AutismKB 2.0

Annotation Detail for PPP2R2A


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Basic Information Top
Gene Symbol:PPP2R2A ( B55A,B55ALPHA,DKFZp686N05117,FLJ26613,FLJ41727,MGC52248,PR52A,PR55A )
Gene Full Name: protein phosphatase 2, regulatory subunit B, alpha
Band: 8p21.2
Quick LinksEntrez ID:5520; OMIM: 604941; Uniprot ID:2ABA_HUMAN; ENSEMBL ID: ENSG00000221914; HGNC ID: 9304
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05160Hepatitis C
hsa05142Chagas disease
hsa04530Tight junction
No data
Pathway IDPathway Name
200113ErbB1 downstream signaling
200195TGF-beta receptor signaling
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of PPP2R2A mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of PPP2R2A mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of PPP2R2A mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PPP2R2A mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PPP2R2A mRNAdecreases expression 20018196
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PPP2R2A mRNAaffects cotreatment|decreases expression 20360939
D003024 Clozapine Clozapine results in decreased expression of PPP2R2A mRNAdecreases expression 15860345
D016572 Cyclosporine Cyclosporine results in increased expression of PPP2R2A mRNAincreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of PPP2R2A mRNAaffects cotreatment|decreases expression 20360939
D000431 Ethanol Ethanol results in decreased expression of PPP2R2A mRNAdecreases expression 17920746
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PPP2R2A mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP2R2A mRNAaffects cotreatment|increases expression 17942748
D005419 Flavonoids Flavonoids results in decreased expression of PPP2R2A mRNAdecreases expression 18035473
D006220 Haloperidol Haloperidol results in decreased expression of PPP2R2A mRNAdecreases expression 15860345
D008701 Methapyrilene Methapyrilene results in increased expression of PPP2R2A mRNAincreases expression 16393664
D015741 Metribolone Metribolone promotes the reaction [NDRG1 protein binds to PPP2R2A protein]affects binding|increases reaction 17220478
D015741 Metribolone Metribolone results in decreased expression of PPP2R2A proteindecreases expression 17152098
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of PPP2R2A mRNAincreases expression 17616710
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in decreased expression of PPP2R2A mRNAdecreases expression 16221955
C006253 pirinixic acid pirinixic acid results in increased expression of PPP2R2A mRNAincreases expression 18301758
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PPP2R2A mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 8.2717676605 18926900
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.2715322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 10.2718287403
MESH:D000138 Acidosis Ethanol 10.2711192467
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.0518653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8014692618
MESH:D000236 Adenoma Diethylnitrosamine 2.816695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.9316434500 17620307 18056438 19061943 17162532 19052882
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.9316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.9316835633
MESH:D000380 Agranulocytosis Clozapine 4.9914617031 12649775 16160616
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.2615451039 15451040
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8911748828
MESH:D000799 Angioedema Acetaminophen 3.7910982225
MESH:D000853 Anophthalmos Ethanol 4.7615513904
MESH:D001008 Anxiety Disorders Ethanol 3.9511141031
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6215885639
MESH:D001321 Autistic Disorder Acetaminophen 2.1218445737
MESH:D001321 Autistic Disorder Haloperidol 2.1219368416 18080171
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.5619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7215746008
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9817474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9820435547
MESH:D002056 Burns Ethanol 4.5916374292
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7416835633
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.7616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.7616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.763084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.7620935162 17173139 16779866 17138121 16698587 20727157 11831363 16288022 3581430 18665156 17428255 19919837 18785209 20514400 19539802 20432363 19822196 18506893 19701751 20214788 16830150 16569478 21159647 16935385 20524982 18971187 19335982 16681979 19519916 10672840 19383236 17055752 20007298 19052882 20084675 16878318 3084413 19171122 19107877 17162532 16807293 18056438 16540662 17978847 18978308 16502159 19394651 20101231 18393292 18788625 18494052 17761372 16328049 20512989 19208518 18691550 18210153 10737359 19418558
MESH:D006528 Carcinoma, Hepatocellular Ethanol 8.7615763234 15289165 18788625
MESH:D006332 Cardiomegaly Ethanol 6.7219332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.7218670907 18850075 16120746
MESH:D002375 Catalepsy Haloperidol 4.8515215559 1977408
MESH:D002386 Cataract Acetaminophen 2.5410977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.636135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 15.6320889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.6312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.6321159647 2727394 17174075 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.1319052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.1316835633
MESH:D002779 Cholestasis Cyclosporine 13.0519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.0516919318 15861022 16105132 17110522 17333356 11677210 17681005
MESH:D002779 Cholestasis pirinixic acid 13.0519176532
MESH:D002971 Cleft Lip Ethanol 3.5515513904
MESH:D002972 Cleft Palate Ethanol 5.8615513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8612621046 8697196 15668235 15340226 16354765
MESH:D003072 Cognition Disorders Clozapine 4.9017123785
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0017141729 14669216
MESH:D019465 Craniofacial Abnormalities Ethanol 2.6110194807 11198716 15451039 15513904 11873399 15451040 19302082
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.6115322242 20055451 10048152
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.6818551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.6818551238
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.7820210726
MESH:D003704 Dementia Haloperidol 4.5211575062
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 7.0816402076
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 7.0820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 7.0817107852
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.5015331141
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 15.0121346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.0121346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 15.0116485898 19420014 16081117 11529661 19085960 14725611 19370779 12540782 17906064 15619225 15968718 16781746 11421492 19416960 14986274 12705907 17562736 12153990 11834606 11461765 19164858 10774834 16109766 11739529 12958197 18071297 10915739 10663392 16393943 12392966 19739265 14550746 2444490 11743745 11287661 18713872 19923254 17522070 12594235 16177239 16227642
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 15.0119107877
MESH:D056486 Drug-Induced Liver Injury Ethanol 15.0111566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.0120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0419426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7111462148
MESH:D050171 Dyslipidemias Clozapine 4.1316402076
MESH:D004487 Edema pirinixic acid 6.3312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.3312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8518230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1212538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.969294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0616302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2820426865
MESH:D004938 Esophageal Neoplasms Ethanol 7.2816704527
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 7.2816510608 15150132 16704527 16805852 15547721 15623463 15878914 15547733 15264214
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9611564622
MESH:D005234 Fatty Liver Cyclosporine 23.9919224547
MESH:D005234 Fatty Liver Diethylnitrosamine 23.9921071580 20387270
MESH:D005234 Fatty Liver Ethanol 23.9919236843 18620774 16409862
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.9915345470
MESH:D005234 Fatty Liver pirinixic acid 23.9919236843 20131406
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.6117920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.2410194807 15451040 15513904 16946407
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3911858732
MESH:D005355 Fibrosis Cyclosporine 8.2712168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.2720067830
MESH:D005756 Gastritis Acetaminophen 10.9416983495
MESH:D005756 Gastritis Ethanol 10.9415046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.168708960
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 4.2217162496
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5410696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3011294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.5020558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2711000095
MESH:D006529 Hepatomegaly pirinixic acid 8.0516221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.0515340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9916354765 16959395 15340226 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 7.6316870215
MESH:D006930 Hyperalgesia Ethanol 7.6318783367
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D006948 Hyperkinesis Clozapine 4.8516046005
MESH:D006973 Hypertension Cyclosporine 4.8610903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8618850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4417937319
MESH:D007249 Inflammation Diethylnitrosamine 8.1118785209
MESH:D007249 Inflammation Flavonoids 8.1117296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.1112878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 2.5916306350
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.5310783313
MESH:D007569 Jaw Abnormalities Ethanol 9.9115513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.9116580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3915604871
MESH:D007674 Kidney Diseases Acetaminophen 9.8815629191 12587719
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 9.8815369732
MESH:D007674 Kidney Diseases Cyclosporine 9.888314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.0416705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 12.0416705839
MESH:D007680 Kidney Neoplasms Cyclosporine 12.0412371664
MESH:D007859 Learning Disorders Ethanol 4.1515451040
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 3.9516766008
MESH:D017880 Limb Deformities, Congenital Ethanol 3.7617676605
MESH:D008064 Lipidoses Clozapine 3.9117567588
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.7018407596 20032147 19638242 18522880 18665156
MESH:D008103 Liver Cirrhosis Ethanol 6.7015289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 5.0418295389
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 3.4218166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.4215474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4212878042
MESH:D008107 Liver Diseases Acetaminophen 3.8516611625 19460945 12969438 19014921 19784758 12587719 16610002 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 3.8517034775
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.5917347304 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1816871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 13.987678174
MESH:D008113 Liver Neoplasms Diethylnitrosamine 13.9820434301 20583210 20137499 19427195 18644402 19642983 12771043 19426721 21278145 20118626 2422723 21071580 19294768 20492335 19551842 18978307 18977376 19256749 19499222 20405173 18648771 19996281 20452335 19255062 15885732 21047994 19638242 9163691 20101389 19073162 19812893 2862719 12112319 16942905 20501860 21167192 19090486 10737359 19254457 19833225 18754104 19690152 19850985 15175105
MESH:D008113 Liver Neoplasms Methapyrilene 13.9815890375
MESH:D008113 Liver Neoplasms pirinixic acid 13.9820007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 13.9816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.542876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 9.5416842330 18775883 19126423 19009564 17174075 18079962 18093689 19539802 18282651 19004024 21159647 17854601 18253720 2563599 18164116 16267830 18308698 18544905 3124819 9362446 19519916 17942915
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.5412151625
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.2420970405 21163286 20512841 6695378
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.2411884234 19555203
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5019513568
MESH:D008569 Memory Disorders Ethanol 4.1215451040 18411066
MESH:D001523 Mental Disorders Clozapine 8.1616856516
MESH:D001523 Mental Disorders Haloperidol 8.1616856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.3519142101
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7316801185
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8916411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.1418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.1418551238 7678174
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.543581430 9029167
MESH:D009369 Neoplasms pirinixic acid 1.9217405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2319348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1514600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.9918514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.9920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0620387270
MESH:D009765 Obesity Clozapine 4.6518515891 19142110
MESH:D009765 Obesity pirinixic acid 4.6520558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.6912819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.6916049721
MESH:D010146 Pain Acetaminophen 2.3416870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.3616540662
MESH:D010190 Pancreatic Neoplasms Ethanol 5.3612384795
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1912520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4918163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.7512371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.752563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1311118676 11222880 11399792 11896295
MESH:D011537 Pruritus Ethinyl Estradiol 3.2516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D011595 Psychomotor Agitation Haloperidol 4.8911575062
MESH:D011618 Psychotic Disorders Clozapine 9.0015331141
MESH:D011618 Psychotic Disorders Haloperidol 9.0011575062
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7718990726
MESH:D012559 Schizophrenia Clozapine 4.0620452607 20580759 18855531 17726453 20107430 17667964 20521320 16141801 11151749 20168265 20521326 18806925 11763009 19369910 17123785
MESH:D012559 Schizophrenia Haloperidol 4.0620107430 18513383 19369910 1830565
MESH:D012640 Seizures 2,4-dinitrotoluene 9.6118551238
MESH:D012640 Seizures 2,6-dinitrotoluene 9.6118551238
MESH:D012640 Seizures Ethanol 9.619754883
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8916709447
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.4618456281
MESH:D013274 Stomach Neoplasms Ethanol 3.4618456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 3.4612958204 17575124
MESH:D013276 Stomach Ulcer Ethanol 3.4717189318 16755016 9562338 9211565 11906479 17918041
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.199754883
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.6420210726
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8512697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.937505956
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 4.9316049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 4.9316049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.7810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.7810091137
MESH:D014581 Urticaria Acetaminophen 2.9110982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014605 Uveitis Cyclosporine 3.931336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5412125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1915886252
MESH:D015430 Weight Gain Clozapine 4.4117502770 20564506 20521320 20107430 16141801 16402076
MESH:D015431 Weight Loss Clozapine 5.0217933447
MESH:D014985 Xerophthalmia Cyclosporine 4.3917120751
Pathway ID Pathway Name
KEGG:05142 Chagas disease (American trypanosomiasis)
KEGG:05160 Hepatitis C
KEGG:03015 mRNA surveillance pathway
KEGG:04530 Tight junction
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB02506 - 2,6,8-Trimethyl-3-Amino-9-Benzyl-9-Methoxynonanoic Acid
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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