Annotation Detail for LSG1
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of LSG1 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of LSG1 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of LSG1 mRNA | affects expression | 17562736
|
| D012402 |
Rotenone |
Rotenone results in decreased expression of LSG1 mRNA | decreases expression | 19013527
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of LSG1 mRNA | affects expression | 19015723
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
3.93 | 19015723 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.76 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.76 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
4.76 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.00 | 6135515 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.78 | 14966744 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.56 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.56 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.67 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.67 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.67 | 14725611 16177239 16781746 12958197 12153990 10774834 15619225 14986274 12594235 11834606 19370779 16227642 16485898 16109766 12392966 15968718 18713872 10915739 16393943 19416960 2444490 16081117 14550746 11461765 19923254 18071297 11743745 11287661 19420014 12705907 17562736 11421492 19164858 17906064 10663392 17522070 19739265 19085960 11739529 11529661 12540782 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.47 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
5.91 | 16417039 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.26 | 16467254 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 15629191 12587719 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.39 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.39 | 16705839 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.27 | 16417039 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 19014921 16610002 12969438 12587719 19784758 16611625 19460945 11587558 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.25 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.74 | 2876784 2876786 6135515 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.21 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
12.21 | 18551238 7678174 |
| MESH:D009410 |
Nerve Degeneration |
|
Rotenone |
4.15 | 15790535 18619942 17356569 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.06 | 12819281 16049721 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.06 | 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D010300 |
Parkinson Disease |
|
Rotenone |
3.08 | 11445065 19232380 15451049 18619942 11535288 16140633 19114014 16412576 18191903 |
| MESH:D020734 |
Parkinsonian Disorders |
|
Rotenone |
4.42 | 15574749 15927086 18197244 15795934 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.44 | 18220299 18042343 19015723 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.47 | 18220299 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.47 | 18629315 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.65 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.65 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.39 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.39 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.86 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.86 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:03008 |
Ribosome biogenesis in eukaryotes |
Related Pathway Information