AutismKB 2.0

Annotation Detail for KIF26B


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Basic Information Top
Gene Symbol:KIF26B ( FLJ10157,MGC35030 )
Gene Full Name: kinesin family member 26B
Band: 1q44
Quick LinksEntrez ID:55083; OMIM: NA; Uniprot ID:KI26B_HUMAN; ENSEMBL ID: ENSG00000162849; HGNC ID: 25484
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of KIF26B mRNAincreases expression 19933214
D000082 Acetaminophen Acetaminophen affects the expression of KIF26B mRNAaffects expression 17562736
D001104 Arbutin Arbutin results in decreased expression of KIF26B mRNAdecreases expression 17103032
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of KIF26B mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of KIF26B mRNAincreases expression 19482888
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of KIF26B mRNAincreases expression 19933214
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 10.156195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.1515322242 14514962 11752688
MESH:D018248 Adenoma, Liver Cell Phenobarbital 11.9517620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 11.9516835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.2911748828
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.4212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.4015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9715746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.6720435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 3.0916835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.013084413
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 3.0120935162 17173139 1701930 20007298 6705139
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5418670907 18850075 16120746
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.744080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4916835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.2215668235 8697196 16354765 15340226 12621046
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3814669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2710048152 20055451 15322242
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7317107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.8318071297 16485898 11834606 15619225 19416960 10774834 16227642 19420014 17906064 11529661 16177239 11421492 11461765 12153990 12958197 14550746 16081117 19164858 12705907 11739529 14725611 12392966 19085960 17562736 15968718 12594235 16781746 16393943 11287661 19923254 18713872 2444490 19739265 19370779 16109766 12540782 10915739 10663392 14986274 17522070 11743745
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.8320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0211462148
MESH:D004421 Dystonia Phenobarbital 4.411851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.7411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.5118230668 15322242 16714409
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.3710568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.593659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.483922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.876401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.563659116
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2711564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.9411858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.4320067830
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.2110696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4910048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.7111000095
MESH:D006529 Hepatomegaly Phenobarbital 10.1016109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.1016120746 15340226 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.668697196 18606429 15340226 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0118670907 18850075
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0112200463 12878042
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.7116580747
MESH:D007674 Kidney Diseases Acetaminophen 2.3815629191 12587719
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0721047994
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008107 Liver Diseases Acetaminophen 4.1716610002 12587719 19784758 16611625 19460945 11587558 19014921 12969438
MESH:D008107 Liver Diseases Phenobarbital 4.1719363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008113 Liver Neoplasms Phenobarbital 4.7919482888 21047994 19812893 15975961 8742319 19073162
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.7916984957
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 6.481399818 2563599 17172636 18308698 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.4812151625
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 1.2411884234 19555203
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3112213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.0217484760
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.6514600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D010018 Osteomalacia Phenobarbital 4.9017016548
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5916965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.8612520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.0018163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.952563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.7311896295 11118676 11399792 11222880
MESH:D019310 Pseudolymphoma Phenobarbital 5.1112752131
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.2818990726
MESH:D012640 Seizures Phenobarbital 2.9216876388 3137016 11442880 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.366407741
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1816192470
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.5112697716
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.321399818
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.2112125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.8615886252
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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