Annotation Detail for RBM28
Basic Information
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| Desease Name |
|---|
| Alopecia, neurologic defects, and endocrinopathy syndrome |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of RBM28 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of RBM28 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of RBM28 mRNA | affects expression | 17562736
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of RBM28 mRNA | increases expression | 20106945
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| OMIM:612079 |
ALOPECIA, NEUROLOGIC DEFECTS, AND ENDOCRINOPATHY SYNDROME |
marker/mechanism |
|
| |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.57 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.78 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.78 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
4.78 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.79 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
7.46 | 6135515 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
7.46 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.21 | 19486331 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.83 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.83 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.72 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.72 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.72 | 2444490 14725611 12540782 17522070 19923254 11461765 18713872 16781746 16393943 11421492 16177239 18071297 19085960 11287661 17562736 10915739 19420014 10663392 14986274 12705907 19164858 16227642 12392966 19416960 19370779 12958197 15968718 11834606 10774834 17906064 16109766 12153990 14550746 19739265 16081117 15619225 12594235 16485898 11529661 11739529 11743745 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.82 | 19426721 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.28 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.70 | 12168785 12639820 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.40 | 16983495 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.85 | 8708960 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.05 | 15720958 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.02 | 16870215 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.21 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.16 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.48 | 15629191 12587719 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
6.48 | 18776723 10903974 8314463 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
14.44 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
14.44 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
14.44 | 12371664 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.70 | 12587719 16610002 19014921 16611625 12969438 19460945 19784758 11587558 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.63 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.27 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.77 | 6135515 2876784 2876786 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.13 | 19513568 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.51 | 16801185 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.54 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
12.54 | 18551238 7678174 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.16 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.65 | 18481113 19348381 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.21 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.23 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.23 | 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.73 | 16870215 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.59 | 12371664 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.33 | 16882103 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.74 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.74 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.43 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.43 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
14.19 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
14.19 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.44 | 10982225 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.71 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.16 | 17120751 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:03008 |
Ribosome biogenesis in eukaryotes |
Related Pathway Information