AutismKB 2.0

Annotation Detail for CASZ1


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Basic Information Top
Gene Symbol:CASZ1 ( CST,FLJ12223,FLJ20321,SRG,ZNF693,dJ734G22.1 )
Gene Full Name: castor zinc finger 1
Band: 1p36.22
Quick LinksEntrez ID:54897; OMIM: 609895; Uniprot ID:CASZ1_HUMAN; ENSEMBL ID: ENSG00000130940; HGNC ID: 26002
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CARDIOVASCULAR
systolic blood pressure
Desease Name
Systolic blood pressure
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CASZ1 mRNAaffects expression 17562736
C014347 decitabine decitabine results in increased expression of CASZ1 mRNAincreases expression 17940511
C024746 tobacco tar tobacco tar results in decreased expression of CASZ1 mRNAdecreases expression 19559774
C012589 trichostatin A trichostatin A results in increased expression of CASZ1 mRNAincreases expression 17940511
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms decitabine 2.5318320071 19208741
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6819215824
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 4.2019559774
MESH:D003110 Colonic Neoplasms decitabine 2.3817616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1118981723
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6719739265 18071297 11287661 19416960 16177239 11529661 17906064 19370779 17522070 10663392 11421492 11739529 15968718 14550746 10915739 12540782 12594235 16485898 16227642 11743745 14986274 17562736 19420014 12705907 19164858 10774834 16081117 18713872 12958197 12392966 19923254 14725611 15619225 12153990 2444490 16781746 19085960 11461765 16109766 16393943 11834606
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004701 Endocrine Gland Neoplasms decitabine 16.5819294695
MESH:D004701 Endocrine Gland Neoplasms trichostatin A 16.5819294695
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D005909 Glioblastoma trichostatin A 4.0718801729
MESH:D006258 Head and Neck Neoplasms decitabine 3.7419215824
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D007248 Infertility, Male decitabine 3.4517581917
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D007938 Leukemia decitabine 3.2418980019 19235587
MESH:D007951 Leukemia, Myeloid decitabine 4.4317236224 19117987 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.4618460780 19387464 17679729 18704418 18206229 19010910
MESH:D015470 Leukemia, Myeloid, Acute trichostatin A 4.4618206229
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.1918055864
MESH:D008107 Liver Diseases Acetaminophen 1.7019784758 11587558 12969438 19014921 16611625 19460945 16610002 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D008223 Lymphoma decitabine 3.6919470736
MESH:D008545 Melanoma decitabine 3.8917785578 16505122
MESH:D008545 Melanoma trichostatin A 3.8916505122
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009101 Multiple Myeloma decitabine 8.5918172295
MESH:D009101 Multiple Myeloma trichostatin A 8.5918172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5818608210 19157545 19010910 16882708
MESH:D009369 Neoplasms decitabine 2.8719116145 17925555 19470736
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2118514411
MESH:D010051 Ovarian Neoplasms decitabine 5.6019331143 19259094
MESH:D010051 Ovarian Neoplasms trichostatin A 5.6019331143
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D010190 Pancreatic Neoplasms decitabine 6.0619294695
MESH:D010190 Pancreatic Neoplasms trichostatin A 6.0619294695
MESH:D055728 Primary Myelofibrosis decitabine 14.3717616702
MESH:D055728 Primary Myelofibrosis trichostatin A 14.3717616702
MESH:D011471 Prostatic Neoplasms trichostatin A 3.9818798265 19789329
MESH:D012208 Rhabdomyosarcoma decitabine 4.8719155313
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013964 Thyroid Neoplasms decitabine 3.6317967635
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.8419087683 17616700
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014604 Uveal Neoplasms decitabine 5.6417785578
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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