AutismKB 2.0

Annotation Detail for SLC35C1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SLC35C1 ( CDG2C,FLJ11320,FLJ14841,FUCT1 )
Gene Full Name: solute carrier family 35, member C1
Band: 11p11.2
Quick LinksEntrez ID:55343; OMIM: 605881; Uniprot ID:FUCT1_HUMAN; ENSEMBL ID: ENSG00000181830; HGNC ID: 20197
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Transmembrane transport of small molecules
No data
No data
Pathway IDPathway Name
500363Transport of nucleotide sugars
Related Diseases/Disorders Top
Desease IDDesease Name
H00099Leukocyte adhesion deficiency
Immune system diseases
Inherited disorders of glycan/glycoprotein metabolism
Primary immunodeficiency
H00119Congenital disorders of glycosylation (CDG) type II
Genetic disorders
No data
No data
No data
Desease Name
Congenital disorder of glycosylation, type IIc
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SLC35C1 mRNAaffects expression 17562736
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of SLC35C1 mRNAaffects cotreatment|increases expression 17183730
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of SLC35C1 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.238875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.4119490988
MESH:D000550 Amblyopia Valproic Acid 6.1017688650
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001008 Anxiety Disorders Valproic Acid 3.9417497229
MESH:D001321 Autistic Disorder Acetaminophen 1.8618445737
MESH:D001321 Autistic Disorder Valproic Acid 1.8620603192 18177632 19232924 17688650 19460635 18940202 18558336 18316065 18985861 17157402 15238991 18396377 18775368 17507914 16609825
MESH:D001714 Bipolar Disorder Valproic Acid 3.2617594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.668888407
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8320734317
OMIM:266265 CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIc marker/mechanism
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9116575769 8888407 17688650
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.1319420014 19739265 11421492 11529661 19923254 18071297 10774834 19416960 2444490 14725611 17562736 11739529 16109766 10915739 16393943 12705907 17522070 11743745 12392966 14986274 16081117 17906064 10663392 11461765 19164858 11834606 19085960 16227642 12958197 11287661 12153990 14550746 12594235 16781746 16177239 12540782 15619225 18713872 15968718 16485898 19370779
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 4.131733752 19641884
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D004421 Dystonia Valproic Acid 4.581851702
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.8117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 4.783922381 16628512
MESH:D004827 Epilepsy Valproic Acid 3.1220417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 4.006426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.957750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.813659116
MESH:D005234 Fatty Liver Valproic Acid 3.7819224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.7516575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.718888407 18558336
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006849 Hydrocephalus Valproic Acid 5.6117688650
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 5.2816612254
MESH:D007674 Kidney Diseases Acetaminophen 2.4212587719 15629191
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.2016294345 17596541
MESH:D008107 Liver Diseases Acetaminophen 1.7119784758 16611625 19460945 11587558 19014921 16610002 12969438 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 5.1317228818
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D008881 Migraine Disorders Valproic Acid 3.5018765137 18803445
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.518888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3717596541
MESH:D009436 Neural Tube Defects Valproic Acid 3.398888407 16359493
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.5720603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.4112752131 11422049
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.7019155313
MESH:D012559 Schizophrenia Valproic Acid 2.1119110320 15737665
MESH:D012640 Seizures Valproic Acid 3.0211044598 11738929 1511512 17978042 16876388 15475178 14763951 3137016
MESH:D016135 Spinal Dysraphism Valproic Acid 4.1319490988
MESH:D013226 Status Epilepticus Valproic Acid 5.4112833885
MESH:D014178 Translocation, Genetic Valproic Acid 6.1017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.263119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.308888407
MESH:D014581 Urticaria Acetaminophen 3.5010982225
Pathway ID Pathway Name
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved