Gene Symbol:	BBS7 ( BBS2L1,FLJ10715 )
Gene Full Name:	Bardet-Biedl syndrome 7
Band:	4q27
Quick Links	Entrez ID:55212; OMIM: 607590; Uniprot ID:BBS7_HUMAN; ENSEMBL ID: ENSG00000138686; HGNC ID: 18758
Relate to Another Database:	SFARIGene; denovo-db

Desease ID	Desease Name
	Other genetic disorders
H00418	Bardet-Biedl syndrome
	Genetic disorders

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
C023514	2,6-dinitrotoluene	2,6-dinitrotoluene affects the expression of BBS7 mRNA	affects expression	21346803
D016604	Aflatoxin B1	Aflatoxin B1 affects the expression of BBS7 protein	affects expression	20106945
D004041	Dietary Fats	Dietary Fats results in decreased expression of BBS7 mRNA	decreases expression	18042831
C041786	palm oil	palm oil results in decreased expression of BBS7 mRNA	decreases expression	18042831
D011374	Progesterone	Progesterone results in increased expression of BBS7 mRNA	increases expression	18070364

Disease ID	Disease Name	Direct Evidence	Inference Chemical Name	Inference Score	Publication
MESH:D001161	Arteriosclerosis		Dietary Fats	4.37	15238619
MESH:D020788	Bardet-Biedl Syndrome	marker/mechanism
MESH:D020201	Brain Hemorrhage, Traumatic		Progesterone	5.95	17868700
MESH:D001930	Brain Injuries		Progesterone	4.74	15845082 15380490 15665606
MESH:D001943	Breast Neoplasms		Dietary Fats	2.23	20435547
MESH:D001943	Breast Neoplasms		Progesterone	2.23	15562024 16175315 17614352
MESH:D006528	Carcinoma, Hepatocellular		2,6-dinitrotoluene	3.16	16705839
MESH:D006528	Carcinoma, Hepatocellular		Aflatoxin B1	3.16	12907637 21507988 12619106
MESH:D002471	Cell Transformation, Neoplastic		2,6-dinitrotoluene	3.00	6135515
MESH:D003490	Cyanosis		2,6-dinitrotoluene	4.50	18551238
MESH:D003929	Diabetic Neuropathies		Progesterone	4.98	17187935
MESH:D056486	Drug-Induced Liver Injury		2,6-dinitrotoluene	2.04	21346803 18551238
MESH:D050171	Dyslipidemias		Dietary Fats	3.70	18367378
MESH:D004681	Encephalomyelitis, Autoimmune, Experimental		Progesterone	4.22	17692515
MESH:D004715	Endometriosis		Progesterone	4.11	16134523
MESH:D005234	Fatty Liver		Dietary Fats	3.61	18296743 17967931 19004024 19551842
MESH:D005355	Fibrosis		Dietary Fats	4.01	18296743
MESH:D006937	Hypercholesterolemia		Dietary Fats	3.97	21332399
MESH:D006949	Hyperlipidemias		Dietary Fats	4.02	21332399
MESH:D020244	Infarction, Middle Cerebral Artery		Progesterone	4.89	15869954
MESH:D007249	Inflammation		Dietary Fats	5.73	20412841
MESH:D007249	Inflammation		Progesterone	5.73	15869954
MESH:D007333	Insulin Resistance		Dietary Fats	3.32	11836018 18457598
MESH:D007680	Kidney Neoplasms		2,6-dinitrotoluene	3.28	16705839
MESH:D008103	Liver Cirrhosis		Dietary Fats	3.05	18296743
MESH:D008113	Liver Neoplasms		2,6-dinitrotoluene	4.97	7678174
MESH:D008113	Liver Neoplasms		Aflatoxin B1	4.97	18177683 15890375 9163691 2125692
MESH:D008114	Liver Neoplasms, Experimental		2,6-dinitrotoluene	6.65	2876786 2876784 6135515
MESH:D008114	Liver Neoplasms, Experimental		Aflatoxin B1	6.65	8603461
MESH:D008175	Lung Neoplasms		Aflatoxin B1	1.88	14755239
MESH:D008325	Mammary Neoplasms, Experimental		Progesterone	3.07	11408345 17203775
MESH:D009336	Necrosis		2,6-dinitrotoluene	4.40	7678174 18551238
MESH:D009765	Obesity		Dietary Fats	2.35	21332399 18457598 20132043 16723640 19632207 17217161 18674790 11836018 20518802
MESH:D009784	Occupational Diseases		2,6-dinitrotoluene	3.78	16049721
MESH:D010051	Ovarian Neoplasms		Progesterone	2.61	17393432 16525653
MESH:D012468	Salivary Gland Neoplasms		Progesterone	2.95	18045962
MESH:D012640	Seizures		2,6-dinitrotoluene	2.76	18551238
MESH:D013119	Spinal Cord Injuries		Progesterone	4.82	15862959 16503802
MESH:D001749	Urinary Bladder Neoplasms		2,6-dinitrotoluene	2.40	16049721
MESH:D014571	Urologic Neoplasms		2,6-dinitrotoluene	4.86	10091137
MESH:D015430	Weight Gain		Dietary Fats	4.06	16723640

AutismKB 2.0

Annotation Detail for BBS7

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics