AutismKB 2.0

Annotation Detail for PPM1A


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Basic Information Top
Gene Symbol:PPM1A ( FLJ42306,MGC9201,PP2C-ALPHA,PP2CA,PP2Calpha )
Gene Full Name: protein phosphatase, Mg2+/Mn2+ dependent, 1A
Band: 14q23.1
Quick LinksEntrez ID:5494; OMIM: 606108; Uniprot ID:PPM1A_HUMAN; ENSEMBL ID: ENSG00000100614; HGNC ID: 9275
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
Pathway IDPathway Name
Signaling by Insulin receptor
Pathway IDPathway Name
200123BMP receptor signaling
200152Regulation of cytoplasmic and nuclear SMAD2/3 signaling
No data
Pathway IDPathway Name
500502Regulation of AMPK activity via LKB1
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of PPM1A mRNAaffects expression 17562736
D013196 Dihydrotestosterone Dihydrotestosterone results in decreased expression of PPM1A mRNAdecreases expression 17023530
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PPM1A mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in decreased expression of PPM1A mRNAdecreases expression 20458559
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of PPM1A mRNAdecreases expression 20064835
C053342 brevetoxin brevetoxin analog results in decreased expression of PPM1A mRNAdecreases expression 14529743
C053342 brevetoxin brevetoxin analog results in increased expression of PPM1A mRNAincreases expression 14529743
D003024 Clozapine Clozapine results in decreased expression of PPM1A mRNAdecreases expression 15860345
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PPM1A mRNAincreases expression 17942748
17555576
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPM1A mRNAaffects cotreatment|increases expression 17942748
D006220 Haloperidol Haloperidol results in decreased expression of PPM1A mRNAdecreases expression 15860345
D018817 N-Methyl-3,4-methylenedioxyamphetamine N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of PPM1A mRNAincreases expression 19285098
C006253 pirinixic acid pirinixic acid results in increased expression of PPM1A mRNAincreases expression 17426115
18301758
D013629 Tamoxifen Tamoxifen affects the expression of PPM1A mRNAaffects expression 17555576
C004648 testosterone enanthate testosterone enanthate affects the expression of PPM1A mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPM1A mRNAaffects cotreatment|increases expression 17942748
D014635 Valproic Acid Valproic Acid results in increased expression of PPM1A mRNAincreases expression 19101580
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6114745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4811752688 15322242 14514962
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 8.488875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.9619490988
MESH:D000138 Acidosis Ammonium Chloride 3.6118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 7.0719825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 7.0720464547 20127859
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.0714692618
MESH:D000236 Adenoma Benzo(a)pyrene 2.676695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.0716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.0716835633
MESH:D000380 Agranulocytosis Clozapine 5.1016160616 14617031 12649775
MESH:D000550 Amblyopia Valproic Acid 5.3017688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D000855 Anorexia N-Methyl-3,4-methylenedioxyamphetamine 5.3415146954
MESH:D001008 Anxiety Disorders Valproic Acid 3.5917497229
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1219183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6815885639
MESH:D001321 Autistic Disorder Acetaminophen 2.2118445737
MESH:D001321 Autistic Disorder Haloperidol 2.2118080171 19368416
MESH:D001321 Autistic Disorder Valproic Acid 2.2115238991 17688650 19232924 18316065 20603192 16609825 18396377 17157402 19460635 17507914 18985861 18775368 18940202 18177632 18558336
MESH:D001714 Bipolar Disorder Valproic Acid 3.0920046352 17594078
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 15.4616206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 15.4619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 15.4612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 8.0815746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 8.088888407
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8020146248 17474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.8016818667 16873071 20390343 19189210 18425577 19011961 18997820 19410462 17261762 18815881 18984771 17893378 17242785 18855134 19288272 19221464 19289846 15668708 19142967 11161223 20065188 19155303 16202921 17049068 16273361 20135344 20859285 15565566 19244106 20544844 18629630 21138602 19066611 19084267 20005174 19487384 19059307 19189212 19200415 17440819 18821012 18351453 19103187 19115204 21152245
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8020435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.3611589617
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5519066611
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.573084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 4.5716217749 15073043 15553829 14691202 11135700
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 4.5716924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.9419014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.1412490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0620419170
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6417572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 18670907 16120746
MESH:D002375 Catalepsy Haloperidol 4.961977408 15215559
MESH:D002386 Cataract Acetaminophen 2.6010977129
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.7220734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.8111677210 16105132 15861022 17681005 17110522 16919318 17333356
MESH:D002779 Cholestasis pirinixic acid 7.8119176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1116354765 15668235 8697196 15340226 12621046
MESH:D003072 Cognition Disorders Clozapine 5.0117123785
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 4.2212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7810525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7815322242 10048152 20055451
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.788888407 16575769 17688650
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 11.0315213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 11.0320210726
MESH:D003704 Dementia Haloperidol 4.6111575062
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4019031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 4.5316402076
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.5317107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5019279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.6215331141
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.1917906064 14550746 14725611 16485898 12705907 19923254 11739529 12594235 15968718 19420014 19085960 19164858 11743745 12153990 16081117 2444490 18713872 11421492 18071297 12392966 14986274 10663392 11461765 11529661 10915739 12540782 19416960 19370779 19739265 15619225 11287661 17522070 16177239 16393943 16109766 10774834 11834606 17562736 12958197 16781746 16227642
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.1920420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 6.191733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D050171 Dyslipidemias Clozapine 4.2016402076
MESH:D004421 Dystonia Valproic Acid 4.081851702
MESH:D004487 Edema pirinixic acid 6.6312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.6311000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9616714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.0712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.0719031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0616202921 19155303 20544844 17893378
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0510568697 9294722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.193659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.9816628512 3922381
MESH:D004827 Epilepsy Valproic Acid 2.9518234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.617562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.347750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.113659116
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.4612903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.4616530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver arsenic trioxide 24.9915073043
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.9915345470
MESH:D005234 Fatty Liver pirinixic acid 24.9919236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 24.9914986274 19224547
MESH:D005234 Fatty Liver Valproic Acid 24.9919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005315 Fetal Diseases Valproic Acid 4.9516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.178888407 18558336
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2319069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.9920067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.3016904648
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.4920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4911294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5520558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006529 Hepatomegaly pirinixic acid 8.4016221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.4015340226 12621046 16120746
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.8117440010
MESH:D006849 Hydrocephalus Valproic Acid 4.9217688650
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1115340226 18606429 8697196 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.7216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006948 Hyperkinesis Clozapine 4.9616046005
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9118670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Tamoxifen 4.9319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.9312200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.6516306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007674 Kidney Diseases Acetaminophen 2.2115629191 12587719
MESH:D007680 Kidney Neoplasms Tamoxifen 3.0718625569
MESH:D007938 Leukemia arsenic trioxide 2.8415070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.8217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.3616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.4514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.9217050201 16467208 20471514 16968895 19850784
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 3.9217596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.2316823087 12712474 9834237 11161223 19075265 19642359 11468182 17712046 15622746 15336539 16891316 16966277 17869043 17107899 15213294 12018890 12679006 15748426 17649720 16331271 19035177 16330433 16112521 17217047 19225113
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.3916882451
MESH:D008064 Lipidoses Clozapine 8.1517567588
MESH:D008064 Lipidoses Tamoxifen 8.1517567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.4018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4012878042
MESH:D008107 Liver Diseases Acetaminophen 1.6319784758 16611625 16610002 19460945 19014921 12587719 12969438 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2616871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 14.3414682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.3420195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 14.3420007298 15890375 16377806
MESH:D008113 Liver Neoplasms Tamoxifen 14.3416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.3416984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 5.8620377131
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.8612151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3715213294
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.3217228818
MESH:D008175 Lung Neoplasms arsenic trioxide 4.8519825857 11798837
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.8518520028 20464547 20869020 18569708 20064080 18816296 17053015 20135361 6695378
MESH:D008175 Lung Neoplasms Tamoxifen 4.8518625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8511884234 19555203
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8119428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.6411731420 19196723 14580682 16827153 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.6119453300
MESH:D008545 Melanoma Tamoxifen 1.8812393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6119513568
MESH:D001523 Mental Disorders Clozapine 8.5316856516
MESH:D001523 Mental Disorders Haloperidol 8.5316856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.4319142101
MESH:D008881 Migraine Disorders Valproic Acid 3.2118765137 18803445
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2116381670
MESH:D009101 Multiple Myeloma arsenic trioxide 3.1219417148 14977855 15949261 19549372 11468182
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.068888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.7318349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.4716882451 16105982
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 7.4717596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9716411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.0016624393
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.5519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms Benzo(a)pyrene 4.8611141357
MESH:D009369 Neoplasms pirinixic acid 4.8617405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0619189210 19200415 19196722
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2514600291
MESH:D009436 Neural Tube Defects arsenic trioxide 7.3910525206
MESH:D009436 Neural Tube Defects Valproic Acid 7.398888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8918514411
MESH:D009765 Obesity Clozapine 4.7218515891 19142110
MESH:D009765 Obesity pirinixic acid 4.7220558911
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4116624393 19769630 12452020
MESH:D010146 Pain Acetaminophen 2.4116870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5315580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1919927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 9.6311399792 11222880 11896295 11118676
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 9.6320603192
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.5319131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.5317292933
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.5315067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.3615861022 16919318
MESH:D019310 Pseudolymphoma Valproic Acid 4.6012752131 11422049
MESH:D011595 Psychomotor Agitation Haloperidol 5.0011575062
MESH:D011618 Psychotic Disorders Clozapine 9.2215331141
MESH:D011618 Psychotic Disorders Haloperidol 9.2211575062
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.2119155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.0016646077
MESH:D012559 Schizophrenia Clozapine 5.7411763009 20521320 17726453 18806925 20452607 17123785 20168265 17667964 20580759 16141801 20107430 19369910 18855531 11151749 20521326
MESH:D012559 Schizophrenia Haloperidol 5.741830565 20107430 19369910 18513383
MESH:D012559 Schizophrenia Valproic Acid 5.7415737665 19110320
MESH:D012640 Seizures Valproic Acid 2.751511512 16876388 3137016 15475178 11044598 11738929 14763951 17978042
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5119755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7716709447
MESH:D013088 Spermatocele Tamoxifen 11.7716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0919457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.8019490988
MESH:D013226 Status Epilepticus Valproic Acid 4.6012833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.3717007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.3720155912 2093021
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.7420210726
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.1119014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.0115213294
MESH:D014178 Translocation, Genetic Valproic Acid 5.3017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.573119515
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.3612845720 11780464 20435036 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.3617053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.3617572228 16712894 8653321
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.688888407
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5715869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D015430 Weight Gain Clozapine 4.4916402076 20107430 20521320 17502770 20564506 16141801
MESH:D015431 Weight Loss Clozapine 5.1317933447
Pathway ID Pathway Name
KEGG:04010 MAPK signaling pathway
REACT:498 Signaling by Insulin receptor
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33603
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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