Annotation Detail for SARS2
Basic Information
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| Gene Symbol: | SARS2 ( FLJ20450,SARS,SARSM,SERS,SYS,SerRS,SerRSmt,mtSerRS ) |
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| Gene Full Name: | seryl-tRNA synthetase 2, mitochondrial |
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| Band: | 19q13.2 |
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| Quick Links | Entrez ID:54938; OMIM: 612804; Uniprot ID:SYSM_HUMAN; ENSEMBL ID: ENSG00000104835; HGNC ID: 17697 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00970 | Aminoacyl-tRNA biosynthesis |
| Pathway ID | Pathway Name |
|---|
| Gene Expression |
| Pathway ID | Pathway Name |
|---|
| 500661 | Mitochondrial tRNA aminoacylation |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of SARS2 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of SARS2 mRNA | affects expression | 21346803
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
3.13 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
3.13 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.09 | 6135515 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
13.58 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
13.58 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.22 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
4.22 | 18551238 21346803 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.84 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.84 | 16705839 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.29 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.82 | 6135515 2876786 2876784 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
13.53 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
13.53 | 7678174 18551238 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.61 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.61 | 16049721 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.95 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.95 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.52 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.52 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
15.17 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
15.17 | 10091137 |
Related Diseases/Disorders