AutismKB 2.0

Annotation Detail for MOBKL1B


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Basic Information Top
Gene Symbol:MOBKL1B ( C2orf6,FLJ10788,FLJ11595,MATS1,MOB1,MOBK1B,Mob4B )
Gene Full Name: MOB1, Mps One Binder kinase activator-like 1B (yeast)
Band: 2p13.1
Quick LinksEntrez ID:55233; OMIM: 609281; Uniprot ID:MOL1B_HUMAN; ENSEMBL ID: ENSG00000114978; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of MOBKL1B mRNAdecreases expression 12958071
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of MOBKL1B mRNAincreases expression 18648102
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MOBKL1B mRNAdecreases expression 15336504
C099555 CD 437 CD 437 results in decreased expression of MOBKL1B mRNAdecreases expression 12958071
C006253 pirinixic acid pirinixic acid results in decreased expression of MOBKL1B mRNAdecreases expression 18445702
17426115
C025643 vinclozolin vinclozolin affects the expression of MOBKL1B mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.4718653653
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.923712494
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.9416434500
MESH:D001008 Anxiety Disorders vinclozolin 3.8919015723
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.541440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4719483382
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.777296757 3581430
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.807296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 2.967505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.6219486331 9022650
MESH:D002779 Cholestasis pirinixic acid 8.6219176532
MESH:D003456 Cryptorchidism vinclozolin 4.7214966744
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.2114531868 18759878 8970840 8156756 11906362 12868966 11298694 2524372
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.843621924 2952479
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.039022650 1440618 18289764 7440962 18692083 6679447 6482804 9653073 11289319 16192314 8291058 18648102 9328219
MESH:D004487 Edema pirinixic acid 2.8012083418
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.173581430
MESH:D005234 Fatty Liver pirinixic acid 3.0919236843 20131406
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.546705139
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.4016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.8216417039
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.397505956
MESH:D006333 Heart Failure pirinixic acid 2.7120558911
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.896705139
MESH:D006529 Hepatomegaly pirinixic acid 3.4116221962 18467677 19176532 19772884
MESH:D006943 Hyperglycemia pirinixic acid 3.4920558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.3615034207
MESH:D007248 Infertility, Male vinclozolin 3.2416467254
MESH:D007333 Insulin Resistance pirinixic acid 2.8216306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.549022650 8074119
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.236582329
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1916417039
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.3815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9120007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.71598648 3712494 1399818 6587162
MESH:D009135 Muscular Diseases pirinixic acid 3.9216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2519151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1916411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.573581430
MESH:D009369 Neoplasms pirinixic acid 2.0817405874
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.106679447
MESH:D009765 Obesity pirinixic acid 1.8720558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.724026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.543988306
MESH:D010051 Ovarian Neoplasms CD 437 3.3917474084
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.907296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.996228378
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.3618042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.4018220299
MESH:D011472 Prostatitis vinclozolin 5.4018629315
MESH:D015427 Reperfusion Injury pirinixic acid 2.5219058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.613692021
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.818532709
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.126582329 1399818 7505956 6587162 3712494
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 5.768074119
MESH:D001749 Urinary Bladder Neoplasms CD 437 5.7616720286
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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