AutismKB 2.0

Annotation Detail for KLHL24


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:KLHL24 ( DRE1,FLJ25796,KRIP6 )
Gene Full Name: kelch-like 24 (Drosophila)
Band: 3q27.1
Quick LinksEntrez ID:54800; OMIM: 611295; Uniprot ID:KLH24_HUMAN; ENSEMBL ID: ENSG00000114796; HGNC ID: 25947
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of KLHL24 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KLHL24 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of KLHL24 mRNAincreases expression 20458559
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of KLHL24 mRNAincreases expression 18687144
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of KLHL24 mRNAincreases expression 20064835
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of KLHL24 mRNAdecreases expression 20018196
C006780 bisphenol A bisphenol A results in decreased expression of KLHL24 mRNAdecreases expression 20678512
D003474 Curcumin Curcumin results in decreased expression of KLHL24 mRNAdecreases expression 17198877
D005472 Fluorouracil Fluorouracil results in increased expression of KLHL24 mRNAincreases expression 16510598
D019833 Genistein Genistein results in increased expression of KLHL24 mRNAincreases expression 18847459
C051890 irinotecan irinotecan analog results in increased expression of KLHL24 mRNAincreases expression 18927307
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of KLHL24 mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of KLHL24 mRNAdecreases expression 19270015
19482888
D010634 Phenobarbital Phenobarbital results in increased expression of KLHL24 mRNAincreases expression 19270015
D010656 Phenylephrine Phenylephrine results in decreased expression of KLHL24 mRNAdecreases expression 18158353
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of KLHL24 mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of KLHL24 mRNAincreases expression 18301758
D020849 Raloxifene Raloxifene results in increased expression of KLHL24 mRNAincreases expression 19429434
D012402 Rotenone Rotenone results in increased expression of KLHL24 mRNAincreases expression 19013527
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of KLHL24 mRNAaffects cotreatment|increases expression 19244175
C004648 testosterone enanthate testosterone enanthate affects the expression of KLHL24 mRNAaffects expression 17440010
C025643 vinclozolin vinclozolin affects the expression of KLHL24 mRNAaffects expression 19015723
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of KLHL24 mRNAaffects cotreatment|increases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.366195326
MESH:D000138 Acidosis Ammonium Chloride 3.4718287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.0318653653
MESH:D000230 Adenocarcinoma arsenic trioxide 10.0211798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 10.0220127859 20464547
MESH:D000230 Adenocarcinoma Fluorouracil 10.0217638652
MESH:D000230 Adenocarcinoma Genistein 10.0211473722
MESH:D000236 Adenoma Benzo(a)pyrene 2.606695378
MESH:D018248 Adenoma, Liver Cell Phenobarbital 9.8317620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 9.8316434500
MESH:D000419 Albuminuria Raloxifene 4.5117451421 17308373
MESH:D019973 Alcohol-Related Disorders Curcumin 5.0017887948
MESH:D000544 Alzheimer Disease Curcumin 4.3715590663
MESH:D000544 Alzheimer Disease Raloxifene 4.3715800139
MESH:D000740 Anemia Fluorouracil 3.6315504547 16511603 17963324
MESH:D000799 Angioedema Acetaminophen 3.7610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.5719015723
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.9919183758
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.0317460149
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.7216807698
MESH:D050197 Atherosclerosis Curcumin 3.2718704882
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001327 Autoimmune Diseases Curcumin 4.4019761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.7216206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.7219483382
MESH:D001862 Bone Resorption bisphenol A 3.7811985600
MESH:D001919 Bradycardia Phenylephrine 4.4615306635
MESH:D001930 Brain Injuries Raloxifene 4.3916580743
MESH:D002545 Brain Ischemia Curcumin 4.2516770732
MESH:D001932 Brain Neoplasms Curcumin 3.8617596214
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9320146248 17474063
MESH:D001943 Breast Neoplasms bisphenol A 2.9317123778
MESH:D001943 Breast Neoplasms Curcumin 2.9319250217 16243823 18593918 18462866
MESH:D001943 Breast Neoplasms Fluorouracil 2.9316595493 15136595 16557594 19217205 18608205 18357371 16110121
MESH:D001943 Breast Neoplasms Genistein 2.9316873071 17200150 16541309
MESH:D001943 Breast Neoplasms Raloxifene 2.9316912660 15775269 15572757 17242785 15758505 17440819 17893378 17595753 17049068 16837676 17952589 17261762
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2411589617
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8416050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5916051944
MESH:D002277 Carcinoma Curcumin 8.3318593918
MESH:D002277 Carcinoma Fluorouracil 8.3317121937
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.733084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.7315073043 16217749 15553829 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 8.7317971768 16332177 16799960 17045692 18930000 17088986
MESH:D006528 Carcinoma, Hepatocellular Genistein 8.7316924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 8.7317173139 20007298 1701930 20935162 6705139
MESH:D002278 Carcinoma in Situ bisphenol A 4.9017123778
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.9518414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7919014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9818695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0412490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.4420419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 7.4418462866
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.4418986760 16757204 16280240 17066447
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.9917572228
MESH:D006332 Cardiomegaly Phenylephrine 3.4811754973 11179087 17124262 16170337 15728586 17287366
MESH:D002318 Cardiovascular Diseases Genistein 7.3016332659
MESH:D002318 Cardiovascular Diseases Raloxifene 7.3015775269
MESH:D002386 Cataract Acetaminophen 2.5310977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.6620889678
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.164080065
MESH:D002779 Cholestasis pirinixic acid 2.7619176532
MESH:D003072 Cognition Disorders Raloxifene 4.5315800139
MESH:D003092 Colitis Curcumin 9.3816782535 16804969 18200517
MESH:D003092 Colitis Selenium 9.3817936198
MESH:D003103 Coloboma Curcumin 4.4718809619
MESH:D003110 Colonic Neoplasms Curcumin 8.2319359593 16340194
MESH:D003110 Colonic Neoplasms Fluorouracil 8.2317172411 15001691 17169374 17725105 17016597 16510598 17018589 16340194 18772588 17287894
MESH:D003110 Colonic Neoplasms Genistein 8.2317182828
MESH:D003110 Colonic Neoplasms irinotecan 8.2317287894 17725105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.4620501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.4616282729 18949393 17454858 17094418 17401013 15289873 18802399 17016601 16303861 17594712 18383874 18288408 17695437 16391804 20501625 17255274 18509181 14970324 16524972 18448328 16331619 15148649
MESH:D015179 Colorectal Neoplasms irinotecan 3.4617454858 18259882 15273666 16391804 18509181 17159606 16303861
MESH:D016510 Corneal Neovascularization Curcumin 4.8118497527
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.6810525206
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.6819769572
MESH:D003456 Cryptorchidism vinclozolin 4.2514966744
MESH:D007644 Darier Disease Fluorouracil 4.7116733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0115213294
MESH:D003865 Depressive Disorder, Major Raloxifene 4.0817474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.6418403477
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.6416647724
MESH:D003928 Diabetic Nephropathies Curcumin 8.9718204486
MESH:D003928 Diabetic Nephropathies Raloxifene 8.9715920148 17451421 17308373
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.7118071297 18713872 10915739 11739529 11287661 19164858 12392966 17906064 14725611 14550746 17522070 12540782 16781746 17562736 11421492 10663392 15968718 19923254 12958197 12594235 16109766 2444490 12705907 16485898 19416960 15619225 16081117 19420014 14986274 16393943 11461765 19370779 19085960 11743745 19739265 11529661 11834606 12153990 16227642 10774834 16177239
MESH:D056486 Drug-Induced Liver Injury Selenium 3.7115131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0219426721
MESH:D004381 Duodenal Ulcer Curcumin 3.9617351913
MESH:D004421 Dystonia Phenobarbital 3.921851702
MESH:C538011 Eales disease Vitamin E 4.629068938
MESH:D004487 Edema pirinixic acid 6.6212083418
MESH:D004487 Edema Raloxifene 6.6215860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 3.9115845917
MESH:D004714 Endometrial Hyperplasia Genistein 4.5016402032
MESH:D016889 Endometrial Neoplasms Genistein 3.3011473722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.023659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.793922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.8420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.466401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.167750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.933659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.2120426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 10.2112903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 10.2116530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 10.2116337965 16481741 15173087 16785472 17638652
MESH:D005234 Fatty Liver arsenic trioxide 18.1515073043
MESH:D005234 Fatty Liver Curcumin 18.1519297423
MESH:D005234 Fatty Liver pirinixic acid 18.1520131406 19236843
MESH:D005234 Fatty Liver Raloxifene 18.1517473493
MESH:D005355 Fibrosis Curcumin 3.9018705752
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1816904648
MESH:D005756 Gastritis Acetaminophen 3.5916983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.6118462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 4.8516973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.2216417039
MESH:D005909 Glioblastoma Curcumin 7.1917596214
MESH:D005909 Glioblastoma Genistein 7.1916598420
MESH:D005910 Glioma Fluorouracil 2.8316145905
MESH:D006258 Head and Neck Neoplasms Curcumin 7.7718829502 18462866
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.7718337622 15162350 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.5420471113
MESH:D006330 Heart Defects, Congenital Vitamin E 6.5416080930
MESH:D006331 Heart Diseases Raloxifene 3.4711110106
MESH:D006333 Heart Failure pirinixic acid 6.7720558911
MESH:D006333 Heart Failure Selenium 6.7717162251
MESH:D006529 Hepatomegaly Phenobarbital 8.1916109766
MESH:D006529 Hepatomegaly pirinixic acid 8.1919176532 19772884 18467677 16221962
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.9517701891
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6716863852 16490937
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.6717440010
MESH:D019584 Hot Flashes Vitamin E 3.8914716179
MESH:D006930 Hyperalgesia Acetaminophen 2.6316870215
MESH:D006937 Hypercholesterolemia Curcumin 3.9718704882
MESH:D006943 Hyperglycemia pirinixic acid 3.1020558911
MESH:D006973 Hypertension Phenylephrine 5.558949925 12717712
MESH:D006973 Hypertension Raloxifene 5.5515787275 17577099
MESH:D006984 Hypertrophy Phenylephrine 4.4718502941 12791704
MESH:D007248 Infertility, Male vinclozolin 2.9816467254
MESH:D007249 Inflammation Curcumin 2.8518403477 16956363 17151092
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.1718200517 18596194
MESH:D007251 Influenza, Human Selenium 10.6916624496
MESH:D007251 Influenza, Human Vitamin E 10.6916624496
MESH:D007333 Insulin Resistance bisphenol A 7.1216393666
MESH:D007333 Insulin Resistance pirinixic acid 7.1216306350
MESH:D007414 Intestinal Neoplasms Curcumin 4.1410783313
MESH:D007674 Kidney Diseases Acetaminophen 5.8015629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 5.8012488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.8016518626
MESH:D007680 Kidney Neoplasms Fluorouracil 3.2316985049
MESH:D007889 Leiomyoma Curcumin 10.8718555241
MESH:D007889 Leiomyoma Raloxifene 10.8716973256
MESH:D007938 Leukemia arsenic trioxide 10.3115070760
MESH:D007938 Leukemia Curcumin 10.3118462866
MESH:D007938 Leukemia Genistein 10.3118980019 17468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 9.4912560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 9.4916106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6819077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1220471514 16467208 16968895 17050201 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1616330433 15748426 11468182 17869043 16112521 19225113 19075265 12679006 16891316 17217047 15213294 12018890 12712474 16331271 9834237 16966277 17107899 16823087 19035177 15336539 17712046 11161223 19642359 15622746 17649720
MESH:D015458 Leukemia, T-Cell arsenic trioxide 11.4316882451
MESH:D015458 Leukemia, T-Cell Curcumin 11.4316106398
MESH:D007984 Leydig Cell Tumor vinclozolin 4.6516417039
MESH:D008103 Liver Cirrhosis Phenobarbital 2.8521047994
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 4.9118006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.9117823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9115474484
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9116169303
MESH:D008107 Liver Diseases Acetaminophen 6.4219014921 16610002 19460945 12587719 12969438 16611625 11587558 19784758
MESH:D008107 Liver Diseases Curcumin 6.4216956363
MESH:D008107 Liver Diseases Phenobarbital 6.4219363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1616871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 13.8914682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 13.8921137059 20195826
MESH:D008113 Liver Neoplasms Fluorouracil 13.8918383874 17045692 15113037 16603448
MESH:D008113 Liver Neoplasms Phenobarbital 13.8921047994 19812893 15975961 19482888 8742319 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 13.8920007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 5.8420377131
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 5.8417172636 2563599 1399818 18308698 6150874
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2815213294
MESH:D008171 Lung Diseases Vitamin E 3.1216863852
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.9417365036
MESH:D008175 Lung Neoplasms arsenic trioxide 6.4911798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.4918816296 20869020 20464547 6695378 18569708 18520028 17053015 20064080 20135361
MESH:D008175 Lung Neoplasms Curcumin 6.4916243823 19359593 18462866
MESH:D008175 Lung Neoplasms Fluorouracil 6.4915246190
MESH:D008175 Lung Neoplasms Vitamin E 6.4911062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.7115086387
MESH:D008223 Lymphoma Curcumin 3.5218462866
MESH:D016399 Lymphoma, T-Cell Curcumin 4.6116173963
MESH:D008325 Mammary Neoplasms, Experimental Genistein 5.9712929590 14578162
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.9715318939
MESH:D008545 Melanoma Curcumin 2.4017885582 18462866
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4819513568
MESH:D008569 Memory Disorders Curcumin 4.0717263510
MESH:D008654 Mesothelioma Asbestos, Crocidolite 6.2216166281 16966607 18303189
MESH:D008654 Mesothelioma Selenium 6.2215107826
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.4715863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.3016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.3016757204 18986760
MESH:D052016 Mucositis irinotecan 4.9217159606
MESH:D009101 Multiple Myeloma arsenic trioxide 11.8319417148 15949261 19549372 11468182 14977855
MESH:D009101 Multiple Myeloma Curcumin 11.8319372569
MESH:D009101 Multiple Myeloma Raloxifene 11.8316497877
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.8317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.4216239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0916105982 16882451
MESH:D009203 Myocardial Infarction Genistein 5.5617141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.5619151258
MESH:D015428 Myocardial Reperfusion Injury Genistein 8.1617141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.1616411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3917484760
MESH:D009232 Myxoma Raloxifene 5.4716343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 10.0416624393
MESH:D009361 Neoplasm Invasiveness Curcumin 10.0418495463
MESH:D009362 Neoplasm Metastasis irinotecan 3.1418259882
MESH:D009369 Neoplasms Benzo(a)pyrene 7.9611141357
MESH:D009369 Neoplasms Fluorouracil 7.9618600527 18239605 16928823
MESH:D009369 Neoplasms pirinixic acid 7.9617405874
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 4.4512497104
MESH:D009410 Nerve Degeneration Rotenone 3.8117356569 18619942 15790535
MESH:D009421 Nervous System Malformations bisphenol A 9.6011399458 16427766
MESH:D009421 Nervous System Malformations Genistein 9.6016427766
MESH:D009423 Nervous System Neoplasms Curcumin 5.5518462866
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0610525206
MESH:D009447 Neuroblastoma irinotecan 3.438761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8018514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.648761367
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3816436463
MESH:D009765 Obesity Curcumin 4.5319297423
MESH:D009765 Obesity pirinixic acid 4.5320558911
MESH:D010018 Osteomalacia Phenobarbital 4.2817016548
MESH:D010024 Osteoporosis Curcumin 11.6518719352
MESH:D010024 Osteoporosis Genistein 11.6519401787
MESH:D010024 Osteoporosis Raloxifene 11.6519059307 15775268 17882678
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.8616169203
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 9.8615579764 17823083 15758505 17893378
MESH:D010049 Ovarian Diseases bisphenol A 4.9011985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.8319769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 7.8318462866 19020741
MESH:D010051 Ovarian Neoplasms Genistein 7.8319005980
MESH:D010146 Pain Acetaminophen 2.3216870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 12.1115580305
MESH:D010190 Pancreatic Neoplasms Curcumin 12.1119401701 19196508 17440100
MESH:D010190 Pancreatic Neoplasms Fluorouracil 12.1116929163 19003803 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 12.1116965848
MESH:D010235 Paraganglioma arsenic trioxide 4.0819927285
MESH:D010300 Parkinson Disease Rotenone 2.9511445065 16412576 15451049 19232380 11535288 18191903 19114014 16140633 18619942
MESH:D020734 Parkinsonian Disorders Rotenone 4.0015927086 18197244 15795934 15574749
MESH:D010954 Plasmacytoma Selenium 4.8115087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.8110923243
MESH:D011230 Precancerous Conditions Phenobarbital 3.552563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 9.4810548101
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 9.4818220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 4.8518220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.1220887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.4519131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.4517292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.4516740699
MESH:D011471 Prostatic Neoplasms Curcumin 2.4511398177 18769126 18226269 15129424 18156803 12497104 10851300
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.4519082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 2.4515256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Raloxifene 2.4516220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms Vitamin E 2.4515084515
MESH:D011472 Prostatitis vinclozolin 4.8518629315
MESH:D019310 Pseudolymphoma Phenobarbital 4.4112752131
MESH:D011629 Puberty, Precocious bisphenol A 4.7010548101
MESH:D011656 Pulmonary Emphysema Curcumin 4.4519168576
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.0017322281 17975199 17365031 15814490
MESH:D011693 Purpura Raloxifene 5.4715770314
MESH:D012004 Rectal Neoplasms Fluorouracil 3.9316160472 15538739 18286688 18722050
MESH:D015427 Reperfusion Injury pirinixic acid 2.3419058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.9418379247 10666014
MESH:D012509 Sarcoma Curcumin 4.0418462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8716646077
MESH:D012640 Seizures Phenobarbital 2.634039156 3137016 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 4.746407741
MESH:D018805 Sepsis Curcumin 4.0018389075
MESH:D012852 Sinusitis Phenylephrine 4.627327846
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.3319755658 10029692
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.6717007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 4.6720155912 2093021
MESH:D013274 Stomach Neoplasms Fluorouracil 4.6715786421 16951190 18567086 17522103 17498489 16424979 19084572 18396642 17172411 19015929
MESH:D013274 Stomach Neoplasms irinotecan 4.6715723263
MESH:D013276 Stomach Ulcer Curcumin 3.4219188055 16631530
MESH:D020521 Stroke Raloxifene 8.4716837676
MESH:D020521 Stroke Vitamin E 8.4716517955
MESH:D019966 Substance-Related Disorders bisphenol A 3.9016684133 16045194
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.9919014326
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.991399818
MESH:D013978 Tibial Fractures Raloxifene 5.1319048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.9116280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8815213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 11.6912845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 11.6917053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 11.6918593936
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 11.6917572228
MESH:D014565 Urogenital Neoplasms Curcumin 5.1818462866
MESH:D014581 Urticaria Acetaminophen 2.8910982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.8016803524
MESH:D014591 Uterine Diseases bisphenol A 4.9314652134
MESH:D054556 Venous Thromboembolism Raloxifene 5.1316837676
MESH:D014846 Vulvar Neoplasms Raloxifene 5.4716343187
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved