Annotation Detail for PPEF2
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D008070 |
Lipopolysaccharides |
Lipopolysaccharides results in increased expression of PPEF2 mRNA | increases expression | 12057914
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PPEF2 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| C034028 |
vanadyl sulfate |
vanadyl sulfate results in increased expression of PPEF2 mRNA | increases expression | 16330358
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
Lipopolysaccharides |
10.86 | 11850527 18653653 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
10.86 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D003921 |
Diabetes Mellitus, Experimental |
|
vanadyl sulfate |
4.76 | 16684804 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D019446 |
Endotoxemia |
|
Lipopolysaccharides |
5.14 | 15328337 17637181 15821434 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
| MESH:D005334 |
Fever |
|
Lipopolysaccharides |
4.46 | 11852909 9205823 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006463 |
Hemolytic-Uremic Syndrome |
|
Lipopolysaccharides |
4.83 | 16366002 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 18467677 19176532 19772884 16221962 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D007249 |
Inflammation |
|
Lipopolysaccharides |
3.06 | 17237260 9205823 17255318 17963957 12878042 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D019189 |
Iron Metabolism Disorders |
|
Lipopolysaccharides |
5.16 | 17255318 |
| MESH:D007970 |
Leukopenia |
|
Lipopolysaccharides |
5.44 | 15821434 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Lipopolysaccharides |
2.61 | 12878042 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
2.61 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 20007298 15890375 16377806 |
| MESH:D055370 |
Lung Injury |
|
Lipopolysaccharides |
4.66 | 21114838 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D011014 |
Pneumonia |
|
Lipopolysaccharides |
5.30 | 11605937 12224865 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
| MESH:D012130 |
Respiratory Hypersensitivity |
|
Lipopolysaccharides |
4.00 | 10835634 |
| MESH:D013921 |
Thrombocytopenia |
|
Lipopolysaccharides |
4.61 | 15821434 |
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