AutismKB 2.0

Annotation Detail for AVPR1A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:AVPR1A ( AVPR1 )
Gene Full Name: arginine vasopressin receptor 1A
Band: 12q14.2
Quick LinksEntrez ID:552; OMIM: 600821; Uniprot ID:V1AR_HUMAN; ENSEMBL ID: ENSG00000166148; HGNC ID: 895
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04270Vascular smooth muscle contraction
hsa04080Neuroactive ligand-receptor interaction
hsa04020Calcium signaling pathway
Pathway IDPathway Name
Signaling by GPCR
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1862Conduct disorder
1916Pervasive development disorder
2091Hypertension
2124Autistic disorder
Desease Name
PSYCH
musical aptitude
dance performance
Autism
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of AVPR1A mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of AVPR1A mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen results in decreased expression of AVPR1A mRNAdecreases expression 17202762
D000643 Ammonium Chloride Ammonium Chloride affects the expression of AVPR1A mRNAaffects expression 16483693
D000661 Amphetamine Amphetamine results in increased expression of AVPR1A proteinincreases expression 19858480
D001761 Bleomycin Bleomycin results in decreased expression of AVPR1A mRNAdecreases expression 15808516
D002330 Carmustine Carmustine results in increased expression of AVPR1A mRNAincreases expression 15980968
D002995 Clofibric Acid Clofibric Acid affects the expression of AVPR1A mRNAaffects expression 17602206
C030123 coumarin coumarin results in decreased expression of AVPR1A mRNAdecreases expression 18480146
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AVPR1A mRNA]decreases expression|decreases reaction 11007951
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of AVPR1A mRNAdecreases expression 19638242
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of AVPR1A mRNAincreases expression 15953391
17108234
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of AVPR1A geneincreases mutagenesis 16495775
D008997 Monobactams Monobactams analog binds to AVPR1A proteinaffects binding 16504276
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of AVPR1A mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of AVPR1A mRNAdecreases expression 19270015
D010634 Phenobarbital Phenobarbital results in increased expression of AVPR1A mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of AVPR1A mRNAaffects binding|decreases expression|increases activity 19710929
C006253 pirinixic acid pirinixic acid results in decreased expression of AVPR1A mRNAdecreases expression 17950772
C025299 polyphenols polyphenols results in decreased expression of AVPR1A mRNAdecreases expression 16293270
C082134 relcovaptan relcovaptan results in decreased activity of AVPR1A proteindecreases activity 15685210
C009250 sevoflurane sevoflurane affects the expression of AVPR1A mRNAaffects expression 15967596
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AVPR1A mRNA]decreases expression|decreases reaction 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of AVPR1A mRNAdecreases expression 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of AVPR1A mRNAincreases expression 16054898
D013853 Thioacetamide Thioacetamide results in decreased expression of AVPR1A mRNAdecreases expression 16337175
C052342 topiramate topiramate results in decreased expression of AVPR1A mRNAdecreases expression 16979414
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 7.936195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.9314514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.4518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8417505938
MESH:D055371 Acute Lung Injury Bleomycin 9.0117118201
MESH:D055371 Acute Lung Injury pirinixic acid 9.0118653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7914692618
MESH:D000236 Adenoma Diethylnitrosamine 6.8110737359 6695378
MESH:D000236 Adenoma Ethylnitrosourea 6.816695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 23.9719052882 16434500 17162532 19061943 18056438 17620307
MESH:D018248 Adenoma, Liver Cell Phenobarbital 23.9717620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 23.9716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 23.9716835633
MESH:D000437 Alcoholism topiramate 4.9418552399 17925516 19331489
MESH:D019969 Amphetamine-Related Disorders Amphetamine 5.9515010207 18475255 16916582 16459022
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8511748828
MESH:D000799 Angioedema Acetaminophen 3.7410982225
MESH:D000855 Anorexia Amphetamine 4.9116101753 12183048 16084549 12005258
MESH:D000860 Anoxia Bleomycin 5.3015782499
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6015885639
MESH:D001321 Autistic Disorder marker/mechanism 16520824
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 14.7619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 14.7612125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 14.7619483382
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6915746008
MESH:D001927 Brain Diseases Ethylnitrosourea 4.7814991843
MESH:D001932 Brain Neoplasms Carmustine 8.9816187019
MESH:D001932 Brain Neoplasms Ethylnitrosourea 8.9816357521 16651633 15144691 16436596 18412241
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9917474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9920435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7116835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.6816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.683084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.683084413 19171122 18393292 17138121 16807293 17055752 18785209 20514400 19052882 10672840 19335982 16502159 17428255 17173139 3581430 16288022 19701751 16878318 20524982 18506893 20084675 19919837 20007298 18788625 19394651 17978847 20935162 17761372 18210153 11831363 19519916 17162532 19539802 10737359 19822196 18494052 16328049 21159647 18978308 16681979 18691550 18665156 18971187 20101231 20727157 16830150 20512989 16779866 20432363 16540662 19418558 19383236 18056438 16698587 19208518 19107877 16935385 16569478 20214788
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 8.6820007298 1701930 20935162 17173139 6705139
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 8.6817997003
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 3.576189445
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3118670907 18850075 16120746
MESH:D002386 Cataract Acetaminophen 2.5210977129
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.792727394 21159647 17174075 7505956
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 6.7916003739
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.144080065
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 5.8817160924
MESH:D002659 Child Development Disorders, Pervasive marker/mechanism 20546835
MESH:D002659 Child Development Disorders, Pervasive topiramate 4.0615650499
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 15.5719052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 15.5716835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 15.5718291259
MESH:D002779 Cholestasis Ethinyl Estradiol 7.4717333356 16919318 17110522 17681005 15861022 11677210 16105132
MESH:D002779 Cholestasis pirinixic acid 7.4719176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0615668235 8697196 16354765 15340226 12621046
MESH:D003110 Colonic Neoplasms polyphenols 2.6616293270
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9617141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2520055451 15322242 10048152
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.9118551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3818249437
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 10.1219647726
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 10.1220387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 10.1217107852
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 10.1216979414
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 14.8421346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.8412594235 11461765 11743745 14725611 10774834 14986274 11739529 10915739 18713872 19739265 19420014 11834606 15619225 12705907 12392966 11287661 15968718 16227642 17562736 16781746 19164858 11529661 11421492 17906064 16109766 12958197 19923254 12153990 16393943 12540782 2444490 18071297 16485898 14550746 19085960 10663392 19370779 19416960 17522070 16177239 16081117
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.8419107877
MESH:D056486 Drug-Induced Liver Injury polyphenols 14.8419370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.8420420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 14.8412963478
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9919426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6811462148
MESH:D004421 Dystonia Phenobarbital 3.901851702
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 5.8818357618
MESH:D004487 Edema Bleomycin 10.9717118201
MESH:D004487 Edema pirinixic acid 10.9712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.9711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8018230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.0812538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9210568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.003659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.773922381 11558140
MESH:D004827 Epilepsy Phenobarbital 6.9920417680
MESH:D004827 Epilepsy topiramate 6.9919148780
MESH:D004832 Epilepsy, Absence Phenobarbital 3.456401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.147750514
MESH:D004833 Epilepsy, Temporal Lobe topiramate 6.1716499746
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.913659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0116302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9311564622
MESH:D005221 Fatigue Amphetamine 5.4919890266
MESH:D005218 Fat Necrosis Thioacetamide 5.6116456712
MESH:D005234 Fatty Liver Diethylnitrosamine 12.4520387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.4515345470
MESH:D005234 Fatty Liver pirinixic acid 12.4520131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3511858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.8420067830
MESH:D005756 Gastritis Acetaminophen 3.5716983495
MESH:D005909 Glioblastoma Carmustine 7.5216187019
MESH:D005909 Glioblastoma Ethylnitrosourea 7.5216436596
MESH:D005910 Glioma Ethylnitrosourea 3.4516357521 18412241 16651633
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4910696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2711294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.4720558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2311000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.4718665440 17276928 15929193
MESH:D006505 Hepatitis Thioacetamide 4.1116456712
MESH:D006529 Hepatomegaly Phenobarbital 13.7516109766
MESH:D006529 Hepatomegaly pirinixic acid 13.7518467677 19176532 19772884 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.7516120746 15340226 12621046
MESH:D006689 Hodgkin Disease Bleomycin 4.2817606976 15147373 18501091
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9418606429 16354765 15340226 16959395 8697196
MESH:D006930 Hyperalgesia Acetaminophen 2.6116870215
MESH:D006943 Hyperglycemia pirinixic acid 3.0820558911
MESH:D006948 Hyperkinesis Amphetamine 5.321977408 14960337
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8718850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7016945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3612013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4117937319
MESH:D007249 Inflammation Bleomycin 11.5717118201
MESH:D007249 Inflammation Diethylnitrosamine 11.5718785209
MESH:D007249 Inflammation polyphenols 11.5716366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.5712200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.5616306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2316580747
MESH:D007674 Kidney Diseases Acetaminophen 2.1415629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.4116705839
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 7.4117379185
MESH:D007859 Learning Disorders sevoflurane 4.6619212262
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4420032147 18665156 18407596 18522880 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 6.4421047994
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4015474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4012878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 3.4012679928 11682029 15316131 15474484 18032466 15078482 17629604 16126171 15334695 18031379 16098781 15716488 14739098 15095483 11481614 15158331 12531686 16248980 11172339 18458672 18295389 16097051 17050028 12891558 18416461 15288472 15288473 18380797 15075984 18395095 18606216 18615449 17292413 18263696 16343077 16489207 12557150 12175628 15362042 16511523 17355460 15465738 12085344 10677585 17127702
MESH:D008107 Liver Diseases Acetaminophen 12.2416611625 19784758 16610002 12969438 12587719 19014921 11587558 19460945
MESH:D008107 Liver Diseases Diethylnitrosamine 12.2417034775
MESH:D008107 Liver Diseases Phenobarbital 12.2419363144
MESH:D008107 Liver Diseases polyphenols 12.2416698588
MESH:D008107 Liver Diseases Thioacetamide 12.2418374380 15158337 16337175
MESH:D017114 Liver Failure, Acute Acetaminophen 9.3117185352 16871587
MESH:D017114 Liver Failure, Acute Thioacetamide 9.3115313186 17276928 12479984 15633222
MESH:D008113 Liver Neoplasms Clofibric Acid 13.8017602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.8015175105 9163691 21167192 10737359 18977376 19427195 20118626 18644402 19090486 19256749 19255062 21047994 19642983 20405173 20434301 19833225 21071580 19426721 20501860 18754104 20101389 20492335 19254457 16942905 19294768 12112319 2422723 19690152 19551842 19638242 19996281 20452335 19073162 19812893 19850985 20137499 18648771 12771043 15885732 19499222 20583210 21278145 2862719 18978307
MESH:D008113 Liver Neoplasms Phenobarbital 13.8019812893 8742319 19073162 19482888 15975961 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 13.8015890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.8016984957
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.4119126423 18079962 3124819 18544905 18093689 19539802 17942915 18775883 18253720 16267830 19004024 19009564 16842330 2563599 18282651 9362446 17854601 18164116 21159647 18308698 19519916 17174075
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 9.416150874 1399818 2563599 17172636 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.4112151625
MESH:D008175 Lung Neoplasms Bleomycin 4.836189445
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.8321163286 20512841 20970405 6695378
MESH:D008175 Lung Neoplasms Ethylnitrosourea 4.8316019985 16271038 6695378 17703301
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8311884234 19555203
MESH:D008223 Lymphoma Ethylnitrosourea 3.8615790496
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 4.9415375218
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 3.4418041768 10838139 10767621
MESH:D008545 Melanoma Bleomycin 4.0715577320
MESH:D008545 Melanoma Carmustine 4.0712393984
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4619513568
MESH:D008569 Memory Disorders sevoflurane 4.6419212262
MESH:D008579 Meningioma Ethylnitrosourea 5.8817943659
MESH:D008881 Migraine Disorders topiramate 4.5018759728 18803445 18765137 16942474
MESH:D009135 Muscular Diseases pirinixic acid 3.4016239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1019151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9312213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8616411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.3717484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.7518551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.523581430 9029167
MESH:D009369 Neoplasms pirinixic acid 1.9017405874
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 4.2916707424
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1114600291
MESH:D009442 Neurilemmoma Ethylnitrosourea 5.3117160924 16651423 16003739
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.6418514411
MESH:D019636 Neurodegenerative Diseases Amphetamine 13.6415183010
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.6420387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0120387270
MESH:D009765 Obesity pirinixic acid 1.7920558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.3312819281 16049721
MESH:D009837 Oligodendroglioma Ethylnitrosourea 5.8817160924
MESH:D010018 Osteomalacia Phenobarbital 4.2617016548
MESH:D010146 Pain Acetaminophen 2.3016870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.1316540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.1316965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5811578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1412520081
MESH:D011014 Pneumonia Bleomycin 5.3017071938 16317386 18024389
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4518163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.772563599
MESH:D011230 Precancerous Conditions Phenobarbital 8.772563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0811222880 11118676 11399792 11896295
MESH:D011537 Pruritus Ethinyl Estradiol 3.2015861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.3912752131
MESH:D011654 Pulmonary Edema Bleomycin 5.2115808516
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.8317177178 14609568 15322207 17434272 21435439 17241526 16314464 18008008 16115399 11554783 15541506 12574379 18162602 12624602
MESH:D015427 Reperfusion Injury pirinixic acid 2.3319058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7318990726
MESH:D012640 Seizures 2,4-dinitrotoluene 9.5918551238
MESH:D012640 Seizures Phenobarbital 9.5916876388 11442880 4039156 3137016
MESH:D012640 Seizures topiramate 9.5916499746
MESH:D003294 Seizures, Febrile Phenobarbital 4.716407741
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 1.9916192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8416709447
MESH:D019956 Stereotypic Movement Disorder Amphetamine 6.321977408
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013705 Temporomandibular Joint Disorders polyphenols 5.1517997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0615669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 5.0515790496
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.907505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 6.901399818
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.2416049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.2110091137
MESH:D014581 Urticaria Acetaminophen 2.8710982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1914692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4912125929
MESH:D014689 Venous Insufficiency coumarin 5.6712708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4415869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1415886252
MESH:D015431 Weight Loss Bleomycin 5.5312624602
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:14797 Signaling by GPCR
KEGG:04270 Vascular smooth muscle contraction
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA25187
    • No data
    Releated disease ID Related disease Name
    PA447198Autistic Disorder
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00035 - Desmopressin Renal Agents;Hemostatics;Antidiuretic Agents
    DB00067 - Vasopressin Antidiuretics;Vasoconstrictor Agents;Oxytocics
    DB00093 agonist Felypressin Renal Agents;Vasoconstrictor Agents
    DB00872 antagonist Conivaptan Aquaresis promoters
    DB02638 stimulator Terlipressin Vasoconstrictor Agents;Antihypertensive Agents
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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