AutismKB 2.0

Annotation Detail for CCNJ


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Basic Information Top
Gene Symbol:CCNJ ( bA690P14.1 )
Gene Full Name: cyclin J
Band: 10q24.1
Quick LinksEntrez ID:54619; OMIM: NA; Uniprot ID:CCNJ_HUMAN; ENSEMBL ID: ENSG00000107443; HGNC ID: 23434
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001241 Aspirin Aspirin results in increased expression of CCNJ mRNAincreases expression 11906190
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CCNJ mRNAdecreases expression 20106945
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of CCNJ mRNAincreases expression 15336504
C410733 scriptaid scriptaid affects the expression of CCNJ mRNAaffects expression 18813790
D013467 Sulindac Sulindac results in decreased expression of CCNJ mRNAdecreases expression 11906190
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CCNJ mRNAdecreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 6.0214745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.3114514962 11752688 15322242
MESH:D058186 Acute Kidney Injury Sulindac 4.647897758
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.8720464547 20127859
MESH:D000230 Adenocarcinoma Sulindac 4.8711910360
MESH:D000236 Adenoma Benzo(a)pyrene 7.536695378
MESH:D000236 Adenoma Sulindac 7.5310223192
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.8416835633
MESH:D011125 Adenomatous Polyposis Coli Sulindac 4.9019003578 12394442 15623613 11874996 17611924 11535846 16460482
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2511748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D055963 Asthma, Aspirin-Induced Aspirin 4.9720485159 12372130
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.3712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.3115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9515746008
MESH:D001913 Bowen's Disease Sulindac 5.8711207687
MESH:D001932 Brain Neoplasms Aspirin 4.7215481559
MESH:D001943 Breast Neoplasms Aspirin 2.0515161893
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0520146248 17474063
MESH:D001943 Breast Neoplasms Sulindac 2.0516642371
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0520435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0516835633
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5218850075 16120746 18670907
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4516835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2115668235 15340226 16354765 8697196 12621046
MESH:D003110 Colonic Neoplasms Aspirin 4.5212411196
MESH:D003110 Colonic Neoplasms Sulindac 4.5212902858 12458338
MESH:D015179 Colorectal Neoplasms Aspirin 3.1817047198
MESH:D015179 Colorectal Neoplasms Sulindac 3.1811197048 11076880 18059344 10666051
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3417141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2615322242 20055451 10048152
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7217107852
MESH:D003930 Diabetic Retinopathy Sulindac 5.5617621415 12861449
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 1.6020420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9911462148
MESH:D004487 Edema Aspirin 8.1517259670
MESH:D004487 Edema Tetrachlorodibenzodioxin 8.1512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.4215322242 16714409 18230668
MESH:D004715 Endometriosis Sulindac 10.2215652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 10.229294722 10568697
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.9616530937
MESH:D004938 Esophageal Neoplasms Sulindac 4.9612235107
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2411564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.8711858732
MESH:D018221 Fibromatosis, Abdominal Sulindac 5.9414745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 5.5919069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.3620067830
MESH:D005764 Gastroesophageal Reflux Sulindac 5.3911910360
MESH:D005909 Glioblastoma Aspirin 4.1412870263
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.1210696789
MESH:D006261 Headache Aspirin 5.4815240983
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.9320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.9311294989 10048152
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.6611000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.3116120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.578697196 16959395 15340226 18606429 16354765
MESH:D012001 Hyperacusis Aspirin 6.2815240983
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0018670907 18850075
MESH:D007249 Inflammation Sulindac 5.723291741
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.7212200463 12878042
MESH:D007414 Intestinal Neoplasms Sulindac 4.9412663524 12351151 12584176 12628509 10223192 10213222
MESH:D007417 Intestinal Polyps Sulindac 5.3411245490 12394442
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.6616580747
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 4.4012468960
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008107 Liver Diseases Sulindac 3.0916867024 14986274
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.6620195826 21137059
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.6616984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.2812151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.6320064080 20464547 18569708 18520028 6695378 17053015 20135361 18816296 20869020
MESH:D008175 Lung Neoplasms Sulindac 3.6315713900 19359593
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.6311884234 19555203
MESH:D008545 Melanoma Sulindac 2.8616642371
MESH:D008881 Migraine Disorders Aspirin 4.2815240983
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009203 Myocardial Infarction Aspirin 3.6612692751
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2712213967
MESH:D009325 Nausea Aspirin 5.7315240983
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.5914600291
MESH:D019636 Neurodegenerative Diseases Sulindac 4.5417266991 16850258
MESH:D010003 Osteoarthritis Aspirin 4.237009135
MESH:D010146 Pain Aspirin 8.356995502 6363464
MESH:D010146 Pain Sulindac 8.353291741
MESH:D010190 Pancreatic Neoplasms Sulindac 3.4416820089 11504793
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.7712520081
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 6.0011156591
MESH:D020795 Photophobia Aspirin 6.2815240983
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.9418163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.6511896295 11118676 11399792 11222880
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9217292933
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.2218990726
MESH:D012220 Rhinitis Aspirin 4.6812372130
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 5.6812269725
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 10.1510029692 19755658
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 10.158532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 10.1516192470
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D020521 Stroke Aspirin 4.6316403987
MESH:D013927 Thrombosis Aspirin 4.8017672075
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.4212697716
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2817053015
MESH:D014581 Urticaria Aspirin 4.7910982225 20485159
MESH:D014594 Uterine Neoplasms Sulindac 4.9818645019
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.1212125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.7715886252
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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