AutismKB 2.0

Annotation Detail for AIM1L


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Basic Information Top
Gene Symbol:AIM1L ( CRYBG2,DKFZp434L1713,FLJ10040,FLJ38020 )
Gene Full Name: absent in melanoma 1-like
Band: 1p36.11
Quick LinksEntrez ID:55057; OMIM: NA; Uniprot ID:AIM1L_HUMAN; ENSEMBL ID: ENSG00000176092; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of AIM1L mRNAincreases expression 20064835
D016572 Cyclosporine Cyclosporine results in increased expression of AIM1L mRNAincreases expression 20106945
D011374 Progesterone Progesterone results in increased expression of AIM1L mRNAincreases expression 17404688
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of AIM1L mRNAaffects cotreatment|increases expression 19244175
D012643 Selenium Selenium results in increased expression of AIM1L mRNAincreases expression 19244175
C024746 tobacco tar tobacco tar results in decreased expression of AIM1L mRNAdecreases expression 19559774
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of AIM1L mRNAaffects cotreatment|increases expression 19244175
D014810 Vitamin E Vitamin E results in increased expression of AIM1L mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.826695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.8617868700
MESH:D001930 Brain Injuries Progesterone 4.6815845082 15380490 15665606
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.1420146248 17474063
MESH:D001943 Breast Neoplasms Progesterone 2.1416175315 15562024 17614352
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.3516050911
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.7112371664
MESH:D002471 Cell Transformation, Neoplastic tobacco tar 7.7119559774
MESH:D002779 Cholestasis Cyclosporine 3.1419486331
MESH:D003092 Colitis Selenium 4.2017936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003929 Diabetic Neuropathies Progesterone 4.9117187935
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2415131321
MESH:C538011 Eales disease Vitamin E 5.229068938
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.1617692515
MESH:D004715 Endometriosis Progesterone 4.0716134523
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Cyclosporine 3.1819224547
MESH:D005355 Fibrosis Cyclosporine 3.5612168785 12639820
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 7.1820471113
MESH:D006330 Heart Defects, Congenital Vitamin E 7.1816080930
MESH:D006333 Heart Failure Selenium 3.2517162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7916863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.4914716179
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.8215869954
MESH:D007249 Inflammation Progesterone 2.7415869954
MESH:D007251 Influenza, Human Selenium 12.7616624496
MESH:D007251 Influenza, Human Vitamin E 12.7616624496
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Cyclosporine 6.5718776723 10903974 8314463
MESH:D007674 Kidney Diseases Vitamin E 6.5712488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.2116518626
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0012371664
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1321137059 20195826
MESH:D008171 Lung Diseases Vitamin E 3.3716863852
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.5020064080 18569708 20869020 18816296 17053015 6695378 18520028 20135361 20464547
MESH:D008175 Lung Neoplasms Vitamin E 2.5011062179
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.7711408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.7715318939
MESH:D008654 Mesothelioma Selenium 2.8915107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5718481113 19348381
MESH:D010051 Ovarian Neoplasms Progesterone 2.6017393432 16525653
MESH:D010954 Plasmacytoma Selenium 5.4115087411
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1217292933
MESH:D011471 Prostatic Neoplasms Vitamin E 3.1215084515
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9418045962
MESH:D012871 Skin Diseases Vitamin E 2.5018709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4919755658 10029692
MESH:D013119 Spinal Cord Injuries Progesterone 4.7415862959 16503802
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D020521 Stroke Vitamin E 3.7716517955
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2817053015
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018