Annotation Detail for LIME1
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of LIME1 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| D012643 |
Selenium |
Selenium results in increased expression of LIME1 mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.72 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.37 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.70 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.19 | 19176532 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.54 | 17936198 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.61 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
2.27 | 15131321 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
3.02 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.31 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
7.86 | 20558911 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
7.86 | 17162251 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.76 | 16221962 19772884 19176532 18467677 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.69 | 20558911 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
5.27 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.93 | 16306350 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.44 | 16518626 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.95 | 16377806 20007298 15890375 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
3.05 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.94 | 15107826 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.27 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.30 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.33 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.14 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.90 | 20558911 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.96 | 15087411 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.58 | 19058328 |
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