AutismKB 2.0

Annotation Detail for SOBP


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Basic Information Top
Gene Symbol:SOBP ( FLJ10159,JXC1 )
Gene Full Name: sine oculis binding protein homolog (Drosophila)
Band: 6q21
Quick LinksEntrez ID:55084; OMIM: NA; Uniprot ID:SOBP_HUMAN; ENSEMBL ID: ENSG00000112320; HGNC ID: 29256
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of SOBP mRNAdecreases expression 15336504
D012643 Selenium Selenium results in decreased expression of SOBP mRNAdecreases expression 19244175
D014635 Valproic Acid Valproic Acid results in increased expression of SOBP mRNAincreases expression 19101580
D014810 Vitamin E Vitamin E results in decreased expression of SOBP mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.118875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3519490988
MESH:D000550 Amblyopia Valproic Acid 5.9617688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.9017497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9818396377 17688650 18775368 17157402 18177632 17507914 18985861 18316065 16609825 20603192 18558336 15238991 18940202 19232924 19460635
MESH:D001714 Bipolar Disorder Valproic Acid 3.2417594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.638888407
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4916050911
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8220734317
MESH:D003092 Colitis Selenium 4.3417936198
MESH:D019465 Craniofacial Abnormalities Valproic Acid 2.8017688650 8888407 16575769
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.8019769572
MESH:D056486 Drug-Induced Liver Injury Selenium 4.3115131321
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.311733752 19641884
MESH:D004421 Dystonia Valproic Acid 4.511851702
MESH:C538011 Eales disease Vitamin E 5.439068938
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.7117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.643922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1120417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.966254150 6426943 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.867750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.693659116
MESH:D005234 Fatty Liver Valproic Acid 3.7219224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.6116575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.648888407 18558336
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1716080930
MESH:D006333 Heart Failure Selenium 3.2917162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8116863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.6914716179
MESH:D006849 Hydrocephalus Valproic Acid 5.5017688650
MESH:D007251 Influenza, Human Selenium 13.5016624496
MESH:D007251 Influenza, Human Vitamin E 13.5016624496
MESH:D007674 Kidney Diseases Vitamin E 3.0012488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.3116518626
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9116169303
MESH:D008171 Lung Diseases Vitamin E 3.4316863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.9817228818
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9915318939
MESH:D008654 Mesothelioma Selenium 2.9215107826
MESH:D008881 Migraine Disorders Valproic Acid 3.4718765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.458888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3517596541
MESH:D009436 Neural Tube Defects Valproic Acid 3.3716359493 8888407
MESH:D010954 Plasmacytoma Selenium 5.6115087411
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.4620603192
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2415084515
MESH:D019310 Pseudolymphoma Valproic Acid 5.2612752131 11422049
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.6419155313
MESH:D012559 Schizophrenia Valproic Acid 2.1019110320 15737665
MESH:D012640 Seizures Valproic Acid 2.9915475178 16876388 3137016 11738929 1511512 17978042 14763951 11044598
MESH:D012871 Skin Diseases Vitamin E 2.5218709164
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.848532709
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0919490988
MESH:D013226 Status Epilepticus Valproic Acid 5.2612833885
MESH:D020521 Stroke Vitamin E 3.8416517955
MESH:D014178 Translocation, Genetic Valproic Acid 5.9617262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.153119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.208888407
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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