AutismKB 2.0

Annotation Detail for GIMAP5


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Basic Information Top
Gene Symbol:GIMAP5 ( FLJ11296,HIMAP3,IAN4,IAN4L1,IAN5,IMAP3,hIAN5 )
Gene Full Name: GTPase, IMAP family member 5
Band: 7q36.1
Quick LinksEntrez ID:55340; OMIM: 608086; Uniprot ID:GIMA5_HUMAN; ENSEMBL ID: ENSG00000196329; HGNC ID: 18005
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
IMMUNE
lupus erythematosus
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of GIMAP5 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of GIMAP5 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GIMAP5 mRNAaffects expression 16483693
D003913 Dextroamphetamine Dextroamphetamine results in increased expression of GIMAP5 mRNAincreases expression 16715494
C006780 bisphenol A bisphenol A results in increased expression of GIMAP5 mRNAincreases expression 18180321
D003024 Clozapine Clozapine results in decreased expression of GIMAP5 mRNAdecreases expression 16715494
D006220 Haloperidol Haloperidol results in decreased expression of GIMAP5 mRNAdecreases expression 16715494
C025643 vinclozolin vinclozolin affects the expression of GIMAP5 mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of GIMAP5 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.8418287403
MESH:D000380 Agranulocytosis Clozapine 5.3114617031 12649775 16160616
MESH:D000799 Angioedema Acetaminophen 4.1610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.8019015723
MESH:D001321 Autistic Disorder Acetaminophen 2.1318445737
MESH:D001321 Autistic Disorder Haloperidol 2.1318080171 19368416
MESH:D001862 Bone Resorption bisphenol A 4.0711985600
MESH:D001943 Breast Neoplasms bisphenol A 2.4517123778
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.1916050911
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 2.9016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.903084413
MESH:D002278 Carcinoma in Situ bisphenol A 5.2717123778
MESH:D002375 Catalepsy Haloperidol 5.191977408 15215559
MESH:D002386 Cataract Acetaminophen 2.6910977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.906135515
MESH:D003072 Cognition Disorders Clozapine 5.2217123785
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003456 Cryptorchidism vinclozolin 4.5814966744
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.2818551238
MESH:D016757 Death, Sudden, Cardiac Haloperidol 5.0620210726
MESH:D003704 Dementia Haloperidol 4.7811575062
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 3.0116402076
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.8715331141
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.8918551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.8912392966 11421492 16109766 12958197 15619225 11461765 10774834 17906064 18713872 10915739 17562736 17522070 11739529 12540782 11743745 11287661 12594235 16227642 19370779 14550746 11529661 19739265 16393943 16781746 19164858 16081117 16485898 19416960 19923254 18071297 2444490 11834606 10663392 14986274 19420014 12153990 12705907 16177239 19085960 14725611 15968718
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4219426721
MESH:D050171 Dyslipidemias Clozapine 4.3316402076
MESH:C538011 Eales disease Vitamin E 5.029068938
MESH:D005756 Gastritis Acetaminophen 3.9916983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.2216973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.6216417039
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0816080930
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7616490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.2914716179
MESH:D006930 Hyperalgesia Acetaminophen 2.8616870215
MESH:D006948 Hyperkinesis Clozapine 5.1916046005
MESH:D007248 Infertility, Male vinclozolin 3.1716467254
MESH:D007251 Influenza, Human Vitamin E 4.5316624496
MESH:D007333 Insulin Resistance bisphenol A 3.4116393666
MESH:D007674 Kidney Diseases Acetaminophen 6.3312587719 15629191
MESH:D007674 Kidney Diseases Vitamin E 6.3312488133
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.1516705839
MESH:D007984 Leydig Cell Tumor vinclozolin 5.0216417039
MESH:D008064 Lipidoses Clozapine 4.1017567588
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008107 Liver Diseases Acetaminophen 1.6719784758 12587719 19014921 16610002 12969438 16611625 19460945 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4317185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.217678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.662876784 6135515 2876786
MESH:D008171 Lung Diseases Vitamin E 3.3116863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8319513568
MESH:D001523 Mental Disorders Clozapine 9.3316856516
MESH:D001523 Mental Disorders Haloperidol 9.3316856516
MESH:D024821 Metabolic Syndrome X Clozapine 4.5819142101
MESH:D009041 Motion Sickness Dextroamphetamine 5.841613127
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.157678174 18551238
MESH:D009421 Nervous System Malformations bisphenol A 4.2111399458 16427766
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0418514411
MESH:D009765 Obesity Clozapine 3.0618515891 19142110
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.6216049721
MESH:D010049 Ovarian Diseases bisphenol A 5.2711985600
MESH:D010146 Pain Acetaminophen 2.5616870215
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 10.7410548101
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 10.7418220299 18042343 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.2218220299
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.4120887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3016740699
MESH:D011471 Prostatic Neoplasms Vitamin E 3.3015084515
MESH:D011472 Prostatitis vinclozolin 5.2218629315
MESH:D011595 Psychomotor Agitation Haloperidol 5.2111575062
MESH:D011618 Psychotic Disorders Clozapine 9.6415331141
MESH:D011618 Psychotic Disorders Haloperidol 9.6411575062
MESH:D011629 Puberty, Precocious bisphenol A 5.0710548101
MESH:D012559 Schizophrenia Clozapine 4.1818855531 17123785 11763009 19369910 20580759 20168265 20521326 20521320 17726453 16141801 20107430 11151749 20452607 17667964 18806925
MESH:D012559 Schizophrenia Haloperidol 4.1819369910 1830565 18513383 20107430
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6718551238
MESH:D012871 Skin Diseases Vitamin E 2.4818709164
MESH:D020521 Stroke Vitamin E 3.6816517955
MESH:D019966 Substance-Related Disorders bisphenol A 4.2716684133 16045194
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.9420210726
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3516049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.6010091137
MESH:D014581 Urticaria Acetaminophen 3.2010982225
MESH:D014591 Uterine Diseases bisphenol A 5.3314652134
MESH:D015430 Weight Gain Clozapine 4.6520107430 20521320 17502770 16141801 16402076 20564506
MESH:D015431 Weight Loss Clozapine 5.3617933447
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA29578
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    PA444822Lupus Erythematosus, Systemic
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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