AutismKB 2.0

Annotation Detail for ARL15


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Basic Information Top
Gene Symbol:ARL15 ( ARFRP2,FLJ20051 )
Gene Full Name: ADP-ribosylation factor-like 15
Band: 5q11.2
Quick LinksEntrez ID:54622; OMIM: NA; Uniprot ID:ARL15_HUMAN; ENSEMBL ID: ENSG00000185305; HGNC ID: 25945
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
METABOLIC
Adiponectin levels
Desease Name
Adiponectin levels
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ARL15 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ARL15 proteinaffects expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ARL15 mRNAdecreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ARL15 mRNAdecreases expression 20713471
D016572 Cyclosporine Cyclosporine results in decreased expression of ARL15 mRNAdecreases expression 20106945
D009151 Mustard Gas Mustard Gas affects the expression of ARL15 mRNAaffects expression 15651846
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001249 Asthma Mustard Gas 2.7910378619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001768 Blister Mustard Gas 5.7019167455
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0020146248 17474063
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.7015286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.5917687719 10378619
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.023084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 3.0212907637 12619106 21507988
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7612371664
MESH:D002779 Cholestasis Cyclosporine 3.1719486331
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6619923254 10774834 12958197 12153990 11834606 12540782 16177239 12392966 14986274 10663392 16227642 18713872 15619225 16393943 16081117 17562736 19420014 19370779 16109766 16485898 19164858 14550746 17906064 11529661 15968718 11287661 11421492 11743745 2444490 10915739 17522070 18071297 12594235 11461765 19085960 16781746 19416960 12705907 14725611 19739265 11739529
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004487 Edema Mustard Gas 3.679260866 11428647 11428631 11402378
MESH:D004890 Erythema Mustard Gas 5.709357497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Cyclosporine 3.2319224547
MESH:D005355 Fibrosis Cyclosporine 3.6212639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007249 Inflammation Mustard Gas 2.9417524151 11402378 8975870 9260866 9357497 11428647 11428631 16001271 11428620
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Acetaminophen 6.4112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 6.418314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0412371664
MESH:D008107 Liver Diseases Acetaminophen 1.6919014921 12969438 19460945 16611625 11587558 19784758 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.932125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.9321137059 20195826
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.948603461
MESH:D008171 Lung Diseases Mustard Gas 3.6718161513 18702808
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.6614755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.6618569708 18520028 18816296 20464547 20135361 17053015 20064080 6695378 20869020
MESH:D008175 Lung Neoplasms Mustard Gas 3.663148597 8781369
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6119348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009503 Neutropenia Mustard Gas 4.3716761898 7688884
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011041 Poisoning Mustard Gas 4.2015727166
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D011537 Pruritus Mustard Gas 4.6318058305
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0317894541 17720292 17620002 17266442 10334151
MESH:D012871 Skin Diseases Mustard Gas 2.7812880345 15451306 16961503
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5110029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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