AutismKB 2.0

Annotation Detail for ATG2B


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Basic Information Top
Gene Symbol:ATG2B ( C14orf103,FLJ10242 )
Gene Full Name: ATG2 autophagy related 2 homolog B (S. cerevisiae)
Band: 14q32.2
Quick LinksEntrez ID:55102; OMIM: NA; Uniprot ID:ATG2B_HUMAN; ENSEMBL ID: ENSG00000066739; HGNC ID: 20187
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ATG2B mRNAaffects expression 17555576
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ATG2B mRNAaffects binding|increases activity|increases expression 19710929
D011374 Progesterone Progesterone results in increased expression of ATG2B mRNAincreases expression 18070364
D013629 Tamoxifen Tamoxifen affects the expression of ATG2B mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.2714745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 6.0617868700
MESH:D001930 Brain Injuries Progesterone 4.8215380490 15845082 15665606
MESH:D001943 Breast Neoplasms Progesterone 2.2016175315 15562024 17614352
MESH:D001943 Breast Neoplasms Tamoxifen 2.2020065188 20859285 19244106 18815881 19142967 21138602 18629630 19410462 18997820 17893378 19066611 19189210 19103187 17440819 16818667 16873071 18425577 17242785 18821012 16273361 19289846 19011961 18984771 19200415 20005174 21152245 18855134 19487384 16202921 19084267 15565566 19189212 19115204 17049068 11161223 19059307 18351453 17261762 19221464 20390343 19155303 19288272 20544844 20135344 15668708
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 5.0719066611
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 1.8616924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 4.0117572228
MESH:D002779 Cholestasis Ethinyl Estradiol 8.7317681005 11677210 17333356 16105132 17110522 15861022 16919318
MESH:D002779 Cholestasis pirinixic acid 8.7319176532
MESH:D003711 Demyelinating Diseases Tamoxifen 4.9219031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.8419279558
MESH:D003929 Diabetic Neuropathies Progesterone 5.0517187935
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 18.4812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 18.4817692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 18.4819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2919155303 17893378 20544844 16202921
MESH:D004715 Endometriosis Progesterone 4.1616134523
MESH:D005234 Fatty Liver Ethinyl Estradiol 15.6415345470
MESH:D005234 Fatty Liver pirinixic acid 15.6419236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 15.6419224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4516709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 5.1614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.8119069698
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006529 Hepatomegaly pirinixic acid 3.5518467677 16221962 19772884 19176532
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 4.9615869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007249 Inflammation Progesterone 5.7615869954
MESH:D007249 Inflammation Tamoxifen 5.7619457130
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007680 Kidney Neoplasms Tamoxifen 3.3818625569
MESH:D008064 Lipidoses Tamoxifen 3.4315342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4115474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.4118564211
MESH:D008113 Liver Neoplasms pirinixic acid 4.8416377806 20007298 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 4.8416684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 6.8811408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.8819196723 14580682 16827153 11731420 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 5.2719453300
MESH:D008545 Melanoma Tamoxifen 1.9219393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.8115990972
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6719393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6119410462
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.7219189210 19200415 19196722
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010051 Ovarian Neoplasms Progesterone 2.6217393432 16525653
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.0915067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9618045962
MESH:D013088 Spermatocele Ethinyl Estradiol 14.1116709447
MESH:D013088 Spermatocele Tamoxifen 14.1116709447
MESH:D013119 Spinal Cord Injuries Progesterone 13.0716503802 15862959
MESH:D013119 Spinal Cord Injuries Tamoxifen 13.0719457130
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.488653321 16712894 17572228
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9714671159 15869587
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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