Annotation Detail for TRMT12
Basic Information Top
| Gene Symbol: | TRMT12 ( FLJ20772,TRM12,TYW2 ) |
|---|---|
| Gene Full Name: | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| Band: | 8q24.13 |
| Quick Links | Entrez ID:55039; OMIM: 611244; Uniprot ID:TYW2_HUMAN; ENSEMBL ID: ENSG00000183665; HGNC ID: 26091 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D012402 | Rotenone | Rotenone results in decreased expression of TRMT12 mRNA | decreases expression | 19013527 |
| D014810 | Vitamin E | Vitamin E results in increased expression of TRMT12 mRNA | increases expression | 19244175 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D002252 | Carbon Tetrachloride Poisoning | Vitamin E | 4.69 | 16050911 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin E | 1.93 | 19769572 | |
| MESH:C538011 | Eales disease | Vitamin E | 5.77 | 9068938 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin E | 3.20 | 16080930 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin E | 2.83 | 16863852 16490937 | |
| MESH:D019584 | Hot Flashes | Vitamin E | 5.04 | 14716179 | |
| MESH:D007251 | Influenza, Human | Vitamin E | 5.28 | 16624496 | |
| MESH:D007674 | Kidney Diseases | Vitamin E | 3.05 | 12488133 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin E | 1.91 | 16169303 | |
| MESH:D008171 | Lung Diseases | Vitamin E | 3.48 | 16863852 | |
| MESH:D008175 | Lung Neoplasms | Vitamin E | 1.90 | 11062179 | |
| MESH:D009410 | Nerve Degeneration | Rotenone | 4.26 | 18619942 17356569 15790535 | |
| MESH:D010300 | Parkinson Disease | Rotenone | 3.11 | 19232380 19114014 16412576 18191903 18619942 16140633 11445065 15451049 11535288 | |
| MESH:D020734 | Parkinsonian Disorders | Rotenone | 4.58 | 15795934 18197244 15574749 15927086 | |
| MESH:D011471 | Prostatic Neoplasms | Vitamin E | 3.23 | 15084515 | |
| MESH:D012871 | Skin Diseases | Vitamin E | 2.53 | 18709164 | |
| MESH:D020521 | Stroke | Vitamin E | 3.93 | 16517955 |
| No data |