AutismKB 2.0

Annotation Detail for SBNO1


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Basic Information Top
Gene Symbol:SBNO1 ( FLJ10701,FLJ10833,FLJ14066,FLJ16176,FLJ35199,MOP3,Sno )
Gene Full Name: strawberry notch homolog 1 (Drosophila)
Band: 12q24.31
Quick LinksEntrez ID:55206; OMIM: NA; Uniprot ID:SBNO1_HUMAN; ENSEMBL ID: ENSG00000139697; HGNC ID: 22973
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SBNO1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of SBNO1 mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of SBNO1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SBNO1 mRNAaffects expression 17562736
D002117 Calcitriol Calcitriol results in decreased expression of SBNO1 mRNAdecreases expression 16002434
C058305 phenethyl isothiocyanate phenethyl isothiocyanate results in decreased expression of SBNO1 mRNAdecreases expression 17616710
D015032 Zinc Zinc results in increased expression of SBNO1 mRNAincreases expression 16870260
C016837 zinc chloride zinc chloride results in increased expression of SBNO1 mRNAincreases expression 16870260
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 4.287525203
MESH:D000169 Acrodermatitis Zinc 5.7417190629 17202136 16889938
MESH:D000544 Alzheimer Disease Zinc 2.8016325427 16580781 17119284 16410023
MESH:D000755 Anemia, Sickle Cell Zinc 5.1816916123
MESH:D000799 Angioedema Acetaminophen 4.2210982225
MESH:D001249 Asthma Zinc 3.0117085522
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001930 Brain Injuries Zinc 5.0017109824
MESH:D001943 Breast Neoplasms Calcitriol 2.5811237771
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.6916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.6916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.693084413
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 5.2011237771
MESH:D002294 Carcinoma, Squamous Cell Zinc 5.2016543248
MESH:D002318 Cardiovascular Diseases Zinc 3.8216936243
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.8514694615
MESH:D002386 Cataract Acetaminophen 7.8510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.936135515
MESH:D003093 Colitis, Ulcerative phenethyl isothiocyanate 3.7120423518
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 4.3715095906
MESH:D019465 Craniofacial Abnormalities Zinc 2.4419302082
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.9418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.9418551238
MESH:D003920 Diabetes Mellitus Zinc 4.4216479319
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.5121346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.5118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 9.5121346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.5116177239 15968718 16485898 11461765 11743745 18071297 11834606 12153990 15619225 17906064 10774834 14725611 16227642 16781746 14986274 10915739 19923254 17522070 16393943 10663392 17562736 11421492 16081117 11287661 11739529 12705907 19370779 12540782 12594235 12958197 16109766 14550746 19164858 11529661 12392966 19739265 19420014 19416960 18713872 19085960 2444490
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4719426721
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.2115138306
MESH:D004938 Esophageal Neoplasms Zinc 2.9116543248
MESH:D005756 Gastritis Acetaminophen 12.4616983495
MESH:D005756 Gastritis Zinc 12.4617241300
MESH:D006130 Growth Disorders Zinc 4.1017217573
MESH:D006333 Heart Failure Zinc 3.7417162251
MESH:D006335 Heart Injuries Zinc 6.1517074742
MESH:D016481 Helicobacter Infections Zinc 4.7917241300
MESH:D006527 Hepatolenticular Degeneration Zinc 5.0017276780
MESH:D006930 Hyperalgesia Acetaminophen 2.8916870215
MESH:D007511 Ischemia Zinc 4.9416584753
MESH:D007674 Kidney Diseases Acetaminophen 6.5812587719 15629191
MESH:D007674 Kidney Diseases Zinc 6.5816960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.6616518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.0416705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.0416705839
MESH:D008107 Liver Diseases Acetaminophen 1.6719784758 16610002 19460945 12587719 11587558 12969438 19014921 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4617185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.227678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.682876784 6135515 2876786
MESH:D008325 Mammary Neoplasms, Experimental Zinc 3.4412773700
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8719513568
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.5018551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.5018551238 7678174
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0718514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 16.5312819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 16.5316049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 16.5314694615
MESH:D010146 Pain Acetaminophen 2.5916870215
MESH:D011225 Pre-Eclampsia Zinc 4.3617114810
MESH:D011470 Prostatic Hyperplasia Calcitriol 5.1215572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.5318247401 16289102 16644109 15754350 12479363
MESH:D011471 Prostatic Neoplasms Zinc 3.5316606632 12429649 16700911 16517595
MESH:D012162 Retinal Degeneration Zinc 4.3016584753
MESH:D012640 Seizures 2,4-dinitrotoluene 6.3918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.3918551238
MESH:D013733 Testicular Diseases phenethyl isothiocyanate 5.2815864552
MESH:D014062 Tongue Neoplasms Zinc 4.6316543248
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.2816049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.2816049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.1410091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.1410091137
MESH:D014581 Urticaria Acetaminophen 3.2410982225
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134967986
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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