Annotation Detail for PPP1R3A
Basic Information Top
| Gene Symbol: | PPP1R3A ( GM,PP1G,PPP1R3 ) |
|---|---|
| Gene Full Name: | protein phosphatase 1, regulatory (inhibitor) subunit 3A |
| Band: | 7q31.1 |
| Quick Links | Entrez ID:5506; OMIM: 600917; Uniprot ID:PPR3A_HUMAN; ENSEMBL ID: ENSG00000154415; HGNC ID: 9291 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| hsa04910 | Insulin signaling pathway |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 200168 | Insulin-mediated glucose transport |
| No data |
| No data |
| No data |
| No data |
| Desease Name |
|---|
| diabetes |
| polycystic ovary syndrome |
| METABOLIC |
| diabetes, type 2 |
| No data |
| Desease Name |
|---|
| Insulin resistance, severe, digenic |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of PPP1R3A mRNA | affects expression | 17562736 |
| C006780 | bisphenol A | bisphenol A results in decreased expression of PPP1R3A mRNA | decreases expression | 17706920 |
| C006780 | bisphenol A | LHB protein affects the reaction [bisphenol A results in decreased expression of PPP1R3A mRNA] | affects reaction|decreases expression | 17706920 |
| C004648 | testosterone enanthate | testosterone enanthate affects the expression of PPP1R3A mRNA | affects expression | 17440010 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001862 | Bone Resorption | bisphenol A | 4.35 | 11985600 | |
| MESH:D001943 | Breast Neoplasms | bisphenol A | 2.42 | 17123778 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002278 | Carcinoma in Situ | bisphenol A | 5.73 | 17123778 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19923254 11834606 10663392 19085960 19420014 11461765 12594235 17906064 15619225 16227642 11529661 19416960 19370779 16781746 17522070 14725611 12392966 11739529 11421492 14986274 16485898 16177239 10774834 18071297 2444490 16081117 14550746 10915739 19164858 11743745 12153990 12958197 16393943 18713872 17562736 11287661 12540782 19739265 16109766 15968718 12705907 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D019247 | HIV Wasting Syndrome | testosterone enanthate | 6.61 | 17440010 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D007333 | Insulin Resistance | bisphenol A | 3.56 | 16393666 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D052496 | Lipodystrophy, Familial Partial | marker/mechanism | |||
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16611625 19784758 16610002 19014921 12969438 19460945 11587558 12587719 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 16871587 17185352 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D009421 | Nervous System Malformations | bisphenol A | 4.56 | 11399458 16427766 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D010049 | Ovarian Diseases | bisphenol A | 5.73 | 11985600 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 4.69 | 10548101 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 4.69 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | bisphenol A | 3.34 | 16740699 | |
| MESH:D011629 | Puberty, Precocious | bisphenol A | 5.53 | 10548101 | |
| MESH:D019966 | Substance-Related Disorders | bisphenol A | 4.72 | 16684133 16045194 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 | |
| MESH:D014591 | Uterine Diseases | bisphenol A | 5.88 | 14652134 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04910 | Insulin signaling pathway |
Drug Bank