AutismKB 2.0

Annotation Detail for WDR60


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Basic Information Top
Gene Symbol:WDR60 ( FLJ10300,FLJ23575 )
Gene Full Name: WD repeat domain 60
Band: 7q36.3
Quick LinksEntrez ID:55112; OMIM: NA; Uniprot ID:WDR60_HUMAN; ENSEMBL ID: ENSG00000126870; HGNC ID: 21862
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of WDR60 mRNAincreases expression 20406850
D000082 Acetaminophen Acetaminophen affects the expression of WDR60 mRNAaffects expression 17562736
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of WDR60 mRNAaffects expression 17555576
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.8117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8914692618
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.9115885639
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 2.9716705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.973084413
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.066135515
MESH:D002779 Cholestasis Ethinyl Estradiol 3.2017333356 11677210 16105132 17110522 15861022 16919318 17681005
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.6718551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 4.0521346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0515968718 11461765 14986274 18713872 16109766 12705907 19085960 10774834 11421492 14725611 11834606 10663392 16393943 12958197 16177239 16781746 19370779 19923254 19164858 18071297 17522070 2444490 17562736 11529661 16485898 10915739 16081117 12153990 16227642 14550746 12594235 19416960 15619225 12540782 19420014 11739529 11287661 19739265 11743745 12392966 17906064
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.7712538720
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.2915345470
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007021 Hypospadias Ethinyl Estradiol 4.4616569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7617937319
MESH:D007674 Kidney Diseases Acetaminophen 2.4212587719 15629191
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.3616705839
MESH:D008107 Liver Diseases Acetaminophen 1.7112969438 16610002 19784758 19460945 12587719 16611625 11587558 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.287678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.796135515 2876784 2876786
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.6018551238 7678174
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8816049721
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.2211578682
MESH:D011537 Pruritus Ethinyl Estradiol 4.0516919318 15861022
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8218551238
MESH:D013088 Spermatocele Ethinyl Estradiol 4.8116709447
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.1511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5715669648
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.0610091137
MESH:D014581 Urticaria Acetaminophen 3.5010982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8814692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 4.0214671159 15869587
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018