AutismKB 2.0

Annotation Detail for PPIB


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Basic Information Top
Gene Symbol:PPIB ( CYP-S1,CYPB,MGC14109,MGC2224,OI9,SCYLP )
Gene Full Name: peptidylprolyl isomerase B (cyclophilin B)
Band: 15q22.31
Quick LinksEntrez ID:5479; OMIM: 123841; Uniprot ID:PPIB_HUMAN; ENSEMBL ID: ENSG00000166794; HGNC ID: 9255
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200134Syndecan-1-mediated signaling events
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Related Diseases/Disorders Top
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Desease Name
Osteogenesis imperfecta, type IX
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C049325 1,2-dithiol-3-thione 1,2-dithiol-3-thione results in increased expression of PPIB mRNAincreases expression 15375163
C016392 3,3'-diindolylmethane 3,3'-diindolylmethane results in increased expression of PPIB mRNAincreases expression 16192472
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PPIB mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of PPIB proteinincreases expression 17292933
D016572 Cyclosporine Cyclosporine results in increased expression of PPIB mRNAincreases expression 20106945
D002945 Cisplatin Cisplatin results in decreased expression of PPIB mRNAdecreases expression 15033597
D004041 Dietary Fats Dietary Fats results in increased expression of PPIB mRNAincreases expression 18042831
D004958 Estradiol Estradiol results in increased expression of PPIB mRNAincreases expression 16192472
D000431 Ethanol Ethanol results in increased expression of PPIB mRNAincreases expression 15353170
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PPIB mRNAincreases expression 17555559
D005419 Flavonoids Flavonoids results in decreased expression of PPIB mRNAdecreases expression 18035473
D016627 Oxidopamine Oxidopamine results in increased expression of PPIB mRNAincreases expression 12486162
C016517 indole-3-carbinol indole-3-carbinol results in increased expression of PPIB mRNAincreases expression 16192472
D007657 Ketone Bodies Ketone Bodies results in increased expression of PPIB mRNAincreases expression 16807920
C008281 limonene limonene results in increased expression of PPIB mRNAincreases expression 12815608
D017239 Paclitaxel PPIB protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
C041786 palm oil palm oil results in increased expression of PPIB mRNAincreases expression 18042831
C006253 pirinixic acid pirinixic acid results in decreased expression of PPIB mRNAdecreases expression 15375163
D012643 Selenium Selenium results in increased expression of PPIB mRNAincreases expression 19244175
C004648 testosterone enanthate testosterone enanthate affects the expression of PPIB mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PPIB proteindecreases expression 16548065
D014810 Vitamin E Vitamin E results in increased expression of PPIB mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 8.0318926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.0311752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 10.0318287403
MESH:D000138 Acidosis Ethanol 10.0311192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D058186 Acute Kidney Injury Cisplatin 3.8415814532 17670903 12690470
MESH:D055371 Acute Lung Injury pirinixic acid 2.9918653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 9.9020127859 20464547
MESH:D000230 Adenocarcinoma Cisplatin 9.9011798837 17638652
MESH:D000230 Adenocarcinoma Estradiol 9.9011473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 9.9014692618
MESH:D000236 Adenoma Benzo(a)pyrene 2.586695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.4616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.4616835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.1915451039 15451040
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8311748828
MESH:D000853 Anophthalmos Ethanol 4.6915513904
MESH:D001008 Anxiety Disorders Ethanol 3.9011141031
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9419183758
MESH:D001161 Arteriosclerosis Dietary Fats 9.4715238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.4711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5815885639
MESH:D001289 Attention Deficit Disorder with Hyperactivity Oxidopamine 4.5714699433
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.3719483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.3712125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6815746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.7614601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.4415867366
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 3.6917474063 20146248
MESH:D001943 Breast Neoplasms Cisplatin 3.6918382427 19526202
MESH:D001943 Breast Neoplasms Dietary Fats 3.6920435547
MESH:D001943 Breast Neoplasms Estradiol 3.6917018787 12948864 18497071 17289903 14630087 16675129 17261762 19861407
MESH:D001943 Breast Neoplasms indole-3-carbinol 3.6916082211
MESH:D001943 Breast Neoplasms Paclitaxel 3.6916273361 15136595 16244791 18234424 18323546 18223236 11325840 16115903
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6920435547
MESH:D002056 Burns Ethanol 4.5216374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3316111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8016050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6916835633
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 6.4917982673
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.4916924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 6.4918788625 15763234 15289165
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 6.4916313753
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.9912023789 16685392
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.6320419170
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 4.6317066447 18337622 6189445
MESH:D006332 Cardiomegaly Ethanol 6.6119332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6118670907 18850075 16120746
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.2712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.2718566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0516835633
MESH:D002779 Cholestasis Cyclosporine 12.7819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 12.7816105132 17333356 16919318 17110522 17681005 15861022 11677210
MESH:D002779 Cholestasis pirinixic acid 12.7819176532
MESH:D002971 Cleft Lip Ethanol 3.5215513904
MESH:D002972 Cleft Palate Ethanol 5.7715513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7715668235 8697196 15340226 16354765 12621046
MESH:D003092 Colitis Selenium 3.6517936198
MESH:D015179 Colorectal Neoplasms Cisplatin 2.8515273666
MESH:D015179 Colorectal Neoplasms Paclitaxel 2.8518802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9514669216 17141729
MESH:D019465 Craniofacial Abnormalities Ethanol 3.7515513904 11198716 11873399 19302082 15451040 15451039 10194807
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.7519769572
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3718249437
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6417107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3019279558
MESH:D056486 Drug-Induced Liver Injury Ethanol 6.0511566570
MESH:D056486 Drug-Induced Liver Injury Selenium 6.0515131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.0520420201
MESH:D004362 Drug Toxicity Cisplatin 7.8612649298 12231392 15033597 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.8611462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3618367378
MESH:C538011 Eales disease Vitamin E 4.579068938
MESH:D004487 Edema pirinixic acid 6.1412083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.1411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0612538720
MESH:D016889 Endometrial Neoplasms Estradiol 2.9018566989 11473722 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9110568697 9294722
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.1916530937
MESH:D004938 Esophageal Neoplasms Cisplatin 10.1917638652 15173087 16481741 16785472 15464296
MESH:D004938 Esophageal Neoplasms Ethanol 10.1916704527
MESH:D004938 Esophageal Neoplasms Paclitaxel 10.1916481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9111564622
MESH:D005234 Fatty Liver Cyclosporine 23.3619224547
MESH:D005234 Fatty Liver Dietary Fats 23.3618296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver Ethanol 23.3616409862 19236843 18620774
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.3615345470
MESH:D005234 Fatty Liver pirinixic acid 23.3620131406 19236843
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.5417920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.1716946407 15513904 10194807 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3311858732
MESH:D005355 Fibrosis Cyclosporine 13.9612168785 12639820
MESH:D005355 Fibrosis Dietary Fats 13.9618296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.9620067830
MESH:D005756 Gastritis Ethanol 4.5615046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4710696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 3.6315102660 15464296
MESH:D034381 Hearing Loss Cisplatin 4.1819898482
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.3115464296
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.7120471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.7111294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 10.7116080930
MESH:D006333 Heart Failure pirinixic acid 6.6820558911
MESH:D006333 Heart Failure Selenium 6.6817162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2111000095
MESH:D006529 Hepatomegaly pirinixic acid 7.8316221962 18467677 19772884 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.8316120746 12621046 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6616863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.9015709030
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.6217440010
MESH:D006689 Hodgkin Disease Cisplatin 3.4816170182 16200630
MESH:D019584 Hot Flashes Estradiol 9.6217088409
MESH:D019584 Hot Flashes Vitamin E 9.6214716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9216354765 15340226 8697196 18606429 16959395
MESH:D006930 Hyperalgesia Ethanol 3.6118783367
MESH:D006937 Hypercholesterolemia Dietary Fats 3.4721332399
MESH:D006943 Hyperglycemia pirinixic acid 3.0720558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.4921332399
MESH:D006973 Hypertension Cyclosporine 4.7810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7818670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4017937319
MESH:D007249 Inflammation Dietary Fats 7.9220412841
MESH:D007249 Inflammation Flavonoids 7.9217296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.9212878042 12200463
MESH:D007251 Influenza, Human Selenium 10.5316624496
MESH:D007251 Influenza, Human Vitamin E 10.5316624496
MESH:D007333 Insulin Resistance Dietary Fats 11.8011836018 18457598
MESH:D007333 Insulin Resistance Estradiol 11.8016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 11.8016306350
MESH:D007569 Jaw Abnormalities Ethanol 9.7215513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.7216580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007673 Kidney Cortex Necrosis Cisplatin 5.0115464296
MESH:D007674 Kidney Diseases Cisplatin 13.8515190930 12649298 18289764 12231392 19839026
MESH:D007674 Kidney Diseases Cyclosporine 13.8518776723 8314463 10903974
MESH:D007674 Kidney Diseases Estradiol 13.8515618244
MESH:D007674 Kidney Diseases Vitamin E 13.8512488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.7616518626
MESH:D007680 Kidney Neoplasms Cyclosporine 6.9212371664
MESH:D007680 Kidney Neoplasms Estradiol 6.9215610895
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.6711231351
MESH:D007859 Learning Disorders Ethanol 4.0815451040
MESH:D017880 Limb Deformities, Congenital Ethanol 3.7217676605
MESH:D008080 Liposarcoma Paclitaxel 4.7017353645
MESH:D008103 Liver Cirrhosis Dietary Fats 6.6018296743
MESH:D008103 Liver Cirrhosis Ethanol 6.6015289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.9718295389
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.5614659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 6.5618166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.5615474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.5612878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.5616169303
MESH:D008107 Liver Diseases limonene 3.811715830
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.5217207112 17347304
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.0220195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 7.0220007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.0216984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 2.0312151625
MESH:D008171 Lung Diseases Vitamin E 3.0916863852
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.7320869020 18816296 18520028 18569708 6695378 20135361 20064080 20464547 17053015
MESH:D008175 Lung Neoplasms Cisplatin 4.736189445 17225452 11798837
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.7311884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 4.7311062179
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.9814749477
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.7411408345 16891317 17203775 11807958
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.7415318939
MESH:D020149 Manganese Poisoning Estradiol 4.3519453300
MESH:D008545 Melanoma Cisplatin 3.6712883367 16248763 12374674 16809738 18176117 16432458 11135225 15577323 17761969 18505091 18332650 12393984 17023156
MESH:D008545 Melanoma Paclitaxel 3.6712040289 16342250 12025231
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.6415990972
MESH:D008569 Memory Disorders Ethanol 4.0618411066 15451040
MESH:D008654 Mesothelioma Cisplatin 6.1917638057
MESH:D008654 Mesothelioma Selenium 6.1915107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0916381670
MESH:D009101 Multiple Myeloma Paclitaxel 3.5914749477
MESH:D009135 Muscular Diseases pirinixic acid 3.3816239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.0919151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.9116810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.9116411023
MESH:D009362 Neoplasm Metastasis Paclitaxel 3.2015867366
MESH:D009369 Neoplasms Benzo(a)pyrene 7.8911141357
MESH:D009369 Neoplasms Cisplatin 7.8916773208
MESH:D009369 Neoplasms pirinixic acid 7.8917405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6017289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.3615464296
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1718481113 19348381
MESH:D009421 Nervous System Malformations Estradiol 9.0416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.0414600291
MESH:D009447 Neuroblastoma Cisplatin 3.388761367
MESH:D019636 Neurodegenerative Diseases Oxidopamine 4.6518514411
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.578761367
MESH:D009765 Obesity Dietary Fats 4.3218674790 18457598 19632207 11836018 17217161 20132043 21332399 20518802 16723640
MESH:D009765 Obesity pirinixic acid 4.3220558911
OMIM:259440 OSTEOGENESIS IMPERFECTA, TYPE IX marker/mechanism
MESH:D010014 Osteolysis Paclitaxel 4.8515867366
MESH:D010051 Ovarian Neoplasms Cisplatin 7.7817225452 19769630 15464296 6897625
MESH:D010051 Ovarian Neoplasms Estradiol 7.7819401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 7.7811161223
MESH:D010190 Pancreatic Neoplasms Cisplatin 5.4919003803
MESH:D010190 Pancreatic Neoplasms Ethanol 5.4912384795
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010302 Parkinson Disease, Secondary Oxidopamine 5.3315893579 11771942
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1212520081
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 4.1815464296
MESH:D010954 Plasmacytoma Selenium 4.7615087411
MESH:D010997 Pleural Neoplasms Cisplatin 5.2117638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4318163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.1112371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0611118676 11896295 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7620887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.1117292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.1116740699
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.1117136230 16729912 16356831 17172428
MESH:D011471 Prostatic Neoplasms Vitamin E 2.1115084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.1816919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D051437 Renal Insufficiency Cisplatin 4.2815464296
MESH:D015427 Reperfusion Injury pirinixic acid 2.3219058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7118990726
MESH:D012512 Sarcoma, Ewing's Cisplatin 4.3014601052
MESH:D012640 Seizures Ethanol 3.089754883
MESH:D012871 Skin Diseases Vitamin E 2.4118709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.2719755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.2716192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.2115464296
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8116709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.6820155912 2093021
MESH:D013274 Stomach Neoplasms Cisplatin 4.6817522103 18396642 15958060
MESH:D013274 Stomach Neoplasms Ethanol 4.6818456281
MESH:D013274 Stomach Neoplasms Paclitaxel 4.6818396642 18506536
MESH:D013276 Stomach Ulcer Ethanol 3.4111906479 16755016 17918041 9211565 17189318 9562338
MESH:D020521 Stroke Vitamin E 3.4116517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.149754883
MESH:D024801 Tauopathies Paclitaxel 4.6816930453
MESH:D013736 Testicular Neoplasms Cisplatin 4.5117225452 15464296
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7712697716
MESH:D013978 Tibial Fractures Estradiol 4.5619048282
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.0417053015
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 5.0417225452 12973940 15464296
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 9.6816803524
MESH:D002583 Uterine Cervical Neoplasms indole-3-carbinol 9.6816082211
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1714692618
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.4815577323
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4215869587 14671159
MESH:D014839 Vomiting Cisplatin 4.5911897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1215886252
MESH:D015430 Weight Gain Dietary Fats 3.6216723640
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33580
    • No data
    Releated disease ID Related disease Name
    PA445180Osteogenesis Imperfecta
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00172 binder L-Proline Dietary supplement;Micronutrient;Non-Essential Amino Acids
    DB04447 - 1,4-Dithiothreitol
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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