AutismKB 2.0

Annotation Detail for ANKZF1


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Basic Information Top
Gene Symbol:ANKZF1 ( FLJ10415,FLJ13144,ZNF744 )
Gene Full Name: ankyrin repeat and zinc finger domain containing 1
Band: 2q35
Quick LinksEntrez ID:55139; OMIM: NA; Uniprot ID:ANKZ1_HUMAN; ENSEMBL ID: ENSG00000163516; HGNC ID: 25527
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ANKZF1 mRNAaffects expression 17562736
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of ANKZF1 mRNAincreases expression 17484886
D003474 Curcumin Curcumin results in decreased expression of ANKZF1 mRNAdecreases expression 17198877
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D019973 Alcohol-Related Disorders Curcumin 5.9517887948
MESH:D000544 Alzheimer Disease Curcumin 2.6915590663
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.8116807698
MESH:D050197 Atherosclerosis Curcumin 3.5518704882
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001327 Autoimmune Diseases Curcumin 5.1419761891
MESH:D002545 Brain Ischemia Curcumin 5.0716770732
MESH:D001932 Brain Neoplasms Curcumin 4.3817596214
MESH:D001943 Breast Neoplasms Curcumin 2.7019250217 18462866 16243823 18593918
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.4315673190 10355542 16050911 16124888 16192424 16097048 16227642 16011737 15721981 3786805 15700767 18705752
MESH:D002277 Carcinoma Curcumin 4.2018593918
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.003084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 3.0018788625
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 3.0918414057
MESH:D002294 Carcinoma, Squamous Cell Curcumin 2.8518462866
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D003092 Colitis Curcumin 4.8316804969 16782535 18200517
MESH:D003103 Coloboma Curcumin 5.0318809619
MESH:D003110 Colonic Neoplasms Curcumin 2.5619359593 16340194
MESH:D016510 Corneal Neovascularization Curcumin 5.5518497527
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 2.7818403477
MESH:D003928 Diabetic Nephropathies Curcumin 4.4318204486
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.082444490 16109766 10663392 18071297 19420014 16081117 16227642 19739265 17522070 11287661 12594235 12705907 14986274 10915739 15619225 16177239 10774834 19085960 19164858 15968718 11834606 17906064 11421492 11461765 19370779 12540782 16485898 11739529 12958197 14725611 16393943 11743745 19923254 12153990 11529661 18713872 12392966 19416960 17562736 16781746 14550746
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.087179309 15968718 3732212 3786805 6884620 11566570 10092053 4309450 10915739 15998439 21278145 17522070 15027814 6623471 7440962 7120509 2869522 19336974 19085960 9327722 16227642 16177239
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004381 Duodenal Ulcer Curcumin 4.6317351913
MESH:D005234 Fatty Liver Carbon Tetrachloride 9.6715959796 12631006 16239168 19224547 17595544 61145 12795759 16045604
MESH:D005234 Fatty Liver Curcumin 9.6719297423
MESH:D005355 Fibrosis Carbon Tetrachloride 11.2418705752
MESH:D005355 Fibrosis Curcumin 11.2418705752
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D005770 Gastrointestinal Neoplasms Curcumin 5.3518462866
MESH:D005909 Glioblastoma Curcumin 3.7417596214
MESH:D006258 Head and Neck Neoplasms Curcumin 3.9418462866 18829502
MESH:D006505 Hepatitis Carbon Tetrachloride 4.1819110552 19900420
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.6917701891
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.2716899240
MESH:D006937 Hypercholesterolemia Curcumin 4.5418704882
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.7415338365
MESH:D007249 Inflammation Curcumin 3.0816956363 17151092 18403477
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.3418596194 18200517
MESH:D007414 Intestinal Neoplasms Curcumin 4.6710783313
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D007889 Leiomyoma Curcumin 5.1018555241
MESH:D007938 Leukemia Curcumin 3.4218462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.6916106398
MESH:D015458 Leukemia, T-Cell Curcumin 5.3516106398
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0216221502 16943688 17174718 17157831 21278145 11903743 17334410 16239168 11408273
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.7615959796 15123356 15931870 11481614 12666154 18339082 18472094 18187930 16136751 18166357 16033810 15362042 12649538 18481824 15818738 18429990 18054572 16192424 17869086 12632512 18277467 17631135 15370692 16116963 17761835 18705752 16097048 15057751 14512876 17944888 14748882 18317297 18420326 17565644 16015684 15996030 15052691 15893842 17922224 15650968 18376398 17721639 17698563 12586293 18006644 16027843 17900296 10355542 17823541 12741479 16011737 14724832 14620537 18279442 18472332 17766677 12445418 20821823 14716496 18205269 12389079 12958196 15925388 12667390 18395095 12445421 17481882 13678700 14716833 18251166 12609069 17805973 16638106 18395914 17708605 15876570 17976157 15673190 18263696 15730626 18412020 17525996 17714472 17640975 18210741 12898905 18418968 16248980 18156304 15338365 12632514 12546737 17557913
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 2.7617355460 18705752 18006644
MESH:D008107 Liver Diseases Acetaminophen 7.0719784758 12969438 19014921 16611625 19460945 12587719 11587558 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 7.0715830285 15720792 17285989 16246199 16964402
MESH:D008107 Liver Diseases Curcumin 7.0716956363
MESH:D017093 Liver Failure Carbon Tetrachloride 4.8215123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.9416871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.9414706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3519294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8612014681 15583823
MESH:D008175 Lung Neoplasms Curcumin 2.2816243823 19359593 18462866
MESH:D008223 Lymphoma Curcumin 3.8918462866
MESH:D016399 Lymphoma, T-Cell Curcumin 5.3516173963
MESH:D008545 Melanoma Curcumin 2.4617885582 18462866
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D008569 Memory Disorders Curcumin 4.7417263510
MESH:D009101 Multiple Myeloma Curcumin 3.8219372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 5.6617962980
MESH:D009361 Neoplasm Invasiveness Curcumin 4.9518495463
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 5.4012497104
MESH:D009423 Nervous System Neoplasms Curcumin 6.5018462866
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D009765 Obesity Curcumin 2.8219297423
MESH:D010024 Osteoporosis Curcumin 3.7118719352
MESH:D010051 Ovarian Neoplasms Curcumin 2.9218462866 19020741
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D010190 Pancreatic Neoplasms Curcumin 3.0519196508 19401701 17440100
MESH:D011471 Prostatic Neoplasms Curcumin 3.6118156803 15129424 12497104 18226269 11398177 10851300 18769126
MESH:D011656 Pulmonary Emphysema Curcumin 4.9819168576
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 4.5518379247 10666014
MESH:D012509 Sarcoma Curcumin 4.5618462866
MESH:D018805 Sepsis Curcumin 4.4618389075
MESH:D013276 Stomach Ulcer Curcumin 3.9716631530 19188055
MESH:D001749 Urinary Bladder Neoplasms Curcumin 3.0218593936
MESH:D014565 Urogenital Neoplasms Curcumin 6.0118462866
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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