Annotation Detail for L1TD1
Basic Information
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| Gene Symbol: | L1TD1 ( ECAT11,FLJ10884,MGC133253,RP5-1155K23.3 ) |
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| Gene Full Name: | LINE-1 type transposase domain containing 1 |
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| Band: | 1p31.3 |
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| Quick Links | Entrez ID:54596; OMIM: NA; Uniprot ID:LITD1_HUMAN; ENSEMBL ID: ENSG00000240563; HGNC ID: 25595 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C014347 |
decitabine |
decitabine results in decreased methylation of L1TD1 promoter | decreases methylation | 19421002
|
| D005472 |
Fluorouracil |
TP53 protein affects the reaction [Fluorouracil results in decreased expression of L1TD1 mRNA] | affects reaction|decreases expression | 15016801
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
Fluorouracil |
2.51 | 17638652 |
| MESH:D000740 |
Anemia |
|
Fluorouracil |
4.22 | 17963324 16511603 15504547 |
| MESH:D001943 |
Breast Neoplasms |
|
decitabine |
2.34 | 19208741 18320071 |
| MESH:D001943 |
Breast Neoplasms |
|
Fluorouracil |
2.34 | 15136595 16595493 19217205 16557594 18357371 16110121 18608205 |
| MESH:D002276 |
Carcinoid Tumor |
|
Fluorouracil |
5.74 | 16051944 |
| MESH:D002277 |
Carcinoma |
|
Fluorouracil |
3.97 | 17121937 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Fluorouracil |
2.12 | 17045692 17971768 16332177 17088986 18930000 16799960 |
| MESH:D002292 |
Carcinoma, Renal Cell |
|
Fluorouracil |
3.20 | 18695887 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
decitabine |
5.20 | 19215824 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Fluorouracil |
5.20 | 18986760 16280240 17066447 16757204 |
| MESH:D003110 |
Colonic Neoplasms |
|
decitabine |
4.09 | 17616700 |
| MESH:D003110 |
Colonic Neoplasms |
|
Fluorouracil |
4.09 | 17725105 17287894 15001691 18772588 16510598 16340194 17016597 17169374 17172411 17018589 |
| MESH:D015179 |
Colorectal Neoplasms |
|
decitabine |
2.72 | 18981723 |
| MESH:D015179 |
Colorectal Neoplasms |
|
Fluorouracil |
2.72 | 15148649 17255274 18383874 15289873 16303861 17094418 16282729 18288408 17695437 17594712 17454858 17016601 18802399 18949393 20501625 18448328 16331619 14970324 17401013 16391804 18509181 16524972 |
| MESH:D007644 |
Darier Disease |
|
Fluorouracil |
5.68 | 16733453 |
| MESH:D004701 |
Endocrine Gland Neoplasms |
|
decitabine |
6.19 | 19294695 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Fluorouracil |
2.54 | 16337965 16481741 15173087 16785472 17638652 |
| MESH:D005910 |
Glioma |
|
Fluorouracil |
3.02 | 16145905 |
| MESH:D006258 |
Head and Neck Neoplasms |
|
decitabine |
8.95 | 19215824 |
| MESH:D006258 |
Head and Neck Neoplasms |
|
Fluorouracil |
8.95 | 15162350 15102660 18337622 |
| MESH:D007248 |
Infertility, Male |
|
decitabine |
3.51 | 17581917 |
| MESH:D007680 |
Kidney Neoplasms |
|
Fluorouracil |
3.74 | 16985049 |
| MESH:D007938 |
Leukemia |
|
decitabine |
3.27 | 18980019 19235587 |
| MESH:D007951 |
Leukemia, Myeloid |
|
decitabine |
4.55 | 18454857 19117987 17236224 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
decitabine |
2.44 | 18206229 19010910 19387464 18460780 18704418 17679729 |
| MESH:D015477 |
Leukemia, Myelomonocytic, Chronic |
|
decitabine |
6.53 | 18055864 |
| MESH:D008113 |
Liver Neoplasms |
|
Fluorouracil |
2.62 | 15113037 17045692 16603448 18383874 |
| MESH:D008175 |
Lung Neoplasms |
|
Fluorouracil |
2.01 | 15246190 |
| MESH:D008178 |
Lupus Erythematosus, Cutaneous |
|
Fluorouracil |
5.68 | 15086387 |
| MESH:D008223 |
Lymphoma |
|
decitabine |
3.76 | 19470736 |
| MESH:D008545 |
Melanoma |
|
decitabine |
2.29 | 16505122 17785578 |
| MESH:D009062 |
Mouth Neoplasms |
|
Fluorouracil |
4.02 | 18986760 16757204 |
| MESH:D009101 |
Multiple Myeloma |
|
decitabine |
3.69 | 18172295 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
decitabine |
3.62 | 19010910 16882708 19157545 18608210 |
| MESH:D009369 |
Neoplasms |
|
decitabine |
5.95 | 19116145 17925555 19470736 |
| MESH:D009369 |
Neoplasms |
|
Fluorouracil |
5.95 | 16928823 18239605 18600527 |
| MESH:D020258 |
Neurotoxicity Syndromes |
|
Fluorouracil |
3.75 | 16436463 |
| MESH:D010051 |
Ovarian Neoplasms |
|
decitabine |
2.76 | 19259094 19331143 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
decitabine |
5.91 | 19294695 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Fluorouracil |
5.91 | 19003803 16929163 16500647 15113037 |
| MESH:D055728 |
Primary Myelofibrosis |
|
decitabine |
5.49 | 17616702 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Fluorouracil |
3.34 | 18626508 19082440 |
| MESH:D012004 |
Rectal Neoplasms |
|
Fluorouracil |
4.48 | 16160472 18722050 15538739 18286688 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
decitabine |
5.01 | 19155313 |
| MESH:D013274 |
Stomach Neoplasms |
|
decitabine |
2.71 | 19037991 |
| MESH:D013274 |
Stomach Neoplasms |
|
Fluorouracil |
2.71 | 17522103 17172411 16424979 17498489 18396642 19015929 18567086 19084572 16951190 15786421 |
| MESH:D013964 |
Thyroid Neoplasms |
|
decitabine |
3.71 | 17967635 |
| MESH:D014062 |
Tongue Neoplasms |
|
Fluorouracil |
4.50 | 16280240 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
decitabine |
2.86 | 17616700 19087683 |
| MESH:D002583 |
Uterine Cervical Neoplasms |
|
Fluorouracil |
4.38 | 16803524 |
| MESH:D014604 |
Uveal Neoplasms |
|
decitabine |
5.98 | 17785578 |
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