AutismKB 2.0

Annotation Detail for RASIP1


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Basic Information Top
Gene Symbol:RASIP1 ( FLJ20401,RAIN )
Gene Full Name: Ras interacting protein 1
Band: 19q13.33
Quick LinksEntrez ID:54922; OMIM: 609623; Uniprot ID:RAIN_HUMAN; ENSEMBL ID: ENSG00000105538; HGNC ID: 24716
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RASIP1 mRNAaffects expression 17562736
D004041 Dietary Fats Dietary Fats results in increased expression of RASIP1 mRNAincreases expression 18042831
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RASIP1 mRNAaffects expression 17555576
D005047 Etoposide RASIP1 protein affects the susceptibility to Etoposideaffects response to substance 16217747
C041786 palm oil palm oil results in increased expression of RASIP1 mRNAincreases expression 18042831
D013629 Tamoxifen Tamoxifen affects the expression of RASIP1 mRNAaffects expression 17555576
C025643 vinclozolin vinclozolin affects the expression of RASIP1 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.9914745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3817505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D000799 Angioedema Acetaminophen 4.2910982225
MESH:D001008 Anxiety Disorders vinclozolin 3.8619015723
MESH:D001161 Arteriosclerosis Dietary Fats 11.1315238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 11.1311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8215885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D019046 Bone Marrow Neoplasms Etoposide 5.6014601052
MESH:D001943 Breast Neoplasms Dietary Fats 2.0120435547
MESH:D001943 Breast Neoplasms Etoposide 2.0116322251
MESH:D001943 Breast Neoplasms Tamoxifen 2.0119288272 19221464 18855134 19142967 17242785 19155303 20005174 16873071 18984771 17440819 20065188 19189212 18629630 20135344 19059307 19189210 16273361 17049068 20859285 19487384 18425577 16202921 18821012 21138602 19103187 20544844 17261762 19084267 19289846 21152245 19244106 19115204 16818667 18351453 19066611 19011961 18997820 11161223 20390343 15565566 19200415 15668708 17893378 18815881 19410462
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.8719066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.953084413
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 2.9516924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.8817572228
MESH:D002386 Cataract Acetaminophen 2.7310977129
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0717110522 16919318 17333356 17681005 15861022 16105132 11677210
MESH:D003456 Cryptorchidism vinclozolin 4.6714966744
MESH:D003711 Demyelinating Diseases Tamoxifen 4.7219031437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.7219279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6511529661 14725611 19164858 18071297 2444490 11739529 16485898 12705907 19420014 16109766 17562736 19739265 10774834 16081117 11421492 16177239 12594235 11461765 14550746 12958197 17522070 10915739 16393943 11287661 15619225 19416960 19370779 16781746 12392966 16227642 15968718 10663392 12153990 18713872 12540782 11834606 19923254 17906064 11743745 14986274 19085960
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.5419426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6518367378
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.0612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.0619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2116202921 19155303 20544844 17893378
MESH:D005234 Fatty Liver Dietary Fats 14.8118296743 19551842 17967931 19004024
MESH:D005234 Fatty Liver Ethinyl Estradiol 14.8115345470
MESH:D005234 Fatty Liver Tamoxifen 14.8119224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.3916709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.9214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.5819069698
MESH:D005355 Fibrosis Dietary Fats 3.8818296743
MESH:D005756 Gastritis Acetaminophen 4.1216983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.3316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.7416417039
MESH:D006561 Herpes Simplex Etoposide 4.9610809021
MESH:D006689 Hodgkin Disease Etoposide 4.1115147373 18180244 16135485 16200630 17606976
MESH:D006930 Hyperalgesia Acetaminophen 2.9216870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8721332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9221332399
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.2517937319
MESH:D007248 Infertility, Male vinclozolin 7.2516467254
MESH:D007249 Inflammation Dietary Fats 5.5320412841
MESH:D007249 Inflammation Tamoxifen 5.5319457130
MESH:D007333 Insulin Resistance Dietary Fats 3.2718457598 11836018
MESH:D007674 Kidney Diseases Acetaminophen 2.3412587719 15629191
MESH:D007680 Kidney Neoplasms Tamoxifen 3.2718625569
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1316417039
MESH:D008064 Lipidoses Tamoxifen 3.3517567588 15342952
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0118296743
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008107 Liver Diseases Acetaminophen 1.6812587719 16611625 16610002 12969438 11587558 19014921 19460945 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5016871587 17185352
MESH:D008113 Liver Neoplasms Tamoxifen 2.3016684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D008223 Lymphoma Etoposide 4.1112556972 12854902
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.1519428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.7914580682 16827153 11731420 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.9919453300
MESH:D008545 Melanoma Tamoxifen 1.9112393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.5815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9319513568
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5919410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.4419189210 19196722 19200415
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1018514411
MESH:D009765 Obesity Dietary Fats 2.3420518802 19632207 16723640 21332399 17217161 18457598 11836018 20132043 18674790
MESH:D010146 Pain Acetaminophen 2.6216870215
MESH:D010190 Pancreatic Neoplasms Etoposide 3.3519003803
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9911578682
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.2918042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.3318220299
MESH:D011471 Prostatic Neoplasms Etoposide 3.4517172428
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.4515067354
MESH:D011472 Prostatitis vinclozolin 5.3318629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.7116919318 15861022
MESH:D012512 Sarcoma, Ewing's Etoposide 5.0314601052
MESH:D013088 Spermatocele Ethinyl Estradiol 13.0916709447
MESH:D013088 Spermatocele Tamoxifen 13.0916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.4319457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4015669648
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.448653321 16712894 17572228
MESH:D014581 Urticaria Acetaminophen 3.2810982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6314692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8215869587 14671159
MESH:D015430 Weight Gain Dietary Fats 3.9916723640
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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