Pervasive	Valproic Acid	2.83	20734317
MESH:D019465	Craniofacial Abnormalities	Valproic Acid	1.91	16575769 8888407 17688650
MESH:D056486	Drug-Induced Liver Injury	Valproic Acid	2.26	19641884 1733752
MESH:D004421	Dystonia	Valproic Acid	4.58	1851702
MESH:D004831	Epilepsies, Myoclonic	Valproic Acid	4.81	17275665 3659116
MESH:D004828	Epilepsies, Partial	Valproic Acid	4.78	3922381 16628512
MESH:D004827	Epilepsy	Valproic Acid	3.12	20417680 18234410
MESH:D004832	Epilepsy, Absence	Valproic Acid	4.00	7562514 6426943 6254150
MESH:D017029	Epilepsy, Complex Partial	Valproic Acid	4.95	7750514
MESH:D004830	Epilepsy, Tonic-Clonic	Valproic Acid	4.81	3659116
MESH:D004938	Esophageal Neoplasms	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	2.15	20426865
MESH:D005234	Fatty Liver	Valproic Acid	3.78	19224547 14986274
MESH:D005315	Fetal Diseases	Valproic Acid	5.75	16575769
MESH:D005317	Fetal Growth Retardation	Valproic Acid	4.71	8888407 18558336
MESH:D006849	Hydrocephalus	Valproic Acid	5.61	17688650
MESH:D046110	Hypertension, Pregnancy-Induced	Hydralazine	5.28	16612254
MESH:D015470	Leukemia, Myeloid, Acute	Valproic Acid	2.20	16294345 17596541
MESH:D017563	Lung Diseases, Interstitial	Valproic Acid	5.13	17228818
MESH:D008881	Migraine Disorders	Valproic Acid	3.50	18803445 18765137
MESH:D009139	Musculoskeletal Abnormalities	Valproic Acid	4.51	8888407
MESH:D009190	Myelodysplastic Syndromes	Valproic Acid	3.37	17596541
MESH:D009436	Neural Tube Defects	Valproic Acid	3.39	16359493 8888407
MESH:D011297	Prenatal Exposure Delayed Effects	Valproic Acid	4.57	20603192
MESH:D019310	Pseudolymphoma	Valproic Acid	5.41	12752131 11422049
MESH:D012208	Rhabdomyosarcoma	Valproic Acid	4.70	19155313
MESH:D012559	Schizophrenia	Valproic Acid	2.11	15737665 19110320
MESH:D012640	Seizures	Valproic Acid	3.02	15475178 11044598 17978042 14763951 16876388 3137016 11738929 1511512
MESH:D016135	Spinal Dysraphism	Valproic Acid	4.13	19490988
MESH:D013226	Status Epilepticus	Valproic Acid	5.41	12833885
MESH:D014178	Translocation, Genetic	Valproic Acid	6.10	17262798
MESH:D020194	Unverricht-Lundborg Syndrome	Valproic Acid	5.26	3119515
MESH:D014564	Urogenital Abnormalities	Valproic Acid	5.30	8888407

AutismKB 2.0

Annotation Detail for HEATR5B

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics