Gene Symbol:	NAT10 ( ALP,DKFZp434C116,FLJ10774,FLJ12179,FLJ23850,KIAA1709,NET43 )
Gene Full Name:	N-acetyltransferase 10 (GCN5-related)
Band:	11p13
Quick Links	Entrez ID:55226; OMIM: 609221; Uniprot ID:NAT10_HUMAN; ENSEMBL ID: ENSG00000135372; HGNC ID: 29830
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NAT10 mRNA	decreases expression	20382639 19150397
C010327	salinomycin	salinomycin results in decreased expression of NAT10 mRNA	decreases expression	19682730
C066340	tolcapone	tolcapone binds to NAT10 protein	affects binding	19783845

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D017109	Akathisia, Drug-Induced	tolcapone	7.16	11080934
MESH:D000544	Alzheimer Disease	tolcapone	3.35	20150427
MESH:D001943	Breast Neoplasms	salinomycin	3.31	19682730
MESH:D002471	Cell Transformation, Neoplastic	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	3.01	20889678
MESH:D003866	Depressive Disorder	tolcapone	4.61	7768276 11224284
MESH:D003865	Depressive Disorder, Major	tolcapone	5.32	10440460
MESH:D056486	Drug-Induced Liver Injury	tolcapone	3.32	16604736 19783845
MESH:D004409	Dyskinesia, Drug-Induced	tolcapone	6.26	11455177
MESH:D004938	Esophageal Neoplasms	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	2.15	20426865
MESH:D054908	Extensively Drug-Resistant Tuberculosis	tolcapone	6.81	19578428
MESH:D008325	Mammary Neoplasms, Experimental	salinomycin	4.03	19682730
MESH:D010300	Parkinson Disease	tolcapone	3.72	10651109 19578428 11432539 7566641 9305320 11586115 17089403 19783845 20216409 8739811 1977408 20334432 9708959 18328768 9333106 9754991 9591521 11746615 8635184 16758261 11793426
MESH:D018088	Tuberculosis, Multidrug-Resistant	tolcapone	6.81	19578428
MESH:D014820	Vitiligo	tolcapone	5.77	10573327

AutismKB 2.0

Annotation Detail for NAT10