AutismKB 2.0

Annotation Detail for PPARD


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Basic Information Top
Gene Symbol:PPARD ( FAAR,MGC3931,NR1C2,NUC1,NUCI,NUCII,PPARB )
Gene Full Name: peroxisome proliferator-activated receptor delta
Band: 6p21.31
Quick LinksEntrez ID:5467; OMIM: 600409; Uniprot ID:PPARD_HUMAN; ENSEMBL ID: ENSG00000112033; HGNC ID: 9235
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa03320PPAR signaling pathway
hsa04310Wnt signaling pathway
hsa05221Acute myeloid leukemia
hsa05200Pathways in cancer
Pathway IDPathway Name
Gene Expression
Pathway IDPathway Name
200052Presenilin action in Notch and Wnt signaling
Pathway IDPathway Name
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
aerobic fitness insulin
NORMALVARIATION
atherosclerosis, coronary
colorectal cancer
CARDIOVASCULAR
height
Growth Disorders
PHARMACOGENOMIC
body mass
response to antipsychotic treatment
metabolic syndrome
cardiorespiratory fitness cholesterol, HDL
glucose insulin
METABOLIC
obesity
body mass cholesterol, LDL glucose insulin
atherosclerosis, coronary body mass cholesterol, HDL cholesterol, LDL cholesterol, VLDL
coronary heart disease
Desease Name
Response to antipsychotic treatment
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C097240 15-deoxy-delta(12,14)-prostaglandin J2 15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of PPARD proteinincreases expression 17341418
C025984 15-hydroxy-5,8,11,13-eicosatetraenoic acid 15-hydroxy-5,8,11,13-eicosatetraenoic acid binds to and results in increased activity of PPARD proteinaffects binding|increases activity 12069687
C103958 1-hydroxyvitamin D5 1-hydroxyvitamin D5 results in decreased expression of PPARD proteindecreases expression 16051482
C022776 2-bromopalmitate 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]affects binding|increases activity 15997096
C040668 2-ethylhexanoic acid 2-ethylhexanoic acid affects the expression of PPARD mRNAaffects expression 15647598
C040668 2-ethylhexanoic acid 2-ethylhexanoic acid affects the expression of PPARD proteinaffects expression 15647598
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased activity of PPARD proteinincreases activity 17185614
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid PPARD protein promotes the reaction [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased phosphorylation of AKT1 protein]increases phosphorylation|increases reaction 19906781
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid PPARD protein promotes the reaction [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased phosphorylation of NOS3 protein]increases phosphorylation|increases reaction 19906781
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid binds to PPARD proteinaffects binding 17726147
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid promotes the reaction [PPARD protein binds to RELA protein]affects binding|increases reaction 15721863
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased activity of PPARD proteinincreases activity 15721863
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased activity of PPARD protein] which results in decreased susceptibility to Phenylephrinedecreases response to substance|increases activity 15721863
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of PPARD mRNAincreases expression 12512042
C520164 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid 4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid binds to and results in increased activity of PPARD proteinaffects binding|increases activity 17437057
C090942 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [TNF protein results in increased expression of and results in increased phosphorylation of PPARD protein]decreases reaction|increases expression|increases phosphorylation 12512042
C047628 8-hydroxyeicosatetraenoic acid 8-hydroxyeicosatetraenoic acid binds to and results in increased activity of PPARD proteinaffects binding|increases activity 12069687
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PPARD mRNAaffects expression 16483693
C432165 anthra(1,9-cd)pyrazol-6(2H)-one anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Indomethacin results in increased expression of PPARD protein]decreases reaction|increases expression 17341418
C061374 antimonite antimonite results in increased expression of PPARD mRNAincreases expression 17400267
C061374 antimonite tyrphostin AG 1478 inhibits the reaction [antimonite results in increased expression of PPARD mRNA]decreases reaction|increases expression 17400267
C015001 arsenite arsenite results in increased expression of PPARD mRNAincreases expression 17400267
C015001 arsenite tyrphostin AG 1478 inhibits the reaction [arsenite results in increased expression of PPARD mRNA]decreases reaction|increases expression 17400267
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of PPARD mRNAaffects expression 17331233
D001241 Aspirin Aspirin results in decreased expression of PPARD proteindecreases expression 18678619
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PPARD mRNAaffects cotreatment|increases expression 18164116
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PPARD mRNAdecreases expression 20064835
D001629 Bezafibrate Bezafibrate binds to and results in increased activity of PPARD proteinaffects binding|increases activity 16193754
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of PPARD mRNAincreases expression 15336504
D002211 Capsaicin Capsaicin results in decreased expression of PPARD mRNAdecreases expression 18769453
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of BAX mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of BCL2A1A mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of BCL2A1B mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of BCL2A1C mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of BCL2L1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of BDKRB1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CCND1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CCR5 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CD14 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CD74 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CSF3 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CXCR5 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of CYP2B10 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of ELF3 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of F3 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of FN1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of GADD45B mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of HMOX1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of ICAM1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of IL1RN mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of IRF2BP2 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of MMP12 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of MMP9 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of NFKB1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of PDGFRB mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of RELA protein]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of S100A6 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TAP1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TNC mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TNFRSF12A mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TNFRSF12A protein]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of TNIP1 mRNA]affects reaction|increases expression 18038451
D002251 Carbon Tetrachloride PPARD protein affects the reaction [Carbon Tetrachloride results in increased expression of VIM mRNA]affects reaction|increases expression 18038451
D003474 Curcumin Curcumin results in decreased expression of PPARD mRNAdecreases expression 19294764
D003474 Curcumin Curcumin results in decreased expression of PPARD proteindecreases expression 19294764
D016572 Cyclosporine Cyclosporine results in increased expression of PPARD mRNAincreases expression 20106945
D003907 Dexamethasone Dexamethasone results in increased expression of PPARD mRNAincreases expression 19022236
D004041 Dietary Fats Dietary Fats results in decreased expression of PPARD mRNAdecreases expression 18457598
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in increased expression of PPARD proteinincreases expression 16455614
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate affects the expression of PPARD mRNAaffects expression 15647598
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate affects the expression of PPARD proteinaffects expression 15647598
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PPARD mRNAaffects cotreatment|increases expression 18164116
D002117 Calcitriol Calcitriol results in increased expression of PPARD mRNAincreases expression 15890193
D004281 Docosahexaenoic Acids PPARD protein promotes the reaction [Docosahexaenoic Acids results in increased expression of LPIN2 mRNA]increases expression|increases reaction 19805517
D004281 Docosahexaenoic Acids PPARD protein promotes the reaction [Docosahexaenoic Acids results in increased expression of ST3GAL5 mRNA]increases expression|increases reaction 19805517
D004317 Doxorubicin Doxorubicin results in decreased expression of PPARD mRNAdecreases expression 16404146
D004610 Ellagic Acid Ellagic Acid results in decreased expression of PPARD mRNAdecreases expression 12002526
C504648 ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate results in increased activity of [RXRA protein binds to PPARD protein]affects binding|increases activity 15997096
D005230 Fatty Acids, Nonesterified Fatty Acids, Nonesterified promotes the reaction [PPARD protein binds to LPIN2 enhancer]affects binding|increases reaction 19805517
D005230 Fatty Acids, Nonesterified Fatty Acids, Nonesterified promotes the reaction [PPARD protein binds to ST3GAL5 enhancer]affects binding|increases reaction 19805517
D006118 Griseofulvin Griseofulvin results in increased expression of PPARD mRNAincreases expression 9548566
C529769 GSK0660 GSK0660 binds to and results in decreased activity of PPARD proteinaffects binding|decreases activity 19906781
C479979 GW0742 GW0742 binds to and results in increased activity of PPARD proteinaffects binding|increases activity 16326050
18393431
C479979 GW0742 monobutyl phthalate inhibits the reaction [GW0742 binds to and results in increased activity of PPARD protein]affects binding|decreases reaction|increases activity 16326050
C479979 GW0742 norathyriol inhibits the reaction [GW0742 results in increased activity of PPARD protein]decreases reaction|increases activity 18393431
C479979 GW0742 PPARD protein promotes the reaction [GW0742 results in increased phosphorylation of AKT1 protein]increases phosphorylation|increases reaction 19906781
C479979 GW0742 PPARD protein promotes the reaction [GW0742 results in increased phosphorylation of NOS3 protein]increases phosphorylation|increases reaction 19906781
C479979 GW0742 Quercetin inhibits the reaction [GW0742 results in increased activity of PPARD protein]decreases reaction|increases activity 18393431
C479979 GW0742 GW0742 binds to and results in increased activity of PPARD proteinaffects binding|increases activity 18593727
19577614
C479979 GW0742 PPARD protein promotes the reaction [GW0742 results in increased expression of SLC25A20 mRNA]increases expression|increases reaction 19577614
C425931 GW 501516 GW 501516 binds to and results in increased activity of PPARD proteinaffects binding|increases activity 18292206
C425931 GW 501516 [GW 501516 co-treated with PPARD protein] results in increased expression of PPARGC1A mRNAaffects cotreatment|increases expression 17275789
C425931 GW 501516 GW 501516 binds to PPARD proteinaffects binding 18701451
C425931 GW 501516 [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased activity of RELA protein]affects binding|decreases reaction|increases activity 18701451
C425931 GW 501516 [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]affects binding|decreases reaction|increases expression 18701451
C425931 GW 501516 [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]affects binding|decreases reaction|increases expression 18701451
C425931 GW 501516 GW 501516 binds to and results in increased activity of PPARD proteinaffects binding|increases activity 17341418
D019377 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid binds to and results in increased activity of PPARD proteinaffects binding|increases activity 12069687
D007213 Indomethacin anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Indomethacin results in increased expression of PPARD protein]decreases reaction|increases expression 17341418
D007213 Indomethacin Indomethacin results in decreased activity of PPARD proteindecreases activity 10555149
D007213 Indomethacin Indomethacin results in decreased expression of PPARD proteindecreases expression 18678619
D007213 Indomethacin Indomethacin results in increased expression of PPARD proteinincreases expression 17341418
D007213 Indomethacin PPARD protein affects the reaction [Indomethacin results in decreased expression of YWHAE protein]affects reaction|decreases expression 17409426
D007213 Indomethacin SB 203580 inhibits the reaction [Indomethacin results in increased expression of PPARD protein]decreases reaction|increases expression 17341418
D008070 Lipopolysaccharides Lipopolysaccharides promotes the reaction [RELA protein binds to PPARD protein]affects binding|increases reaction 15728586
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate affects the expression of PPARD mRNAaffects expression 15647598
C016599 mono-(2-ethylhexyl)phthalate mono-(2-ethylhexyl)phthalate affects the expression of PPARD proteinaffects expression 15647598
C028577 monobutyl phthalate monobutyl phthalate inhibits the reaction [GW0742 binds to and results in increased activity of PPARD protein]affects binding|decreases reaction|increases activity 16326050
C069053 norathyriol norathyriol inhibits the reaction [GW0742 results in increased activity of PPARD protein]decreases reaction|increases activity 18393431
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in increased activity of PPARD proteinincreases activity 17047030
C023036 perfluorooctanoic acid perfluorooctanoic acid results in increased activity of PPARD proteinincreases activity 17047030
D010656 Phenylephrine [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased activity of PPARD protein] which results in decreased susceptibility to Phenylephrinedecreases response to substance|increases activity 15721863
D010656 Phenylephrine [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased activity of RELA protein]affects binding|decreases reaction|increases activity 18701451
D010656 Phenylephrine [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]affects binding|decreases reaction|increases expression 18701451
D010656 Phenylephrine [GW 501516 binds to PPARD protein] inhibits the reaction [Phenylephrine results in increased expression of NPPB mRNA]affects binding|decreases reaction|increases expression 18701451
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PPARD mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid promotes the reaction [PPARD protein binds to NFKBIA promoter]affects binding|increases reaction 19438714
C006253 pirinixic acid [pirinixic acid results in increased activity of PPARD protein] which results in increased expression of NFKBIA mRNAincreases activity|increases expression 19438714
D011794 Quercetin Quercetin inhibits the reaction [GW0742 results in increased activity of PPARD protein]decreases reaction|increases activity 18393431
C059514 resveratrol resveratrol results in decreased expression of PPARD mRNAdecreases expression 12002526
12569576
C093642 SB 203580 SB 203580 inhibits the reaction [Indomethacin results in increased expression of PPARD protein]decreases reaction|increases expression 17341418
D013467 Sulindac PPARD protein affects the susceptibility to Sulindacaffects response to substance 10866668
C025462 sulindac sulfide PPARD protein affects the reaction [sulindac sulfide results in decreased expression of YWHAE protein]affects reaction|decreases expression 17409426
C025462 sulindac sulfide PPARD protein inhibits the reaction [sulindac sulfide results in increased expression of CDKN1A mRNA]decreases reaction|increases expression 16091736
C025462 sulindac sulfide sulindac sulfide binds to and results in decreased activity of PPARD proteinaffects binding|decreases activity 16091736
C025462 sulindac sulfide sulindac sulfide results in decreased activity of PPARD proteindecreases activity 10555149
C025462 sulindac sulfide sulindac sulfide results in decreased expression of PPARD mRNAdecreases expression 17409426
18678619
C025462 sulindac sulfide sulindac sulfide results in decreased expression of PPARD proteindecreases expression 18678619
17409426
C025462 sulindac sulfide sulindac sulfide results in increased expression of PPARD mRNAincreases expression 11948457
C025463 sulindac sulfone sulindac sulfone results in increased expression of PPARD mRNAincreases expression 11948457
D013755 Tetradecanoylphorbol Acetate PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA]affects reaction|increases expression 10866668
D013755 Tetradecanoylphorbol Acetate PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA]affects reaction|increases expression 10866668
D013755 Tetradecanoylphorbol Acetate PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA]affects reaction|increases expression 10866668
D013755 Tetradecanoylphorbol Acetate PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PCNA mRNA]affects reaction|increases expression 10866668
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased expression of PPARD mRNAincreases expression 10866668
C410666 tetradecylselenoacetic acid tetradecylselenoacetic acid results in increased activity of PPARD proteinincreases activity 17185614
C101044 tyrphostin AG 1478 tyrphostin AG 1478 inhibits the reaction [antimonite results in increased expression of PPARD mRNA]decreases reaction|increases expression 17400267
C101044 tyrphostin AG 1478 tyrphostin AG 1478 inhibits the reaction [arsenite results in increased expression of PPARD mRNA]decreases reaction|increases expression 17400267
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 4.9114745880
MESH:D000014 Abnormalities, Drug-Induced Capsaicin 7.4418926900
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 7.446734493
MESH:D000138 Acidosis Ammonium Chloride 2.9918287403
MESH:D058186 Acute Kidney Injury Capsaicin 11.6918460982
MESH:D058186 Acute Kidney Injury resveratrol 11.6916538975
MESH:D058186 Acute Kidney Injury Sulindac 11.697897758
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.2811850527 18653653
MESH:D055371 Acute Lung Injury pirinixic acid 7.2818653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 8.7320127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 8.7317418594
MESH:D000230 Adenocarcinoma Indomethacin 8.7316537180
MESH:D000230 Adenocarcinoma Sulindac 8.7311910360
MESH:D000236 Adenoma Benzo(a)pyrene 21.626695378
MESH:D000236 Adenoma beta-Naphthoflavone 21.6219389873
MESH:D000236 Adenoma Diethylnitrosamine 21.626695378 10737359
MESH:D000236 Adenoma Indomethacin 21.6211497255
MESH:D000236 Adenoma resveratrol 21.6215688382
MESH:D000236 Adenoma Sulindac 21.6210223192
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 8.1918056438 17162532 19052882 19061943 17620307 16434500
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.1916434500
MESH:D011125 Adenomatous Polyposis Coli Sulindac 8.7311535846 17611924 11874996 16460482 19003578 12394442 15623613
MESH:D011125 Adenomatous Polyposis Coli sulindac sulfone 8.7316150858
MESH:D000419 Albuminuria Doxorubicin 4.0021441931
MESH:D019973 Alcohol-Related Disorders Curcumin 4.5017887948
MESH:D000505 Alopecia Capsaicin 4.2717569567
MESH:D016301 Alveolar Bone Loss Indomethacin 4.7817225004
MESH:D000544 Alzheimer Disease Curcumin 8.1115590663
MESH:D000544 Alzheimer Disease Indomethacin 8.1115579461 17627676
MESH:D000544 Alzheimer Disease resveratrol 8.1116183991 16162502
MESH:D000544 Alzheimer Disease sulindac sulfide 8.1118759972
MESH:D000743 Anemia, Hemolytic Quercetin 3.7217084956
MESH:D001014 Aortic Aneurysm Indomethacin 4.3010231640
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 9.8519183758
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 9.8510388637
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.6117460149
MESH:D001161 Arteriosclerosis Dietary Fats 3.3315238619
MESH:D018771 Arthralgia Indomethacin 4.582160914
MESH:D001169 Arthritis, Experimental Dexamethasone 6.4317659584
MESH:D001169 Arthritis, Experimental resveratrol 6.4317115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.3616807698
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.3611248219
MESH:D055963 Asthma, Aspirin-Induced Aspirin 4.2212372130 20485159
MESH:D001260 Ataxia Telangiectasia Quercetin 4.4015336622
MESH:D050197 Atherosclerosis Curcumin 5.7118704882
MESH:D050197 Atherosclerosis resveratrol 5.7116873680 17967414
MESH:D001321 Autistic Disorder Docosahexaenoic Acids 3.2818582451
MESH:D001327 Autoimmune Diseases Curcumin 9.0019761891
MESH:D001327 Autoimmune Diseases Quercetin 9.0019761891
MESH:D001477 Bartter Syndrome Indomethacin 4.4210684365
MESH:D001778 Blood Coagulation Disorders pirinixic acid 2.6319483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.1114601052
MESH:D001913 Bowen's Disease Sulindac 4.7711207687
MESH:D001919 Bradycardia Capsaicin 9.0018207255
MESH:D001919 Bradycardia Phenylephrine 9.0015306635
MESH:D001929 Brain Edema Indomethacin 4.4411481608
MESH:D002545 Brain Ischemia Capsaicin 19.5919211983
MESH:D002545 Brain Ischemia Curcumin 19.5916770732
MESH:D002545 Brain Ischemia Indomethacin 19.5912524144
MESH:D002545 Brain Ischemia resveratrol 19.5917600658
MESH:D001932 Brain Neoplasms Aspirin 11.9115481559
MESH:D001932 Brain Neoplasms Curcumin 11.9117596214
MESH:D001932 Brain Neoplasms Doxorubicin 11.9117150277
MESH:D001943 Breast Neoplasms Aspirin 7.3015161893
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 7.3017474063 20146248
MESH:D001943 Breast Neoplasms Calcitriol 7.3011237771
MESH:D001943 Breast Neoplasms Curcumin 7.3016243823 19250217 18462866 18593918
MESH:D001943 Breast Neoplasms Dietary Fats 7.3020435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 7.3017474063
MESH:D001943 Breast Neoplasms Doxorubicin 7.3016935488 16595493 15994142 15136595 16115903 16322301 18382427 15634643 17426702 15939500 17369602 16826403 15567936 15993339 15668708 16096432 18234424 18695136 11325840 15692762 18628466 16264153 17983394 19526202
MESH:D001943 Breast Neoplasms Indomethacin 7.3017401462
MESH:D001943 Breast Neoplasms Quercetin 7.3018628248
MESH:D001943 Breast Neoplasms resveratrol 7.3017651959 16393696 17534123
MESH:D001943 Breast Neoplasms Sulindac 7.3016642371
MESH:D016535 Bronchial Hyperreactivity tyrphostin AG 1478 4.4312794006
MESH:D002056 Burns Indomethacin 4.1410459503
MESH:D002100 Cachexia Indomethacin 4.4315625704 16537180 11239499 15141370
MESH:D002105 Cadmium Poisoning Quercetin 4.9616962696
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.2216097048 15721981 16124888 10355542 18705752 15673190 16011737 15700767 16192424 3786805 16050911 16227642
MESH:D002276 Carcinoid Tumor Doxorubicin 4.2216051944
MESH:D002277 Carcinoma Curcumin 3.3818593918
MESH:D006528 Carcinoma, Hepatocellular anthra(1,9-cd)pyrazol-6(2H)-one 12.1619418558
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 12.1618788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 12.1620214788 20524982 18494052 19171122 10737359 19701751 16540662 20935162 16328049 11831363 19383236 17428255 19107877 18506893 16830150 19052882 20007298 3084413 17162532 17761372 20101231 18788625 16681979 19519916 18691550 18785209 20727157 19394651 18056438 19919837 16698587 18393292 20432363 17055752 18978308 16807293 16502159 16878318 3581430 20514400 19335982 19539802 16779866 17138121 21159647 18210153 16569478 17978847 18971187 16288022 19822196 20084675 19418558 10672840 16935385 17173139 20512989 19208518 18665156
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 12.1617876044 16234567 18059187 16023760
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 12.1616391822
MESH:D006528 Carcinoma, Hepatocellular Quercetin 12.1619519916 12508355
MESH:D006528 Carcinoma, Hepatocellular resveratrol 12.1619321006 16227395
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 9.5211053908
MESH:D018827 Carcinoma, Lewis Lung resveratrol 9.5216675471
MESH:D018276 Carcinoma, Medullary Indomethacin 4.7818791128 11352223 14736730
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 7.8818414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfide 7.8812391285
MESH:D002289 Carcinoma, Non-Small-Cell Lung sulindac sulfone 7.8818758305
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.3917234771
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 5.801485588 16201981
MESH:D002292 Carcinoma, Renal Cell Indomethacin 5.8017341418
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 18.8120419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 18.8111237771
MESH:D002294 Carcinoma, Squamous Cell Curcumin 18.8118462866
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 18.816189445
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 18.8115482327 12636206
MESH:D002294 Carcinoma, Squamous Cell resveratrol 18.8116227395
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 18.8118922899
MESH:D006332 Cardiomegaly Phenylephrine 6.0817287366 15728586 11754973 17124262 16170337 11179087
MESH:D006332 Cardiomegaly Quercetin 6.0819794523
MESH:D009202 Cardiomyopathies Doxorubicin 3.1417924179 16269455 17974986 16651473 17007740 17351982 16455267 17131338 17382496 16952015 16242529 16731534 17329180 15811867 15476868 17928571 17308081 16364871 16612575 16109756 15792986 16278810 17519947 15505089 18627295
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7216243910 17334414
MESH:D002318 Cardiovascular Diseases resveratrol 3.0715458977
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 5.2512371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 5.257505956 2727394 17174075 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.2019052882
MESH:D002764 Cholecystitis Indomethacin 4.5811181007
MESH:D002779 Cholestasis Cyclosporine 6.3119486331
MESH:D002779 Cholestasis pirinixic acid 6.3119176532
MESH:D003092 Colitis Curcumin 7.9418200517 16804969 16782535
MESH:D003092 Colitis resveratrol 7.9416474422
MESH:D003103 Coloboma Curcumin 4.0318809619
MESH:D003110 Colonic Neoplasms arsenite 18.0515037631
MESH:D003110 Colonic Neoplasms Aspirin 18.0512411196
MESH:D003110 Colonic Neoplasms Curcumin 18.0519359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 18.0515824018
MESH:D003110 Colonic Neoplasms Indomethacin 18.0515637740 15625704 15936596 15786552 11260862 15963497
MESH:D003110 Colonic Neoplasms Quercetin 18.0516640504 15741050 19056647 11134977 17191121 19440933 17148506
MESH:D003110 Colonic Neoplasms resveratrol 18.0516338953
MESH:D003110 Colonic Neoplasms Sulindac 18.0512458338 12902858
MESH:D015179 Colorectal Neoplasms Aspirin 9.2717047198
MESH:D015179 Colorectal Neoplasms Doxorubicin 9.2718802399 18259882
MESH:D015179 Colorectal Neoplasms Indomethacin 9.2718059344 12606626 17054584 11197048
MESH:D015179 Colorectal Neoplasms Quercetin 9.2718095365 18852136
MESH:D015179 Colorectal Neoplasms resveratrol 9.2716550006
MESH:D015179 Colorectal Neoplasms Sulindac 9.2711197048 10666051 11076880 18059344
MESH:D015179 Colorectal Neoplasms sulindac sulfone 9.2710416599 11197048 10666051 18059344
MESH:D016510 Corneal Neovascularization Curcumin 4.3318497527
MESH:D003327 Coronary Disease resveratrol 3.3616507316
MESH:D018352 Coronavirus Infections Indomethacin 5.1317302372
MESH:D003371 Cough Capsaicin 4.5910350223
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.2617728286
MESH:D003550 Cystic Fibrosis Docosahexaenoic Acids 4.1819747007
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.8812438553
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 5.9816882537
MESH:D003876 Dermatitis, Atopic pirinixic acid 5.9818249437
MESH:D003920 Diabetes Mellitus ethyl(E,E,E)-7-(2-n-propoxy-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-naphthalen-3-yl)-6-fluorp-3-methylocta-2,4,6-trienoate 5.5915997096
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 6.9919496084
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 6.9916873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.0118403477
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0120387270
MESH:D003928 Diabetic Nephropathies Curcumin 7.6218204486
MESH:D003928 Diabetic Nephropathies resveratrol 7.6216286809
MESH:D003930 Diabetic Retinopathy Sulindac 4.6312861449 17621415
MESH:D003967 Diarrhea Dexamethasone 6.487237001
MESH:D003967 Diarrhea Indomethacin 6.487237001 7907874
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 5.117120509 21278145 6623471 7179309 15998439 11566570 15968718 6884620 19085960 19336974 4309450 2869522 16177239 10092053 3732212 15027814 3786805 17522070 10915739 16227642 9327722 7440962
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.1119107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 5.1117416283
MESH:D004362 Drug Toxicity Doxorubicin 3.2418602426
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 4.5718446180 16326151 18043480 12774134 17190690 16133044
MESH:D004381 Duodenal Ulcer Capsaicin 12.3610671773 11535926
MESH:D004381 Duodenal Ulcer Curcumin 12.3617351913
MESH:D004381 Duodenal Ulcer Indomethacin 12.3617202747 16699067 17045617 11595415 11595431 17329845 10671773 17151854 11535926 11991626 17351913
MESH:D050171 Dyslipidemias Dietary Fats 3.0318367378
MESH:D004485 Eczema Dexamethasone 3.9112438553
MESH:D004487 Edema Aspirin 24.8117259670
MESH:D004487 Edema Dexamethasone 24.8119703484
MESH:D004487 Edema Indomethacin 24.817990266 16100529 10653021 8985016 8273558 7907874 19703484
MESH:D004487 Edema perfluorooctanoic acid 24.8117259670 12083418
MESH:D004487 Edema pirinixic acid 24.8112083418
MESH:D004487 Edema resveratrol 24.818985016
MESH:D004487 Edema Tetradecanoylphorbol Acetate 24.8111698051 8273558 9599246 16716910 15177302 7812673 8113982
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental 15-deoxy-delta(12,14)-prostaglandin J2 12.5116844232
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 12.5115138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 12.5117872969
MESH:D016889 Endometrial Neoplasms Doxorubicin 3.0617359293
MESH:D004715 Endometriosis Indomethacin 7.9415652904
MESH:D004715 Endometriosis Sulindac 7.9415652904
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.5718037988
MESH:D019446 Endotoxemia Indomethacin 8.7518509659
MESH:D019446 Endotoxemia Lipopolysaccharides 8.7515821434 17637181 15328337
MESH:D004751 Enteritis Indomethacin 4.1616328016 10567023 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 10.5117980183
MESH:D020345 Enterocolitis, Necrotizing resveratrol 10.5117923197
MESH:D004802 Eosinophilia Indomethacin 3.5011298111
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.5316302075
MESH:D004935 Esophageal Diseases Capsaicin 5.1319566590
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 6.3316530937
MESH:D004938 Esophageal Neoplasms Indomethacin 6.3311005569
MESH:D004938 Esophageal Neoplasms Sulindac 6.3312235107
MESH:D005234 Fatty Liver arsenite 29.1118296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 29.1117595544 16239168 15959796 12631006 12795759 19224547 61145 16045604
MESH:D005234 Fatty Liver Curcumin 29.1119297423
MESH:D005234 Fatty Liver Cyclosporine 29.1119224547
MESH:D005234 Fatty Liver Dietary Fats 29.1118296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 29.1121071580 20387270
MESH:D005234 Fatty Liver pirinixic acid 29.1119236843 20131406
MESH:D005334 Fever Indomethacin 7.6917627676 11852909 10431976
MESH:D005334 Fever Lipopolysaccharides 7.6911852909 9205823
MESH:D018221 Fibromatosis, Abdominal Sulindac 4.9014745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 9.8819069698
MESH:D018222 Fibromatosis, Aggressive Sulindac 9.8819069698
MESH:D005354 Fibrosarcoma Indomethacin 4.3210962813
MESH:D005355 Fibrosis arsenite 32.9318296743
MESH:D005355 Fibrosis Carbon Tetrachloride 32.9318705752
MESH:D005355 Fibrosis Curcumin 32.9318705752
MESH:D005355 Fibrosis Cyclosporine 32.9312168785 12639820
MESH:D005355 Fibrosis Dietary Fats 32.9318296743
MESH:D005355 Fibrosis Indomethacin 32.9317994277
MESH:D005355 Fibrosis Quercetin 32.9319474275
MESH:D005499 Folliculitis Indomethacin 4.5811298111
MESH:D005756 Gastritis Indomethacin 4.1615046732
MESH:D005764 Gastroesophageal Reflux Sulindac 4.4611910360
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.1318462866
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.648708960
MESH:D005909 Glioblastoma Aspirin 27.4412870263
MESH:D005909 Glioblastoma Capsaicin 27.4418405923
MESH:D005909 Glioblastoma Curcumin 27.4417596214
MESH:D005909 Glioblastoma Doxorubicin 27.4417150277
MESH:D005909 Glioblastoma Indomethacin 27.4412870263
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 27.4417162496
MESH:D005909 Glioblastoma Quercetin 27.4419804834
MESH:D005910 Glioma Indomethacin 5.4418371953 16487511
MESH:D005910 Glioma Quercetin 5.4417643826
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 3.8211849393
MESH:D006073 Gout Indomethacin 4.7811248219
MESH:D006261 Headache Aspirin 4.3815240983
MESH:D006258 Head and Neck Neoplasms Curcumin 10.7418829502 18462866
MESH:D006258 Head and Neck Neoplasms Doxorubicin 10.7415692506
MESH:D006258 Head and Neck Neoplasms Indomethacin 10.7415482327
MESH:D006356 Heartburn Capsaicin 5.1319566590
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.3320471113
MESH:D006331 Heart Diseases Doxorubicin 3.0816495754 16330681 17875725 16707910 18006777 16244371 14766674 12587719 16244372 17888722 16144979 16879835 18674790
MESH:D006333 Heart Failure Doxorubicin 5.8017481944
MESH:D006333 Heart Failure pirinixic acid 5.8020558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.3915692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.8515720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.8816366002
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.0515633222
MESH:D006505 Hepatitis Carbon Tetrachloride 3.0519110552 19900420
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.1415135802
MESH:D006529 Hepatomegaly GW0742 11.6318593727
MESH:D006529 Hepatomegaly perfluorooctanoic acid 11.633609246
MESH:D006529 Hepatomegaly pirinixic acid 11.6316221962 18467677 19772884 19176532
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.4817701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.847520565
MESH:D006561 Herpes Simplex resveratrol 3.6116876885
MESH:D006689 Hodgkin Disease Doxorubicin 2.9415147373 18501091 17606976
MESH:D012001 Hyperacusis Aspirin 5.1815240983
MESH:D006930 Hyperalgesia Capsaicin 10.7317434803 17043245
MESH:D006930 Hyperalgesia Indomethacin 10.7312727271
MESH:D006930 Hyperalgesia perfluorooctanoic acid 10.7312083418
MESH:D034321 Hyperamylasemia Indomethacin 5.1317883296
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 3.9616899240
MESH:D006937 Hypercholesterolemia Curcumin 12.3918704882
MESH:D006937 Hypercholesterolemia Dietary Fats 12.3921332399
MESH:D006937 Hypercholesterolemia resveratrol 12.3917188708
MESH:D006940 Hyperemia Indomethacin 4.4312524144
MESH:D006943 Hyperglycemia pirinixic acid 7.5820558911
MESH:D006943 Hyperglycemia Quercetin 7.5818262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 12.4521332399
MESH:D006949 Hyperlipidemias Indomethacin 12.4517546600
MESH:D006949 Hyperlipidemias resveratrol 12.4516873680
MESH:D006973 Hypertension Cyclosporine 10.3310903974
MESH:D006973 Hypertension Dexamethasone 10.3317042910
MESH:D006973 Hypertension Phenylephrine 10.338949925 12717712
MESH:D006973 Hypertension Quercetin 10.3318356687
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.5315338365
MESH:D006984 Hypertrophy Phenylephrine 4.0418502941 12791704
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.8017488730
MESH:D007077 Ileal Diseases Indomethacin 4.4418306037 10574470
MESH:D007079 Ileitis Indomethacin 4.7810651667 10647630 16133968
MESH:D007235 Infant, Premature, Diseases Indomethacin 4.7816133044
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.0917600658
MESH:D007249 Inflammation Capsaicin 34.6316956363
MESH:D007249 Inflammation Curcumin 34.6316956363 17151092 18403477
MESH:D007249 Inflammation Dexamethasone 34.6311099482 8960868
MESH:D007249 Inflammation Dietary Fats 34.6320412841
MESH:D007249 Inflammation Diethylnitrosamine 34.6318785209
MESH:D007249 Inflammation Indomethacin 34.633291741 7812673 12568917
MESH:D007249 Inflammation Lipopolysaccharides 34.6317237260 12878042 17255318 9205823 17963957
MESH:D007249 Inflammation perfluorooctanoic acid 34.6312083418
MESH:D007249 Inflammation resveratrol 34.6316366677
MESH:D007249 Inflammation Sulindac 34.633291741
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 34.637562506 15177302 11698051 7812673 8273558
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.9518200517 18596194
MESH:D007251 Influenza, Human Quercetin 9.2516624496
MESH:D007251 Influenza, Human resveratrol 9.2516624496
MESH:D007333 Insulin Resistance Dietary Fats 5.9411836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 5.9416306350
MESH:D007410 Intestinal Diseases Indomethacin 3.7711686837 11713966 11855677 15610444 15831440 17329856 17994277 10210152 18236018
MESH:D007414 Intestinal Neoplasms Curcumin 8.4510783313
MESH:D007414 Intestinal Neoplasms Sulindac 8.4510213222 12584176 10223192 12663524 12628509 12351151
MESH:D007417 Intestinal Polyps Sulindac 4.4611245490 12394442
MESH:D019586 Intracranial Hypertension Indomethacin 4.7815241188
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.1017255318
MESH:D007579 Jejunal Diseases Indomethacin 4.4416133968 10574470 18306037
MESH:D007627 Keloid Quercetin 4.3917086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.8515604871
MESH:D007674 Kidney Diseases Cyclosporine 11.5718776723 8314463 10903974
MESH:D007674 Kidney Diseases Doxorubicin 11.5715699352 15369732 16775033
MESH:D007674 Kidney Diseases Indomethacin 11.5717190690
MESH:D007674 Kidney Diseases Quercetin 11.5716962696
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.6416707910
MESH:D007680 Kidney Neoplasms Cyclosporine 2.2812371664
MESH:D007889 Leiomyoma Curcumin 4.0418555241
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.4410320625 12228301 11703811
MESH:D007938 Leukemia Curcumin 5.5818462866
MESH:D007938 Leukemia Quercetin 5.5817468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.5716085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.4916106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Docosahexaenoic Acids 8.4917077332
MESH:D007948 Leukemia, Monocytic, Acute anthra(1,9-cd)pyrazol-6(2H)-one 4.8016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.4916572323 15631656 10785260
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.5218360721
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.1916087638
MESH:D015458 Leukemia, T-Cell Curcumin 4.2116106398
MESH:D007964 Leukocytosis Indomethacin 4.7816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.1317980183
MESH:D007970 Leukopenia Lipopolysaccharides 4.1215821434
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 4.658812269
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.1311479899
MESH:D008103 Liver Cirrhosis arsenite 12.9518296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 12.9511903743 16239168 17157831 16943688 17174718 11408273 17334410 21278145 16221502
MESH:D008103 Liver Cirrhosis Dietary Fats 12.9518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 12.9520032147 19638242 18665156 18407596 18522880
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 3.8412468960
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 11.4815730626 17631135 12546737 12632512 12389079 12667390 18210741 17525996 12445418 17761835 16116963 14716833 18376398 17900296 12649538 13678700 12632514 16097048 17922224 18205269 17557913 18166357 15338365 17721639 18412020 17708605 18251166 18481824 18472094 12741479 15893842 17714472 18054572 10355542 17805973 15818738 17823541 15362042 15650968 18187930 12666154 15052691 15370692 15123356 18395914 18156304 16015684 12609069 15959796 18429990 16011737 15996030 18006644 18395095 14716496 18420326 17976157 12958196 17565644 20821823 15925388 12586293 14748882 16027843 18277467 16192424 15931870 17766677 15673190 18705752 16248980 15057751 18317297 18279442 12898905 18339082 17481882 11481614 18263696 17640975 14620537 12445421 17698563 16033810 14512876 17944888 16136751 14724832 18472332 15876570 16638106 18418968 17869086
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 11.4818705752 18006644 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 11.4816718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 11.4816439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 11.4818194892
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 11.4812878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 11.4815474484
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 11.4812741479
MESH:D008107 Liver Diseases Capsaicin 13.4216956363
MESH:D008107 Liver Diseases Carbon Tetrachloride 13.4216246199 16964402 15720792 17285989 15830285
MESH:D008107 Liver Diseases Curcumin 13.4216956363
MESH:D008107 Liver Diseases Diethylnitrosamine 13.4217034775
MESH:D008107 Liver Diseases Docosahexaenoic Acids 13.4217056761
MESH:D008107 Liver Diseases Sulindac 13.4216867024 14986274
MESH:D017093 Liver Failure Carbon Tetrachloride 3.6015123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.1914706259 16899240
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 25.0420195826 21137059
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 25.0419389873 21295105
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 25.0419294768
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 25.0411940454
MESH:D008113 Liver Neoplasms Diethylnitrosamine 25.0419850985 18754104 18978307 9163691 20118626 18644402 19642983 19690152 20583210 19426721 19073162 19638242 18648771 20137499 16942905 19812893 20501860 10737359 20101389 20452335 21047994 12112319 19254457 20492335 15885732 20405173 21167192 19256749 19996281 21278145 18977376 12771043 19427195 19499222 19090486 15175105 19833225 2422723 2862719 19551842 21071580 19255062 20434301 19294768
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 25.0418709148 14757943
MESH:D008113 Liver Neoplasms pirinixic acid 25.0420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Quercetin 25.0418980244
MESH:D008113 Liver Neoplasms resveratrol 25.0419812893 19073162 20405173 19321006
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 14.6518164116
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.6512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 14.6516842330 18544905 21159647 18079962 17174075 17942915 18308698 16267830 3124819 19009564 19519916 19539802 18253720 18775883 18164116 18093689 18282651 9362446 19004024 2563599 17854601 19126423
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 14.6517085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Quercetin 14.6519519916
MESH:D055370 Lung Injury Asbestos, Crocidolite 7.4517365036
MESH:D055370 Lung Injury Lipopolysaccharides 7.4521114838
MESH:D008175 Lung Neoplasms arsenite 15.7316809336
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 15.7318816296 6695378 18569708 18520028 20464547 20869020 20064080 17053015 20135361
MESH:D008175 Lung Neoplasms Curcumin 15.7318462866 19359593 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 15.7311195469 15824018
MESH:D008175 Lung Neoplasms Diethylnitrosamine 15.7321163286 20512841 20970405 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 15.7317418594 6189445
MESH:D008175 Lung Neoplasms Indomethacin 15.7316537180 11497255 11053908
MESH:D008175 Lung Neoplasms Quercetin 15.7316280456
MESH:D008175 Lung Neoplasms Sulindac 15.7315713900 19359593
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 15.7311807781
MESH:D008223 Lymphoma Curcumin 6.3818462866
MESH:D008223 Lymphoma Doxorubicin 6.3816098063
MESH:D016393 Lymphoma, B-Cell resveratrol 3.7717088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.3117654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.3114749477
MESH:D016399 Lymphoma, T-Cell Curcumin 9.7016173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 9.7015621674
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.6815688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 7.9215458769
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 7.928985016 11606380
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 7.928985016
MESH:D008545 Melanoma Curcumin 6.2618462866 17885582
MESH:D008545 Melanoma Doxorubicin 6.2616827129
MESH:D008545 Melanoma resveratrol 6.2617992120
MESH:D008545 Melanoma Sulindac 6.2616642371
MESH:D008569 Memory Disorders Curcumin 3.6117263510
MESH:D008654 Mesothelioma Asbestos, Crocidolite 5.5516166281 16966607 18303189
MESH:D008654 Mesothelioma Doxorubicin 5.5517638057
MESH:D008659 Metabolic Diseases resveratrol 3.8617112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.2016801185
MESH:D008881 Migraine Disorders Aspirin 6.6415240983
MESH:D008881 Migraine Disorders Indomethacin 6.6411903285
MESH:D028361 Mitochondrial Diseases Doxorubicin 3.9815792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 7.1716381670
MESH:D009062 Mouth Neoplasms Indomethacin 7.1712636206
MESH:D052016 Mucositis Doxorubicin 4.2217415656
MESH:D009101 Multiple Myeloma Capsaicin 13.8917505005
MESH:D009101 Multiple Myeloma Curcumin 13.8919372569
MESH:D009101 Multiple Myeloma Dexamethasone 13.8916118317 15867202 15744524
MESH:D009101 Multiple Myeloma resveratrol 13.8916267019 17049120 17164350 17935668 14749477 16490592
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.5017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.5017962980
MESH:D009135 Muscular Diseases Bezafibrate 20.8616239165
MESH:D009135 Muscular Diseases GW0742 20.8618593727
MESH:D009135 Muscular Diseases GW 501516 20.8616239165
MESH:D009135 Muscular Diseases pirinixic acid 20.8616239165
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.199809623
MESH:D009203 Myocardial Infarction Aspirin 14.9812692751
MESH:D009203 Myocardial Infarction Doxorubicin 14.9819429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 14.9819151258
MESH:D009203 Myocardial Infarction Quercetin 14.9819595682
MESH:D009203 Myocardial Infarction resveratrol 14.9816317513 17125593 17015251 16525036 16456233 17188708
MESH:D017202 Myocardial Ischemia resveratrol 3.5517015251 17125593
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 6.9516411023
MESH:D015428 Myocardial Reperfusion Injury Quercetin 6.9519207477
MESH:D009205 Myocarditis resveratrol 4.1817322642
MESH:D009325 Nausea Aspirin 4.6315240983
MESH:D009361 Neoplasm Invasiveness Curcumin 3.8318495463
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.063581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.0618259882
MESH:D009362 Neoplasm Metastasis Indomethacin 8.0611239499 11053908 16537180
MESH:D009369 Neoplasms Benzo(a)pyrene 6.4211141357
MESH:D009369 Neoplasms pirinixic acid 6.4217405874
MESH:D009369 Neoplasms Quercetin 6.4215185748
MESH:D009374 Neoplasms, Experimental Indomethacin 7.5515625704 10663608
MESH:D009374 Neoplasms, Experimental resveratrol 7.558985016
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 3.9512497104
MESH:D009389 Neovascularization, Pathologic arsenite 3.8415738583
MESH:D009401 Nephrosis Doxorubicin 4.2116636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.8517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 7.6719348381 18481113
MESH:D009404 Nephrotic Syndrome Doxorubicin 7.6716889571 15640375
MESH:D009423 Nervous System Neoplasms Curcumin 5.0418462866
MESH:D009447 Neuroblastoma Doxorubicin 2.9415555623
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 16.3020387270
MESH:D019636 Neurodegenerative Diseases Indomethacin 16.3012349958
MESH:D019636 Neurodegenerative Diseases resveratrol 16.3017652729
MESH:D019636 Neurodegenerative Diseases Sulindac 16.3016850258 17266991
MESH:D020078 Neurogenic Inflammation Capsaicin 14.8417961222
MESH:D020078 Neurogenic Inflammation Quercetin 14.8417929310
MESH:D020078 Neurogenic Inflammation resveratrol 14.8417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.5320387270
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 4.399802331
MESH:D009765 Obesity Capsaicin 9.1919056576
MESH:D009765 Obesity Curcumin 9.1919297423
MESH:D009765 Obesity Dietary Fats 9.1917217161 20518802 19632207 20132043 21332399 18674790 16723640 18457598 11836018
MESH:D009765 Obesity pirinixic acid 9.1920558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 4.586374098
MESH:D010003 Osteoarthritis Aspirin 6.787009135
MESH:D010003 Osteoarthritis Indomethacin 6.787009135
MESH:D010024 Osteoporosis Curcumin 3.1018719352
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.4419495926
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.4417513867
MESH:D012516 Osteosarcoma Doxorubicin 3.6515930896
MESH:D010051 Ovarian Neoplasms Curcumin 4.4518462866 19020741
MESH:D010051 Ovarian Neoplasms Quercetin 4.4519005980
MESH:D010146 Pain Aspirin 12.446995502 6363464
MESH:D010146 Pain Capsaicin 12.4419081190 17434803 18987195 17084039 17043245 16996476
MESH:D010146 Pain Indomethacin 12.4417440234 13679232 3291741 17627676
MESH:D010146 Pain Sulindac 12.443291741
MESH:D010149 Pain, Postoperative Indomethacin 4.1018702446 12538197
MESH:D010190 Pancreatic Neoplasms Curcumin 13.7419196508 19401701 17440100
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 13.7416540662
MESH:D010190 Pancreatic Neoplasms Quercetin 13.7416965848
MESH:D010190 Pancreatic Neoplasms Sulindac 13.7416820089 11504793
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 13.7415976015
MESH:D010195 Pancreatitis Fatty Acids, Nonesterified 7.5618983441
MESH:D010195 Pancreatitis Indomethacin 7.5615028970 17883296
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.7418922899 8330346 18404319 12065085
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.1316537180
MESH:D020734 Parkinsonian Disorders Indomethacin 3.6212349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.1311903285
MESH:D010437 Peptic Ulcer Indomethacin 4.5711148446
MESH:D010438 Peptic Ulcer Hemorrhage Aspirin 4.9611156591
MESH:D010518 Periodontitis Indomethacin 4.3317225004
MESH:D020795 Photophobia Aspirin 5.1815240983
MESH:D003557 Phyllodes Tumor Doxorubicin 4.5717983394
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.3310923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.5717638057
MESH:D011014 Pneumonia Lipopolysaccharides 3.9812224865 11605937
MESH:D011230 Precancerous Conditions Cyclosporine 12.5012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 12.502563599
MESH:D011230 Precancerous Conditions Quercetin 12.5019056647
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.2021297632
MESH:D047928 Premature Birth Indomethacin 4.5617000239
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 8.1317132714
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 8.1316679765
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.2015572423
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.9917292933
MESH:D011471 Prostatic Neoplasms Calcitriol 1.9915754350 18247401 16289102 12479363 16644109
MESH:D011471 Prostatic Neoplasms Curcumin 1.9911398177 10851300 18156803 18226269 15129424 18769126 12497104
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.9916729912 16868541 18437689 15897917 16888761 15749863
MESH:D011471 Prostatic Neoplasms Quercetin 1.9914715546 17292933
MESH:D011471 Prostatic Neoplasms resveratrol 1.9917718901 17804756 15767336 17636462 17675339 16731767
MESH:D011471 Prostatic Neoplasms sulindac sulfone 1.9917908994 15570007
MESH:D011507 Proteinuria Indomethacin 3.6411849393
MESH:D011565 Psoriasis Cyclosporine 2.0016882103
MESH:D011656 Pulmonary Emphysema Curcumin 4.0219168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.7817365031 17975199 15814490 17322281
MESH:D051437 Renal Insufficiency Doxorubicin 3.6617922066
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.0016325855
MESH:D015427 Reperfusion Injury Capsaicin 9.2518460982 19211983
MESH:D015427 Reperfusion Injury pirinixic acid 9.2519058328
MESH:D015427 Reperfusion Injury resveratrol 9.2516317513 17520802 15827377 17058453 16314181
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 7.5518379247 10666014
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 7.5518379247 11700416
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.3410835634
MESH:D012220 Rhinitis Aspirin 3.8812372130
MESH:D012509 Sarcoma Curcumin 7.9018462866
MESH:D012509 Sarcoma Doxorubicin 7.9015675481 15625365 18313854 16767912 17710206 17203757
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.7014601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.2217846226
MESH:D012554 Schistosomiasis japonica Quercetin 4.9616862918
MESH:D018805 Sepsis Curcumin 3.6018389075
MESH:D012852 Sinusitis Phenylephrine 4.137327846
MESH:D012851 Sinus Thrombosis, Intracranial Aspirin 4.7012269725
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 14.7219755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 14.7215692506
MESH:D012878 Skin Neoplasms resveratrol 14.728985016 15837718
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 14.728532709
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 14.7218404319 12065085 8330346 8985016 11807781
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.0115625365 16767912 17203757
MESH:D013272 Stomach Diseases Dexamethasone 8.4715472012
MESH:D013272 Stomach Diseases Indomethacin 8.4716280098 10215738 18545984 10486359 15038085 15472012 18209964 10192188 17207306 17160473 16184426 17638125 16113693
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.1620155912 2093021
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.1618456281
MESH:D013274 Stomach Neoplasms Docosahexaenoic Acids 4.1619015929
MESH:D013274 Stomach Neoplasms Indomethacin 4.1615609394
MESH:D013276 Stomach Ulcer Curcumin 9.2519188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 9.2515138204
MESH:D013276 Stomach Ulcer Indomethacin 9.2516755016 11145282 10750652 17918041 15104355 18299717 16252198 11729361 10423059 18726076 16397915 17895592 12500499 11523592 18543354 11906479 12077510 18087811 10878458 18237397 1323529 11595415 17135157 16169175 15255614 17977527 15138204 18209962 18431645 11595431 17627676 17657623 16150113 14567935 16934674 17654042 18193104 18181030 12787963 12467913 12498302 16631530
MESH:D020521 Stroke Aspirin 3.9216403987
OMIM:601367 STROKE, ISCHEMIC resveratrol 3.9816321402
MESH:D013705 Temporomandibular Joint Disorders Capsaicin 5.1417997062
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.6615821434
MESH:D013927 Thrombosis Aspirin 4.0317672075
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 9.527505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 9.5216010429 17909728
MESH:D013964 Thyroid Neoplasms Indomethacin 9.5214736730 18791128 11352223
MESH:D014062 Tongue Neoplasms resveratrol 3.7116227395
MESH:D014456 Ulcer Indomethacin 4.3210574470 17380554
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 9.8117053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 9.8118593936
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 9.8117653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 9.8116720314
MESH:D014565 Urogenital Neoplasms Curcumin 4.6918462866
MESH:D014581 Urticaria Aspirin 3.9110982225 20485159
MESH:D002583 Uterine Cervical Neoplasms resveratrol 3.6017473185
MESH:D014594 Uterine Neoplasms resveratrol 13.1817044934
MESH:D014594 Uterine Neoplasms Sulindac 13.1818645019
MESH:D014594 Uterine Neoplasms sulindac sulfide 13.1818645019
MESH:D014605 Uveitis Cyclosporine 9.821336536
MESH:D014605 Uveitis Dexamethasone 9.821336536
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 8.4817638931 17678736 16364871 17334414
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.4817488730
MESH:D014839 Vomiting Indomethacin 4.1611897121
MESH:D015430 Weight Gain Dietary Fats 3.2516723640
MESH:D014985 Xerophthalmia Cyclosporine 3.8517120751
Pathway ID Pathway Name
KEGG:05221 Acute myeloid leukemia
REACT:71 Gene Expression
KEGG:05200 Pathways in cancer
KEGG:03320 PPAR signaling pathway
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33557
  • No data
    Releated disease ID Related disease Name
    PA445425Prostatic Neoplasms
    PA446969Venous Thrombosis
    PA446108Colorectal Neoplasms
    Releated drug ID Related drug Name
    PA449383docetaxel
    PA133950441hmg coa reductase inhibitors
    PA451644thalidomide
    PA164712669Coxibs
    PA10384antiinflammatory and antirheumatic products, non-steroids
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00159 agonist Icosapent Dietary supplement;Micronutrient
    DB00374 agonist Treprostinil Antithrombotic Agents;Antihypertensive Agents;Vitamin K antagonists
    DB00605 negative modulator Sulindac Antineoplastic Agents;Anti-inflammatory Agents;Cyclooxygenase Inhibitors;Analgesics;Analgesics, Non-Narcotic;Antipyretics;Nonsteroidal Anti-inflammatory Agents (NSAIAs)
    DB01393 agonist Hepaconda Antilipemic Agents
    DB03338 - Heptyl-Beta-D-Glucopyranoside
    DB04801 - (11E)-OCTADEC-11-ENOIC ACID
    DB07070 - (2S)-2-{3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]-4-methoxybenzyl}butanoic acid
    DB07691 - 2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid
    DB07724 - 3-{5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-1H-indol-3-yl}propanoic acid
    DB08078 - {4-[3-(4-acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy}acetic acid
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018