Annotation Detail for WHSC1L1
Basic Information
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| Gene Symbol: | WHSC1L1 ( DKFZp667H044,FLJ20353,MGC126766,MGC142029,NSD3,pp14328 ) |
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| Gene Full Name: | Wolf-Hirschhorn syndrome candidate 1-like 1 |
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| Band: | 8p11.2 |
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| Quick Links | Entrez ID:54904; OMIM: 607083; Uniprot ID:NSD3_HUMAN; ENSEMBL ID: ENSG00000147548; HGNC ID: |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00310 | Lysine degradation |
| Desease Name |
|---|
| Leukemia, acute myeloid |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004958 |
Estradiol |
Estradiol results in decreased expression of WHSC1L1 mRNA | decreases expression | 20068009
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of WHSC1L1 mRNA | affects expression | 19015723
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
Estradiol |
2.18 | 11473722 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
4.05 | 19015723 |
| MESH:D001943 |
Breast Neoplasms |
|
Estradiol |
2.10 | 19861407 12948864 17018787 17289903 16675129 14630087 17261762 18497071 |
| MESH:D002181 |
Candidiasis, Vulvovaginal |
|
Estradiol |
5.35 | 16111702 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Estradiol |
1.80 | 16924424 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Estradiol |
3.09 | 18566989 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
5.02 | 14966744 |
| MESH:D003928 |
Diabetic Nephropathies |
|
Estradiol |
3.88 | 19279558 |
| MESH:D016889 |
Endometrial Neoplasms |
|
Estradiol |
3.28 | 19148513 18566989 11473722 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.82 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
6.37 | 16417039 |
| MESH:D006558 |
Herpes Genitalis |
|
Estradiol |
6.10 | 15709030 |
| MESH:D019584 |
Hot Flashes |
|
Estradiol |
4.82 | 17088409 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.35 | 16467254 |
| MESH:D007333 |
Insulin Resistance |
|
Estradiol |
3.26 | 16627594 16393666 |
| MESH:D007674 |
Kidney Diseases |
|
Estradiol |
2.83 | 15618244 |
| MESH:D007680 |
Kidney Neoplasms |
|
Estradiol |
3.41 | 15610895 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
marker/mechanism |
|
| |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.62 | 16417039 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Estradiol |
1.69 | 14659978 14716833 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Estradiol |
2.85 | 11807958 17203775 16891317 11408345 |
| MESH:D020149 |
Manganese Poisoning |
|
Estradiol |
5.55 | 19453300 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
Estradiol |
3.66 | 16810080 |
| MESH:D009389 |
Neovascularization, Pathologic |
|
Estradiol |
4.62 | 17289903 |
| MESH:D009421 |
Nervous System Malformations |
|
Estradiol |
4.32 | 11399458 16427766 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Estradiol |
2.33 | 19401270 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.78 | 18042343 19015723 18220299 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.82 | 18220299 |
| MESH:D019048 |
Prostatic Intraepithelial Neoplasia |
|
Estradiol |
4.44 | 20887781 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Estradiol |
3.01 | 16740699 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.82 | 18629315 |
| MESH:D013978 |
Tibial Fractures |
|
Estradiol |
5.76 | 19048282 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:00310 |
Lysine degradation |
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