AutismKB 2.0

Annotation Detail for CEP192


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Basic Information Top
Gene Symbol:CEP192 ( - )
Gene Full Name: centrosomal protein 192kDa
Band: 18p11.21
Quick LinksEntrez ID:55125; OMIM: NA; Uniprot ID:B7ZMF0_HUMAN; ENSEMBL ID: ENSG00000101639; HGNC ID: 25515
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CEP192 mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CEP192 mRNAdecreases expression 20106945
20064835
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of CEP192 mRNAdecreases expression 15336504
C051890 irinotecan irinotecan analog results in decreased expression of CEP192 mRNAdecreases expression 18927307
C011890 kojic acid kojic acid results in increased expression of CEP192 mRNAincreases expression 16595896
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D003110 Colonic Neoplasms irinotecan 2.6417725105 17287894
MESH:D015179 Colorectal Neoplasms irinotecan 2.3617159606 16391804 18259882 18509181 16303861 17454858 15273666
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6619370779 12705907 17562736 15968718 16177239 12958197 16485898 16781746 12392966 14725611 19085960 11421492 16109766 17522070 11834606 19416960 10774834 11461765 16393943 18071297 14986274 19164858 16227642 11287661 16081117 10915739 15619225 11529661 14550746 18713872 12594235 11739529 12540782 10663392 12153990 11743745 19739265 19420014 2444490 19923254 17906064
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.6919460945 11587558 19014921 16611625 12969438 19784758 12587719 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1420195826 21137059
MESH:D008114 Liver Neoplasms, Experimental kojic acid 3.5318544905
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5718816296 20464547 18569708 20064080 6695378 18520028 17053015 20869020 20135361
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D052016 Mucositis irinotecan 5.5517159606
MESH:D009362 Neoplasm Metastasis irinotecan 3.2818259882
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D009447 Neuroblastoma irinotecan 3.648761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D017599 Neuroectodermal Tumors irinotecan 5.278761367
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 6.1919755658 10029692
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.198532709
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.622093021 20155912
MESH:D013274 Stomach Neoplasms irinotecan 2.6215723263
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018