AutismKB 2.0

Annotation Detail for C12orf41


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Basic Information Top
Gene Symbol:C12orf41 ( FLJ12670,FLJ20436 )
Gene Full Name: chromosome 12 open reading frame 41
Band: 12q13.11
Quick LinksEntrez ID:54934; OMIM: NA; Uniprot ID:CL041_HUMAN; ENSEMBL ID: ENSG00000139620; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D016572 Cyclosporine Cyclosporine results in increased expression of C12ORF41 mRNAincreases expression 20106945
D012643 Selenium Selenium results in decreased expression of C12ORF41 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8512371664
MESH:D002779 Cholestasis Cyclosporine 3.2819486331
MESH:D003092 Colitis Selenium 4.5417936198
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2715131321
MESH:D005234 Fatty Liver Cyclosporine 3.4019224547
MESH:D005355 Fibrosis Cyclosporine 3.9012168785 12639820
MESH:D005885 Gingival Hyperplasia Cyclosporine 5.118708960
MESH:D006333 Heart Failure Selenium 3.3417162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.3115720958
MESH:D006973 Hypertension Cyclosporine 2.2410903974
MESH:D007251 Influenza, Human Selenium 5.2716624496
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.5115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.5818776723 10903974 8314463
MESH:D007676 Kidney Failure, Chronic Selenium 4.4416518626
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1712371664
MESH:D008325 Mammary Neoplasms, Experimental Selenium 3.0515318939
MESH:D008654 Mesothelioma Selenium 2.9415107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.8616801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.5117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7518481113 19348381
MESH:D010954 Plasmacytoma Selenium 5.9615087411
MESH:D011230 Precancerous Conditions Cyclosporine 3.6912371664
MESH:D011565 Psoriasis Cyclosporine 2.3516882103
MESH:D014605 Uveitis Cyclosporine 5.051336536
MESH:D014985 Xerophthalmia Cyclosporine 5.5117120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018