AutismKB 2.0

Annotation Detail for GDAP2


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Basic Information Top
Gene Symbol:GDAP2 ( FLJ20142,dJ776P7.1 )
Gene Full Name: ganglioside induced differentiation associated protein 2
Band: 1p12
Quick LinksEntrez ID:54834; OMIM: NA; Uniprot ID:GDAP2_HUMAN; ENSEMBL ID: ENSG00000196505; HGNC ID: 18010
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of GDAP2 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of GDAP2 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GDAP2 mRNAdecreases expression 20018196
D016572 Cyclosporine Cyclosporine results in increased expression of GDAP2 mRNAincreases expression 20106945
D008345 Manganese Manganese results in increased expression of GDAP2 mRNAincreases expression 17175027
C025340 manganese chloride manganese chloride results in increased expression of GDAP2 mRNAincreases expression 17175027
D010100 Oxygen Oxygen deficiency results in increased expression of GDAP2 mRNAincreases expression 17175027
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury Oxygen 4.8316759491
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.903712494
MESH:D000756 Anemia, Sideroblastic Manganese 11.9916910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 11.9916910769
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D000860 Anoxia Oxygen 5.4520872349
MESH:D050197 Atherosclerosis Oxygen 3.9516391483
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.461440618 11289319
MESH:D001943 Breast Neoplasms Oxygen 3.2017263869
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 2.923581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.923084413
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.787296757
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 12.227505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.2220889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.2212371664
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.5619486331 9022650
MESH:D002779 Cholestasis Cyclosporine 8.5619486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.1511906362 18759878 8156756 14531868 12868966 2524372 8970840 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.792952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 3.9418289764 18648102 18692083 1440618 9022650 8291058 7440962 9653073 11289319 16192314 6482804 9328219 6679447
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.942444490 18071297 19923254 16109766 11529661 16081117 16485898 11287661 14550746 14986274 10774834 19416960 15619225 14725611 17562736 12705907 12540782 15968718 12594235 16227642 19370779 12392966 11739529 10915739 11743745 19085960 19164858 16177239 19420014 16393943 17906064 16781746 12153990 11421492 10663392 11461765 18713872 19739265 11834606 12958197 17522070
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D004417 Dyspnea Oxygen 5.2720016425
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.583581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5820426865
MESH:D005234 Fatty Liver Cyclosporine 3.1419224547
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.466705139
MESH:D005355 Fibrosis Cyclosporine 3.5012168785 12639820
MESH:D005739 Gas Poisoning Oxygen 5.6620016425
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D005909 Glioblastoma Manganese 4.0817043766
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.347505956
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.846705139
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.3015034207
MESH:D006973 Hypertension Cyclosporine 2.1810903974
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.468074119 9022650
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Acetaminophen 6.2815629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.2818776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.066582329
MESH:D007680 Kidney Neoplasms Cyclosporine 8.0612371664
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.359327722 15034207
MESH:D008107 Liver Diseases Acetaminophen 1.6812587719 19014921 16611625 19460945 11587558 12969438 16610002 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.691399818 598648 3712494 6587162
MESH:D055370 Lung Injury Oxygen 4.8718339021
MESH:D020149 Manganese Poisoning Manganese 5.9619453300 16551646 16568477
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D009069 Movement Disorders Manganese 5.3116551646
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.563581430
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5318481113 19348381
MESH:D009410 Nerve Degeneration Manganese 4.4816551646
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.086679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.686482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.463988306
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.847296757
MESH:D010300 Parkinson Disease Manganese 3.4511181820
MESH:D020734 Parkinsonian Disorders Manganese 4.7316140633
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.916228378
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D012128 Respiratory Distress Syndrome, Adult Oxygen 4.8118339021 17627322
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.583692021
MESH:D013398 Sudden Infant Death Oxygen 5.9412563064
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.096582329 6587162 3712494 7505956 1399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.368074119
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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