AutismKB 2.0

Annotation Detail for ARGLU1


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Basic Information Top
Gene Symbol:ARGLU1 ( DKFZp686O08106,FLJ10154 )
Gene Full Name: arginine and glutamate rich 1
Band: 13q33.3
Quick LinksEntrez ID:55082; OMIM: NA; Uniprot ID:ARGL1_HUMAN; ENSEMBL ID: ENSG00000134884; HGNC ID: 25482
Relate to Another Database: SFARIGene; denovo-db
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D013467 Sulindac Sulindac results in increased expression of ARGLU1 mRNAincreases expression 11906190
D019772 Topotecan ARGLU1 protein affects the susceptibility to Topotecanaffects response to substance 16217747
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Sulindac 6.5714745880
MESH:D058186 Acute Kidney Injury Sulindac 4.867897758
MESH:D000230 Adenocarcinoma Sulindac 3.2011910360
MESH:D000236 Adenoma Sulindac 4.0310223192
MESH:D011125 Adenomatous Polyposis Coli Sulindac 5.1019003578 16460482 12394442 11874996 11535846 15623613 17611924
MESH:D001913 Bowen's Disease Sulindac 6.4211207687
MESH:D001943 Breast Neoplasms Sulindac 3.1116642371
MESH:D003110 Colonic Neoplasms Sulindac 2.9812458338 12902858
MESH:D015179 Colorectal Neoplasms Sulindac 2.6910666051 11076880 18059344 11197048
MESH:D003930 Diabetic Retinopathy Sulindac 5.8512861449 17621415
MESH:D004715 Endometriosis Sulindac 4.9815652904
MESH:D004938 Esophageal Neoplasms Sulindac 3.2212235107
MESH:D018221 Fibromatosis, Abdominal Sulindac 6.3614745880
MESH:D018222 Fibromatosis, Aggressive Sulindac 6.0219069698
MESH:D005764 Gastroesophageal Reflux Sulindac 5.6911910360
MESH:D007249 Inflammation Sulindac 3.523291741
MESH:D007414 Intestinal Neoplasms Sulindac 5.1410223192 12628509 12351151 12663524 12584176 10213222
MESH:D007417 Intestinal Polyps Sulindac 5.5911245490 12394442
MESH:D008105 Liver Cirrhosis, Biliary Sulindac 4.5012468960
MESH:D008107 Liver Diseases Sulindac 3.1114986274 16867024
MESH:D008175 Lung Neoplasms Sulindac 2.7019359593 15713900
MESH:D008545 Melanoma Sulindac 2.8816642371
MESH:D009447 Neuroblastoma Topotecan 4.0615176712
MESH:D019636 Neurodegenerative Diseases Sulindac 4.7017266991 16850258
MESH:D010146 Pain Sulindac 4.223291741
MESH:D010190 Pancreatic Neoplasms Sulindac 3.4811504793 16820089
MESH:D014594 Uterine Neoplasms Sulindac 5.2718645019
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018