AutismKB 2.0

Annotation Detail for CCDC25


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Basic Information Top
Gene Symbol:CCDC25 ( FLJ10853 )
Gene Full Name: coiled-coil domain containing 25
Band: 8p21.1
Quick LinksEntrez ID:55246; OMIM: NA; Uniprot ID:CCD25_HUMAN; ENSEMBL ID: ENSG00000147419; HGNC ID: 25591
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
smoking cessation
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CCDC25 mRNAaffects expression 17562736
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of CCDC25 mRNAdecreases expression 15336504
D016572 Cyclosporine Cyclosporine results in decreased expression of CCDC25 mRNAdecreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.8212371664
MESH:D002779 Cholestasis Cyclosporine 3.2419486331
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6817906064 11529661 12153990 15619225 11739529 16227642 11743745 11834606 12540782 12958197 18713872 14550746 18071297 12594235 12705907 11421492 19739265 19164858 11287661 17522070 16081117 19923254 19416960 16393943 11461765 19370779 10915739 10774834 16109766 10663392 16781746 19420014 14725611 17562736 16177239 12392966 15968718 16485898 19085960 2444490 14986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D005234 Fatty Liver Cyclosporine 3.3419224547
MESH:D005355 Fibrosis Cyclosporine 3.7912639820 12168785
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Acetaminophen 6.5512587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 6.5510903974 8314463 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.1212371664
MESH:D008107 Liver Diseases Acetaminophen 1.7116611625 19460945 11587558 12969438 12587719 19014921 16610002 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7019348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011565 Psoriasis Cyclosporine 2.3416882103
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.868532709
MESH:D014581 Urticaria Acetaminophen 3.5010982225
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018