Annotation Detail for CC2D1A
Basic Information Top
| Gene Symbol: | CC2D1A ( FLJ20241,FLJ41160,FREUD-1,Freud-1/Aki1,MRT3 ) |
|---|---|
| Gene Full Name: | coiled-coil and C2 domain containing 1A |
| Band: | 19p13.12 |
| Quick Links | Entrez ID:54862; OMIM: 610055; Uniprot ID:C2D1A_HUMAN; ENSEMBL ID: ENSG00000132024; HGNC ID: 30237 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| No data |
| No data |
| Desease Name |
|---|
| Mental retardation, autosomal recessive 3 |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of CC2D1A mRNA | affects expression | 17562736 |
| C006253 | pirinixic acid | pirinixic acid results in decreased expression of CC2D1A mRNA | decreases expression | 17426115 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.72 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.37 | 16434500 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.70 | 19483382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.19 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.61 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 12594235 17906064 10774834 11421492 19923254 17522070 19370779 12705907 16081117 12958197 16393943 11287661 2444490 14986274 16177239 18071297 19085960 10915739 19164858 14725611 12392966 16227642 11743745 11834606 16485898 12153990 15619225 11529661 16109766 12540782 15968718 16781746 19420014 19739265 18713872 14550746 11739529 11461765 17562736 19416960 10663392 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D004487 | Edema | pirinixic acid | 3.02 | 12083418 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.31 | 19236843 20131406 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.81 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.76 | 18467677 16221962 19772884 19176532 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.69 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.93 | 16306350 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 12587719 15629191 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19014921 16610002 19784758 11587558 19460945 16611625 12969438 12587719 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.95 | 15890375 16377806 20007298 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| OMIM:608443 | MENTAL RETARDATION, AUTOSOMAL RECESSIVE 3 | marker/mechanism | |||
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.27 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.30 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.33 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.14 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.90 | 20558911 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.58 | 19058328 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| No data |
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| Releated disease ID | Related disease Name |
|---|---|
| PA444929 | Mental Retardation |
| PA161615744 | Mental Retardation, Autosomal Recessive |
| No data |