AutismKB 2.0

Annotation Detail for PPP3R2


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Basic Information Top
Gene Symbol:PPP3R2 ( PPP3RL )
Gene Full Name: protein phosphatase 3, regulatory subunit B, beta
Band: 9q31.1
Quick LinksEntrez ID:5535; OMIM: NA; Uniprot ID:CANB2_HUMAN; ENSEMBL ID: ENSG00000188386; HGNC ID: 9318
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa04720Long-term potentiation
hsa04360Axon guidance
hsa04650Natural killer cell mediated cytotoxicity
hsa04020Calcium signaling pathway
hsa04310Wnt signaling pathway
hsa05014Amyotrophic lateral sclerosis (ALS)
hsa05010Alzheimer's disease
hsa04114Oocyte meiosis
hsa04210Apoptosis
hsa04370VEGF signaling pathway
hsa04660T cell receptor signaling pathway
hsa04662B cell receptor signaling pathway
No data
No data
Pathway IDPathway Name
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PPP3R2 mRNAaffects expression 16483693
D005419 Flavonoids Flavonoids results in increased expression of PPP3R2 mRNAincreases expression 18035473
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D007249 Inflammation Flavonoids 2.8617296493
Pathway ID Pathway Name
KEGG:05010 Alzheimer's disease
KEGG:05014 Amyotrophic lateral sclerosis (ALS)
KEGG:04210 Apoptosis
KEGG:04360 Axon guidance
KEGG:04662 B cell receptor signaling pathway
KEGG:04020 Calcium signaling pathway
KEGG:04724 Glutamatergic synapse
KEGG:04720 Long-term potentiation
KEGG:04010 MAPK signaling pathway
KEGG:04650 Natural killer cell mediated cytotoxicity
KEGG:04114 Oocyte meiosis
KEGG:04660 T cell receptor signaling pathway
KEGG:05152 Tuberculosis
KEGG:04370 VEGF signaling pathway
KEGG:04310 Wnt signaling pathway
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00091 antagonist Cyclosporine Antirheumatic Agents;Immunomodulatory Agents;Enzyme Inhibitors;Dermatologic Agents;Immunosuppressive Agents;Antifungal Agents
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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